MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 003 595–3 163 595 bp (160 000 bp)
+ strand − strand Rv2661c (Rv2661c) — dark: hypothetical protein Rv2662 (Rv2662) — dark: hypothetical protein Rv2663 (Rv2663) — requalified: hypothetical protein Rv2664 (Rv2664) — family_assigned: hypothetical protein Rv2665 (Rv2665) — requalified: arginine RICH protein Rv2668 (Rv2668) — family_assigned: hypothetical protein Rv2669 (Rv2669) — requalified: N-acetyltransferase zapE (Rv2670c) — requalified: cell division protein ZapE ribD (Rv2671) — requalified: bifunctional diaminohydroxyphosphoribosylaminopyrimidine dea Rv2672 (Rv2672) — requalified: alpha/beta fold hydrolase aftC (Rv2673) — requalified: arabinofuranan 3-O-arabinosyltransferase msrB (Rv2674) — requalified: peptide-methionine (R)-S-oxide reductase MsrB Rv2675c (Rv2675c) — requalified: class I SAM-dependent methyltransferase hemQ (Rv2676c) — requalified: hydrogen peroxide-dependent heme synthase hemE (Rv2678c) — requalified: uroporphyrinogen decarboxylase echA15 (Rv2679) — family_assigned: enoyl-CoA hydratase/isomerase family protein Rv2680 (Rv2680) — dark: DUF3000 domain-containing protein Rv2681 (Rv2681) — requalified: ribonuclease D arsA (Rv2684) — family_assigned: ArsB/NhaD family transporter Rv2686c (Rv2686c) — family_assigned: fluoroquinolones efflux ABC transporter permease Rv2687c (Rv2687c) — family_assigned: fluoroquinolone transporter permease Rv2688c (Rv2688c) — family_assigned: ABC transporter ATP-binding protein Rv2689c (Rv2689c) — requalified: class I SAM-dependent RNA methyltransferase Rv2693c (Rv2693c) — dark: DUF3159 domain-containing protein Rv2694c (Rv2694c) — family_assigned: OB-fold nucleic acid binding domain-containing protein Rv2695 (Rv2695) — requalified: alpha/beta fold hydrolase Rv2696c (Rv2696c) — dark: DUF3710 domain-containing protein Rv2698 (Rv2698) — dark: DUF3093 domain-containing protein Rv2699c (Rv2699c) — dark: DUF4193 domain-containing protein cei (Rv2700) — requalified: envelope integrity protein Cei suhB (Rv2701c) — requalified: inositol-1-monophosphatase SuhB ppgK (Rv2702) — family_assigned: ROK family protein sigA (Rv2703) — requalified: RNA polymerase sigma factor Rv2704 (Rv2704) — family_assigned: RidA family protein Rv2705c (Rv2705c) — family_assigned: DUF952 domain-containing protein Rv2706c (Rv2706c) — dark: hypothetical protein Rv2707 (Rv2707) — family_assigned: YihY/virulence factor BrkB family protein Rv2709 (Rv2709) — dark: DUF3099 domain-containing protein sigB (Rv2710) — family_assigned: sigma-70 family RNA polymerase sigma factor SigB ideR (Rv2711) — family_assigned: iron-dependent transcriptional regulator IdeR Rv2712c (Rv2712c) — dark: DUF4192 domain-containing protein sthA (Rv2713) — requalified: Si-specific NAD(P)(+) transhydrogenase Rv2714 (Rv2714) — family_assigned: PAC2 family protein Rv2715 (Rv2715) — family_assigned: alpha/beta hydrolase Rv2716 (Rv2716) — family_assigned: PhzF family phenazine biosynthesis protein Rv2717c (Rv2717c) — family_assigned: FABP family protein nrdR (Rv2718c) — family_assigned: transcriptional regulator NrdR chiZ (Rv2719c) — requalified: cell wall hydrolase ChiZ lexA (Rv2720) — requalified: transcriptional repressor LexA Rv2721c (Rv2721c) — family_assigned: LGFP repeat-containing protein Rv2722 (Rv2722) — dark: hypothetical protein Rv2723 (Rv2723) — family_assigned: TerC/Alx family metal homeostasis membrane protein fadE20 (Rv2724c) — family_assigned: acyl-CoA dehydrogenase family protein dapF (Rv2726c) — requalified: diaminopimelate epimerase miaA (Rv2727c) — requalified: tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA Rv2728c (Rv2728c) — family_assigned: hypothetical protein Rv2729c (Rv2729c) — family_assigned: DMT family transporter Rv2730 (Rv2730) — dark: hypothetical protein Rv2731 (Rv2731) — family_assigned: DUF349 domain-containing protein Rv2732c (Rv2732c) — family_assigned: hypothetical protein miaB (Rv2733c) — requalified: tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase Rv2734 (Rv2734) — family_assigned: DUF5131 family protein Rv2735c (Rv2735c) — requalified: three-Cys-motif partner protein TcmP recX (Rv2736c) — requalified: recombination regulator RecX recA (Rv2737c) — requalified: intein-containing recombinase RecA Rv2738c (Rv2738c) — family_assigned: DUF3046 domain-containing protein Rv2739c (Rv2739c) — requalified: glycosyltransferase ephG (Rv2740) — requalified: epoxide hydrolase Rv2743c (Rv2743c) — family_assigned: hypothetical protein clgR (Rv2745c) — family_assigned: transcriptional regulator ClgR argA (Rv2747) — requalified: amino-acid N-acetyltransferase ftsK (Rv2748c) — requalified: DNA translocase FtsK Rv2749 (Rv2749) — family_assigned: putative quinol monooxygenase Rv2750 (Rv2750) — family_assigned: Rv2750 family mycofactocin-dependent SDR oxidoreductase Rv2751 (Rv2751) — requalified: class I SAM-dependent methyltransferase rnj (Rv2752c) — requalified: ribonuclease J dapA (Rv2753c) — requalified: 4-hydroxy-tetrahydrodipicolinate synthase thyX (Rv2754c) — requalified: FAD-dependent thymidylate synthase hsdM (Rv2756c) — requalified: class I SAM-dependent DNA methyltransferase vapC21 (Rv2757c) — requalified: type II toxin-antitoxin system toxin ribonuclease C21 vapB21 (Rv2758c) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC42 (Rv2759c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB42 (Rv2760c) — family_assigned: type II toxin-antitoxin system VapB family antitoxin hsdS (Rv2761c) — family_assigned: restriction endonuclease subunit S Rv2762c (Rv2762c) — family_assigned: winged helix-turn-helix domain-containing protein qcrA (Rv2195) — requalified: hypothetical protein dfrA (Rv2763c) — requalified: dihydrofolate reductase Rv2765 (Rv2765) — family_assigned: dienelactone hydrolase family protein Rv2767c (Rv2767c) — family_assigned: hypothetical protein Rv2771c (Rv2771c) — family_assigned: flavodoxin family protein Rv2772c (Rv2772c) — family_assigned: hypothetical protein dapB (Rv2773c) — requalified: 4-hydroxy-tetrahydrodipicolinate reductase Rv2774c (Rv2774c) — dark: hypothetical protein Rv2777c (Rv2777c) — requalified: metal-dependent hydrolase Rv2778c (Rv2778c) — family_assigned: SRPBCC family protein ald (Rv2780) — requalified: alanine dehydrogenase Rv2781c (Rv2781c) — requalified: nitronate monooxygenase pepR (Rv2782c) — family_assigned: pitrilysin family protein gpsI (Rv2783c) — requalified: polyribonucleotide nucleotidyltransferase lppU (Rv2784c) — dark: hypothetical protein Rv2787 (Rv2787) — family_assigned: AAA family ATPase sirR (Rv2788) — family_assigned: manganese-binding transcriptional regulator MntR fadE21 (Rv2789c) — family_assigned: acyl-CoA dehydrogenase family protein ltp1 (Rv2790c) — requalified: lipid-transfer protein truB (Rv2793c) — requalified: tRNA pseudouridine(55) synthase TruB pptT (Rv2794c) — requalified: 4'-phosphopantetheinyl transferase Rv2795c (Rv2795c) — requalified: metallophosphoesterase lppV (Rv2796c) — family_assigned: LppA family lipoprotein Rv2797c (Rv2797c) — family_assigned: alpha/beta hydrolase family protein Rv2798c (Rv2798c) — family_assigned: hypothetical protein Rv2800 (Rv2800) — family_assigned: CocE/NonD family hydrolase mazF9 (Rv2801c) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF9 Rv2802c (Rv2802c) — dark: DUF2293 domain-containing protein Rv2806 (Rv2806) — dark: hypothetical protein Rv2805 (Rv2805) — requalified: transposase Rv2808 (Rv2808) — requalified: hypothetical protein Rv2809 (Rv2809) — family_assigned: hypothetical protein Rv2811 (Rv2811) — family_assigned: hypothetical protein Rv2813 (Rv2813) — family_assigned: ExeA family protein cas2 (Rv2816c) — requalified: CRISPR-associated endonuclease Cas2 cas1 (Rv2817c) — requalified: CRISPR-associated endonuclease Cas1 csm5 (Rv2819c) — requalified: type III-A CRISPR-associated RAMP protein Csm5 csm4 (Rv2820c) — requalified: type III-A CRISPR-associated RAMP protein Csm4 csm3 (Rv2821c) — requalified: type III-A CRISPR-associated RAMP protein Csm3 csm2 (Rv2822c) — requalified: type III-A CRISPR-associated protein Csm2 cas10 (Rv2823c) — requalified: type III-A CRISPR-associated protein Cas10/Csm1 Rv2826c (Rv2826c) — family_assigned: nucleotidyl transferase AbiEii/AbiGii toxin family protein Rv2827c (Rv2827c) — family_assigned: type IV toxin-antitoxin system AbiEi family antitoxin Rv2828c (Rv2828c) — family_assigned: DUF1802 family protein vapC22 (Rv2829c) — family_assigned: PIN domain-containing protein vapB22 (Rv2830c) — family_assigned: type II toxin-antitoxin system prevent-host-death family ant echA16 (Rv2831) — requalified: enoyl-CoA hydratase ugpC (Rv2832c) — family_assigned: ABC transporter ATP-binding protein ugpB (Rv2833c) — family_assigned: ABC transporter substrate-binding protein ugpE (Rv2834c) — family_assigned: carbohydrate ABC transporter permease ugpA (Rv2835c) — family_assigned: sugar ABC transporter permease dinF (Rv2836c) — family_assigned: MATE family efflux transporter 3 021 kb 3 048 kb 3 074 kb 3 100 kb 3 127 kb 3 154 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.