MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 213 213–373 213 bp (160 000 bp)
+ strand − strand Rv0181c (Rv0181c) — family_assigned: pirin family protein sigG (Rv0182c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigG Rv0183 (Rv0183) — requalified: monoacylglycerol lipase Rv0184 (Rv0184) — dark: DUF2786 domain-containing protein Rv0185 (Rv0185) — family_assigned: TIGR04338 family metallohydrolase Rv0187 (Rv0187) — requalified: O-methyltransferase Rv0188 (Rv0188) — requalified: SPW repeat protein ilvD (Rv0189c) — requalified: dihydroxy-acid dehydratase Rv0190 (Rv0190) — family_assigned: metal-sensitive transcriptional regulator Rv0191 (Rv0191) — family_assigned: Rv0191 family MFS efflux transporter Rv0193c (Rv0193c) — family_assigned: hypothetical protein Rv0194 (Rv0194) — family_assigned: ABC transporter ATP-binding protein Rv0195 (Rv0195) — requalified: response regulator transcription factor Rv0196 (Rv0196) — family_assigned: TetR/AcrR family transcriptional regulator zmp1 (Rv0198c) — requalified: zinc metalloprotease Zmp1 omamA (Rv0199) — requalified: hypothetical protein omamB (Rv0200) — requalified: hypothetical protein Rv0201c (Rv0201c) — family_assigned: XRE family transcriptional regulator mmpL11 (Rv0202c) — requalified: RND transporter MmpL11 Rv0203 (Rv0203) — requalified: hemophore Rv0204c (Rv0204c) — family_assigned: TIGR00374 family protein Rv0205 (Rv0205) — family_assigned: AI-2E family transporter mmpL3 (Rv0206c) — requalified: trehalose monomycolate RND transporter MmpL3 Rv0207c (Rv0207c) — family_assigned: NYN domain-containing protein trmB (Rv0208c) — requalified: tRNA (guanosine(46)-N7)-methyltransferase TrmB Rv0209 (Rv0209) — family_assigned: hypothetical protein Rv0210 (Rv0210) — family_assigned: hypothetical protein pckA (Rv0211) — requalified: phosphoenolpyruvate carboxykinase (GTP) nadR (Rv0212c) — requalified: nicotinamide-nucleotide adenylyltransferase Rv0216 (Rv0216) — family_assigned: MaoC family dehydratase lipW (Rv0217c) — family_assigned: alpha/beta hydrolase Rv0218 (Rv0218) — requalified: molybdopterin-dependent oxidoreductase Rv0219 (Rv0219) — dark: hypothetical protein lipC (Rv0220) — requalified: esterase LipC Rv0221 (Rv0221) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase echA1 (Rv0222) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0223c (Rv0223c) — requalified: aldehyde dehydrogenase Rv0224c (Rv0224c) — requalified: class I SAM-dependent methyltransferase Rv0225 (Rv0225) — family_assigned: glycosyltransferase family 4 protein mmpA (Rv0226c) — requalified: hypothetical protein Rv0228 (Rv0228) — requalified: acyltransferase Rv0229c (Rv0229c) — family_assigned: PIN domain nuclease php (Rv0230c) — requalified: phosphotriesterase-related protein fadE4 (Rv0231) — family_assigned: acyl-CoA dehydrogenase family protein Rv0232 (Rv0232) — family_assigned: TetR/AcrR family transcriptional regulator nrdB (Rv0233) — requalified: R2-like ligand-binding oxidase Rv0235c (Rv0235c) — family_assigned: lipase maturation factor family protein aftD (Rv0236c) — family_assigned: DUF3367 domain-containing protein aftD Rv0238 (Rv0238) — family_assigned: TetR/AcrR family transcriptional regulator vapB24 (Rv0239) — requalified: antitoxin vapC24 (Rv0240) — family_assigned: type II toxin-antitoxin system VapC family toxin htdX (Rv0241c) — requalified: 3-hydroxyacyl-thioester dehydratase HtdX fabG4 (Rv0242c) — requalified: 3-oxoacyl-ACP reductase fadA2 (Rv0243) — requalified: acetyl-CoA C-acetyltransferase fadE5 (Rv0244c) — requalified: acyl-CoA dehydrogenase Rv0245 (Rv0245) — family_assigned: flavin reductase family protein Rv0246 (Rv0246) — family_assigned: integral membrane protein Rv0247c (Rv0247c) — family_assigned: succinate dehydrogenase/fumarate reductase iron-sulfur subun Rv0248c (Rv0248c) — family_assigned: fumarate reductase/succinate dehydrogenase flavoprotein subu Rv0249c (Rv0249c) — family_assigned: succinate dehydrogenase membrane anchor subunit Rv0250c (Rv0250c) — family_assigned: hypothetical protein hsp (Rv0251c) — requalified: stress-responsive chaperone Acr2 nirB (Rv0252) — family_assigned: nitrite reductase large subunit NirB nirD (Rv0253) — family_assigned: nitrite reductase small subunit NirD cobU (Rv0254c) — requalified: bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph Rv0258c (Rv0258c) — requalified: hypothetical protein Rv0259c (Rv0259c) — family_assigned: sirohydrochlorin chelatase Rv0260c (Rv0260c) — requalified: uroporphyrinogen-III synthase narK3 (Rv0261c) — requalified: nitrate/nitrite transporter Rv0263c (Rv0263c) — family_assigned: 5-oxoprolinase/urea amidolyase family protein Rv0264c (Rv0264c) — family_assigned: allophanate hydrolase subunit 1 oplA (Rv0266c) — family_assigned: hydantoinase B/oxoprolinase family protein narU (Rv0267) — family_assigned: NarK family nitrate/nitrite MFS transporter Rv0269c (Rv0269c) — requalified: DNA polymerase domain-containing protein fadD2 (Rv0270) — requalified: long-chain-fatty-acid--CoA ligase FadD2 fadE6 (Rv0271c) — family_assigned: acyl-CoA dehydrogenase family protein Rv0272c (Rv0272c) — family_assigned: alpha/beta hydrolase Rv0273c (Rv0273c) — family_assigned: TetR/AcrR family transcriptional regulator Rv0274 (Rv0274) — family_assigned: VOC family protein Rv0276 (Rv0276) — family_assigned: oxygenase MpaB family protein vapC25 (Rv0277c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv0281 (Rv0281) — requalified: class I SAM-dependent methyltransferase eccB3 (Rv0283) — family_assigned: type VII secretion system ESX-3 subunit EccB3 eccC3 (Rv0284) — family_assigned: type VII secretion system ESX-3 FtsK/SpoIIIE family ATPase E esxG (Rv0287) — requalified: type VII secretion system protein EsxG esxH (Rv0288) — requalified: type VII secretion system effector EsxH espG3 (Rv0289) — requalified: type VII secretion system ESX-3 associated protein EspG3 eccD3 (Rv0290) — family_assigned: type VII secretion system ESX-3 subunit EccD3 mycP3 (Rv0291) — requalified: type VII secretion system ESX-3 serine protease mycosin MycP eccE3 (Rv0292) — family_assigned: type VII secretion system ESX-3 subunit EccE3 Rv0293c (Rv0293c) — requalified: alpha/beta fold hydrolase tam (Rv0294) — requalified: trans-aconitate 2-methyltransferase Rv0295c (Rv0295c) — family_assigned: Stf0 family sulfotransferase Rv0298 (Rv0298) — family_assigned: ribbon-helix-helix protein%2C CopG family Rv0299 (Rv0299) — requalified: toxin-antitoxin system toxin vapB2 (Rv0300) — requalified: type II toxin-antitoxin system antitoxin VapB2 vapC2 (Rv0301) — family_assigned: PIN domain nuclease Rv0302 (Rv0302) — family_assigned: TetR/AcrR family transcriptional regulator Rv0303 (Rv0303) — requalified: protochlorophyllide reductase 238 kb 265 kb 292 kb 318 kb 344 kb 371 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.