MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 834 611–2 994 611 bp (160 000 bp)
+ strand − strand bkdA (Rv2497c) — family_assigned: pyruvate dehydrogenase (acetyl-transferring) E1 component su citE (Rv2498c) — family_assigned: citrate (pro-3S)-lyase subunit beta Rv2499c (Rv2499c) — family_assigned: MaoC family dehydratase fadE19 (Rv2500c) — family_assigned: acyl-CoA dehydrogenase family protein accA1 (Rv2501c) — family_assigned: acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alph accD1 (Rv2502c) — family_assigned: acetyl-/propionyl-CoA carboxylase subunit beta scoB (Rv2503c) — family_assigned: succinyl-CoA--3-ketoacid CoA transferase subunit B scoA (Rv2504c) — family_assigned: succinyl-CoA--3-ketoacid CoA transferase subunit A fadD35 (Rv2505c) — family_assigned: AMP-binding protein Rv2506 (Rv2506) — family_assigned: TetR/AcrR family transcriptional regulator Rv2507 (Rv2507) — family_assigned: MmpS family transport accessory protein Rv2508c (Rv2508c) — requalified: MFS transporter cmrA (Rv2509) — requalified: mycolate reductase Rv2510c (Rv2510c) — family_assigned: DUF853 domain-containing protein orn (Rv2511) — requalified: oligoribonuclease Rv2513 (Rv2513) — dark: hypothetical protein Rv2514c (Rv2514c) — family_assigned: DUF4411 family protein Rv2515c (Rv2515c) — family_assigned: XRE family transcriptional regulator Rv2516c (Rv2516c) — dark: hypothetical protein Rv2517c (Rv2517c) — dark: hypothetical protein ldtB (Rv2518c) — requalified: L%2CD-transpeptidase LdtMt2 Rv2520c (Rv2520c) — dark: DUF3618 domain-containing protein bcp (Rv2521) — requalified: thioredoxin-dependent thiol peroxidase Rv2522c (Rv2522c) — requalified: dipeptidase acpS (Rv2523c) — requalified: holo-ACP synthase fas (Rv2524c) — requalified: fatty acid synthase fas Rv2525c (Rv2525c) — family_assigned: DUF1906 domain-containing protein vapB17 (Rv2526) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC17 (Rv2527) — family_assigned: PIN domain-containing protein mrr (Rv2528c) — requalified: restriction endonuclease vapC39 (Rv2530c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2532c (Rv2532c) — requalified: antitermination protein NusB nusB (Rv2533c) — requalified: transcription antitermination factor NusB pepQ (Rv2535c) — family_assigned: Xaa-Pro peptidase family protein Rv2536 (Rv2536) — family_assigned: B-4DMT family transporter aroD (Rv2537c) — requalified: type II 3-dehydroquinate dehydratase aroB (Rv2538c) — requalified: 3-dehydroquinate synthase aroK (Rv2539c) — requalified: shikimate kinase AroK aroF (Rv2540c) — requalified: chorismate synthase Rv2542 (Rv2542) — family_assigned: alpha/beta hydrolase family protein lppA (Rv2543) — family_assigned: LppA family lipoprotein lppB (Rv2544) — family_assigned: LppA family lipoprotein vapB18 (Rv2545) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC18 (Rv2546) — family_assigned: PIN domain nuclease vapB19 (Rv2547) — family_assigned: CopG family transcriptional regulator vapC19 (Rv2548) — family_assigned: type II toxin-antitoxin system VapC family toxin vapC20 (Rv2549c) — requalified: type II toxin-antitoxin system toxin 23S rRNA-specific endon vapB20 (Rv2550c) — requalified: type II toxin-antitoxin system antitoxin VapB20 Rv2551c (Rv2551c) — family_assigned: A24 family peptidase aroE (Rv2552c) — requalified: shikimate dehydrogenase mltG (Rv2553c) — requalified: endolytic transglycosylase MltG ruvX (Rv2554c) — requalified: Holliday junction resolvase RuvX alaS (Rv2555c) — requalified: alanine--tRNA ligase Rv2556c (Rv2556c) — requalified: secondary thiamine-phosphate synthase enzyme YjbQ Rv2559c (Rv2559c) — requalified: replication-associated recombination protein A Rv2560 (Rv2560) — family_assigned: DUF2189 domain-containing protein Rv2563 (Rv2563) — family_assigned: ABC transporter permease glnQ (Rv2564) — family_assigned: ATP-binding cassette domain-containing protein Rv2565 (Rv2565) — family_assigned: patatin-like phospholipase family protein Rv2567 (Rv2567) — requalified: circularly permuted type 2 ATP-grasp protein Rv2568c (Rv2568c) — family_assigned: putative zinc-binding metallopeptidase Rv2569c (Rv2569c) — family_assigned: transglutaminase family protein Rv2570 (Rv2570) — family_assigned: MmcQ/YjbR family DNA-binding protein Rv2571c (Rv2571c) — family_assigned: aromatic acid exporter family protein aspS (Rv2572c) — requalified: aspartate--tRNA ligase Rv2574 (Rv2574) — family_assigned: SRPBCC family protein Rv2575 (Rv2575) — requalified: neutral zinc metallopeptidase Rv2576c (Rv2576c) — family_assigned: hypothetical protein Rv2577 (Rv2577) — family_assigned: metallophosphoesterase family protein Rv2578c (Rv2578c) — family_assigned: Rv2578c family radical SAM protein hisS (Rv2580c) — requalified: histidine--tRNA ligase Rv2581c (Rv2581c) — requalified: MBL fold metallo-hydrolase relA (Rv2583c) — family_assigned: RelA/SpoT family protein apt (Rv2584c) — requalified: adenine phosphoribosyltransferase Rv2585c (Rv2585c) — family_assigned: ABC transporter substrate-binding protein secF (Rv2586c) — family_assigned: protein translocase subunit SecF secD (Rv2587c) — family_assigned: protein translocase subunit SecD yajC (Rv2588c) — family_assigned: preprotein translocase subunit YajC gabT (Rv2589) — requalified: 4-aminobutyrate--2-oxoglutarate transaminase fadD9 (Rv2590) — requalified: carboxylic acid reductase ruvB (Rv2592c) — requalified: Holliday junction branch migration DNA helicase RuvB ruvA (Rv2593c) — requalified: Holliday junction branch migration protein RuvA ruvC (Rv2594c) — requalified: crossover junction endodeoxyribonuclease RuvC vapB40 (Rv2595) — family_assigned: AbrB/MazE/SpoVT family DNA-binding domain-containing protein vapC40 (Rv2596) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2597 (Rv2597) — dark: DUF4178 domain-containing protein Rv2598 (Rv2598) — family_assigned: DUF2617 family protein Rv2599 (Rv2599) — family_assigned: DUF4247 domain-containing protein vapC41 (Rv2602) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2603c (Rv2603c) — family_assigned: YebC/PmpR family DNA-binding transcriptional regulator snoP (Rv2604c) — family_assigned: pyridoxal 5'-phosphate synthase glutaminase subunit PdxT tesB2 (Rv2605c) — requalified: acyl-CoA thioesterase II snzP (Rv2606c) — family_assigned: pyridoxal 5'-phosphate synthase lyase subunit PdxS pdxH (Rv2607) — requalified: pyridoxamine 5'-phosphate oxidase Rv2609c (Rv2609c) — family_assigned: NUDIX domain-containing protein pimA (Rv2610c) — requalified: phosphatidyl-myo-inositol alpha-mannosyltransferase Rv2611c (Rv2611c) — requalified: phosphatidylinositol mannoside acyltransferase Rv2613c (Rv2613c) — requalified: ATP adenylyltransferase thrS (Rv2614c) — requalified: threonine--tRNA ligase Rv2616 (Rv2616) — family_assigned: DUF1990 family protein Rv2617c (Rv2617c) — family_assigned: DoxX family membrane protein Rv2619c (Rv2619c) — family_assigned: cupin domain-containing protein Rv2620c (Rv2620c) — dark: hypothetical protein Rv2621c (Rv2621c) — family_assigned: helix-turn-helix domain-containing protein Rv2622 (Rv2622) — family_assigned: methyltransferase domain-containing protein TB31.7 (Rv2623) — requalified: universal stress protein TB31.7 Rv2625c (Rv2625c) — family_assigned: site-2 protease family protein hrp1 (Rv2626c) — requalified: hypoxic response protein Hrp1 Rv2627c (Rv2627c) — family_assigned: alpha/beta hydrolase Rv2629 (Rv2629) — family_assigned: hypothetical protein Rv2630 (Rv2630) — requalified: archease Rv2632c (Rv2632c) — family_assigned: DUF1876 domain-containing protein Rv2633c (Rv2633c) — requalified: non-heme di-iron catalase Rv2635 (Rv2635) — requalified: hypothetical protein Rv2636 (Rv2636) — family_assigned: chloramphenicol phosphotransferase CPT family protein dedA (Rv2637) — family_assigned: DedA family protein Rv2638 (Rv2638) — requalified: anti-sigma factor antagonist Rv2639c (Rv2639c) — family_assigned: YnfA family protein Rv2640c (Rv2640c) — family_assigned: Rv2640c family ArsR-like transcriptional regulator cadI (Rv2641) — requalified: cadmium-induced metalloenzyme CadI Rv2642 (Rv2642) — family_assigned: metalloregulator ArsR/SmtB family transcription factor arsC (Rv2643) — family_assigned: ACR3 family arsenite efflux transporter Rv2645 (Rv2645) — family_assigned: hypothetical protein Rv2646 (Rv2646) — requalified: tyrosine-type recombinase/integrase 2 836 kb 2 862 kb 2 888 kb 2 915 kb 2 942 kb 2 968 kb 2 994 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.