MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 404 619–1 564 619 bp (160 000 bp)
+ strand − strand Rv1251c (Rv1251c) — family_assigned: TM0106 family RecB-like putative nuclease lprE (Rv1252c) — family_assigned: LppP/LprE family lipoprotein deaD (Rv1253) — requalified: DEAD/DEAH box helicase Rv1254 (Rv1254) — requalified: acyltransferase Rv1255c (Rv1255c) — family_assigned: helix-turn-helix domain-containing protein cyp130 (Rv1256c) — requalified: cytochrome P450 Cyp130 Rv1257c (Rv1257c) — family_assigned: FAD-linked oxidase C-terminal domain-containing protein Rv1258c (Rv1258c) — requalified: MFS transporter Rv1260 (Rv1260) — family_assigned: FAD-binding protein Rv1261c (Rv1261c) — requalified: F420H(2)-dependent quinone reductase Rv1262c (Rv1262c) — family_assigned: HIT family protein amiB2 (Rv1263) — requalified: amidase Rv1264 (Rv1264) — requalified: adenylate cyclase pknH (Rv1266c) — requalified: serine/threonine protein kinase PknH embR (Rv1267c) — requalified: response regulator transcription factor EmbR Rv1268c (Rv1268c) — family_assigned: C39 family peptidase Rv1269c (Rv1269c) — family_assigned: DUF4189 domain-containing protein lprA (Rv1270c) — requalified: TLR2 agonist LprA Rv1271c (Rv1271c) — family_assigned: DUF732 domain-containing protein Rv1272c (Rv1272c) — family_assigned: fatty acid ABC transporter ATP-binding protein/permease Rv1273c (Rv1273c) — family_assigned: ABC transporter ATP-binding protein lprB (Rv1274) — family_assigned: DUF3558 domain-containing protein lprC (Rv1275) — family_assigned: DUF3558 domain-containing protein Rv1278 (Rv1278) — family_assigned: AAA family ATPase Rv1279 (Rv1279) — family_assigned: GMC family oxidoreductase N-terminal domain-containing prote oppA (Rv1280c) — family_assigned: oligopeptide ABC transporter substrate-binding protein OppA oppD (Rv1281c) — family_assigned: ABC transporter ATP-binding protein oppC (Rv1282c) — family_assigned: ABC transporter permease oppB (Rv1283c) — family_assigned: ABC transporter permease canA (Rv1284) — requalified: beta-carbonic anhydrase CanA cysD (Rv1285) — family_assigned: sulfate adenylyltransferase subunit CysD cysC (Rv1286) — requalified: adenylyl-sulfate kinase Rv1287 (Rv1287) — family_assigned: RrF2 family transcriptional regulator Rv1288 (Rv1288) — requalified: esterase Rv1289 (Rv1289) — family_assigned: hypothetical protein Rv1290c (Rv1290c) — family_assigned: DUF2254 domain-containing protein Rv1291c (Rv1291c) — family_assigned: DUF732 domain-containing protein argS (Rv1292) — requalified: arginine--tRNA ligase lysA (Rv1293) — requalified: diaminopimelate decarboxylase thrA (Rv1294) — requalified: homoserine dehydrogenase thrC (Rv1295) — requalified: threonine synthase thrB (Rv1296) — requalified: homoserine kinase rho (Rv1297) — requalified: transcription termination factor Rho rpmE (Rv1298) — requalified: 50S ribosomal protein L31 prfA (Rv1299) — requalified: peptide chain release factor 1 hemK (Rv1300) — requalified: peptide chain release factor N(5)-glutamine methyltransferas Rv1301 (Rv1301) — requalified: L-threonylcarbamoyladenylate synthase rfe (Rv1302) — requalified: UDP-N-acetylglucosamine--decaprenyl-phosphate N-acetylglucos Rv1303 (Rv1303) — family_assigned: ATP synthase subunit I atpB (Rv1304) — family_assigned: F0F1 ATP synthase subunit A atpE (Rv1305) — family_assigned: F0F1 ATP synthase subunit C atpF (Rv1306) — family_assigned: F0F1 ATP synthase subunit B atpH (Rv1307) — family_assigned: F0F1 ATP synthase subunit B/delta atpA (Rv1308) — family_assigned: F0F1 ATP synthase subunit alpha atpG (Rv1309) — family_assigned: F0F1 ATP synthase subunit gamma atpD (Rv1310) — family_assigned: F0F1 ATP synthase subunit beta atpC (Rv1311) — family_assigned: F0F1 ATP synthase subunit epsilon Rv1312 (Rv1312) — family_assigned: DUF2550 domain-containing protein Rv1314c (Rv1314c) — requalified: cob(I)yrinic acid a%2Cc-diamide adenosyltransferase murA (Rv1315) — requalified: UDP-N-acetylglucosamine 1-carboxyvinyltransferase ogt (Rv1316c) — requalified: methylated-DNA--protein-cysteine methyltransferase alkA (Rv1317c) — family_assigned: bifunctional regulatory protein/DNA repair enzyme AlkA Rv1318c (Rv1318c) — family_assigned: adenylate/guanylate cyclase domain-containing protein Rv1320c (Rv1320c) — family_assigned: adenylate/guanylate cyclase domain-containing protein Rv1322 (Rv1322) — family_assigned: hypothetical protein Rv1324 (Rv1324) — requalified: co-chaperone YbbN glgB (Rv1326c) — requalified: 1%2C4-alpha-glucan branching protein GlgB glgP (Rv1328) — family_assigned: glycosyltransferase family 1 protein dinG (Rv1329c) — requalified: ATP-dependent helicase DinG pncB1 (Rv1330c) — requalified: nicotinate phosphoribosyltransferase clpS (Rv1331) — requalified: ATP-dependent Clp protease adapter ClpS Rv1333 (Rv1333) — family_assigned: P1 family peptidase mec (Rv1334) — requalified: CysO-cysteine peptidase cysO (Rv1335) — requalified: sulfur carrier protein CysO cysM (Rv1336) — requalified: O-phosphoserine sulfhydrylase Rv1337 (Rv1337) — family_assigned: rhomboid family intramembrane serine protease murI (Rv1338) — requalified: glutamate racemase rphA (Rv1340) — requalified: ribonuclease PH rdgB (Rv1341) — family_assigned: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase lprD (Rv1343c) — family_assigned: hypothetical protein mbtM (Rv1345) — requalified: long-chain-fatty acid--ACP ligase MbtM mbtN (Rv1346) — requalified: acyl-ACP dehydrogenase MbtN mbtK (Rv1347c) — requalified: lysine N-acyltransferase MbtK irtA (Rv1348) — family_assigned: iron ABC transporter ATP-binding protein/permease IrtA irtB (Rv1349) — family_assigned: iron ABC transporter ATP-binding protein/permease IrtB fabG2 (Rv1350) — requalified: 3-oxoacyl-ACP reductase FabG Rv1352 (Rv1352) — family_assigned: hypothetical protein Rv1353c (Rv1353c) — family_assigned: TetR/AcrR family transcriptional regulator C-terminal domain Rv1354c (Rv1354c) — requalified: bifunctional diguanylate cyclase/phosphodiesterase moeY (Rv1355c) — family_assigned: Rv1355c family protein Rv1357c (Rv1357c) — requalified: cyclic diguanylate phosphodiesterase Rv1358 (Rv1358) — family_assigned: LuxR C-terminal-related transcriptional regulator Rv1360 (Rv1360) — requalified: LLM class F420-dependent oxidoreductase Rv1362c (Rv1362c) — family_assigned: hypothetical protein Rv1363c (Rv1363c) — dark: hypothetical protein rsfA (Rv1365c) — requalified: anti-sigma-F factor antagonist RsfA Rv1366 (Rv1366) — family_assigned: GTP pyrophosphokinase family protein lprF (Rv1368) — requalified: lipoprotein LprF Rv1371 (Rv1371) — family_assigned: cytochrome b5 domain-containing protein Rv1373 (Rv1373) — requalified: glycolipid sulfotransferase Rv1374c (Rv1374c) — dark: hypothetical protein Rv1375 (Rv1375) — family_assigned: YcaO-like family protein Rv1376 (Rv1376) — family_assigned: TfuA-like protein Rv1377c (Rv1377c) — requalified: class I SAM-dependent methyltransferase pyrR (Rv1379) — family_assigned: bifunctional pyr operon transcriptional regulator/uracil pho pyrB (Rv1380) — family_assigned: aspartate carbamoyltransferase catalytic subunit pyrC (Rv1381) — requalified: dihydroorotase 1 431 kb 1 458 kb 1 484 kb 1 510 kb 1 537 kb 1 564 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.