MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 363 043–2 523 043 bp (160 000 bp)
+ strand − strand Rv2078 (Rv2078) — family_assigned: DUF2563 family protein Rv2079 (Rv2079) — family_assigned: alpha/beta hydrolase lppJ (Rv2080) — family_assigned: hypothetical protein Rv2081c (Rv2081c) — dark: hypothetical protein Rv2082 (Rv2082) — dark: DUF5631 domain-containing protein Rv2083 (Rv2083) — dark: hypothetical protein Rv2084 (Rv2084) — dark: hypothetical protein pknJ (Rv2088) — requalified: serine/threonine protein kinase PknJ pepE (Rv2089c) — family_assigned: Xaa-Pro peptidase family protein Rv2091c (Rv2091c) — family_assigned: DUF4333 domain-containing protein helY (Rv2092c) — requalified: RNA helicase tatC (Rv2093c) — family_assigned: twin-arginine translocase subunit TatC tatA (Rv2094c) — family_assigned: Sec-independent protein translocase subunit TatA pafC (Rv2095c) — family_assigned: YafY family protein pafB (Rv2096c) — family_assigned: YafY family protein pafA (Rv2097c) — requalified: Pup--protein ligase helZ (Rv2101) — requalified: DEAD/DEAH box helicase vapC37 (Rv2103c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB37 (Rv2104c) — requalified: antitoxin prcA (Rv2109c) — family_assigned: proteasome subunit alpha prcB (Rv2110c) — family_assigned: proteasome subunit beta Rv2113 (Rv2113) — family_assigned: integral membrane protein Rv2114 (Rv2114) — dark: hypothetical protein mpa (Rv2115c) — requalified: proteasome ATPase lppK (Rv2116) — family_assigned: hypothetical protein Rv2117 (Rv2117) — family_assigned: DUF503 domain-containing protein trmI (Rv2118c) — requalified: tRNA (adenine(58)-N(1))-methyltransferase TrmI Rv2119 (Rv2119) — family_assigned: RecB family exonuclease Rv2120c (Rv2120c) — family_assigned: glycine zipper 2TM domain-containing protein hisG (Rv2121c) — requalified: ATP phosphoribosyltransferase metH (Rv2124c) — requalified: methionine synthase Rv2125 (Rv2125) — family_assigned: PAC2 family protein Rv2128 (Rv2128) — dark: hypothetical protein Rv2129c (Rv2129c) — family_assigned: SDR family oxidoreductase mshC (Rv2130c) — requalified: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyra cysQ (Rv2131c) — requalified: 3'(2')%2C5'-bisphosphate nucleotidase CysQ Rv2132 (Rv2132) — family_assigned: ribbon-helix-helix protein%2C CopG family Rv2133c (Rv2133c) — family_assigned: SCO1664 family protein Rv2135c (Rv2135c) — family_assigned: histidine phosphatase family protein Rv2136c (Rv2136c) — requalified: undecaprenyl-diphosphate phosphatase lppL (Rv2138) — family_assigned: hypothetical protein pyrD (Rv2139) — requalified: quinone-dependent dihydroorotate dehydrogenase TB18.6 (Rv2140c) — family_assigned: YbhB/YbcL family Raf kinase inhibitor-like protein parE2 (Rv2142c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2143 (Rv2143) — family_assigned: phosphoribosyltransferase family protein Rv2144c (Rv2144c) — dark: hypothetical protein wag31 (Rv2145c) — requalified: cell wall synthesis protein Wag31 Rv2146c (Rv2146c) — family_assigned: YggT family protein Rv2148c (Rv2148c) — family_assigned: YggS family pyridoxal phosphate-dependent enzyme ftsZ (Rv2150c) — requalified: cell division protein FtsZ ftsQ (Rv2151c) — requalified: cell division protein FtsQ murC (Rv2152c) — requalified: UDP-N-acetylmuramate--L-alanine ligase murG (Rv2153c) — requalified: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylgluc ftsW (Rv2154c) — family_assigned: putative lipid II flippase FtsW murD (Rv2155c) — requalified: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase murX (Rv2156c) — requalified: phospho-N-acetylmuramoyl-pentapeptide-transferase murF (Rv2157c) — requalified: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase murE (Rv2158c) — requalified: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopime Rv2159c (Rv2159c) — family_assigned: carboxymuconolactone decarboxylase family protein Rv2161c (Rv2161c) — family_assigned: TIGR03619 family F420-dependent LLM class oxidoreductase pbpB (Rv2163c) — requalified: D%2CD-transpeptidase PbpB Rv2164c (Rv2164c) — family_assigned: hypothetical protein rsmH (Rv2165c) — requalified: 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH mraZ (Rv2166c) — requalified: division/cell wall cluster transcriptional repressor MraZ Rv2169c (Rv2169c) — dark: DUF3040 domain-containing protein Rv2170 (Rv2170) — requalified: N-acetyltransferase lppM (Rv2171) — requalified: lipoprotein LppM Rv2172c (Rv2172c) — requalified: mycobacterial-type methylenetetrahydrofolate reductase idsA2 (Rv2173) — requalified: bifunctional (2E%2C6E)-farnesyl/geranyl diphosphate synthase mptA (Rv2174) — requalified: alpha-(1->6)-mannopyranosyltransferase A pknL (Rv2176) — requalified: protein kinase aroG (Rv2178c) — requalified: 3-deoxy-7-phosphoheptulonate synthase class II Rv2179c (Rv2179c) — requalified: polyadenylate-specific 3'-exoribonuclease AS Rv2180c (Rv2180c) — family_assigned: integral membrane protein Rv2181 (Rv2181) — requalified: alpha-(1-2)-phosphatidylinositol mannoside mannosyltransfera Rv2182c (Rv2182c) — family_assigned: lysophospholipid acyltransferase family protein Rv2183c (Rv2183c) — dark: hypothetical protein TB16.3 (Rv2185c) — family_assigned: SRPBCC family protein Rv2186c (Rv2186c) — requalified: polyketide cyclase / dehydrase and lipid transport fadD15 (Rv2187) — requalified: long-chain fatty acid--CoA ligase pimB (Rv2188c) — requalified: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monom Rv2189c (Rv2189c) — dark: hypothetical protein ripC (Rv2190c) — requalified: peptidoglycan hydrolase RipC trpD (Rv2192c) — requalified: anthranilate phosphoribosyltransferase ctaE (Rv2193) — family_assigned: heme-copper oxidase subunit III qcrC (Rv2194) — requalified: cytochrome c qcrB (Rv2196) — family_assigned: cytochrome bc complex cytochrome b subunit mmpS3 (Rv2198c) — family_assigned: MmpS family transport accessory protein Rv2199c (Rv2199c) — family_assigned: cytochrome c oxidase subunit 4 ctaC (Rv2200c) — family_assigned: cytochrome c oxidase subunit II asnB (Rv2201) — requalified: asparagine synthase (glutamine-hydrolyzing) adoK (Rv2202c) — family_assigned: carbohydrate kinase family protein Rv2203 (Rv2203) — dark: hypothetical protein Rv2204c (Rv2204c) — requalified: iron-sulfur cluster assembly accessory protein Rv2205c (Rv2205c) — requalified: glycerate kinase Rv2206 (Rv2206) — family_assigned: DUF3043 domain-containing protein cobT (Rv2207) — requalified: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosylt cobS (Rv2208) — requalified: adenosylcobinamide-GDP ribazoletransferase Rv2209 (Rv2209) — requalified: MFS transporter ilvE (Rv2210c) — requalified: branched-chain amino acid aminotransferase Rv2212 (Rv2212) — requalified: adenylyl cyclase pepB (Rv2213) — requalified: leucyl aminopeptidase ephD (Rv2214c) — family_assigned: SDR family oxidoreductase dlaT (Rv2215) — requalified: 2-oxoglutarate dehydrogenase%2C E2 component%2C dihydrolipoa Rv2216 (Rv2216) — family_assigned: TIGR01777 family oxidoreductase lipB (Rv2217) — requalified: lipoyl(octanoyl) transferase LipB lipA (Rv2218) — requalified: lipoyl synthase Rv2219 (Rv2219) — family_assigned: DUF4191 domain-containing protein glnA1 (Rv2220) — requalified: type I glutamate--ammonia ligase glnE (Rv2221c) — requalified: bifunctional [glutamine synthetase] adenylyltransferase/[glu glnA2 (Rv2222c) — family_assigned: glutamine synthetase family protein caeB (Rv2223c) — requalified: carboxylesterase CaeB caeA (Rv2224c) — requalified: carboxylesterase CaeA 2 385 kb 2 412 kb 2 438 kb 2 464 kb 2 491 kb 2 518 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.