MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 4 183 802–4 383 802 bp (200 000 bp)
+ strand − strand Rv3714c (Rv3714c) — family_assigned: hypothetical protein recR (Rv3715c) — requalified: recombination mediator RecR Rv3716c (Rv3716c) — family_assigned: YbaB/EbfC family nucleoid-associated protein Rv3718c (Rv3718c) — family_assigned: SRPBCC family protein dnaZX (Rv3721c) — family_assigned: DNA polymerase III subunits gamma/tau Rv3722c (Rv3722c) — requalified: aminotransferase lucA (Rv3723) — requalified: lipid uptake coordinator LucA Rv3726 (Rv3726) — requalified: zinc-binding dehydrogenase Rv3727 (Rv3727) — requalified: FAD-dependent oxidoreductase Rv3728 (Rv3728) — requalified: MFS transporter ligD (Rv3730c) — requalified: non-homologous end-joining DNA ligase ligC (Rv3731) — requalified: ATP-dependent DNA ligase Rv3732 (Rv3732) — dark: DUF2330 domain-containing protein Rv3733c (Rv3733c) — family_assigned: NUDIX domain-containing protein tgs2 (Rv3734c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase Rv3735 (Rv3735) — requalified: adenosine-specific kinase Rv3736 (Rv3736) — family_assigned: AraC family transcriptional regulator Rv3737 (Rv3737) — family_assigned: threonine/serine exporter family protein Rv3740c (Rv3740c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase ctpJ (Rv3743c) — requalified: heavy metal translocating P-type ATPase nmtR (Rv3744) — requalified: Ni(II)/Co(II)-sensing metalloregulatory transcriptional repr Rv3747 (Rv3747) — dark: hypothetical protein Rv3748 (Rv3748) — family_assigned: hypothetical protein Rv3752c (Rv3752c) — requalified: nucleoside deaminase Rv3755c (Rv3755c) — family_assigned: putative glycolipid-binding domain-containing protein proZ (Rv3756c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter proW (Rv3757c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter proV (Rv3758c) — family_assigned: glycine betaine/L-proline ABC transporter ATP-binding protei proX (Rv3759c) — family_assigned: glycine betaine/carnitine/choline/L-proline ABC transporter fadE36 (Rv3761c) — family_assigned: phosphotransferase family protein Rv3762c (Rv3762c) — requalified: alkyl/aryl-sulfatase lpqH (Rv3763) — requalified: lipoprotein LpqH tcrX (Rv3765c) — requalified: two-component system response regulator TcrX Rv3767c (Rv3767c) — requalified: class I SAM-dependent methyltransferase Rv3768 (Rv3768) — family_assigned: nuclear transport factor 2 family protein Rv3769 (Rv3769) — family_assigned: hypothetical protein Rv3770c (Rv3770c) — family_assigned: hypothetical protein Rv2812 (Rv2812) — family_assigned: helix-turn-helix domain-containing protein Rv3771c (Rv3771c) — family_assigned: hypothetical protein hisC2 (Rv3772) — requalified: histidinol-phosphate transaminase Rv3773c (Rv3773c) — family_assigned: TIGR03086 family metal-binding protein echA21 (Rv3774) — family_assigned: crotonase/enoyl-CoA hydratase family protein lipE (Rv3775) — requalified: lipase LipE Rv3778c (Rv3778c) — family_assigned: cysteine desulfurase-like protein Rv3779 (Rv3779) — family_assigned: DUF6541 family protein bpa (Rv3780) — requalified: proteasome activator protein Bpa rfbE (Rv3781) — family_assigned: ABC transporter ATP-binding protein rfbD (Rv3783) — family_assigned: ABC transporter permease Rv3785 (Rv3785) — family_assigned: hypothetical protein Rv3786c (Rv3786c) — family_assigned: peptidoglycan DD-metalloendopeptidase family protein Rv3787c (Rv3787c) — requalified: class I SAM-dependent methyltransferase Rv3788 (Rv3788) — family_assigned: GreA/GreB family elongation factor Rv3789 (Rv3789) — requalified: arabinogalactan biosynthesis protein dprE1 (Rv3790) — requalified: decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase DprE1 aftA (Rv3792) — requalified: galactan 5-O-arabinofuranosyltransferase embC (Rv3793) — requalified: arabinosyltransferase EmbC embA (Rv3794) — requalified: arabinosyltransferase EmbA embB (Rv3795) — requalified: arabinosyltransferase EmbB fadE35 (Rv3797) — requalified: DNA alkylation response protein Rv1313c (Rv1313c) — family_assigned: ISL3-like element IS1557 family transposase accD4 (Rv3799c) — family_assigned: acyl-CoA carboxylase subunit beta pks13 (Rv3800c) — requalified: polyketide synthase Pks13 pks13 Rv3802c (Rv3802c) — requalified: phospholipase fbpA (Rv3804c) — requalified: diacylglycerol acyltransferase/mycolyltransferase Ag85A ubiA (Rv3806c) — requalified: decaprenyl-phosphate phosphoribosyltransferase glfT2 (Rv3808c) — requalified: galactofuranosyl transferase GlfT2 glf (Rv3809c) — requalified: UDP-galactopyranose mutase pirG (Rv3810) — requalified: exported repetitive protein Rv3813c (Rv3813c) — family_assigned: Cof-type HAD-IIB family hydrolase Rv3814c (Rv3814c) — requalified: 1-acyl-sn-glycerol-3-phosphate acyltransferase Rv3815c (Rv3815c) — family_assigned: lysophospholipid acyltransferase family protein Rv3816c (Rv3816c) — requalified: 1-acyl-sn-glycerol-3-phosphate acyltransferase Rv3817 (Rv3817) — requalified: aminoglycoside 3'-phosphotransferase Rv3818 (Rv3818) — requalified: MBL fold metallo-hydrolase Rv3819 (Rv3819) — dark: hypothetical protein sap (Rv3821) — requalified: sulfolipid-1 biosynthesis transporter Sap chp1 (Rv3822) — requalified: sulfolipid-1 biosynthesis membrane-anchored acyltransferase mmpL8 (Rv3823c) — requalified: sulfolipid-1 RND transporter MmpL8 papA1 (Rv3824c) — requalified: acyltransferase PapA1 pks2 (Rv3825c) — requalified: phthioceranic/hydroxyphthioceranic acid synthase pks2 fadD23 (Rv3826) — requalified: long-chain-fatty-acid--CoA ligase FadD23 tnpB (Rv2791c) — family_assigned: IS607 family element RNA-guided endonuclease TnpB Rv2792c (Rv2792c) — family_assigned: IS607-like element IS1537 family transposase Rv3829c (Rv3829c) — requalified: NAD(P)/FAD-dependent oxidoreductase Rv3830c (Rv3830c) — family_assigned: TetR/AcrR family transcriptional regulator Rv3831 (Rv3831) — family_assigned: DUF2834 domain-containing protein Rv3832c (Rv3832c) — family_assigned: methyltransferase domain-containing protein Rv3833 (Rv3833) — family_assigned: helix-turn-helix transcriptional regulator serS (Rv3834c) — requalified: serine--tRNA ligase Rv3835 (Rv3835) — family_assigned: septum formation family protein Rv3836 (Rv3836) — family_assigned: metallopeptidase family protein Rv3837c (Rv3837c) — family_assigned: histidine phosphatase family protein pheA (Rv3838c) — requalified: prephenate dehydratase Rv3839 (Rv3839) — requalified: DUF2470 domain-containing protein bfrB (Rv3841) — requalified: ferritin BfrB glpQ1 (Rv3842c) — requalified: glycerophosphodiester phosphodiesterase Rv3843c (Rv3843c) — family_assigned: DUF4328 domain-containing protein Rv3845 (Rv3845) — family_assigned: IS110 family transposase sodA (Rv3846) — requalified: superoxide dismutase Rv3847 (Rv3847) — requalified: peptidase Rv3848 (Rv3848) — family_assigned: TMEM165/GDT1 family protein espR (Rv3849) — family_assigned: type VII secretion system ESX-1 transcriptional regulator Es Rv3850 (Rv3850) — family_assigned: DUF6474 family protein Rv3851 (Rv3851) — dark: hypothetical protein hns (Rv3852) — family_assigned: histone-like protein Hns rraA (Rv3853) — requalified: ribonuclease E activity regulator RraA ethA (Rv3854c) — requalified: FAD-containing monooxygenase EthA ethR (Rv3855) — family_assigned: HTH-type transcriptional regulator EthR Rv3856c (Rv3856c) — family_assigned: PHP domain-containing protein gltD (Rv3858c) — family_assigned: glutamate synthase subunit beta gltB (Rv3859c) — family_assigned: glutamate synthase large subunit Rv3860 (Rv3860) — requalified: ATPase Rv3861 (Rv3861) — dark: hypothetical protein espE (Rv3864) — requalified: type VII secretion system ESX-1 associated protein EspE espF (Rv3865) — requalified: type VII secretion system ESX-1 associated protein EspF espG1 (Rv3866) — requalified: type VII secretion system ESX-1 adaptor EspG1 espH (Rv3867) — requalified: type VII secretion system ESX-1 associated protein EspH eccA1 (Rv3868) — family_assigned: type VII secretion system ESX-1 AAA family ATPase EccA1 eccB1 (Rv3869) — family_assigned: type VII secretion system ESX-1 subunit EccB1 eccCa1 (Rv3870) — family_assigned: type VII secretion system ESX-1 FtsK/SpoIIIE family ATPase E eccCb1 (Rv3871) — family_assigned: type VII secretion system ESX-1 FtsK/SpoIIIE family ATPase E esxB (Rv3874) — family_assigned: type VII secretion system ESX-1 WXG100 family target CFP-10 espI (Rv3876) — family_assigned: MinD/ParA family protein eccD1 (Rv3877) — family_assigned: type VII secretion system ESX-1 subunit EccD1 espJ (Rv3878) — requalified: type VII secretion system ESX-1 associated protein EspJ 4 188 kb 4 221 kb 4 254 kb 4 288 kb 4 322 kb 4 355 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.