MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 094 502–3 254 502 bp (160 000 bp)
+ strand − strand hsdS (Rv2761c) — family_assigned: restriction endonuclease subunit S Rv2762c (Rv2762c) — family_assigned: winged helix-turn-helix domain-containing protein qcrA (Rv2195) — requalified: hypothetical protein dfrA (Rv2763c) — requalified: dihydrofolate reductase Rv2765 (Rv2765) — family_assigned: dienelactone hydrolase family protein Rv2767c (Rv2767c) — family_assigned: hypothetical protein Rv2771c (Rv2771c) — family_assigned: flavodoxin family protein Rv2772c (Rv2772c) — family_assigned: hypothetical protein dapB (Rv2773c) — requalified: 4-hydroxy-tetrahydrodipicolinate reductase Rv2774c (Rv2774c) — dark: hypothetical protein Rv2777c (Rv2777c) — requalified: metal-dependent hydrolase Rv2778c (Rv2778c) — family_assigned: SRPBCC family protein ald (Rv2780) — requalified: alanine dehydrogenase Rv2781c (Rv2781c) — requalified: nitronate monooxygenase pepR (Rv2782c) — family_assigned: pitrilysin family protein gpsI (Rv2783c) — requalified: polyribonucleotide nucleotidyltransferase lppU (Rv2784c) — dark: hypothetical protein Rv2787 (Rv2787) — family_assigned: AAA family ATPase sirR (Rv2788) — family_assigned: manganese-binding transcriptional regulator MntR fadE21 (Rv2789c) — family_assigned: acyl-CoA dehydrogenase family protein ltp1 (Rv2790c) — requalified: lipid-transfer protein truB (Rv2793c) — requalified: tRNA pseudouridine(55) synthase TruB pptT (Rv2794c) — requalified: 4'-phosphopantetheinyl transferase Rv2795c (Rv2795c) — requalified: metallophosphoesterase lppV (Rv2796c) — family_assigned: LppA family lipoprotein Rv2797c (Rv2797c) — family_assigned: alpha/beta hydrolase family protein Rv2798c (Rv2798c) — family_assigned: hypothetical protein Rv2800 (Rv2800) — family_assigned: CocE/NonD family hydrolase mazF9 (Rv2801c) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF9 Rv2802c (Rv2802c) — dark: DUF2293 domain-containing protein Rv2806 (Rv2806) — dark: hypothetical protein Rv2805 (Rv2805) — requalified: transposase Rv2808 (Rv2808) — requalified: hypothetical protein Rv2809 (Rv2809) — family_assigned: hypothetical protein Rv2811 (Rv2811) — family_assigned: hypothetical protein Rv2813 (Rv2813) — family_assigned: ExeA family protein cas2 (Rv2816c) — requalified: CRISPR-associated endonuclease Cas2 cas1 (Rv2817c) — requalified: CRISPR-associated endonuclease Cas1 csm5 (Rv2819c) — requalified: type III-A CRISPR-associated RAMP protein Csm5 csm4 (Rv2820c) — requalified: type III-A CRISPR-associated RAMP protein Csm4 csm3 (Rv2821c) — requalified: type III-A CRISPR-associated RAMP protein Csm3 csm2 (Rv2822c) — requalified: type III-A CRISPR-associated protein Csm2 cas10 (Rv2823c) — requalified: type III-A CRISPR-associated protein Cas10/Csm1 Rv2826c (Rv2826c) — family_assigned: nucleotidyl transferase AbiEii/AbiGii toxin family protein Rv2827c (Rv2827c) — family_assigned: type IV toxin-antitoxin system AbiEi family antitoxin Rv2828c (Rv2828c) — family_assigned: DUF1802 family protein vapC22 (Rv2829c) — family_assigned: PIN domain-containing protein vapB22 (Rv2830c) — family_assigned: type II toxin-antitoxin system prevent-host-death family ant echA16 (Rv2831) — requalified: enoyl-CoA hydratase ugpC (Rv2832c) — family_assigned: ABC transporter ATP-binding protein ugpB (Rv2833c) — family_assigned: ABC transporter substrate-binding protein ugpE (Rv2834c) — family_assigned: carbohydrate ABC transporter permease ugpA (Rv2835c) — family_assigned: sugar ABC transporter permease dinF (Rv2836c) — family_assigned: MATE family efflux transporter nrnA (Rv2837c) — requalified: bifunctional oligoribonuclease/PAP phosphatase NrnA rbfA (Rv2838c) — requalified: 30S ribosome-binding factor RbfA infB (Rv2839c) — requalified: translation initiation factor IF-2 nusA (Rv2841c) — requalified: transcription termination factor NusA rimP (Rv2842c) — requalified: ribosome maturation factor RimP Rv2843 (Rv2843) — family_assigned: hypothetical protein Rv2844 (Rv2844) — family_assigned: ferritin-like domain-containing protein proS (Rv2845c) — requalified: proline--tRNA ligase efpA (Rv2846c) — requalified: multidrug efflux MFS transporter EfpA cysG (Rv2847c) — requalified: uroporphyrinogen-III C-methyltransferase cobB (Rv2848c) — requalified: cobyrinate a%2Cc-diamide synthase Rv2850c (Rv2850c) — family_assigned: magnesium chelatase subunit D family protein Rv2851c (Rv2851c) — family_assigned: GNAT family N-acetyltransferase mqo (Rv2852c) — requalified: malate dehydrogenase (quinone) Rv2854 (Rv2854) — family_assigned: alpha/beta hydrolase nicT (Rv2856) — family_assigned: HoxN/HupN/NixA family nickel/cobalt transporter Rv2857c (Rv2857c) — requalified: 3-oxoacyl-ACP reductase Rv2859c (Rv2859c) — requalified: gamma-glutamyl-gamma-aminobutyrate hydrolase glnA4 (Rv2860c) — family_assigned: glutamine synthetase family protein Rv2862c (Rv2862c) — family_assigned: DUF1707 domain-containing protein vapC23 (Rv2863) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2864c (Rv2864c) — family_assigned: penicillin-binding protein relF (Rv2865) — requalified: type II toxin-antitoxin system antitoxin RelF relG (Rv2866) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2867c (Rv2867c) — family_assigned: GNAT family N-acetyltransferase gcpE (Rv2868c) — requalified: flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphos rip (Rv2869c) — requalified: zinc metalloprotease Rip dxr (Rv2870c) — requalified: 1-deoxy-D-xylulose-5-phosphate reductoisomerase vapB43 (Rv2871) — family_assigned: ribbon-helix-helix domain-containing protein vapC43 (Rv2872) — family_assigned: type II toxin-antitoxin system VapC family toxin mpt83 (Rv2873) — requalified: cell surface glycolipoprotein Mpt83 mpt70 (Rv2875) — family_assigned: fasciclin domain-containing protein mpt53 (Rv2878c) — requalified: protein disulfide oxidoreductase cdsA (Rv2881c) — requalified: phosphatidate cytidylyltransferase frr (Rv2882c) — requalified: ribosome recycling factor pyrH (Rv2883c) — requalified: UMP kinase Rv2887 (Rv2887) — family_assigned: MarR family transcriptional regulator amiC (Rv2888c) — requalified: amidase tsf (Rv2889c) — requalified: translation elongation factor Ts rpsB (Rv2890c) — requalified: 30S ribosomal protein S2 Rv2893 (Rv2893) — requalified: LLM class F420-dependent oxidoreductase xerC (Rv2894c) — requalified: tyrosine recombinase XerC viuB (Rv2895c) — requalified: siderophore-interacting protein dprA (Rv2896c) — requalified: DNA-processing protein DprA Rv2897c (Rv2897c) — family_assigned: YifB family Mg chelatase-like AAA ATPase Rv2898c (Rv2898c) — family_assigned: YraN family protein fdhD (Rv2899c) — requalified: formate dehydrogenase accessory sulfurtransferase FdhD fdhF (Rv2900c) — family_assigned: FdhF/YdeP family oxidoreductase Rv2901c (Rv2901c) — dark: DUF2469 domain-containing protein rnhB (Rv2902c) — requalified: ribonuclease HII lepB (Rv2903c) — requalified: signal peptidase I rplS (Rv2904c) — requalified: 50S ribosomal protein L19 lppW (Rv2905) — family_assigned: hypothetical protein trmD (Rv2906c) — requalified: tRNA (guanosine(37)-N1)-methyltransferase TrmD rimM (Rv2907c) — requalified: ribosome maturation factor RimM Rv2908c (Rv2908c) — family_assigned: RNA-binding protein rpsP (Rv2909c) — requalified: 30S ribosomal protein S16 Rv2912c (Rv2912c) — family_assigned: TetR/AcrR family transcriptional regulator Rv2913c (Rv2913c) — family_assigned: amidohydrolase family protein pknI (Rv2914c) — requalified: serine/threonine protein kinase PknI Rv2915c (Rv2915c) — family_assigned: amidohydrolase family protein ffh (Rv2916c) — requalified: signal recognition particle protein glnD (Rv2918c) — requalified: [protein-PII] uridylyltransferase glnB (Rv2919c) — family_assigned: nitrogen regulatory protein P-II amt (Rv2920c) — requalified: ammonium transporter ftsY (Rv2921c) — requalified: signal recognition particle-docking protein FtsY 3 100 kb 3 127 kb 3 154 kb 3 180 kb 3 206 kb 3 233 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.