MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 724 150–2 884 150 bp (160 000 bp)
+ strand − strand lppR (Rv2403c) — family_assigned: sensor domain-containing protein lepA (Rv2404c) — requalified: translation elongation factor 4 Rv2406c (Rv2406c) — family_assigned: CBS domain-containing protein Rv2407 (Rv2407) — family_assigned: Rv2407 family type 3 sulfatase Rv2409c (Rv2409c) — family_assigned: transglutaminase family protein Rv2410c (Rv2410c) — family_assigned: alpha-E domain-containing protein Rv2411c (Rv2411c) — requalified: circularly permuted type 2 ATP-grasp protein rpsT (Rv2412) — requalified: 30S ribosomal protein S20 Rv2413c (Rv2413c) — family_assigned: DNA polymerase III subunit delta Rv2414c (Rv2414c) — family_assigned: ComEC/Rec2 family competence protein Rv2415c (Rv2415c) — family_assigned: ComEA family DNA-binding protein Rv2417c (Rv2417c) — family_assigned: DegV family protein octT (Rv2418c) — requalified: diglucosylglycerate octanoyltransferase gpgP (Rv2419c) — requalified: glucosyl-3-phosphoglycerate phosphatase rsfS (Rv2420c) — requalified: ribosome silencing factor Rv2422 (Rv2422) — family_assigned: hypothetical protein Rv2423 (Rv2423) — requalified: class I SAM-dependent methyltransferase Rv2425c (Rv2425c) — family_assigned: VWA domain-containing protein Rv2426c (Rv2426c) — family_assigned: MoxR family ATPase proA (Rv2427c) — requalified: glutamate-5-semialdehyde dehydrogenase ahpC (Rv2428) — requalified: peroxiredoxin AhpC ahpD (Rv2429) — requalified: alkyl hydroperoxide reductase Rv2432c (Rv2432c) — dark: hypothetical protein nrtS (Rv2433c) — requalified: nitrate/nitrite transporter NrtS Rv2434c (Rv2434c) — requalified: mechanosensitive ion channel Rv2435c (Rv2435c) — family_assigned: adenylate/guanylate cyclase domain-containing protein rbsK (Rv2436) — requalified: ribokinase RbsK Rv2437 (Rv2437) — family_assigned: isoprenylcysteine carboxylmethyltransferase family protein nadE (Rv2438c) — requalified: NAD(+) synthase proB (Rv2439c) — requalified: glutamate 5-kinase obg (Rv2440c) — requalified: GTPase ObgE rpmA (Rv2441c) — requalified: 50S ribosomal protein L27 rplU (Rv2442c) — requalified: 50S ribosomal protein L21 dctA (Rv2443) — family_assigned: cation:dicarboxylase symporter family transporter rne (Rv2444c) — family_assigned: Rne/Rng family ribonuclease ndkA (Rv2445c) — requalified: nucleoside-diphosphate kinase Rv2446c (Rv2446c) — dark: DUF4233 domain-containing protein folC (Rv2447c) — requalified: bifunctional tetrahydrofolate synthase/dihydrofolate synthas Rv2449c (Rv2449c) — family_assigned: trans-acting enoyl reductase family protein rpfE (Rv2450c) — requalified: resuscitation-promoting factor protein RpfE Rv2451 (Rv2451) — dark: hypothetical protein Rv2452c (Rv2452c) — dark: hypothetical protein mobA (Rv2453c) — requalified: molybdenum cofactor guanylyltransferase Rv2454c (Rv2454c) — family_assigned: 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2455c (Rv2455c) — family_assigned: 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2456c (Rv2456c) — requalified: MFS transporter clpX (Rv2457c) — family_assigned: ATP-dependent Clp protease ATP-binding subunit ClpX mmuM (Rv2458) — requalified: homocysteine S-methyltransferase jefA (Rv2459) — requalified: multidrug efflux pump JefA clpP2 (Rv2460c) — family_assigned: ATP-dependent CLP protease proteolytic subunit ClpP2 tig (Rv2462c) — requalified: trigger factor lipP (Rv2463) — family_assigned: serine hydrolase domain-containing protein Rv2464c (Rv2464c) — family_assigned: Fpg/Nei family DNA glycosylase Rv2466c (Rv2466c) — family_assigned: Rv2466c family mycothiol-dependent reductase Rv2469c (Rv2469c) — requalified: HNH endonuclease glbO (Rv2470) — requalified: group 2 truncated hemoglobin GlbO aglA (Rv2471) — family_assigned: glycoside hydrolase family 13 protein Rv2472 (Rv2472) — dark: hypothetical protein Rv2473 (Rv2473) — dark: hypothetical protein Rv2474c (Rv2474c) — family_assigned: hypothetical protein Rv2475c (Rv2475c) — family_assigned: thioesterase family protein gdh (Rv2476c) — requalified: NAD-glutamate dehydrogenase gdh ettA (Rv2477c) — requalified: energy-dependent translational throttle protein EttA Rv2481c (Rv2481c) — family_assigned: hypothetical protein plsB2 (Rv2482c) — requalified: glycerol-3-phosphate 1-O-acyltransferase plsC (Rv2483c) — family_assigned: HAD-IB family hydrolase Rv2484c (Rv2484c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase lipQ (Rv2485c) — family_assigned: alpha/beta hydrolase echA14 (Rv2486) — requalified: enoyl-CoA hydratase Rv2489c (Rv2489c) — dark: hypothetical protein Rv2491 (Rv2491) — family_assigned: TIGR00725 family protein Rv2492 (Rv2492) — requalified: hypothetical protein vapB38 (Rv2493) — requalified: antitoxin vapC38 (Rv2494) — family_assigned: type II toxin-antitoxin system VapC family toxin bkdC (Rv2495c) — family_assigned: dihydrolipoamide acetyltransferase family protein bkdB (Rv2496c) — family_assigned: 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdA (Rv2497c) — family_assigned: pyruvate dehydrogenase (acetyl-transferring) E1 component su citE (Rv2498c) — family_assigned: citrate (pro-3S)-lyase subunit beta Rv2499c (Rv2499c) — family_assigned: MaoC family dehydratase fadE19 (Rv2500c) — family_assigned: acyl-CoA dehydrogenase family protein accA1 (Rv2501c) — family_assigned: acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alph accD1 (Rv2502c) — family_assigned: acetyl-/propionyl-CoA carboxylase subunit beta scoB (Rv2503c) — family_assigned: succinyl-CoA--3-ketoacid CoA transferase subunit B scoA (Rv2504c) — family_assigned: succinyl-CoA--3-ketoacid CoA transferase subunit A fadD35 (Rv2505c) — family_assigned: AMP-binding protein Rv2506 (Rv2506) — family_assigned: TetR/AcrR family transcriptional regulator Rv2507 (Rv2507) — family_assigned: MmpS family transport accessory protein Rv2508c (Rv2508c) — requalified: MFS transporter cmrA (Rv2509) — requalified: mycolate reductase Rv2510c (Rv2510c) — family_assigned: DUF853 domain-containing protein orn (Rv2511) — requalified: oligoribonuclease Rv2513 (Rv2513) — dark: hypothetical protein Rv2514c (Rv2514c) — family_assigned: DUF4411 family protein Rv2515c (Rv2515c) — family_assigned: XRE family transcriptional regulator Rv2516c (Rv2516c) — dark: hypothetical protein Rv2517c (Rv2517c) — dark: hypothetical protein ldtB (Rv2518c) — requalified: L%2CD-transpeptidase LdtMt2 Rv2520c (Rv2520c) — dark: DUF3618 domain-containing protein bcp (Rv2521) — requalified: thioredoxin-dependent thiol peroxidase Rv2522c (Rv2522c) — requalified: dipeptidase acpS (Rv2523c) — requalified: holo-ACP synthase fas (Rv2524c) — requalified: fatty acid synthase fas Rv2525c (Rv2525c) — family_assigned: DUF1906 domain-containing protein vapB17 (Rv2526) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC17 (Rv2527) — family_assigned: PIN domain-containing protein mrr (Rv2528c) — requalified: restriction endonuclease vapC39 (Rv2530c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv2532c (Rv2532c) — requalified: antitermination protein NusB nusB (Rv2533c) — requalified: transcription antitermination factor NusB pepQ (Rv2535c) — family_assigned: Xaa-Pro peptidase family protein Rv2536 (Rv2536) — family_assigned: B-4DMT family transporter aroD (Rv2537c) — requalified: type II 3-dehydroquinate dehydratase 2 730 kb 2 756 kb 2 782 kb 2 809 kb 2 836 kb 2 862 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.