MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 4 015 932–4 175 932 bp (160 000 bp)
+ strand − strand Rv3553 (Rv3553) — requalified: nitronate monooxygenase fdxB (Rv3554) — requalified: fatty acid desaturase Rv3555c (Rv3555c) — family_assigned: DUF559 domain-containing protein fadA6 (Rv3556c) — requalified: acetyl-CoA C-acetyltransferase kstR2 (Rv3557c) — family_assigned: TetR family transcriptional regulator KstR2 Rv3559c (Rv3559c) — family_assigned: SDR family oxidoreductase fadE30 (Rv3560c) — family_assigned: acyl-CoA dehydrogenase family protein fadD3 (Rv3561) — requalified: 3-((3aS%2C4S%2C7aS)-7a-methyl-1%2C5-dioxo-octahydro-1H-inden fadE31 (Rv3562) — family_assigned: acyl-CoA dehydrogenase family protein fadE32 (Rv3563) — family_assigned: acyl-CoA dehydrogenase family protein fadE33 (Rv3564) — family_assigned: acyl-CoA dehydrogenase family protein aspB (Rv3565) — requalified: pyridoxal phosphate-dependent aminotransferase hsaB (Rv3567c) — family_assigned: flavin-dependent monooxygenase reductase subunit HsaB hsaC (Rv3568c) — requalified: iron-dependent extradiol dioxygenase HsaC hsaD (Rv3569c) — requalified: alpha/beta fold hydrolase hsaA (Rv3570c) — family_assigned: flavin-dependent monooxygenase oxygenase subunit HsaA kshB (Rv3571) — family_assigned: 3-ketosteroid-9-alpha-hydroxylase reductase subunit Rv3572 (Rv3572) — family_assigned: hypothetical protein fadE34 (Rv3573c) — requalified: acyl-CoA dehydrogenase kstR (Rv3574) — family_assigned: cholesterol catabolism transcriptional regulator KstR Rv3575c (Rv3575c) — family_assigned: LacI family DNA-binding transcriptional regulator arsB2 (Rv3578) — requalified: arsenic transport integral membrane protein ArsB rlmB (Rv3579c) — requalified: 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB ispF (Rv3581c) — requalified: 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase ispD (Rv3582c) — requalified: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase carD (Rv3583c) — requalified: RNA polymerase-binding transcription factor CarD lpqE (Rv3584) — family_assigned: hypothetical protein radA (Rv3585) — requalified: DNA repair protein RadA disA (Rv3586) — requalified: DNA integrity scanning diadenylate cyclase DisA Rv3587c (Rv3587c) — family_assigned: hypothetical protein canB (Rv3588c) — requalified: beta-carbonic anhydrase CanB mutY (Rv3589) — requalified: A/G-specific adenine glycosylase Rv3591c (Rv3591c) — family_assigned: alpha/beta hydrolase mhuD (Rv3592) — requalified: mycobilin-forming heme oxygenase MhuD lpqF (Rv3593) — requalified: serine hydrolase Rv3594 (Rv3594) — requalified: N-acetylmuramoyl-L-alanine amidase lsr2 (Rv3597c) — requalified: histone-like nucleoid-structuring protein Lsr2 lysS (Rv3598c) — requalified: lysine--tRNA ligase Rv3600c (Rv3600c) — requalified: type III pantothenate kinase panD (Rv3601c) — requalified: aspartate 1-decarboxylase panC (Rv3602c) — requalified: pantoate--beta-alanine ligase Rv3603c (Rv3603c) — family_assigned: Rossmann-like and DUF2520 domain-containing protein Rv3604c (Rv3604c) — dark: DUF6779 domain-containing protein Rv3605c (Rv3605c) — family_assigned: DUF3180 domain-containing protein folK (Rv3606c) — requalified: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok folE (Rv3609c) — requalified: GTP cyclohydrolase I FolE ftsH (Rv3610c) — requalified: ATP-dependent zinc metalloprotease FtsH Rv3612c (Rv3612c) — dark: hypothetical protein Rv3613c (Rv3613c) — family_assigned: hypothetical protein espD (Rv3614c) — requalified: type VII secretion system ESX-1 target EspD espC (Rv3615c) — requalified: type VII secretion system ESX-1 filament-forming target EspC espA (Rv3616c) — requalified: type VII secretion system ESX-1 target EspA ephA (Rv3617) — requalified: epoxide hydrolase EphA Rv3618 (Rv3618) — requalified: LLM class flavin-dependent oxidoreductase esxI (Rv1037c) — requalified: type VII secretion system ESX-5 protein EsxL esxW (Rv3620c) — requalified: type VII secretion system protein EsxW lpqG (Rv3623) — family_assigned: SIMPL domain-containing protein hpt (Rv3624c) — requalified: hypoxanthine phosphoribosyltransferase mesJ (Rv3625c) — requalified: tRNA lysidine(34) synthetase TilS Rv3626c (Rv3626c) — requalified: zinc-dependent metalloprotease dacB (Rv3627c) — requalified: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endop ppa (Rv3628) — requalified: inorganic diphosphatase Rv3629c (Rv3629c) — family_assigned: DUF475 domain-containing protein Rv3630 (Rv3630) — family_assigned: hypothetical protein Rv3631 (Rv3631) — family_assigned: glycosyltransferase family 2 protein Rv3632 (Rv3632) — family_assigned: DUF2304 domain-containing protein Rv3633 (Rv3633) — family_assigned: phytanoyl-CoA dioxygenase family protein galE1 (Rv3634c) — requalified: UDP-glucose 4-epimerase Rv3635 (Rv3635) — family_assigned: hypothetical protein Rv3638 (Rv3638) — family_assigned: ATP-binding protein Rv3640c (Rv3640c) — family_assigned: IS256-like element IS1553 family transposase fic (Rv3641c) — family_assigned: Fic/DOC family protein Rv3642c (Rv3642c) — family_assigned: antitoxin VbhA family protein Rv3643 (Rv3643) — family_assigned: hypothetical protein Rv3644c (Rv3644c) — family_assigned: DNA polymerase III subunit delta' Rv3645 (Rv3645) — family_assigned: adenylate/guanylate cyclase domain-containing protein topA (Rv3646c) — requalified: type I DNA topoisomerase Rv3647c (Rv3647c) — family_assigned: hypothetical protein cspA (Rv3648c) — requalified: cold shock protein CspA Rv3649 (Rv3649) — requalified: DEAD/DEAH box helicase Rv3651 (Rv3651) — family_assigned: DUF5628 domain-containing protein Rv3655c (Rv3655c) — requalified: apoptosis inhibitor Rv3656c (Rv3656c) — dark: DUF4244 domain-containing protein Rv3658c (Rv3658c) — family_assigned: type II secretion system F family protein ssd (Rv3660c) — requalified: septum site-determining protein Ssd Rv3661 (Rv3661) — family_assigned: HAD-IB family hydrolase Rv3662c (Rv3662c) — requalified: oxidoreductase dppD (Rv3663c) — family_assigned: ABC transporter ATP-binding protein dppB (Rv3665c) — family_assigned: ABC transporter permease dppA (Rv3666c) — family_assigned: ABC transporter substrate-binding protein acs (Rv3667) — requalified: acetate--CoA ligase Rv3668c (Rv3668c) — requalified: protease Rv3669 (Rv3669) — family_assigned: phage holin family protein ephE (Rv3670) — family_assigned: alpha/beta hydrolase marP (Rv3671c) — requalified: acid resistance serine protease MarP Rv3672c (Rv3672c) — requalified: CoA pyrophosphatase nth (Rv3674c) — requalified: endonuclease III Rv3675 (Rv3675) — dark: hypothetical protein crp (Rv3676) — family_assigned: cAMP-activated global transcriptional regulator CRP Rv3677c (Rv3677c) — requalified: MBL fold metallo-hydrolase Rv3678c (Rv3678c) — family_assigned: RidA family protein Rv3679 (Rv3679) — family_assigned: ArsA family ATPase Rv3680 (Rv3680) — family_assigned: ArsA family ATPase whiB4 (Rv3681c) — family_assigned: transcriptional regulator WhiB4 Rv3683 (Rv3683) — requalified: metallophosphoesterase cyp137 (Rv3685c) — requalified: cytochrome P450 Rv3686c (Rv3686c) — dark: hypothetical protein rsfB (Rv3687c) — family_assigned: STAS domain-containing protein Rv3688c (Rv3688c) — family_assigned: GatB/YqeY domain-containing protein Rv3690 (Rv3690) — family_assigned: DUF4129 domain-containing protein moxR2 (Rv3692) — family_assigned: MoxR family ATPase Rv3693 (Rv3693) — family_assigned: DUF58 domain-containing protein Rv3694c (Rv3694c) — requalified: stage II sporulation protein M Rv3695 (Rv3695) — family_assigned: RDD family protein glpK (Rv3696c) — requalified: glycerol kinase GlpK vapC48 (Rv3697c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv3699 (Rv3699) — requalified: class I SAM-dependent methyltransferase egtE (Rv3700c) — requalified: ergothioneine biosynthesis PLP-dependent enzyme EgtE egtD (Rv3701c) — requalified: L-histidine N(alpha)-methyltransferase egtC (Rv3702c) — requalified: ergothioneine biosynthesis protein EgtC etgB (Rv3703c) — requalified: ergothioneine biosynthesis protein EgtB gshA (Rv3704c) — requalified: ergothioneine biosynthesis glutamate--cysteine ligase EgtA Rv3705c (Rv3705c) — family_assigned: sensor domain-containing protein Rv3706c (Rv3706c) — family_assigned: hypothetical protein asd (Rv3708c) — requalified: aspartate-semialdehyde dehydrogenase 4 028 kb 4 054 kb 4 081 kb 4 108 kb 4 134 kb 4 160 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.