MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 12 742–172 742 bp (160 000 bp)
+ strand − strand Rv0010c (Rv0010c) — family_assigned: PH domain-containing protein crgA (Rv0011c) — requalified: cell division protein CrgA pknB (Rv0014c) — family_assigned: Stk1 family PASTA domain-containing Ser/Thr kinase pknA (Rv0015c) — requalified: serine/threonine protein kinase PknA pbpA (Rv0016c) — requalified: D%2CD-transpeptidase PbpA rodA (Rv0017c) — requalified: cell shape-determining peptidoglycan glycosyltransferase Rod fhaB (Rv0019c) — family_assigned: FHA domain-containing protein fhaA (Rv0020c) — requalified: cell division-associated protein FhaA Rv0021c (Rv0021c) — family_assigned: nitronate monooxygenase family protein whiB5 (Rv0022c) — family_assigned: transcriptional regulator WhiB5 Rv0023 (Rv0023) — family_assigned: helix-turn-helix transcriptional regulator Rv0024 (Rv0024) — family_assigned: C40 family peptidase Rv0025 (Rv0025) — dark: DUF4226 domain-containing protein Rv0027 (Rv0027) — family_assigned: ESX-1 secretion-associated protein Rv0028 (Rv0028) — family_assigned: DUF2694 domain-containing protein Rv0029 (Rv0029) — dark: DUF5631 domain-containing protein Rv0030 (Rv0030) — family_assigned: DUF2710 domain-containing protein bioF2 (Rv0032) — family_assigned: pyridoxal phosphate-dependent aminotransferase family protei acpA (Rv0033) — requalified: acyl carrier protein Rv0034 (Rv0034) — family_assigned: nuclear transport factor 2 family protein Rv0036c (Rv0036c) — family_assigned: TIGR03084 family metal-binding protein Rv0037c (Rv0037c) — requalified: MFS transporter Rv0038 (Rv0038) — family_assigned: YqgE/AlgH family protein Rv0039c (Rv0039c) — dark: hypothetical protein mtc28 (Rv0040c) — family_assigned: LpqN/LpqT family lipoprotein leuS (Rv0041) — requalified: leucine--tRNA ligase Rv0043c (Rv0043c) — family_assigned: GntR family transcriptional regulator Rv0044c (Rv0044c) — requalified: LLM class F420-dependent oxidoreductase Rv0045c (Rv0045c) — family_assigned: alpha/beta hydrolase ino1 (Rv0046c) — requalified: inositol-3-phosphate synthase Rv0047c (Rv0047c) — family_assigned: PadR family transcriptional regulator Rv0048c (Rv0048c) — family_assigned: DUF1707 domain-containing protein Rv0051 (Rv0051) — family_assigned: glycosyltransferase family 87 protein rpsF (Rv0053) — requalified: 30S ribosomal protein S6 ssb (Rv0054) — family_assigned: single-stranded DNA-binding protein rplI (Rv0056) — requalified: 50S ribosomal protein L9 Rv0057 (Rv0057) — dark: hypothetical protein dnaB (Rv0058) — requalified: replicative DNA helicase darT (Rv0059) — requalified: toxin-antitoxin system toxin DarT darG (Rv0060) — requalified: toxin-antitoxin system antitoxin DNA ADP-ribosyl glycohydrol Rv0063 (Rv0063) — requalified: FAD-binding oxidoreductase Rv0064 (Rv0064) — family_assigned: UPF0182 family protein vapC1 (Rv0065) — requalified: type II toxin-antitoxin system ribonuclease VapC1 icd2 (Rv0066c) — requalified: NADP-dependent isocitrate dehydrogenase Rv0067c (Rv0067c) — family_assigned: helix-turn-helix domain-containing protein Rv0068 (Rv0068) — family_assigned: SDR family NAD(P)-dependent oxidoreductase sdaA (Rv0069c) — requalified: L-serine ammonia-lyase glyA2 (Rv0070c) — requalified: serine hydroxymethyltransferase Rv0071 (Rv0071) — family_assigned: reverse transcriptase domain-containing protein Rv0072 (Rv0072) — family_assigned: FtsX-like permease family protein Rv0073 (Rv0073) — family_assigned: ATP-binding cassette domain-containing protein Rv0074 (Rv0074) — family_assigned: amidohydrolase family protein Rv0075 (Rv0075) — family_assigned: MalY/PatB family protein Rv0077c (Rv0077c) — family_assigned: alpha/beta hydrolase Rv0078 (Rv0078) — family_assigned: TetR/AcrR family transcriptional regulator Rv0079 (Rv0079) — requalified: dormancy-associated translation inhibitor Rv0080 (Rv0080) — family_assigned: pyridoxamine 5'-phosphate oxidase family protein Rv0081 (Rv0081) — family_assigned: lsr2/espR transcriptional regulator Rv0082 (Rv0082) — family_assigned: NADH-quinone oxidoreductase subunit B family protein Rv0083 (Rv0083) — requalified: oxidoreductase hycD (Rv0084) — family_assigned: respiratory chain complex I subunit 1 family protein hycP (Rv0085) — family_assigned: hypothetical protein hycQ (Rv0086) — requalified: hydrogenase HycQ hycE (Rv0087) — family_assigned: NADH-quinone oxidoreductase subunit C Rv0090 (Rv0090) — dark: DUF2127 domain-containing protein mtn (Rv0091) — requalified: 5'-methylthioadenosine/adenosylhomocysteine nucleosidase ctpA (Rv0092) — requalified: heavy metal translocating P-type ATPase Rv0097 (Rv0097) — family_assigned: TauD/TfdA family dioxygenase fcoT (Rv0098) — requalified: fatty acyl CoA thioesterase FcoT Rv0100 (Rv0100) — requalified: acyl carrier protein nrp (Rv0101) — requalified: non-ribosomal peptide synthetase Nrp nrp Rv0102 (Rv0102) — requalified: cytochrome c oxidase assembly protein ctpB (Rv0103c) — requalified: cation-translocating P-type ATPase Rv0104 (Rv0104) — family_assigned: cyclic nucleotide-binding domain-containing protein Rv0106 (Rv0106) — family_assigned: GTP-binding protein Rv0111 (Rv0111) — family_assigned: acyltransferase family protein gca (Rv0112) — requalified: GDP-mannose 4%2C6-dehydratase gmhA (Rv0113) — requalified: D-sedoheptulose 7-phosphate isomerase gmhB (Rv0114) — requalified: D-glycero-alpha-D-manno-heptose-1%2C7-bisphosphate 7-phospha hddA (Rv0115) — requalified: D-alpha-D-heptose-7-phosphate kinase HddA ldtA (Rv0116c) — requalified: L%2CD-transpeptidase LdtMt1 oxyS (Rv0117) — family_assigned: LysR family transcriptional regulator OxyS oxcA (Rv0118c) — requalified: oxalyl-CoA decarboxylase fadD7 (Rv0119) — family_assigned: FadD7 family fatty acid--CoA ligase fusA2 (Rv0120c) — family_assigned: elongation factor G-like protein EF-G2 Rv0121c (Rv0121c) — family_assigned: TIGR03668 family PPOX class F420-dependent oxidoreductase Rv0122 (Rv0122) — family_assigned: hypothetical protein Rv0123 (Rv0123) — family_assigned: DNA-binding protein pepA (Rv0125) — family_assigned: S1C family serine protease treS (Rv0126) — requalified: maltose alpha-D-glucosyltransferase mak (Rv0127) — requalified: maltokinase Rv0128 (Rv0128) — family_assigned: YoaK family protein htdZ (Rv0130) — requalified: 3-hydroxyacyl-thioester dehydratase HtdZ fgd2 (Rv0132c) — requalified: F420-dependent hydroxymycolic acid dehydrogenase Rv0133 (Rv0133) — family_assigned: GNAT family N-acetyltransferase ephF (Rv0134) — family_assigned: alpha/beta hydrolase Rv0135c (Rv0135c) — family_assigned: helix-turn-helix domain-containing protein cyp138 (Rv0136) — requalified: cytochrome P450 msrA (Rv0137c) — requalified: peptide-methionine (S)-S-oxide reductase MsrA Rv0138 (Rv0138) — family_assigned: nuclear transport factor 2 family protein Rv0139 (Rv0139) — family_assigned: NAD-dependent epimerase/dehydratase family protein Rv0140 (Rv0140) — family_assigned: DUF427 domain-containing protein Rv0141c (Rv0141c) — family_assigned: nuclear transport factor 2 family protein Rv0142 (Rv0142) — requalified: DNA-3-methyladenine glycosylase Rv0143c (Rv0143c) — requalified: chloride channel protein Rv0145 (Rv0145) — requalified: class I SAM-dependent methyltransferase Rv0146 (Rv0146) — requalified: class I SAM-dependent methyltransferase 26 kb 53 kb 80 kb 106 kb 132 kb 159 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.