MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

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+ strand − strand dacB (Rv3627c) — requalified: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endop ppa (Rv3628) — requalified: inorganic diphosphatase Rv3629c (Rv3629c) — family_assigned: DUF475 domain-containing protein Rv3630 (Rv3630) — family_assigned: hypothetical protein Rv3631 (Rv3631) — family_assigned: glycosyltransferase family 2 protein Rv3632 (Rv3632) — family_assigned: DUF2304 domain-containing protein Rv3633 (Rv3633) — family_assigned: phytanoyl-CoA dioxygenase family protein galE1 (Rv3634c) — requalified: UDP-glucose 4-epimerase Rv3635 (Rv3635) — family_assigned: hypothetical protein Rv3638 (Rv3638) — family_assigned: ATP-binding protein Rv3640c (Rv3640c) — family_assigned: IS256-like element IS1553 family transposase fic (Rv3641c) — family_assigned: Fic/DOC family protein Rv3642c (Rv3642c) — family_assigned: antitoxin VbhA family protein Rv3643 (Rv3643) — family_assigned: hypothetical protein Rv3644c (Rv3644c) — family_assigned: DNA polymerase III subunit delta' Rv3645 (Rv3645) — family_assigned: adenylate/guanylate cyclase domain-containing protein topA (Rv3646c) — requalified: type I DNA topoisomerase Rv3647c (Rv3647c) — family_assigned: hypothetical protein cspA (Rv3648c) — requalified: cold shock protein CspA Rv3649 (Rv3649) — requalified: DEAD/DEAH box helicase Rv3651 (Rv3651) — family_assigned: DUF5628 domain-containing protein Rv3655c (Rv3655c) — requalified: apoptosis inhibitor Rv3656c (Rv3656c) — dark: DUF4244 domain-containing protein Rv3658c (Rv3658c) — family_assigned: type II secretion system F family protein ssd (Rv3660c) — requalified: septum site-determining protein Ssd Rv3661 (Rv3661) — family_assigned: HAD-IB family hydrolase Rv3662c (Rv3662c) — requalified: oxidoreductase dppD (Rv3663c) — family_assigned: ABC transporter ATP-binding protein dppB (Rv3665c) — family_assigned: ABC transporter permease dppA (Rv3666c) — family_assigned: ABC transporter substrate-binding protein acs (Rv3667) — requalified: acetate--CoA ligase Rv3668c (Rv3668c) — requalified: protease Rv3669 (Rv3669) — family_assigned: phage holin family protein ephE (Rv3670) — family_assigned: alpha/beta hydrolase marP (Rv3671c) — requalified: acid resistance serine protease MarP Rv3672c (Rv3672c) — requalified: CoA pyrophosphatase nth (Rv3674c) — requalified: endonuclease III Rv3675 (Rv3675) — dark: hypothetical protein crp (Rv3676) — family_assigned: cAMP-activated global transcriptional regulator CRP Rv3677c (Rv3677c) — requalified: MBL fold metallo-hydrolase Rv3678c (Rv3678c) — family_assigned: RidA family protein Rv3679 (Rv3679) — family_assigned: ArsA family ATPase Rv3680 (Rv3680) — family_assigned: ArsA family ATPase whiB4 (Rv3681c) — family_assigned: transcriptional regulator WhiB4 Rv3683 (Rv3683) — requalified: metallophosphoesterase cyp137 (Rv3685c) — requalified: cytochrome P450 Rv3686c (Rv3686c) — dark: hypothetical protein rsfB (Rv3687c) — family_assigned: STAS domain-containing protein Rv3688c (Rv3688c) — family_assigned: GatB/YqeY domain-containing protein Rv3690 (Rv3690) — family_assigned: DUF4129 domain-containing protein moxR2 (Rv3692) — family_assigned: MoxR family ATPase Rv3693 (Rv3693) — family_assigned: DUF58 domain-containing protein Rv3694c (Rv3694c) — requalified: stage II sporulation protein M Rv3695 (Rv3695) — family_assigned: RDD family protein glpK (Rv3696c) — requalified: glycerol kinase GlpK vapC48 (Rv3697c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv3699 (Rv3699) — requalified: class I SAM-dependent methyltransferase egtE (Rv3700c) — requalified: ergothioneine biosynthesis PLP-dependent enzyme EgtE egtD (Rv3701c) — requalified: L-histidine N(alpha)-methyltransferase egtC (Rv3702c) — requalified: ergothioneine biosynthesis protein EgtC etgB (Rv3703c) — requalified: ergothioneine biosynthesis protein EgtB gshA (Rv3704c) — requalified: ergothioneine biosynthesis glutamate--cysteine ligase EgtA Rv3705c (Rv3705c) — family_assigned: sensor domain-containing protein Rv3706c (Rv3706c) — family_assigned: hypothetical protein asd (Rv3708c) — requalified: aspartate-semialdehyde dehydrogenase ask (Rv3709c) — requalified: aspartate kinase leuA (Rv3710) — requalified: 2-isopropylmalate synthase dnaQ (Rv3711c) — family_assigned: DEDDh family exonuclease Rv3712 (Rv3712) — family_assigned: Mur ligase family protein cobQ2 (Rv3713) — requalified: type 1 glutamine amidotransferase Rv3714c (Rv3714c) — family_assigned: hypothetical protein recR (Rv3715c) — requalified: recombination mediator RecR Rv3716c (Rv3716c) — family_assigned: YbaB/EbfC family nucleoid-associated protein Rv3718c (Rv3718c) — family_assigned: SRPBCC family protein dnaZX (Rv3721c) — family_assigned: DNA polymerase III subunits gamma/tau Rv3722c (Rv3722c) — requalified: aminotransferase lucA (Rv3723) — requalified: lipid uptake coordinator LucA Rv3726 (Rv3726) — requalified: zinc-binding dehydrogenase Rv3727 (Rv3727) — requalified: FAD-dependent oxidoreductase Rv3728 (Rv3728) — requalified: MFS transporter ligD (Rv3730c) — requalified: non-homologous end-joining DNA ligase ligC (Rv3731) — requalified: ATP-dependent DNA ligase Rv3732 (Rv3732) — dark: DUF2330 domain-containing protein Rv3733c (Rv3733c) — family_assigned: NUDIX domain-containing protein tgs2 (Rv3734c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase Rv3735 (Rv3735) — requalified: adenosine-specific kinase Rv3736 (Rv3736) — family_assigned: AraC family transcriptional regulator Rv3737 (Rv3737) — family_assigned: threonine/serine exporter family protein Rv3740c (Rv3740c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase ctpJ (Rv3743c) — requalified: heavy metal translocating P-type ATPase nmtR (Rv3744) — requalified: Ni(II)/Co(II)-sensing metalloregulatory transcriptional repr Rv3747 (Rv3747) — dark: hypothetical protein Rv3748 (Rv3748) — family_assigned: hypothetical protein Rv3752c (Rv3752c) — requalified: nucleoside deaminase Rv3755c (Rv3755c) — family_assigned: putative glycolipid-binding domain-containing protein proZ (Rv3756c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter proW (Rv3757c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter proV (Rv3758c) — family_assigned: glycine betaine/L-proline ABC transporter ATP-binding protei proX (Rv3759c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter fadE36 (Rv3761c) — family_assigned: phosphotransferase family protein Rv3762c (Rv3762c) — requalified: alkyl/aryl-sulfatase lpqH (Rv3763) — requalified: lipoprotein LpqH tcrX (Rv3765c) — requalified: two-component system response regulator TcrX Rv3767c (Rv3767c) — requalified: class I SAM-dependent methyltransferase Rv3768 (Rv3768) — family_assigned: nuclear transport factor 2 family protein Rv3769 (Rv3769) — family_assigned: hypothetical protein Rv3770c (Rv3770c) — family_assigned: hypothetical protein Rv2812 (Rv2812) — family_assigned: helix-turn-helix domain-containing protein Rv3771c (Rv3771c) — family_assigned: hypothetical protein hisC2 (Rv3772) — requalified: histidinol-phosphate transaminase Rv3773c (Rv3773c) — family_assigned: TIGR03086 family metal-binding protein echA21 (Rv3774) — family_assigned: crotonase/enoyl-CoA hydratase family protein lipE (Rv3775) — requalified: lipase LipE Rv3778c (Rv3778c) — family_assigned: cysteine desulfurase-like protein Rv3779 (Rv3779) — family_assigned: DUF6541 family protein 4 108 kb 4 134 kb 4 160 kb 4 187 kb 4 214 kb 4 240 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.