MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 283 749–2 443 749 bp (160 000 bp)
+ strand − strand Rv2015c (Rv2015c) — requalified: HNH endonuclease signature motif containing protein Rv2016 (Rv2016) — dark: hypothetical protein Rv2017 (Rv2017) — family_assigned: ImmA/IrrE family metallo-endopeptidase Rv2018 (Rv2018) — family_assigned: DUF433 domain-containing protein Rv2019 (Rv2019) — family_assigned: hypothetical protein Rv2021c (Rv2021c) — family_assigned: XRE family transcriptional regulator Rv2022c (Rv2022c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2023c (Rv2023c) — dark: hypothetical protein Rv2025c (Rv2025c) — family_assigned: cation diffusion facilitator family transporter Rv2026c (Rv2026c) — requalified: universal stress protein dosT (Rv2027c) — requalified: two-component system sensor histidine kinase DosT Rv2028c (Rv2028c) — requalified: universal stress protein pfkB (Rv2029c) — family_assigned: 1-phosphofructokinase family hexose kinase Rv2030c (Rv2030c) — family_assigned: erythromycin esterase family protein hspX (Rv2031c) — requalified: alpha-crystallin HspX acg (Rv2032) — family_assigned: FMN-binding protein Acg Rv2033c (Rv2033c) — family_assigned: DUF3097 domain-containing protein Rv2034 (Rv2034) — family_assigned: metalloregulator ArsR/SmtB family transcription factor Rv2035 (Rv2035) — family_assigned: SRPBCC family protein Rv2036 (Rv2036) — family_assigned: maleylpyruvate isomerase family mycothiol-dependent enzyme Rv2037c (Rv2037c) — family_assigned: patatin-like phospholipase family protein ugpC (Rv2038c) — family_assigned: sn-glycerol-3-phosphate ABC transporter ATP-binding protein Rv2039c (Rv2039c) — family_assigned: carbohydrate ABC transporter permease Rv2040c (Rv2040c) — family_assigned: sugar ABC transporter permease Rv2041c (Rv2041c) — family_assigned: sugar ABC transporter substrate-binding protein Rv2042c (Rv2042c) — family_assigned: ketosteroid isomerase family protein pncA (Rv2043c) — requalified: pyrazinamidase PncA lppI (Rv2046) — family_assigned: hypothetical protein Rv2047c (Rv2047c) — family_assigned: sugar epimerase family protein pks12 (Rv2048c) — requalified: type I polyketide synthase pks12 rbpA (Rv2050) — family_assigned: RNA polymerase-binding protein RbpA ppm1 (Rv2051c) — requalified: apolipoprotein N-acyltransferase Rv2052c (Rv2052c) — requalified: amidohydrolase fxsA (Rv2053c) — family_assigned: FxsA family protein Rv2054 (Rv2054) — family_assigned: dienelactone hydrolase family protein rpsR2 (Rv2055c) — requalified: 30S ribosomal protein S18 rpsN2 (Rv2056c) — requalified: 30S ribosomal protein S14 rpmB2 (Rv2058c) — requalified: 50S ribosomal protein L28 Rv2061c (Rv2061c) — requalified: PPOX class F420-dependent oxidoreductase cobN (Rv2062c) — family_assigned: cobaltochelatase subunit CobN cobG (Rv2064) — requalified: precorrin-3B synthase cobH (Rv2065) — requalified: precorrin-8X methylmutase cobIJ (Rv2066) — requalified: precorrin-2 C(20)-methyltransferase Rv2067c (Rv2067c) — requalified: class I SAM-dependent methyltransferase sigC (Rv2069) — requalified: RNA polymerase sigma factor SigC cobK (Rv2070c) — requalified: cobalt-precorrin-6A reductase cobM (Rv2071c) — requalified: precorrin-4 C(11)-methyltransferase cobL (Rv2072c) — requalified: bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cob Rv2073c (Rv2073c) — family_assigned: SDR family NAD(P)-dependent oxidoreductase Rv2074 (Rv2074) — requalified: F420-dependent biliverdin reductase Rv2075c (Rv2075c) — family_assigned: hypothetical protein Rv2077c (Rv2077c) — dark: hypothetical protein Rv2078 (Rv2078) — family_assigned: DUF2563 family protein Rv2079 (Rv2079) — family_assigned: alpha/beta hydrolase lppJ (Rv2080) — family_assigned: hypothetical protein Rv2081c (Rv2081c) — dark: hypothetical protein Rv2082 (Rv2082) — dark: DUF5631 domain-containing protein Rv2083 (Rv2083) — dark: hypothetical protein Rv2084 (Rv2084) — dark: hypothetical protein pknJ (Rv2088) — requalified: serine/threonine protein kinase PknJ pepE (Rv2089c) — family_assigned: Xaa-Pro peptidase family protein Rv2091c (Rv2091c) — family_assigned: DUF4333 domain-containing protein helY (Rv2092c) — requalified: RNA helicase tatC (Rv2093c) — family_assigned: twin-arginine translocase subunit TatC tatA (Rv2094c) — family_assigned: Sec-independent protein translocase subunit TatA pafC (Rv2095c) — family_assigned: YafY family protein pafB (Rv2096c) — family_assigned: YafY family protein pafA (Rv2097c) — requalified: Pup--protein ligase helZ (Rv2101) — requalified: DEAD/DEAH box helicase vapC37 (Rv2103c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB37 (Rv2104c) — requalified: antitoxin prcA (Rv2109c) — family_assigned: proteasome subunit alpha prcB (Rv2110c) — family_assigned: proteasome subunit beta Rv2113 (Rv2113) — family_assigned: integral membrane protein Rv2114 (Rv2114) — dark: hypothetical protein mpa (Rv2115c) — requalified: proteasome ATPase lppK (Rv2116) — family_assigned: hypothetical protein Rv2117 (Rv2117) — family_assigned: DUF503 domain-containing protein trmI (Rv2118c) — requalified: tRNA (adenine(58)-N(1))-methyltransferase TrmI Rv2119 (Rv2119) — family_assigned: RecB family exonuclease Rv2120c (Rv2120c) — family_assigned: glycine zipper 2TM domain-containing protein hisG (Rv2121c) — requalified: ATP phosphoribosyltransferase metH (Rv2124c) — requalified: methionine synthase Rv2125 (Rv2125) — family_assigned: PAC2 family protein Rv2128 (Rv2128) — dark: hypothetical protein Rv2129c (Rv2129c) — family_assigned: SDR family oxidoreductase mshC (Rv2130c) — requalified: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyra cysQ (Rv2131c) — requalified: 3'(2')%2C5'-bisphosphate nucleotidase CysQ Rv2132 (Rv2132) — family_assigned: ribbon-helix-helix protein%2C CopG family Rv2133c (Rv2133c) — family_assigned: SCO1664 family protein Rv2135c (Rv2135c) — family_assigned: histidine phosphatase family protein Rv2136c (Rv2136c) — requalified: undecaprenyl-diphosphate phosphatase lppL (Rv2138) — family_assigned: hypothetical protein pyrD (Rv2139) — requalified: quinone-dependent dihydroorotate dehydrogenase TB18.6 (Rv2140c) — family_assigned: YbhB/YbcL family Raf kinase inhibitor-like protein parE2 (Rv2142c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2143 (Rv2143) — family_assigned: phosphoribosyltransferase family protein Rv2144c (Rv2144c) — dark: hypothetical protein wag31 (Rv2145c) — requalified: cell wall synthesis protein Wag31 Rv2146c (Rv2146c) — family_assigned: YggT family protein Rv2148c (Rv2148c) — family_assigned: YggS family pyridoxal phosphate-dependent enzyme ftsZ (Rv2150c) — requalified: cell division protein FtsZ ftsQ (Rv2151c) — requalified: cell division protein FtsQ murC (Rv2152c) — requalified: UDP-N-acetylmuramate--L-alanine ligase murG (Rv2153c) — requalified: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylgluc ftsW (Rv2154c) — family_assigned: putative lipid II flippase FtsW murD (Rv2155c) — requalified: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase 2 306 kb 2 332 kb 2 358 kb 2 385 kb 2 412 kb 2 438 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.