MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 834 863–1 994 863 bp (160 000 bp)
+ strand − strand cydB (Rv1622c) — family_assigned: cytochrome d ubiquinol oxidase subunit II Rv1624c (Rv1624c) — family_assigned: HdeD family acid-resistance protein cya (Rv1625c) — requalified: adenylate cyclase Rv1626 (Rv1626) — family_assigned: ANTAR domain-containing response regulator Rv1627c (Rv1627c) — requalified: lipid-transfer protein Rv1628c (Rv1628c) — family_assigned: Zn-ribbon domain-containing OB-fold protein polA (Rv1629) — requalified: DNA polymerase I rpsA (Rv1630) — requalified: 30S ribosomal protein S1 coaE (Rv1631) — requalified: dephospho-CoA kinase Rv1632c (Rv1632c) — family_assigned: DUF402 domain-containing protein Rv1634 (Rv1634) — requalified: MFS transporter Rv1635c (Rv1635c) — family_assigned: glycosyltransferase family 39 protein TB15.3 (Rv1636) — requalified: universal stress protein uvrA (Rv1638) — family_assigned: excinuclease ABC subunit UvrA Rv1639c (Rv1639c) — family_assigned: alpha/beta hydrolase family protein infC (Rv1641) — requalified: translation initiation factor IF-3 rplT (Rv1643) — requalified: 50S ribosomal protein L20 tsnR (Rv1644) — requalified: RNA methyltransferase Rv1645c (Rv1645c) — family_assigned: oxygenase MpaB family protein Rv1648 (Rv1648) — family_assigned: rhomboid-like protein pheT (Rv1650) — family_assigned: phenylalanine--tRNA ligase subunit beta argC (Rv1652) — requalified: N-acetyl-gamma-glutamyl-phosphate reductase argJ (Rv1653) — requalified: bifunctional glutamate N-acetyltransferase/amino-acid acetyl argB (Rv1654) — requalified: acetylglutamate kinase argD (Rv1655) — requalified: acetylornithine transaminase argF (Rv1656) — requalified: ornithine carbamoyltransferase argR (Rv1657) — requalified: arginine repressor argG (Rv1658) — requalified: argininosuccinate synthase argH (Rv1659) — requalified: argininosuccinate lyase pks10 (Rv1660) — requalified: type III polyketide synthase pks7 (Rv1661) — requalified: type I polyketide synthase pks7 pks9 (Rv1664) — requalified: type I polyketide synthase pks11 (Rv1665) — requalified: type III polyketide synthase cyp139 (Rv1666c) — requalified: cytochrome P450 Rv1669 (Rv1669) — dark: hypothetical protein Rv1670 (Rv1670) — family_assigned: DUF427 domain-containing protein Rv1671 (Rv1671) — dark: hypothetical protein Rv1672c (Rv1672c) — requalified: MFS transporter Rv1673c (Rv1673c) — family_assigned: transglutaminase family protein Rv1674c (Rv1674c) — family_assigned: metalloregulator ArsR/SmtB family transcription factor cmr (Rv1675c) — family_assigned: HTH-type transcriptional regulator Cmr Rv1676 (Rv1676) — family_assigned: peroxiredoxin-like family protein dsbF (Rv1677) — requalified: protein disulfide oxidoreductase Rv1678 (Rv1678) — family_assigned: hypothetical protein fadE16 (Rv1679) — family_assigned: acyl-CoA dehydrogenase family protein Rv1680 (Rv1680) — family_assigned: phosphate/phosphite/phosphonate ABC transporter substrate-bi moeX (Rv1681) — requalified: radical SAM protein Rv1683 (Rv1683) — requalified: acyl-CoA synthetase Rv1684 (Rv1684) — family_assigned: Trm112 family protein Rv1685c (Rv1685c) — family_assigned: TetR family transcriptional regulator Rv1687c (Rv1687c) — family_assigned: ABC transporter ATP-binding protein mpg (Rv1688) — requalified: DNA-3-methyladenine glycosylase tyrS (Rv1689) — requalified: tyrosine--tRNA ligase lprJ (Rv1690) — requalified: lipoprotein LprJ Rv1691 (Rv1691) — family_assigned: hypothetical protein Rv1692 (Rv1692) — family_assigned: HAD-IIA family hydrolase Rv1693 (Rv1693) — dark: hypothetical protein tlyA (Rv1694) — requalified: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA ppnK (Rv1695) — requalified: NAD kinase recN (Rv1696) — requalified: DNA repair protein RecN steA (Rv1697) — family_assigned: putative cytokinetic ring protein SteA mctB (Rv1698) — requalified: copper transporter MctB pyrG (Rv1699) — requalified: CTP synthase Rv1700 (Rv1700) — requalified: ADP-ribose diphosphatase xerD (Rv1701) — requalified: site-specific tyrosine recombinase XerD Rv1702c (Rv1702c) — requalified: HNH endonuclease signature motif containing protein Rv1703c (Rv1703c) — requalified: O-methyltransferase cycA (Rv1704c) — requalified: amino acid permease Rv1707 (Rv1707) — family_assigned: SulP family inorganic anion transporter scpA (Rv1709) — requalified: segregation/condensation protein A scpB (Rv1710) — family_assigned: SMC-Scp complex subunit ScpB Rv1711 (Rv1711) — requalified: pseudouridine synthase cmk (Rv1712) — requalified: (d)CMP kinase engA (Rv1713) — requalified: ribosome biogenesis GTPase Der Rv1714 (Rv1714) — family_assigned: SDR family oxidoreductase Rv1717 (Rv1717) — family_assigned: cupin domain-containing protein Rv1718 (Rv1718) — requalified: 3-keto-5-aminohexanoate cleavage protein Rv1719 (Rv1719) — family_assigned: IclR family transcriptional regulator vapC12 (Rv1720c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB12 (Rv1721c) — requalified: antitoxin Rv1722 (Rv1722) — requalified: biotin carboxylase Rv1723 (Rv1723) — requalified: serine hydrolase Rv1724c (Rv1724c) — dark: hypothetical protein Rv1725c (Rv1725c) — family_assigned: winged helix-turn-helix transcriptional regulator Rv1726 (Rv1726) — requalified: FAD-binding oxidoreductase Rv1727 (Rv1727) — family_assigned: TIGR03086 family metal-binding protein Rv1728c (Rv1728c) — requalified: glycoside hydrolase Rv1729c (Rv1729c) — requalified: class I SAM-dependent methyltransferase Rv1730c (Rv1730c) — family_assigned: serine hydrolase domain-containing protein gabD2 (Rv1731) — requalified: succinic semialdehyde dehydrogenase Rv1732c (Rv1732c) — family_assigned: thioredoxin family protein Rv1733c (Rv1733c) — family_assigned: hypothetical protein narX (Rv1736c) — family_assigned: respiratory nitrate reductase subunit gamma narK2 (Rv1737c) — requalified: nitrate transporter NarK Rv1738 (Rv1738) — family_assigned: DUF1876 domain-containing protein Rv1739c (Rv1739c) — family_assigned: SulP family inorganic anion transporter vapB34 (Rv1740) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC34 (Rv1741) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv1742 (Rv1742) — family_assigned: hypothetical protein pknE (Rv1743) — requalified: serine/threonine protein kinase PknE Rv1744c (Rv1744c) — dark: hypothetical protein idi (Rv1745c) — requalified: isopentenyl-diphosphate Delta-isomerase pknF (Rv1746) — requalified: serine/threonine protein kinase PknF Rv1747 (Rv1747) — family_assigned: ATP-binding cassette domain-containing protein Rv1749c (Rv1749c) — family_assigned: DUF6790 family protein fadD1 (Rv1750c) — requalified: fatty-acid--CoA ligase FadD1 1 855 kb 1 882 kb 1 908 kb 1 934 kb 1 961 kb 1 988 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.