MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 731 743–1 891 743 bp (160 000 bp)
+ strand − strand Rv1526c (Rv1526c) — requalified: glycosyltransferase pks5 (Rv1527c) — requalified: sulfolipid-1 biosynthesis phthioceranic/hydroxyphthioceranic pks5 papA4 (Rv1528c) — requalified: polyketide synthase fadD24 (Rv1529) — requalified: fatty-acid--AMP ligase FAAL24/FadD24 adh (Rv1530) — requalified: zinc-binding dehydrogenase Rv1531 (Rv1531) — family_assigned: carboxymuconolactone decarboxylase family protein Rv1532c (Rv1532c) — family_assigned: PaaI family thioesterase Rv1533 (Rv1533) — family_assigned: nitronate monooxygenase family protein Rv1534 (Rv1534) — family_assigned: TetR family transcriptional regulator Rv1535 (Rv1535) — family_assigned: Rv1535 family protein ileS (Rv1536) — requalified: isoleucine--tRNA ligase dinX (Rv1537) — requalified: DNA polymerase IV ansA (Rv1538c) — requalified: asparaginase lspA (Rv1539) — requalified: signal peptidase II Rv1540 (Rv1540) — requalified: RNA pseudouridine synthase lprI (Rv1541c) — family_assigned: MliC family protein glbN (Rv1542c) — requalified: group 1 truncated hemoglobin GlbN Rv1543 (Rv1543) — family_assigned: SDR family NAD(P)-dependent oxidoreductase Rv1544 (Rv1544) — family_assigned: SDR family oxidoreductase Rv1545 (Rv1545) — dark: hypothetical protein Rv1546 (Rv1546) — family_assigned: SRPBCC family protein dnaE1 (Rv1547) — family_assigned: DNA polymerase III subunit alpha plsB1 (Rv1551) — requalified: lysophospholipid acyltransferase frdA (Rv1552) — family_assigned: fumarate reductase (quinol) flavoprotein subunit frdB (Rv1553) — family_assigned: succinate dehydrogenase iron-sulfur subunit frdC (Rv1554) — family_assigned: fumarate reductase subunit C frdD (Rv1555) — family_assigned: fumarate reductase subunit FrdD Rv1556 (Rv1556) — family_assigned: TetR/AcrR family transcriptional regulator Rv1558 (Rv1558) — requalified: F420H(2)-dependent quinone reductase ilvA (Rv1559) — requalified: threonine ammonia-lyase vapC11 (Rv1561) — requalified: type II toxin-antitoxin system toxin ribonuclease VapC11 Rv1565c (Rv1565c) — family_assigned: acyltransferase family protein ripD (Rv1566c) — family_assigned: NlpC/P60 family peptidoglycan-binding protein RipD bioA (Rv1568) — requalified: adenosylmethionine--8-amino-7-oxononanoate transaminase bioD (Rv1570) — requalified: dethiobiotin synthase Rv1571 (Rv1571) — family_assigned: 2'-5' RNA ligase family protein Rv1573 (Rv1573) — dark: hypothetical protein Rv1576c (Rv1576c) — requalified: phage major capsid protein Rv1578c (Rv1578c) — family_assigned: phage terminase small subunit P27 family est12 (Rv1579c) — requalified: hypothetical protein Rv1580c (Rv1580c) — family_assigned: hypothetical protein Rv1581c (Rv1581c) — dark: hypothetical protein Rv1582c (Rv1582c) — family_assigned: phage/plasmid primase%2C P4 family Rv1583c (Rv1583c) — dark: DUF2742 domain-containing protein Rv1584c (Rv1584c) — family_assigned: hypothetical protein Rv1585c (Rv1585c) — family_assigned: hypothetical protein Rv1586c (Rv1586c) — family_assigned: recombinase family protein bioB (Rv1589) — requalified: biotin synthase BioB Rv1590 (Rv1590) — family_assigned: hypothetical protein Rv1591 (Rv1591) — dark: DUF2567 domain-containing protein Rv1592c (Rv1592c) — family_assigned: lipase family protein Rv1593c (Rv1593c) — family_assigned: NUDIX domain-containing protein nadB (Rv1595) — requalified: L-aspartate oxidase nadC (Rv1596) — requalified: carboxylating nicotinate-nucleotide diphosphorylase Rv1597 (Rv1597) — family_assigned: methyltransferase domain-containing protein Rv1598c (Rv1598c) — family_assigned: nitroreductase family deazaflavin-dependent oxidoreductase hisD (Rv1599) — requalified: histidinol dehydrogenase hisB (Rv1601) — requalified: imidazoleglycerol-phosphate dehydratase HisB hisH (Rv1602) — family_assigned: imidazole glycerol phosphate synthase subunit HisH hisA (Rv1603) — requalified: bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino) impA (Rv1604) — family_assigned: inositol monophosphatase family protein hisF (Rv1605) — family_assigned: imidazole glycerol phosphate synthase subunit HisF hisI (Rv1606) — requalified: phosphoribosyl-AMP cyclohydrolase chaA (Rv1607) — requalified: calcium:proton antiporter bcpB (Rv1608c) — requalified: peroxiredoxin BcpB trpE (Rv1609) — requalified: anthranilate synthase component I Rv1610 (Rv1610) — family_assigned: TIGR02234 family membrane protein trpC (Rv1611) — requalified: indole-3-glycerol phosphate synthase TrpC trpA (Rv1613) — family_assigned: tryptophan synthase subunit alpha lgt (Rv1614) — requalified: prolipoprotein diacylglyceryl transferase Rv1615 (Rv1615) — family_assigned: TM2 domain-containing protein Rv1616 (Rv1616) — family_assigned: DUF2752 domain-containing protein pykA (Rv1617) — requalified: pyruvate kinase tesB1 (Rv1618) — requalified: acyl-CoA thioesterase II Rv1619 (Rv1619) — requalified: bifunctional lysylphosphatidylglycerol flippase/synthetase M cydC (Rv1620c) — family_assigned: thiol reductant ABC exporter subunit CydC cydB (Rv1622c) — family_assigned: cytochrome d ubiquinol oxidase subunit II Rv1624c (Rv1624c) — family_assigned: HdeD family acid-resistance protein cya (Rv1625c) — requalified: adenylate cyclase Rv1626 (Rv1626) — family_assigned: ANTAR domain-containing response regulator Rv1627c (Rv1627c) — requalified: lipid-transfer protein Rv1628c (Rv1628c) — family_assigned: Zn-ribbon domain-containing OB-fold protein polA (Rv1629) — requalified: DNA polymerase I rpsA (Rv1630) — requalified: 30S ribosomal protein S1 coaE (Rv1631) — requalified: dephospho-CoA kinase Rv1632c (Rv1632c) — family_assigned: DUF402 domain-containing protein Rv1634 (Rv1634) — requalified: MFS transporter Rv1635c (Rv1635c) — family_assigned: glycosyltransferase family 39 protein TB15.3 (Rv1636) — requalified: universal stress protein uvrA (Rv1638) — family_assigned: excinuclease ABC subunit UvrA Rv1639c (Rv1639c) — family_assigned: alpha/beta hydrolase family protein infC (Rv1641) — requalified: translation initiation factor IF-3 rplT (Rv1643) — requalified: 50S ribosomal protein L20 tsnR (Rv1644) — requalified: RNA methyltransferase Rv1645c (Rv1645c) — family_assigned: oxygenase MpaB family protein Rv1648 (Rv1648) — family_assigned: rhomboid-like protein pheT (Rv1650) — family_assigned: phenylalanine--tRNA ligase subunit beta argC (Rv1652) — requalified: N-acetyl-gamma-glutamyl-phosphate reductase argJ (Rv1653) — requalified: bifunctional glutamate N-acetyltransferase/amino-acid acetyl argB (Rv1654) — requalified: acetylglutamate kinase argD (Rv1655) — requalified: acetylornithine transaminase argF (Rv1656) — requalified: ornithine carbamoyltransferase argR (Rv1657) — requalified: arginine repressor argG (Rv1658) — requalified: argininosuccinate synthase argH (Rv1659) — requalified: argininosuccinate lyase pks10 (Rv1660) — requalified: type III polyketide synthase pks7 (Rv1661) — requalified: type I polyketide synthase pks7 1 749 kb 1 776 kb 1 802 kb 1 828 kb 1 855 kb 1 882 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.