MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 649 305–3 809 305 bp (160 000 bp)
+ strand − strand mtrA (Rv3246c) — requalified: two-component system response regulator MtrA tmk (Rv3247c) — requalified: dTMP kinase sahH (Rv3248c) — requalified: adenosylhomocysteinase Rv3249c (Rv3249c) — family_assigned: TetR family transcriptional regulator rubB (Rv3250c) — requalified: rubredoxin RubB rubA (Rv3251c) — requalified: rubredoxin alkB (Rv3252c) — requalified: alkane 1-monooxygenase Rv3253c (Rv3253c) — requalified: amino acid permease Rv3254 (Rv3254) — requalified: oxidoreductase manA (Rv3255c) — requalified: mannose-6-phosphate isomerase%2C class I Rv3256c (Rv3256c) — requalified: TobH protein pmmA (Rv3257c) — requalified: phosphomannomutase/phosphoglucomutase Rv3259 (Rv3259) — family_assigned: metallopeptidase family protein fbiA (Rv3261) — requalified: 2-phospho-L-lactate transferase fbiB (Rv3262) — requalified: coenzyme F420-0:L-glutamate ligase Rv3263 (Rv3263) — requalified: class I SAM-dependent methyltransferase rmlD (Rv3266c) — requalified: dTDP-4-dehydrorhamnose reductase lcp1 (Rv3267) — requalified: phosphotransferase Lcp1 Rv3269 (Rv3269) — family_assigned: DUF1490 family protein ctpC (Rv3270) — requalified: manganese-exporting P-type ATPase CtpC Rv3271c (Rv3271c) — requalified: cation transporter Rv3272 (Rv3272) — requalified: CoA transferase fadE25 (Rv3274c) — requalified: acyl-CoA dehydrogenase purE (Rv3275c) — requalified: 5-(carboxyamino)imidazole ribonucleotide mutase purK (Rv3276c) — requalified: 5-(carboxyamino)imidazole ribonucleotide synthase Rv3278c (Rv3278c) — family_assigned: PH domain-containing protein birA (Rv3279c) — requalified: biotin--[acetyl-CoA-carboxylase] ligase accD5 (Rv3280) — family_assigned: acyl-CoA carboxylase subunit beta accE5 (Rv3281) — family_assigned: acyl-CoA carboxylase subunit epsilon Rv3282 (Rv3282) — requalified: nucleoside triphosphate pyrophosphatase sseA (Rv3283) — requalified: sulfurtransferase Rv3284 (Rv3284) — family_assigned: SufE family protein accA3 (Rv3285) — family_assigned: acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alph sigF (Rv3286c) — requalified: RNA polymerase sigma factor SigF rsbW (Rv3287c) — requalified: anti-sigma B factor RsbW Rv3289c (Rv3289c) — dark: hypothetical protein lat (Rv3290c) — requalified: L-lysine 6-transaminase lrpA (Rv3291c) — family_assigned: transcriptional regulator LrpA Rv3292 (Rv3292) — family_assigned: VOC family protein Rv3295 (Rv3295) — family_assigned: TetR/AcrR family transcriptional regulator lhr (Rv3296) — requalified: ATP-dependent helicase lhr nei (Rv3297) — requalified: endonuclease VIII Nei2 lpqC (Rv3298c) — family_assigned: PHB depolymerase family esterase atsB (Rv3299c) — requalified: arylsulfatase AtsB Rv3300c (Rv3300c) — family_assigned: RluA family pseudouridine synthase phoY1 (Rv3301c) — requalified: phosphate signaling complex protein PhoU glpD2 (Rv3302c) — requalified: glycerol-3-phosphate dehydrogenase/oxidase lpdA (Rv3303c) — requalified: NAD(P)H-quinone dehydrogenase Rv3304 (Rv3304) — requalified: gamma-glutamylcyclotransferase deoD (Rv3307) — requalified: purine-nucleoside phosphorylase pmmB (Rv3308) — requalified: phospho-sugar mutase upp (Rv3309c) — requalified: uracil phosphoribosyltransferase sapM (Rv3310) — requalified: phosphatidylinositol-3-phosphatase Rv3311 (Rv3311) — family_assigned: primosomal protein Rv3312c (Rv3312c) — family_assigned: alpha/beta hydrolase add (Rv3313c) — requalified: adenosine deaminase deoA (Rv3314c) — requalified: thymidine phosphorylase cdd (Rv3315c) — requalified: cytidine deaminase sdhC (Rv3316) — family_assigned: succinate dehydrogenase%2C cytochrome b556 subunit sdhD (Rv3317) — family_assigned: succinate dehydrogenase hydrophobic membrane anchor subunit sdhA (Rv3318) — family_assigned: succinate dehydrogenase flavoprotein subunit sdhB (Rv3319) — family_assigned: succinate dehydrogenase iron-sulfur subunit vapC44 (Rv3320c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB44 (Rv3321c) — family_assigned: CopG family transcriptional regulator moaC3 (Rv3324c) — requalified: cyclic pyranopterin monophosphate synthase MoaC Rv3327 (Rv3327) — family_assigned: IS110 family transposase sigJ (Rv3328c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigJ dacB1 (Rv3330) — requalified: D-alanyl-D-alanine carboxypeptidase DacB1 nagA (Rv3332) — requalified: N-acetylglucosamine-6-phosphate deacetylase prp1 (Rv3333c) — requalified: PDZ-interacting protease regulator Ppr1 Rv3334 (Rv3334) — family_assigned: hypoxia response transcriptional regulator yhjD (Rv3335c) — requalified: inner membrane protein YhjD trpS (Rv3336c) — requalified: tryptophan--tRNA ligase icd1 (Rv3339c) — requalified: NADP-dependent isocitrate dehydrogenase metC (Rv3340) — requalified: bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase metA (Rv3341) — requalified: homoserine O-acetyltransferase Rv3342 (Rv3342) — requalified: class I SAM-dependent methyltransferase Rv3346c (Rv3346c) — dark: DUF3017 domain-containing protein Rv3353c (Rv3353c) — requalified: oxidoreductase Rv3354 (Rv3354) — requalified: DUF732 domain-containing protein Rv3355c (Rv3355c) — dark: DUF3017 domain-containing protein relJ (Rv3357) — requalified: type II toxin-antitoxin system antitoxin RelJ relK (Rv3358) — family_assigned: Txe/YoeB family addiction module toxin Rv3359 (Rv3359) — requalified: NADH:flavin oxidoreductase Rv3360 (Rv3360) — family_assigned: FHA domain-containing protein mfpA (Rv3361c) — requalified: pentapeptide repeat protein MfpA Rv3362c (Rv3362c) — family_assigned: ATP/GTP-binding protein Rv3363c (Rv3363c) — family_assigned: DUF742 domain-containing protein Rv3364c (Rv3364c) — requalified: serine protease inhibitor Rv3365c (Rv3365c) — requalified: sensor histidine kinase spoU (Rv3366) — requalified: tRNA (cytidine(34)-2'-O)-methyltransferase Rv3368c (Rv3368c) — family_assigned: nitroreductase family protein 3 657 kb 3 684 kb 3 710 kb 3 736 kb 3 763 kb 3 790 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.