MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 715 454–875 454 bp (160 000 bp)
+ strand − strand galK (Rv0620) — requalified: galactokinase Rv0622 (Rv0622) — dark: DUF732 domain-containing protein vapB30 (Rv0623) — requalified: type II toxin-antitoxin system antitoxin VapB30 vapC30 (Rv0624) — requalified: type II toxin-antitoxin system toxin ribonuclease C30 Rv0625c (Rv0625c) — family_assigned: TVP38/TMEM64 family protein vapB5 (Rv0626) — family_assigned: type II toxin-antitoxin system Phd/YefM family antitoxin vapC5 (Rv0627) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv0628c (Rv0628c) — family_assigned: FIST N-terminal domain-containing protein recD (Rv0629c) — family_assigned: exodeoxyribonuclease V subunit alpha recB (Rv0630c) — family_assigned: exodeoxyribonuclease V subunit beta recC (Rv0631c) — family_assigned: exodeoxyribonuclease V subunit gamma echA3 (Rv0632c) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0633c (Rv0633c) — family_assigned: hypothetical protein Rv0634c (Rv0634c) — requalified: MBL fold metallo-hydrolase hadA (Rv0635) — family_assigned: (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadB (Rv0636) — family_assigned: (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadC (Rv0637) — family_assigned: (3R)-hydroxyacyl-ACP dehydratase subunit HadC nusG (Rv0639) — requalified: transcription termination/antitermination protein NusG rplK (Rv0640) — requalified: 50S ribosomal protein L11 rplA (Rv0641) — requalified: 50S ribosomal protein L1 mmaA4 (Rv0642c) — requalified: hydroxymycolate synthase MmaA4 mmaA3 (Rv0643c) — requalified: methoxy mycolic acid synthase MmaA3 mmaA2 (Rv0644c) — requalified: cyclopropane mycolic acid synthase MmaA2 mmaA1 (Rv0645c) — requalified: mycolic acid methyltransferase MmaA1 lipG (Rv0646c) — requalified: lipase/esterase LipG Rv0650 (Rv0650) — family_assigned: ROK family protein rplJ (Rv0651) — requalified: 50S ribosomal protein L10 rplL (Rv0652) — requalified: 50S ribosomal protein L7/L12 Rv0653c (Rv0653c) — family_assigned: TetR/AcrR family transcriptional regulator Rv0654 (Rv0654) — requalified: carotenoid cleavage oxygenase vapC6 (Rv0656c) — requalified: ribonuclease VapC6 vapB6 (Rv0657c) — family_assigned: type II toxin-antitoxin system VapB family antitoxin Rv0658c (Rv0658c) — family_assigned: CPBP family intramembrane glutamic endopeptidase mazF2 (Rv0659c) — family_assigned: type II toxin-antitoxin system PemK/MazF family toxin mazE2 (Rv0660c) — family_assigned: ribbon-helix-helix protein%2C CopG family vapC7 (Rv0661c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB7 (Rv0662c) — requalified: antitoxin atsD (Rv0663) — requalified: arylsulfatase AtsD vapC8 (Rv0665) — family_assigned: PIN domain-containing protein Rv0666 (Rv0666) — dark: hypothetical protein rpoB (Rv0667) — family_assigned: DNA-directed RNA polymerase subunit beta Rv0669c (Rv0669c) — requalified: neutral ceramidase end (Rv0670) — requalified: deoxyribonuclease IV lpqP (Rv0671) — family_assigned: PHB depolymerase family esterase fadE8 (Rv0672) — family_assigned: acyl-CoA dehydrogenase family protein echA4 (Rv0673) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0674 (Rv0674) — family_assigned: PaaX family transcriptional regulator C-terminal domain-cont mmpL5 (Rv0676c) — requalified: siderophore RND transporter MmpL5 mmpS5 (Rv0677c) — requalified: siderophore transporter accessory protein MmpS5 mmpR5 (Rv0678) — family_assigned: siderophore transport transcriptional regulator MmpR5 Rv0679c (Rv0679c) — family_assigned: DUF3060 domain-containing protein Rv0680c (Rv0680c) — dark: DUF3060 domain-containing protein Rv0681 (Rv0681) — family_assigned: TetR/AcrR family transcriptional regulator rpsL (Rv0682) — requalified: 30S ribosomal protein S12 Rv0686 (Rv0686) — family_assigned: SHOCT domain-containing protein Rv0687 (Rv0687) — family_assigned: Rv0687 family mycofactocin-dependent SDR oxidoreductase Rv0688 (Rv0688) — requalified: FAD/NAD(P)-binding oxidoreductase Rv0690c (Rv0690c) — family_assigned: DUF2332 domain-containing protein mftR (Rv0691c) — family_assigned: mycofactocin system transcriptional regulator mftB (Rv0692) — requalified: mycofactocin biosynthesis chaperone MftB mftC (Rv0693) — requalified: mycofactocin radical SAM maturase mftD (Rv0694) — requalified: pre-mycofactocin synthase MftD mftE (Rv0695) — requalified: mycofactocin biosynthesis peptidyl-dipeptidase MftE mftF (Rv0696) — requalified: mycofactocin biosynthesis glycosyltransferase MftF mftG (Rv0697) — family_assigned: mycofactocin system GMC family oxidoreductase MftG Rv0699 (Rv0699) — dark: hypothetical protein rplC (Rv0701) — requalified: 50S ribosomal protein L3 rplD (Rv0702) — requalified: 50S ribosomal protein L4 rplW (Rv0703) — requalified: 50S ribosomal protein L23 rplB (Rv0704) — requalified: 50S ribosomal protein L2 rpsS (Rv0705) — requalified: 30S ribosomal protein S19 rplV (Rv0706) — requalified: 50S ribosomal protein L22 rpsC (Rv0707) — requalified: 30S ribosomal protein S3 rplP (Rv0708) — requalified: 50S ribosomal protein L16 rpmC (Rv0709) — requalified: 50S ribosomal protein L29 rpsQ (Rv0710) — requalified: 30S ribosomal protein S17 atsA (Rv0711) — requalified: arylsulfatase AtsA Rv0712 (Rv0712) — family_assigned: formylglycine-generating enzyme family protein Rv0713 (Rv0713) — dark: DUF4436 domain-containing protein rplX (Rv0715) — requalified: 50S ribosomal protein L24 rplE (Rv0716) — requalified: 50S ribosomal protein L5 rplR (Rv0720) — requalified: 50S ribosomal protein L18 rpsE (Rv0721) — requalified: 30S ribosomal protein S5 rpmD (Rv0722) — requalified: 50S ribosomal protein L30 rplO (Rv0723) — requalified: 50S ribosomal protein L15 Rv0726c (Rv0726c) — requalified: class I SAM-dependent methyltransferase fucA (Rv0727c) — requalified: L-fuculose-phosphate aldolase serA2 (Rv0728c) — requalified: D-3-phosphoglycerate dehydrogenase SerA xylB (Rv0729) — requalified: FGGY-family carbohydrate kinase Rv0731c (Rv0731c) — requalified: class I SAM-dependent methyltransferase secY (Rv0732) — family_assigned: preprotein translocase subunit SecY adk (Rv0733) — requalified: adenylate kinase sigL (Rv0735) — family_assigned: sigma-70 family RNA polymerase sigma factor SigL rslA (Rv0736) — requalified: anti-sigma-L factor RslA Rv0737 (Rv0737) — family_assigned: MarR family transcriptional regulator Rv0738 (Rv0738) — family_assigned: TIGR03086 family metal-binding protein Rv0740 (Rv0740) — dark: hypothetical protein Rv0743c (Rv0743c) — family_assigned: DUF6036 family nucleotidyltransferase Rv0744c (Rv0744c) — family_assigned: helix-turn-helix domain-containing protein vapB31 (Rv0748) — family_assigned: ribbon-helix-helix protein%2C CopG family vapC31 (Rv0749) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv0750 (Rv0750) — dark: hypothetical protein mmsB (Rv0751c) — requalified: 3-hydroxyisobutyrate dehydrogenase fadE9 (Rv0752c) — family_assigned: acyl-CoA dehydrogenase family protein mmsA (Rv0753c) — requalified: CoA-acylating methylmalonate-semialdehyde dehydrogenase Rv0756c (Rv0756c) — family_assigned: hypothetical protein phoP (Rv0757) — requalified: two-component system response regulator PhoP phoR (Rv0758) — requalified: sensory box histidine kinase PhoR Rv0760c (Rv0760c) — family_assigned: ketosteroid isomerase family protein Rv0762c (Rv0762c) — family_assigned: nuclear transport factor 2 family protein Rv0763c (Rv0763c) — requalified: ferredoxin cyp51 (Rv0764c) — requalified: lanosterol 14-alpha demethylase Rv0765c (Rv0765c) — family_assigned: SDR family oxidoreductase cyp123 (Rv0766c) — requalified: cytochrome P450 Rv0767c (Rv0767c) — family_assigned: TetR/AcrR family transcriptional regulator aldA (Rv0768) — requalified: aldehyde dehydrogenase Rv0769 (Rv0769) — family_assigned: SDR family oxidoreductase Rv0770 (Rv0770) — requalified: NAD(P)-dependent oxidoreductase Rv0771 (Rv0771) — family_assigned: carboxymuconolactone decarboxylase family protein purD (Rv0772) — requalified: phosphoribosylamine--glycine ligase Rv0774c (Rv0774c) — requalified: iron-stress inducible esterase Rv0775 (Rv0775) — family_assigned: TetR/AcrR family transcriptional regulator Rv0776c (Rv0776c) — family_assigned: DUF429 domain-containing protein purB (Rv0777) — requalified: adenylosuccinate lyase 716 kb 742 kb 768 kb 795 kb 822 kb 848 kb 874 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.