MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 536 161–3 696 161 bp (160 000 bp)
+ strand − strand nuoD (Rv3148) — family_assigned: NADH dehydrogenase (quinone) subunit D nuoE (Rv3149) — family_assigned: NADH-quinone oxidoreductase subunit NuoE nuoF (Rv3150) — family_assigned: NADH-quinone oxidoreductase subunit NuoF nuoG (Rv3151) — family_assigned: NADH-quinone oxidoreductase subunit G nuoH (Rv3152) — family_assigned: NADH-quinone oxidoreductase subunit NuoH nuoI (Rv3153) — family_assigned: NADH-quinone oxidoreductase subunit NuoI nuoJ (Rv3154) — family_assigned: NADH-quinone oxidoreductase subunit J nuoK (Rv3155) — family_assigned: NADH-quinone oxidoreductase subunit NuoK nuoL (Rv3156) — family_assigned: NADH-quinone oxidoreductase subunit L nuoM (Rv3157) — family_assigned: NADH-quinone oxidoreductase subunit M nuoN (Rv3158) — family_assigned: NADH-quinone oxidoreductase subunit NuoN Rv3160c (Rv3160c) — family_assigned: helix-turn-helix domain-containing protein Rv3161c (Rv3161c) — family_assigned: aromatic ring-hydroxylating dioxygenase subunit alpha Rv3162c (Rv3162c) — family_assigned: integral membrane protein Rv3163c (Rv3163c) — dark: DUF58 domain-containing protein moxR3 (Rv3164c) — family_assigned: MoxR family ATPase Rv3165c (Rv3165c) — dark: hypothetical protein Rv3166c (Rv3166c) — family_assigned: DUF4129 domain-containing protein Rv3167c (Rv3167c) — family_assigned: TetR/AcrR family transcriptional regulator Rv3168 (Rv3168) — family_assigned: phosphotransferase family protein Rv3169 (Rv3169) — family_assigned: hypothetical protein aofH (Rv3170) — family_assigned: flavin monoamine oxidase family protein Rv3173c (Rv3173c) — family_assigned: helix-turn-helix domain-containing protein Rv3174 (Rv3174) — family_assigned: SDR family oxidoreductase Rv3175 (Rv3175) — requalified: amidase Rv3177 (Rv3177) — family_assigned: alpha/beta hydrolase Rv3179 (Rv3179) — family_assigned: ATP-binding protein Rv3180c (Rv3180c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv3181c (Rv3181c) — family_assigned: type II toxin-antitoxin system Phd/YefM family antitoxin Rv3182 (Rv3182) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv3183 (Rv3183) — family_assigned: XRE family transcriptional regulator Rv3188 (Rv3188) — family_assigned: antitoxin Xre/MbcA/ParS toxin-binding domain-containing prot Rv3189 (Rv3189) — family_assigned: RES family NAD+ phosphorylase Rv3190c (Rv3190c) — dark: hypothetical protein Rv3191c (Rv3191c) — family_assigned: IS30 family transposase Rv3193c (Rv3193c) — family_assigned: UPF0182 family protein Rv3194c (Rv3194c) — family_assigned: PDZ domain-containing protein Rv3195 (Rv3195) — requalified: zinc-dependent metalloprotease Rv3197 (Rv3197) — family_assigned: AarF/ABC1/UbiB kinase family protein uvrD2 (Rv3198c) — requalified: ATP-dependent DNA helicase UvrD2 nudC (Rv3199c) — requalified: NAD(+) diphosphatase Rv3200c (Rv3200c) — family_assigned: potassium channel family protein adnB (Rv3201c) — requalified: ATP-dependent DNA helicase AdnB adnA (Rv3202c) — requalified: ATP-dependent DNA helicase AdnA Rv3204 (Rv3204) — family_assigned: MGMT family protein Rv3208 (Rv3208) — family_assigned: TetR/AcrR family transcriptional regulator Rv3209 (Rv3209) — family_assigned: MmpS family transport accessory protein Rv3210c (Rv3210c) — family_assigned: ferritin-like fold-containing protein rhlE (Rv3211) — requalified: DEAD/DEAH box helicase Rv3212 (Rv3212) — family_assigned: hypothetical protein Rv3213c (Rv3213c) — family_assigned: AAA family ATPase entC (Rv3215) — requalified: isochorismate synthase Rv3217c (Rv3217c) — dark: hypothetical protein Rv3218 (Rv3218) — family_assigned: diacylglycerol kinase family lipid kinase Rv3220c (Rv3220c) — family_assigned: histidine kinase N-terminal domain-containing protein TB7.3 (Rv3221c) — requalified: biotin/lipoyl-binding carrier protein Rv3222c (Rv3222c) — family_assigned: hypothetical protein sigH (Rv3223c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigH Rv3224 (Rv3224) — requalified: NAD(P)-dependent oxidoreductase Rv3225c (Rv3225c) — family_assigned: bifunctional GNAT family N-acetyltransferase/aminoglycoside Rv3226c (Rv3226c) — requalified: SOS response-associated peptidase aroA (Rv3227) — requalified: 3-phosphoshikimate 1-carboxyvinyltransferase rsgA (Rv3228) — family_assigned: ribosome small subunit-dependent GTPase A Rv3230c (Rv3230c) — requalified: NADPH oxidoreductase Rv3231c (Rv3231c) — family_assigned: hypothetical protein Rv3237c (Rv3237c) — family_assigned: cation:proton antiporter regulatory subunit Rv3238c (Rv3238c) — family_assigned: isoprenylcysteine carboxylmethyltransferase family protein Rv3239c (Rv3239c) — requalified: MFS transporter raiA (Rv3241c) — requalified: ribosome-associated translation inhibitor RaiA Rv3242c (Rv3242c) — family_assigned: ComF family protein Rv3243c (Rv3243c) — family_assigned: LmeA family phospholipid-binding protein lpqB (Rv3244c) — requalified: MtrAB system accessory lipoprotein LpqB mtrB (Rv3245c) — requalified: two-component system sensor histidine kinase MtrB mtrA (Rv3246c) — requalified: two-component system response regulator MtrA tmk (Rv3247c) — requalified: dTMP kinase sahH (Rv3248c) — requalified: adenosylhomocysteinase Rv3249c (Rv3249c) — family_assigned: TetR family transcriptional regulator rubB (Rv3250c) — requalified: rubredoxin RubB rubA (Rv3251c) — requalified: rubredoxin alkB (Rv3252c) — requalified: alkane 1-monooxygenase Rv3253c (Rv3253c) — requalified: amino acid permease Rv3254 (Rv3254) — requalified: oxidoreductase manA (Rv3255c) — requalified: mannose-6-phosphate isomerase%2C class I Rv3256c (Rv3256c) — requalified: TobH protein pmmA (Rv3257c) — requalified: phosphomannomutase/phosphoglucomutase Rv3259 (Rv3259) — family_assigned: metallopeptidase family protein fbiA (Rv3261) — requalified: 2-phospho-L-lactate transferase fbiB (Rv3262) — requalified: coenzyme F420-0:L-glutamate ligase Rv3263 (Rv3263) — requalified: class I SAM-dependent methyltransferase rmlD (Rv3266c) — requalified: dTDP-4-dehydrorhamnose reductase lcp1 (Rv3267) — requalified: phosphotransferase Lcp1 Rv3269 (Rv3269) — family_assigned: DUF1490 family protein ctpC (Rv3270) — requalified: manganese-exporting P-type ATPase CtpC Rv3271c (Rv3271c) — requalified: cation transporter Rv3272 (Rv3272) — requalified: CoA transferase fadE25 (Rv3274c) — requalified: acyl-CoA dehydrogenase purE (Rv3275c) — requalified: 5-(carboxyamino)imidazole ribonucleotide mutase purK (Rv3276c) — requalified: 5-(carboxyamino)imidazole ribonucleotide synthase Rv3278c (Rv3278c) — family_assigned: PH domain-containing protein birA (Rv3279c) — requalified: biotin--[acetyl-CoA-carboxylase] ligase accD5 (Rv3280) — family_assigned: acyl-CoA carboxylase subunit beta accE5 (Rv3281) — family_assigned: acyl-CoA carboxylase subunit epsilon Rv3282 (Rv3282) — requalified: nucleoside triphosphate pyrophosphatase sseA (Rv3283) — requalified: sulfurtransferase Rv3284 (Rv3284) — family_assigned: SufE family protein accA3 (Rv3285) — family_assigned: acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alph sigF (Rv3286c) — requalified: RNA polymerase sigma factor SigF rsbW (Rv3287c) — requalified: anti-sigma B factor RsbW Rv3289c (Rv3289c) — dark: hypothetical protein lat (Rv3290c) — requalified: L-lysine 6-transaminase lrpA (Rv3291c) — family_assigned: transcriptional regulator LrpA Rv3292 (Rv3292) — family_assigned: VOC family protein 3 551 kb 3 578 kb 3 604 kb 3 630 kb 3 657 kb 3 684 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.