MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 139 384–299 384 bp (160 000 bp)
+ strand − strand hddA (Rv0115) — requalified: D-alpha-D-heptose-7-phosphate kinase HddA ldtA (Rv0116c) — requalified: L%2CD-transpeptidase LdtMt1 oxyS (Rv0117) — family_assigned: LysR family transcriptional regulator OxyS oxcA (Rv0118c) — requalified: oxalyl-CoA decarboxylase fadD7 (Rv0119) — family_assigned: FadD7 family fatty acid--CoA ligase fusA2 (Rv0120c) — family_assigned: elongation factor G-like protein EF-G2 Rv0121c (Rv0121c) — family_assigned: TIGR03668 family PPOX class F420-dependent oxidoreductase Rv0122 (Rv0122) — family_assigned: hypothetical protein Rv0123 (Rv0123) — family_assigned: DNA-binding protein pepA (Rv0125) — family_assigned: S1C family serine protease treS (Rv0126) — requalified: maltose alpha-D-glucosyltransferase mak (Rv0127) — requalified: maltokinase Rv0128 (Rv0128) — family_assigned: YoaK family protein htdZ (Rv0130) — requalified: 3-hydroxyacyl-thioester dehydratase HtdZ fgd2 (Rv0132c) — requalified: F420-dependent hydroxymycolic acid dehydrogenase Rv0133 (Rv0133) — family_assigned: GNAT family N-acetyltransferase ephF (Rv0134) — family_assigned: alpha/beta hydrolase Rv0135c (Rv0135c) — family_assigned: helix-turn-helix domain-containing protein cyp138 (Rv0136) — requalified: cytochrome P450 msrA (Rv0137c) — requalified: peptide-methionine (S)-S-oxide reductase MsrA Rv0138 (Rv0138) — family_assigned: nuclear transport factor 2 family protein Rv0139 (Rv0139) — family_assigned: NAD-dependent epimerase/dehydratase family protein Rv0140 (Rv0140) — family_assigned: DUF427 domain-containing protein Rv0141c (Rv0141c) — family_assigned: nuclear transport factor 2 family protein Rv0142 (Rv0142) — requalified: DNA-3-methyladenine glycosylase Rv0143c (Rv0143c) — requalified: chloride channel protein Rv0145 (Rv0145) — requalified: class I SAM-dependent methyltransferase Rv0146 (Rv0146) — requalified: class I SAM-dependent methyltransferase Rv0148 (Rv0148) — family_assigned: SDR family oxidoreductase Rv0149 (Rv0149) — family_assigned: NADPH:quinone oxidoreductase family protein Rv0150c (Rv0150c) — dark: hypothetical protein ptbB (Rv0153c) — requalified: tyrosine-protein phosphatase PtbB fadE2 (Rv0154c) — requalified: acyl-CoA dehydrogenase pntAa (Rv0155) — family_assigned: Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha pntAb (Rv0156) — family_assigned: NAD(P) transhydrogenase subunit alpha pntB (Rv0157) — family_assigned: NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta Rv0158 (Rv0158) — family_assigned: TetR/AcrR family transcriptional regulator Rv0161 (Rv0161) — requalified: FAD-binding oxidoreductase Rv0163 (Rv0163) — family_assigned: thioesterase family protein fadD5 (Rv0166) — requalified: fatty-acid--CoA ligase FadD5 yrbE1A (Rv0167) — family_assigned: ABC transporter permease yrbE1B (Rv0168) — family_assigned: ABC transporter permease mce1B (Rv0170) — family_assigned: virulence factor Mce family protein mce1C (Rv0171) — family_assigned: MCE family protein mce1D (Rv0172) — family_assigned: virulence factor Mce family protein lprK (Rv0173) — family_assigned: virulence factor Mce family protein mce1F (Rv0174) — family_assigned: MCE family protein Rv0175 (Rv0175) — family_assigned: hypothetical protein Rv0176 (Rv0176) — family_assigned: RDD family protein Rv0178 (Rv0178) — requalified: Mce associated membrane protein lprO (Rv0179c) — family_assigned: phosphodiester glycosidase family protein Rv0180c (Rv0180c) — family_assigned: YhgE/Pip domain-containing protein Rv0181c (Rv0181c) — family_assigned: pirin family protein sigG (Rv0182c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigG Rv0183 (Rv0183) — requalified: monoacylglycerol lipase Rv0184 (Rv0184) — dark: DUF2786 domain-containing protein Rv0185 (Rv0185) — family_assigned: TIGR04338 family metallohydrolase Rv0187 (Rv0187) — requalified: O-methyltransferase Rv0188 (Rv0188) — requalified: SPW repeat protein ilvD (Rv0189c) — requalified: dihydroxy-acid dehydratase Rv0190 (Rv0190) — family_assigned: metal-sensitive transcriptional regulator Rv0191 (Rv0191) — family_assigned: Rv0191 family MFS efflux transporter Rv0193c (Rv0193c) — family_assigned: hypothetical protein Rv0194 (Rv0194) — family_assigned: ABC transporter ATP-binding protein Rv0195 (Rv0195) — requalified: response regulator transcription factor Rv0196 (Rv0196) — family_assigned: TetR/AcrR family transcriptional regulator zmp1 (Rv0198c) — requalified: zinc metalloprotease Zmp1 omamA (Rv0199) — requalified: hypothetical protein omamB (Rv0200) — requalified: hypothetical protein Rv0201c (Rv0201c) — family_assigned: XRE family transcriptional regulator mmpL11 (Rv0202c) — requalified: RND transporter MmpL11 Rv0203 (Rv0203) — requalified: hemophore Rv0204c (Rv0204c) — family_assigned: TIGR00374 family protein Rv0205 (Rv0205) — family_assigned: AI-2E family transporter mmpL3 (Rv0206c) — requalified: trehalose monomycolate RND transporter MmpL3 Rv0207c (Rv0207c) — family_assigned: NYN domain-containing protein trmB (Rv0208c) — requalified: tRNA (guanosine(46)-N7)-methyltransferase TrmB Rv0209 (Rv0209) — family_assigned: hypothetical protein Rv0210 (Rv0210) — family_assigned: hypothetical protein pckA (Rv0211) — requalified: phosphoenolpyruvate carboxykinase (GTP) nadR (Rv0212c) — requalified: nicotinamide-nucleotide adenylyltransferase Rv0216 (Rv0216) — family_assigned: MaoC family dehydratase lipW (Rv0217c) — family_assigned: alpha/beta hydrolase Rv0218 (Rv0218) — requalified: molybdopterin-dependent oxidoreductase Rv0219 (Rv0219) — dark: hypothetical protein lipC (Rv0220) — requalified: esterase LipC Rv0221 (Rv0221) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase echA1 (Rv0222) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0223c (Rv0223c) — requalified: aldehyde dehydrogenase Rv0224c (Rv0224c) — requalified: class I SAM-dependent methyltransferase Rv0225 (Rv0225) — family_assigned: glycosyltransferase family 4 protein mmpA (Rv0226c) — requalified: hypothetical protein Rv0228 (Rv0228) — requalified: acyltransferase Rv0229c (Rv0229c) — family_assigned: PIN domain nuclease php (Rv0230c) — requalified: phosphotriesterase-related protein fadE4 (Rv0231) — family_assigned: acyl-CoA dehydrogenase family protein Rv0232 (Rv0232) — family_assigned: TetR/AcrR family transcriptional regulator nrdB (Rv0233) — requalified: R2-like ligand-binding oxidase Rv0235c (Rv0235c) — family_assigned: lipase maturation factor family protein aftD (Rv0236c) — family_assigned: DUF3367 domain-containing protein aftD Rv0238 (Rv0238) — family_assigned: TetR/AcrR family transcriptional regulator vapB24 (Rv0239) — requalified: antitoxin vapC24 (Rv0240) — family_assigned: type II toxin-antitoxin system VapC family toxin htdX (Rv0241c) — requalified: 3-hydroxyacyl-thioester dehydratase HtdX fabG4 (Rv0242c) — requalified: 3-oxoacyl-ACP reductase fadA2 (Rv0243) — requalified: acetyl-CoA C-acetyltransferase fadE5 (Rv0244c) — requalified: acyl-CoA dehydrogenase Rv0245 (Rv0245) — family_assigned: flavin reductase family protein Rv0246 (Rv0246) — family_assigned: integral membrane protein Rv0247c (Rv0247c) — family_assigned: succinate dehydrogenase/fumarate reductase iron-sulfur subun Rv0248c (Rv0248c) — family_assigned: fumarate reductase/succinate dehydrogenase flavoprotein subu 159 kb 186 kb 212 kb 238 kb 265 kb 292 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.