MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

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+ strand − strand lldD2 (Rv1872c) — requalified: quinone-dependent L-lactate dehydrogenase Rv1873 (Rv1873) — family_assigned: DUF1810 domain-containing protein Rv1875 (Rv1875) — requalified: PPOX class F420-dependent oxidoreductase Rv1877 (Rv1877) — family_assigned: MDR family MFS transporter glnA3 (Rv1878) — family_assigned: glutamine synthetase family protein Rv1879 (Rv1879) — family_assigned: amidohydrolase family protein cyp140 (Rv1880c) — requalified: cytochrome P450 lppE (Rv1881c) — requalified: lipoprotein LpqH Rv1882c (Rv1882c) — family_assigned: SDR family oxidoreductase Rv1883c (Rv1883c) — family_assigned: SRPBCC family protein rpfC (Rv1884c) — requalified: resuscitation-promoting factor RpfC Rv1885c (Rv1885c) — requalified: chorismate mutase fbpB (Rv1886c) — requalified: diacylglycerol acyltransferase/mycolyltransferase Ag85B Rv1887 (Rv1887) — family_assigned: hypothetical protein Rv1891 (Rv1891) — dark: hypothetical protein Rv1892 (Rv1892) — family_assigned: hypothetical protein Rv1893 (Rv1893) — family_assigned: hypothetical protein Rv1894c (Rv1894c) — family_assigned: nitronate monooxygenase family protein Rv1896c (Rv1896c) — requalified: class I SAM-dependent methyltransferase dtd (Rv1897c) — requalified: D-aminoacyl-tRNA deacylase Rv1898 (Rv1898) — family_assigned: MTH1187 family thiamine-binding protein lipJ (Rv1900c) — family_assigned: adenylate/guanylate cyclase domain-containing protein cinA (Rv1901) — requalified: competence/damage-inducible protein A nanT (Rv1902c) — family_assigned: sialate:H+ symport family MFS transporter Rv1903 (Rv1903) — family_assigned: phage holin family protein Rv1904 (Rv1904) — requalified: anti-sigma factor antagonist aao (Rv1905c) — requalified: FAD-dependent oxidoreductase Rv1906c (Rv1906c) — family_assigned: hypothetical protein katG (Rv1908c) — requalified: catalase/peroxidase HPI furA (Rv1909c) — family_assigned: Fur family transcriptional regulator Rv1910c (Rv1910c) — family_assigned: YbhB/YbcL family Raf kinase inhibitor-like protein lppC (Rv1911c) — family_assigned: YbhB/YbcL family Raf kinase inhibitor-like protein fadB5 (Rv1912c) — family_assigned: medium chain dehydrogenase/reductase family protein Rv1913 (Rv1913) — requalified: MBL fold metallo-hydrolase Rv1914c (Rv1914c) — dark: hypothetical protein Rv1919c (Rv1919c) — family_assigned: SRPBCC family protein Rv1920 (Rv1920) — family_assigned: lysophospholipid acyltransferase family protein lppF (Rv1921c) — requalified: haloacid dehalogenase-like hydrolase Rv1922 (Rv1922) — requalified: serine hydrolase Rv1924c (Rv1924c) — family_assigned: hypothetical protein fadD31 (Rv1925) — requalified: fatty-acid--AMP ligase FAAL31/FadD31 mpt63 (Rv1926c) — requalified: immunoprotective protein Mpt63 Rv1927 (Rv1927) — family_assigned: YqjF family protein Rv1928c (Rv1928c) — family_assigned: SDR family oxidoreductase Rv1929c (Rv1929c) — family_assigned: TIGR03085 family metal-binding protein Rv1930c (Rv1930c) — requalified: glutamine amidotransferase tpx (Rv1932) — requalified: thiol peroxidase fadE18 (Rv1933c) — family_assigned: acyl-CoA dehydrogenase family protein fadE17 (Rv1934c) — requalified: acyl-CoA dehydrogenase echA13 (Rv1935c) — requalified: enoyl-CoA hydratase Rv1936 (Rv1936) — requalified: LLM class flavin-dependent oxidoreductase Rv1937 (Rv1937) — requalified: FAD-binding oxidoreductase ephB (Rv1938) — requalified: epoxide hydrolase EphB Rv1939 (Rv1939) — family_assigned: flavin reductase family protein Rv1941 (Rv1941) — family_assigned: SDR family oxidoreductase mazF5 (Rv1942c) — family_assigned: type II toxin-antitoxin system PemK/MazF family toxin mazE5 (Rv1943c) — requalified: type II toxin-antitoxin system antitoxin MazE5 Rv1944c (Rv1944c) — family_assigned: SEC-C domain-containing protein Rv1945 (Rv1945) — requalified: HNH endonuclease signature motif containing protein lppG (Rv1946c) — family_assigned: lipoprotein Rv1947 (Rv1947) — family_assigned: hypothetical protein Rv1948c (Rv1948c) — family_assigned: hypothetical protein Rv1950c (Rv1950c) — dark: hypothetical protein Rv1951c (Rv1951c) — dark: hypothetical protein vapB14 (Rv1952) — requalified: antitoxin Rv1954c (Rv1954c) — requalified: hypothetical protein higB (Rv1955) — requalified: type II toxin-antitoxin system toxin HigB higA (Rv1956) — requalified: type II toxin-antitoxin system antitoxin HigA Rv1957 (Rv1957) — requalified: SecB-like chaperone Rv1958c (Rv1958c) — dark: hypothetical protein parE1 (Rv1959c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin parD1 (Rv1960c) — family_assigned: type II toxin-antitoxin system ParD family antitoxin Rv1961 (Rv1961) — family_assigned: hypothetical protein vapC35 (Rv1962c) — family_assigned: type II toxin-antitoxin system VapC family toxin mce3R (Rv1963c) — family_assigned: TetR family transcriptional regulator Mce3R yrbE3A (Rv1964) — family_assigned: ABC transporter permease yrbE3B (Rv1965) — family_assigned: ABC transporter permease mce3B (Rv1967) — family_assigned: virulence factor Mce family protein mce3C (Rv1968) — family_assigned: virulence factor Mce family protein mce3D (Rv1969) — family_assigned: virulence factor Mce family protein lprM (Rv1970) — family_assigned: Mce family lipoprotein LprM mce3F (Rv1971) — family_assigned: MlaD family protein Rv1972 (Rv1972) — requalified: Mce associated membrane protein Rv1973 (Rv1973) — family_assigned: hypothetical protein Rv1974 (Rv1974) — family_assigned: DUF732 domain-containing protein Rv1975 (Rv1975) — family_assigned: CAP domain-containing protein Rv1976c (Rv1976c) — family_assigned: NYN domain-containing protein Rv1977 (Rv1977) — family_assigned: M48 family metallopeptidase Rv1978 (Rv1978) — requalified: class I SAM-dependent methyltransferase Rv1979c (Rv1979c) — family_assigned: APC family permease mpt64 (Rv1980c) — requalified: immunoprotective protein Mpt64 vapC36 (Rv1982c) — family_assigned: type II toxin-antitoxin system VapC family toxin cfp21 (Rv1984c) — requalified: cutinase Cfp21 Rv1985c (Rv1985c) — family_assigned: ArgP/LysG family DNA-binding transcriptional regulator lysE (Rv1986) — requalified: L-lysine exporter Rv1987 (Rv1987) — family_assigned: cellulose-binding protein Rv1989c (Rv1989c) — family_assigned: RES family NAD+ phosphorylase Rv1990c (Rv1990c) — family_assigned: antitoxin Xre/MbcA/ParS toxin-binding domain-containing prot mazF6 (Rv1991c) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF6 ctpG (Rv1992c) — requalified: cation transporter ATPase CptG Rv1993c (Rv1993c) — family_assigned: DUF1490 family protein cmtR (Rv1994c) — family_assigned: Cd(II)/Pb(II)-sensing metalloregulatory transcriptional regu Rv1995 (Rv1995) — family_assigned: hemerythrin domain-containing protein Rv1996 (Rv1996) — requalified: universal stress protein ctpF (Rv1997) — requalified: cation-transporting P-type ATPase Rv1998c (Rv1998c) — family_assigned: isocitrate lyase/phosphoenolpyruvate mutase family protein Rv1999c (Rv1999c) — family_assigned: APC family permease Rv2000 (Rv2000) — family_assigned: FAD/NAD(P)-binding protein Rv2001 (Rv2001) — requalified: acyl-[acyl-carrier-protein] thioesterase fabG3 (Rv2002) — family_assigned: SDR family oxidoreductase Rv2004c (Rv2004c) — family_assigned: AAA family ATPase Rv2005c (Rv2005c) — requalified: universal stress protein fdxA (Rv2007c) — family_assigned: ferredoxin family protein vapC15 (Rv2010) — family_assigned: PIN domain nuclease Rv2011c (Rv2011c) — family_assigned: MarR family winged helix-turn-helix transcriptional regulato Rv2015c (Rv2015c) — requalified: HNH endonuclease signature motif containing protein Rv2016 (Rv2016) — dark: hypothetical protein Rv2017 (Rv2017) — family_assigned: ImmA/IrrE family metallo-endopeptidase Rv2018 (Rv2018) — family_assigned: DUF433 domain-containing protein Rv2019 (Rv2019) — family_assigned: hypothetical protein Rv2021c (Rv2021c) — family_assigned: XRE family transcriptional regulator Rv2022c (Rv2022c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2023c (Rv2023c) — dark: hypothetical protein Rv2025c (Rv2025c) — family_assigned: cation diffusion facilitator family transporter 2 146 kb 2 173 kb 2 200 kb 2 226 kb 2 252 kb 2 279 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.