MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 665 903–1 825 903 bp (160 000 bp)
+ strand − strand ctpD (Rv1469) — requalified: cobalt-translocating P-type ATPase CtpD trxA (Rv1470) — family_assigned: thioredoxin family protein echA12 (Rv1472) — requalified: enoyl-CoA hydratase Rv1473 (Rv1473) — family_assigned: macrolide ABC transporter ATP-binding protein Rv1474c (Rv1474c) — family_assigned: helix-turn-helix domain-containing protein acn (Rv1475c) — requalified: iron-regulated aconitate hydratase Acn Rv1476 (Rv1476) — family_assigned: DUF6676 family protein ripA (Rv1477) — family_assigned: NlpC/P60 family peptidoglycan endopeptidase RipA ripB (Rv1478) — family_assigned: NlpC/P60 family peptidoglycan endopeptidase RipB Rv1480 (Rv1480) — family_assigned: DUF58 domain-containing protein Rv1481 (Rv1481) — family_assigned: VWA domain-containing protein Rv1482c (Rv1482c) — family_assigned: hypothetical protein fabG1 (Rv1483) — requalified: 3-oxoacyl-ACP reductase FabG1 inhA (Rv1484) — requalified: NADH-dependent enoyl-ACP reductase InhA hemZ (Rv1485) — requalified: ferrochelatase Rv1486c (Rv1486c) — family_assigned: hypothetical protein Rv1487 (Rv1487) — family_assigned: NfeD family protein Rv1488 (Rv1488) — family_assigned: SPFH domain-containing protein Rv1490 (Rv1490) — family_assigned: hypothetical protein Rv1491c (Rv1491c) — family_assigned: TVP38/TMEM64 family protein mutA (Rv1492) — family_assigned: methylmalonyl-CoA mutase small subunit mutB (Rv1493) — requalified: methylmalonyl-CoA mutase mazE4 (Rv1494) — requalified: type II toxin-antitoxin system antitoxin MazE4 mazF4 (Rv1495) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF4 meaB (Rv1496) — requalified: methylmalonyl Co-A mutase-associated GTPase MeaB lipL (Rv1497) — family_assigned: serine hydrolase domain-containing protein Rv1499 (Rv1499) — requalified: glycosyltransferase (part1) Rv1500 (Rv1500) — family_assigned: glycosyltransferase family 2 protein Rv1501 (Rv1501) — family_assigned: phytanoyl-CoA dioxygenase family protein Rv1502 (Rv1502) — family_assigned: hypothetical protein Rv1505c (Rv1505c) — requalified: acetyltransferase Rv1507c (Rv1507c) — family_assigned: WbqC family protein Rv1508c (Rv1508c) — family_assigned: glycosyltransferase 87 family protein Rv1509 (Rv1509) — family_assigned: methyltransferase domain-containing protein Rv1510 (Rv1510) — family_assigned: hypothetical protein gmdA (Rv1511) — requalified: GDP-mannose 4%2C6-dehydratase epiA (Rv1512) — requalified: GDP-L-fucose synthase Rv1513 (Rv1513) — family_assigned: FkbM family methyltransferase Rv1514c (Rv1514c) — family_assigned: glycosyltransferase family 2 protein Rv1515c (Rv1515c) — family_assigned: methyltransferase domain-containing protein Rv1516c (Rv1516c) — requalified: glycosyltransferase Rv1517 (Rv1517) — family_assigned: GAP family protein Rv1518 (Rv1518) — requalified: glycosyltransferase Rv1520 (Rv1520) — requalified: glycosyltransferase fadD25 (Rv1521) — requalified: fatty-acid--AMP ligase FAAL25/FadD25 mmpL12 (Rv1522c) — requalified: RND transporter MmpL12 Rv1523 (Rv1523) — requalified: class I SAM-dependent methyltransferase Rv1524 (Rv1524) — requalified: glycosyltransferase wbbL2 (Rv1525) — family_assigned: glycosyltransferase family 2 protein Rv1526c (Rv1526c) — requalified: glycosyltransferase pks5 (Rv1527c) — requalified: sulfolipid-1 biosynthesis phthioceranic/hydroxyphthioceranic pks5 papA4 (Rv1528c) — requalified: polyketide synthase fadD24 (Rv1529) — requalified: fatty-acid--AMP ligase FAAL24/FadD24 adh (Rv1530) — requalified: zinc-binding dehydrogenase Rv1531 (Rv1531) — family_assigned: carboxymuconolactone decarboxylase family protein Rv1532c (Rv1532c) — family_assigned: PaaI family thioesterase Rv1533 (Rv1533) — family_assigned: nitronate monooxygenase family protein Rv1534 (Rv1534) — family_assigned: TetR family transcriptional regulator Rv1535 (Rv1535) — family_assigned: Rv1535 family protein ileS (Rv1536) — requalified: isoleucine--tRNA ligase dinX (Rv1537) — requalified: DNA polymerase IV ansA (Rv1538c) — requalified: asparaginase lspA (Rv1539) — requalified: signal peptidase II Rv1540 (Rv1540) — requalified: RNA pseudouridine synthase lprI (Rv1541c) — family_assigned: MliC family protein glbN (Rv1542c) — requalified: group 1 truncated hemoglobin GlbN Rv1543 (Rv1543) — family_assigned: SDR family NAD(P)-dependent oxidoreductase Rv1544 (Rv1544) — family_assigned: SDR family oxidoreductase Rv1545 (Rv1545) — dark: hypothetical protein Rv1546 (Rv1546) — family_assigned: SRPBCC family protein dnaE1 (Rv1547) — family_assigned: DNA polymerase III subunit alpha plsB1 (Rv1551) — requalified: lysophospholipid acyltransferase frdA (Rv1552) — family_assigned: fumarate reductase (quinol) flavoprotein subunit frdB (Rv1553) — family_assigned: succinate dehydrogenase iron-sulfur subunit frdC (Rv1554) — family_assigned: fumarate reductase subunit C frdD (Rv1555) — family_assigned: fumarate reductase subunit FrdD Rv1556 (Rv1556) — family_assigned: TetR/AcrR family transcriptional regulator Rv1558 (Rv1558) — requalified: F420H(2)-dependent quinone reductase ilvA (Rv1559) — requalified: threonine ammonia-lyase vapC11 (Rv1561) — requalified: type II toxin-antitoxin system toxin ribonuclease VapC11 Rv1565c (Rv1565c) — family_assigned: acyltransferase family protein ripD (Rv1566c) — family_assigned: NlpC/P60 family peptidoglycan-binding protein RipD bioA (Rv1568) — requalified: adenosylmethionine--8-amino-7-oxononanoate transaminase bioD (Rv1570) — requalified: dethiobiotin synthase Rv1571 (Rv1571) — family_assigned: 2'-5' RNA ligase family protein Rv1573 (Rv1573) — dark: hypothetical protein Rv1576c (Rv1576c) — requalified: phage major capsid protein Rv1578c (Rv1578c) — family_assigned: phage terminase small subunit P27 family est12 (Rv1579c) — requalified: hypothetical protein Rv1580c (Rv1580c) — family_assigned: hypothetical protein Rv1581c (Rv1581c) — dark: hypothetical protein Rv1582c (Rv1582c) — family_assigned: phage/plasmid primase%2C P4 family Rv1583c (Rv1583c) — dark: DUF2742 domain-containing protein Rv1584c (Rv1584c) — family_assigned: hypothetical protein Rv1585c (Rv1585c) — family_assigned: hypothetical protein Rv1586c (Rv1586c) — family_assigned: recombinase family protein bioB (Rv1589) — requalified: biotin synthase BioB Rv1590 (Rv1590) — family_assigned: hypothetical protein Rv1591 (Rv1591) — dark: DUF2567 domain-containing protein Rv1592c (Rv1592c) — family_assigned: lipase family protein Rv1593c (Rv1593c) — family_assigned: NUDIX domain-containing protein nadB (Rv1595) — requalified: L-aspartate oxidase nadC (Rv1596) — requalified: carboxylating nicotinate-nucleotide diphosphorylase Rv1597 (Rv1597) — family_assigned: methyltransferase domain-containing protein Rv1598c (Rv1598c) — family_assigned: nitroreductase family deazaflavin-dependent oxidoreductase hisD (Rv1599) — requalified: histidinol dehydrogenase hisB (Rv1601) — requalified: imidazoleglycerol-phosphate dehydratase HisB hisH (Rv1602) — family_assigned: imidazole glycerol phosphate synthase subunit HisH hisA (Rv1603) — requalified: bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino) impA (Rv1604) — family_assigned: inositol monophosphatase family protein hisF (Rv1605) — family_assigned: imidazole glycerol phosphate synthase subunit HisF hisI (Rv1606) — requalified: phosphoribosyl-AMP cyclohydrolase chaA (Rv1607) — requalified: calcium:proton antiporter bcpB (Rv1608c) — requalified: peroxiredoxin BcpB trpE (Rv1609) — requalified: anthranilate synthase component I Rv1610 (Rv1610) — family_assigned: TIGR02234 family membrane protein trpC (Rv1611) — requalified: indole-3-glycerol phosphate synthase TrpC trpA (Rv1613) — family_assigned: tryptophan synthase subunit alpha lgt (Rv1614) — requalified: prolipoprotein diacylglyceryl transferase 1 670 kb 1 696 kb 1 722 kb 1 749 kb 1 776 kb 1 802 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.