MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 423 045–583 045 bp (160 000 bp)
+ strand − strand dnaK (Rv0350) — requalified: molecular chaperone DnaK grpE (Rv0351) — requalified: nucleotide exchange factor GrpE hspR (Rv0353) — family_assigned: heat shock transcriptional regulator HspR Rv0356c (Rv0356c) — family_assigned: PaaI family thioesterase purA (Rv0357c) — requalified: adenylosuccinate synthase Rv0358 (Rv0358) — requalified: peptidase M50 Rv0359 (Rv0359) — family_assigned: site-2 protease family protein Rv0361 (Rv0361) — family_assigned: hypothetical protein mgtE (Rv0362) — requalified: magnesium transporter fba (Rv0363c) — requalified: class II fructose-bisphosphate aldolase Rv0364 (Rv0364) — family_assigned: VTT domain-containing protein Rv0365c (Rv0365c) — family_assigned: glycoside hydrolase family 76 protein Rv0366c (Rv0366c) — family_assigned: zeta toxin family protein Rv0367c (Rv0367c) — family_assigned: hypothetical protein Rv0368c (Rv0368c) — family_assigned: VWA domain-containing protein Rv0370c (Rv0370c) — family_assigned: MoxR family ATPase Rv0371c (Rv0371c) — family_assigned: NTP transferase domain-containing protein Rv0372c (Rv0372c) — family_assigned: XdhC family protein Rv0373c (Rv0373c) — family_assigned: aerobic carbon-monoxide dehydrogenase large subunit Rv0374c (Rv0374c) — family_assigned: (2Fe-2S)-binding protein Rv0377 (Rv0377) — family_assigned: LysR family transcriptional regulator Rv0378 (Rv0378) — dark: hypothetical protein Rv0381c (Rv0381c) — dark: hypothetical protein ttfA (Rv0383c) — requalified: trehalose monomycolate transport factor TtfA Rv0385 (Rv0385) — requalified: FAD-binding oxidoreductase Rv0386 (Rv0386) — family_assigned: LuxR family transcriptional regulator purT (Rv0389) — requalified: phosphoribosylglycinamide formyltransferase 2 Rv0390 (Rv0390) — family_assigned: rhodanese-like domain-containing protein metZ (Rv0391) — requalified: O-succinylhomoserine sulfhydrylase ndhA (Rv0392c) — requalified: NAD(P)/FAD-dependent oxidoreductase Rv0394c (Rv0394c) — requalified: hyaluronidase/chondrosulfatase Rv0395 (Rv0395) — dark: hypothetical protein Rv0396 (Rv0396) — dark: hypothetical protein Rv0398c (Rv0398c) — family_assigned: hypothetical protein lpqK (Rv0399c) — family_assigned: serine hydrolase domain-containing protein fadE7 (Rv0400c) — requalified: acyl-CoA dehydrogenase Rv0401 (Rv0401) — dark: DUF3054 domain-containing protein mmpL1 (Rv0402c) — requalified: RND transporter MmpL1 mmpS1 (Rv0403c) — family_assigned: MmpS family protein fgd1 (Rv0407) — requalified: glucose-6-phosphate dehydrogenase (coenzyme-F420) pta (Rv0408) — requalified: phosphate acetyltransferase ackA (Rv0409) — requalified: acetate kinase pknG (Rv0410c) — requalified: serine/threonine protein kinase PknG glnH (Rv0411c) — family_assigned: glutamate ABC transporter substrate-binding protein glnX (Rv0412c) — requalified: protein kinase G-activating protein GlnX thiE (Rv0414c) — requalified: thiamine phosphate synthase thiO (Rv0415) — requalified: glycine oxidase ThiO thiS (Rv0416) — requalified: sulfur carrier protein ThiS thiG (Rv0417) — requalified: thiazole synthase lpqL (Rv0418) — family_assigned: M28 family metallopeptidase lpqM (Rv0419) — requalified: neutral zinc metallopeptidase Rv0421c (Rv0421c) — family_assigned: alpha/beta family hydrolase thiC (Rv0423c) — requalified: phosphomethylpyrimidine synthase ThiC Rv0424c (Rv0424c) — dark: hypothetical protein ctpH (Rv0425c) — requalified: cation-translocating P-type ATPase ctpH Rv0426c (Rv0426c) — dark: hypothetical protein Rv0428c (Rv0428c) — family_assigned: GNAT family N-acetyltransferase def (Rv0429c) — requalified: peptide deformylase napA (Rv0430) — requalified: DUF3263 domain-containing protein sodC (Rv0432) — family_assigned: superoxide dismutase family protein Rv0433 (Rv0433) — requalified: glutamate--cysteine ligase Rv0434 (Rv0434) — family_assigned: LON peptidase substrate-binding domain-containing protein Rv0435c (Rv0435c) — family_assigned: AAA family ATPase pssA (Rv0436c) — requalified: CDP-diacylglycerol--serine O-phosphatidyltransferase psd (Rv0437c) — requalified: phosphatidylserine decarboxylase Rv0439c (Rv0439c) — family_assigned: SDR family NAD(P)-dependent oxidoreductase groEL2 (Rv0440) — requalified: chaperonin GroEL Rv0441c (Rv0441c) — family_assigned: pyridoxamine 5'-phosphate oxidase family protein Rv0443 (Rv0443) — requalified: mycothiol transferase rskA (Rv0444c) — requalified: anti-sigma-K factor RskA sigK (Rv0445c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigK Rv0446c (Rv0446c) — family_assigned: DUF1295 domain-containing protein ufaA1 (Rv0447c) — requalified: class I SAM-dependent methyltransferase Rv0449c (Rv0449c) — requalified: NAD(P)/FAD-dependent oxidoreductase mmpS4 (Rv0451c) — requalified: siderophore RND transporter accessory protein MmpS4 Rv0452 (Rv0452) — family_assigned: TetR family transcriptional regulator Rv0455c (Rv0455c) — family_assigned: DUF5078 domain-containing protein echA2 (Rv0456c) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0457c (Rv0457c) — family_assigned: prolyl oligopeptidase family protein Rv0458 (Rv0458) — family_assigned: aldehyde dehydrogenase family protein Rv0459 (Rv0459) — family_assigned: DUF779 domain-containing protein lpdC (Rv0462) — requalified: dihydrolipoyl dehydrogenase Rv0463 (Rv0463) — dark: hypothetical protein Rv0464c (Rv0464c) — family_assigned: carboxymuconolactone decarboxylase family protein ramB (Rv0465c) — family_assigned: acetate metabolism transcriptional regulator RamB Rv0466 (Rv0466) — requalified: acyl-[acyl-carrier-protein] thioesterase fadB2 (Rv0468) — requalified: 3-hydroxybutyryl-CoA dehydrogenase FadB2 Rv0471c (Rv0471c) — requalified: 1%2C4-dihydroxy-2-naphthoate prenyltransferase Rv0472c (Rv0472c) — family_assigned: TetR/AcrR family transcriptional regulator Rv0473 (Rv0473) — dark: DUF445 domain-containing protein Rv0474 (Rv0474) — family_assigned: helix-turn-helix transcriptional regulator hbhA (Rv0475) — requalified: heparin-binding hemagglutinin HbhA Rv0477 (Rv0477) — dark: DUF2599 domain-containing protein deoC (Rv0478) — requalified: deoxyribose-phosphate aldolase Rv0479c (Rv0479c) — family_assigned: DUF2993 domain-containing protein Rv0480c (Rv0480c) — family_assigned: carbon-nitrogen hydrolase family protein Rv0481c (Rv0481c) — family_assigned: DUF2505 domain-containing protein murB (Rv0482) — requalified: UDP-N-acetylmuramate dehydrogenase lprQ (Rv0483) — requalified: L%2CD-transpeptidase LdtMt5 Rv0484c (Rv0484c) — family_assigned: SDR family oxidoreductase Rv0485 (Rv0485) — family_assigned: transcriptional regulator mshA (Rv0486) — requalified: D-inositol-3-phosphate glycosyltransferase Rv0487 (Rv0487) — family_assigned: YbjN domain-containing protein senX3 (Rv0490) — requalified: two-component system sensor histidine kinase SenX3 424 kb 450 kb 477 kb 504 kb 530 kb 556 kb 583 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.