MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 884 477–3 044 477 bp (160 000 bp)
+ strand − strand aroD (Rv2537c) — requalified: type II 3-dehydroquinate dehydratase aroB (Rv2538c) — requalified: 3-dehydroquinate synthase aroK (Rv2539c) — requalified: shikimate kinase AroK aroF (Rv2540c) — requalified: chorismate synthase Rv2542 (Rv2542) — family_assigned: alpha/beta hydrolase family protein lppA (Rv2543) — family_assigned: LppA family lipoprotein lppB (Rv2544) — family_assigned: LppA family lipoprotein vapB18 (Rv2545) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC18 (Rv2546) — family_assigned: PIN domain nuclease vapB19 (Rv2547) — family_assigned: CopG family transcriptional regulator vapC19 (Rv2548) — family_assigned: type II toxin-antitoxin system VapC family toxin vapC20 (Rv2549c) — requalified: type II toxin-antitoxin system toxin 23S rRNA-specific endon vapB20 (Rv2550c) — requalified: type II toxin-antitoxin system antitoxin VapB20 Rv2551c (Rv2551c) — family_assigned: A24 family peptidase aroE (Rv2552c) — requalified: shikimate dehydrogenase mltG (Rv2553c) — requalified: endolytic transglycosylase MltG ruvX (Rv2554c) — requalified: Holliday junction resolvase RuvX alaS (Rv2555c) — requalified: alanine--tRNA ligase Rv2556c (Rv2556c) — requalified: secondary thiamine-phosphate synthase enzyme YjbQ Rv2559c (Rv2559c) — requalified: replication-associated recombination protein A Rv2560 (Rv2560) — family_assigned: DUF2189 domain-containing protein Rv2563 (Rv2563) — family_assigned: ABC transporter permease glnQ (Rv2564) — family_assigned: ATP-binding cassette domain-containing protein Rv2565 (Rv2565) — family_assigned: patatin-like phospholipase family protein Rv2567 (Rv2567) — requalified: circularly permuted type 2 ATP-grasp protein Rv2568c (Rv2568c) — family_assigned: putative zinc-binding metallopeptidase Rv2569c (Rv2569c) — family_assigned: transglutaminase family protein Rv2570 (Rv2570) — family_assigned: MmcQ/YjbR family DNA-binding protein Rv2571c (Rv2571c) — family_assigned: aromatic acid exporter family protein aspS (Rv2572c) — requalified: aspartate--tRNA ligase Rv2574 (Rv2574) — family_assigned: SRPBCC family protein Rv2575 (Rv2575) — requalified: neutral zinc metallopeptidase Rv2576c (Rv2576c) — family_assigned: hypothetical protein Rv2577 (Rv2577) — family_assigned: metallophosphoesterase family protein Rv2578c (Rv2578c) — family_assigned: Rv2578c family radical SAM protein hisS (Rv2580c) — requalified: histidine--tRNA ligase Rv2581c (Rv2581c) — requalified: MBL fold metallo-hydrolase relA (Rv2583c) — family_assigned: RelA/SpoT family protein apt (Rv2584c) — requalified: adenine phosphoribosyltransferase Rv2585c (Rv2585c) — family_assigned: ABC transporter substrate-binding protein secF (Rv2586c) — family_assigned: protein translocase subunit SecF secD (Rv2587c) — family_assigned: protein translocase subunit SecD yajC (Rv2588c) — family_assigned: preprotein translocase subunit YajC gabT (Rv2589) — requalified: 4-aminobutyrate--2-oxoglutarate transaminase fadD9 (Rv2590) — requalified: carboxylic acid reductase ruvB (Rv2592c) — requalified: Holliday junction branch migration DNA helicase RuvB ruvA (Rv2593c) — requalified: Holliday junction branch migration protein RuvA ruvC (Rv2594c) — requalified: crossover junction endodeoxyribonuclease RuvC vapB40 (Rv2595) — family_assigned: AbrB/MazE/SpoVT family DNA-binding domain-containing protein vapC40 (Rv2596) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2597 (Rv2597) — dark: DUF4178 domain-containing protein Rv2598 (Rv2598) — family_assigned: DUF2617 family protein Rv2599 (Rv2599) — family_assigned: DUF4247 domain-containing protein vapC41 (Rv2602) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2603c (Rv2603c) — family_assigned: YebC/PmpR family DNA-binding transcriptional regulator snoP (Rv2604c) — family_assigned: pyridoxal 5'-phosphate synthase glutaminase subunit PdxT tesB2 (Rv2605c) — requalified: acyl-CoA thioesterase II snzP (Rv2606c) — family_assigned: pyridoxal 5'-phosphate synthase lyase subunit PdxS pdxH (Rv2607) — requalified: pyridoxamine 5'-phosphate oxidase Rv2609c (Rv2609c) — family_assigned: NUDIX domain-containing protein pimA (Rv2610c) — requalified: phosphatidyl-myo-inositol alpha-mannosyltransferase Rv2611c (Rv2611c) — requalified: phosphatidylinositol mannoside acyltransferase Rv2613c (Rv2613c) — requalified: ATP adenylyltransferase thrS (Rv2614c) — requalified: threonine--tRNA ligase Rv2616 (Rv2616) — family_assigned: DUF1990 family protein Rv2617c (Rv2617c) — family_assigned: DoxX family membrane protein Rv2619c (Rv2619c) — family_assigned: cupin domain-containing protein Rv2620c (Rv2620c) — dark: hypothetical protein Rv2621c (Rv2621c) — family_assigned: helix-turn-helix domain-containing protein Rv2622 (Rv2622) — family_assigned: methyltransferase domain-containing protein TB31.7 (Rv2623) — requalified: universal stress protein TB31.7 Rv2625c (Rv2625c) — family_assigned: site-2 protease family protein hrp1 (Rv2626c) — requalified: hypoxic response protein Hrp1 Rv2627c (Rv2627c) — family_assigned: alpha/beta hydrolase Rv2629 (Rv2629) — family_assigned: hypothetical protein Rv2630 (Rv2630) — requalified: archease Rv2632c (Rv2632c) — family_assigned: DUF1876 domain-containing protein Rv2633c (Rv2633c) — requalified: non-heme di-iron catalase Rv2635 (Rv2635) — requalified: hypothetical protein Rv2636 (Rv2636) — family_assigned: chloramphenicol phosphotransferase CPT family protein dedA (Rv2637) — family_assigned: DedA family protein Rv2638 (Rv2638) — requalified: anti-sigma factor antagonist Rv2639c (Rv2639c) — family_assigned: YnfA family protein Rv2640c (Rv2640c) — family_assigned: Rv2640c family ArsR-like transcriptional regulator cadI (Rv2641) — requalified: cadmium-induced metalloenzyme CadI Rv2642 (Rv2642) — family_assigned: metalloregulator ArsR/SmtB family transcription factor arsC (Rv2643) — family_assigned: ACR3 family arsenite efflux transporter Rv2645 (Rv2645) — family_assigned: hypothetical protein Rv2646 (Rv2646) — requalified: tyrosine-type recombinase/integrase Rv2650c (Rv2650c) — requalified: phage major capsid protein Rv2651c (Rv2651c) — family_assigned: HK97 family phage prohead protease Rv2653c (Rv2653c) — requalified: type II toxin-antitoxin system toxin Rv2654c (Rv2654c) — requalified: type II toxin-antitoxin system antitoxin Rv2655c (Rv2655c) — family_assigned: DUF3631 domain-containing protein Rv2656c (Rv2656c) — dark: DUF2742 domain-containing protein Rv2657c (Rv2657c) — family_assigned: helix-turn-helix domain-containing protein Rv2658c (Rv2658c) — family_assigned: hypothetical protein Rv2659c (Rv2659c) — requalified: tyrosine-type recombinase/integrase Rv2660c (Rv2660c) — dark: hypothetical protein Rv2661c (Rv2661c) — dark: hypothetical protein Rv2662 (Rv2662) — dark: hypothetical protein Rv2663 (Rv2663) — requalified: hypothetical protein Rv2664 (Rv2664) — family_assigned: hypothetical protein Rv2665 (Rv2665) — requalified: arginine RICH protein Rv2668 (Rv2668) — family_assigned: hypothetical protein Rv2669 (Rv2669) — requalified: N-acetyltransferase zapE (Rv2670c) — requalified: cell division protein ZapE ribD (Rv2671) — requalified: bifunctional diaminohydroxyphosphoribosylaminopyrimidine dea Rv2672 (Rv2672) — requalified: alpha/beta fold hydrolase aftC (Rv2673) — requalified: arabinofuranan 3-O-arabinosyltransferase msrB (Rv2674) — requalified: peptide-methionine (R)-S-oxide reductase MsrB Rv2675c (Rv2675c) — requalified: class I SAM-dependent methyltransferase hemQ (Rv2676c) — requalified: hydrogen peroxide-dependent heme synthase hemE (Rv2678c) — requalified: uroporphyrinogen decarboxylase echA15 (Rv2679) — family_assigned: enoyl-CoA hydratase/isomerase family protein Rv2680 (Rv2680) — dark: DUF3000 domain-containing protein Rv2681 (Rv2681) — requalified: ribonuclease D arsA (Rv2684) — family_assigned: ArsB/NhaD family transporter Rv2686c (Rv2686c) — family_assigned: fluoroquinolones efflux ABC transporter permease Rv2687c (Rv2687c) — family_assigned: fluoroquinolone transporter permease Rv2688c (Rv2688c) — family_assigned: ABC transporter ATP-binding protein Rv2689c (Rv2689c) — requalified: class I SAM-dependent RNA methyltransferase Rv2693c (Rv2693c) — dark: DUF3159 domain-containing protein Rv2694c (Rv2694c) — family_assigned: OB-fold nucleic acid binding domain-containing protein Rv2695 (Rv2695) — requalified: alpha/beta fold hydrolase Rv2696c (Rv2696c) — dark: DUF3710 domain-containing protein Rv2698 (Rv2698) — dark: DUF3093 domain-containing protein Rv2699c (Rv2699c) — dark: DUF4193 domain-containing protein cei (Rv2700) — requalified: envelope integrity protein Cei suhB (Rv2701c) — requalified: inositol-1-monophosphatase SuhB ppgK (Rv2702) — family_assigned: ROK family protein sigA (Rv2703) — requalified: RNA polymerase sigma factor Rv2704 (Rv2704) — family_assigned: RidA family protein Rv2705c (Rv2705c) — family_assigned: DUF952 domain-containing protein Rv2706c (Rv2706c) — dark: hypothetical protein Rv2707 (Rv2707) — family_assigned: YihY/virulence factor BrkB family protein Rv2709 (Rv2709) — dark: DUF3099 domain-containing protein 2 888 kb 2 915 kb 2 942 kb 2 968 kb 2 994 kb 3 021 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.