MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

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+ strand − strand Rv1977 (Rv1977) — family_assigned: M48 family metallopeptidase Rv1978 (Rv1978) — requalified: class I SAM-dependent methyltransferase Rv1979c (Rv1979c) — family_assigned: APC family permease mpt64 (Rv1980c) — requalified: immunoprotective protein Mpt64 vapC36 (Rv1982c) — family_assigned: type II toxin-antitoxin system VapC family toxin cfp21 (Rv1984c) — requalified: cutinase Cfp21 Rv1985c (Rv1985c) — family_assigned: ArgP/LysG family DNA-binding transcriptional regulator lysE (Rv1986) — requalified: L-lysine exporter Rv1987 (Rv1987) — family_assigned: cellulose-binding protein Rv1989c (Rv1989c) — family_assigned: RES family NAD+ phosphorylase Rv1990c (Rv1990c) — family_assigned: antitoxin Xre/MbcA/ParS toxin-binding domain-containing prot mazF6 (Rv1991c) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF6 ctpG (Rv1992c) — requalified: cation transporter ATPase CptG Rv1993c (Rv1993c) — family_assigned: DUF1490 family protein cmtR (Rv1994c) — family_assigned: Cd(II)/Pb(II)-sensing metalloregulatory transcriptional regu Rv1995 (Rv1995) — family_assigned: hemerythrin domain-containing protein Rv1996 (Rv1996) — requalified: universal stress protein ctpF (Rv1997) — requalified: cation-transporting P-type ATPase Rv1998c (Rv1998c) — family_assigned: isocitrate lyase/phosphoenolpyruvate mutase family protein Rv1999c (Rv1999c) — family_assigned: APC family permease Rv2000 (Rv2000) — family_assigned: FAD/NAD(P)-binding protein Rv2001 (Rv2001) — requalified: acyl-[acyl-carrier-protein] thioesterase fabG3 (Rv2002) — family_assigned: SDR family oxidoreductase Rv2004c (Rv2004c) — family_assigned: AAA family ATPase Rv2005c (Rv2005c) — requalified: universal stress protein fdxA (Rv2007c) — family_assigned: ferredoxin family protein vapC15 (Rv2010) — family_assigned: PIN domain nuclease Rv2011c (Rv2011c) — family_assigned: MarR family winged helix-turn-helix transcriptional regulato Rv2015c (Rv2015c) — requalified: HNH endonuclease signature motif containing protein Rv2016 (Rv2016) — dark: hypothetical protein Rv2017 (Rv2017) — family_assigned: ImmA/IrrE family metallo-endopeptidase Rv2018 (Rv2018) — family_assigned: DUF433 domain-containing protein Rv2019 (Rv2019) — family_assigned: hypothetical protein Rv2021c (Rv2021c) — family_assigned: XRE family transcriptional regulator Rv2022c (Rv2022c) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv2023c (Rv2023c) — dark: hypothetical protein Rv2025c (Rv2025c) — family_assigned: cation diffusion facilitator family transporter Rv2026c (Rv2026c) — requalified: universal stress protein dosT (Rv2027c) — requalified: two-component system sensor histidine kinase DosT Rv2028c (Rv2028c) — requalified: universal stress protein pfkB (Rv2029c) — family_assigned: 1-phosphofructokinase family hexose kinase Rv2030c (Rv2030c) — family_assigned: erythromycin esterase family protein hspX (Rv2031c) — requalified: alpha-crystallin HspX acg (Rv2032) — family_assigned: FMN-binding protein Acg Rv2033c (Rv2033c) — family_assigned: DUF3097 domain-containing protein Rv2034 (Rv2034) — family_assigned: metalloregulator ArsR/SmtB family transcription factor Rv2035 (Rv2035) — family_assigned: SRPBCC family protein Rv2036 (Rv2036) — family_assigned: maleylpyruvate isomerase family mycothiol-dependent enzyme Rv2037c (Rv2037c) — family_assigned: patatin-like phospholipase family protein ugpC (Rv2038c) — family_assigned: sn-glycerol-3-phosphate ABC transporter ATP-binding protein Rv2039c (Rv2039c) — family_assigned: carbohydrate ABC transporter permease Rv2040c (Rv2040c) — family_assigned: sugar ABC transporter permease Rv2041c (Rv2041c) — family_assigned: sugar ABC transporter substrate-binding protein Rv2042c (Rv2042c) — family_assigned: ketosteroid isomerase family protein pncA (Rv2043c) — requalified: pyrazinamidase PncA lppI (Rv2046) — family_assigned: hypothetical protein Rv2047c (Rv2047c) — family_assigned: sugar epimerase family protein pks12 (Rv2048c) — requalified: type I polyketide synthase pks12 rbpA (Rv2050) — family_assigned: RNA polymerase-binding protein RbpA ppm1 (Rv2051c) — requalified: apolipoprotein N-acyltransferase Rv2052c (Rv2052c) — requalified: amidohydrolase fxsA (Rv2053c) — family_assigned: FxsA family protein Rv2054 (Rv2054) — family_assigned: dienelactone hydrolase family protein rpsR2 (Rv2055c) — requalified: 30S ribosomal protein S18 rpsN2 (Rv2056c) — requalified: 30S ribosomal protein S14 rpmB2 (Rv2058c) — requalified: 50S ribosomal protein L28 Rv2061c (Rv2061c) — requalified: PPOX class F420-dependent oxidoreductase cobN (Rv2062c) — family_assigned: cobaltochelatase subunit CobN cobG (Rv2064) — requalified: precorrin-3B synthase cobH (Rv2065) — requalified: precorrin-8X methylmutase cobIJ (Rv2066) — requalified: precorrin-2 C(20)-methyltransferase Rv2067c (Rv2067c) — requalified: class I SAM-dependent methyltransferase sigC (Rv2069) — requalified: RNA polymerase sigma factor SigC cobK (Rv2070c) — requalified: cobalt-precorrin-6A reductase cobM (Rv2071c) — requalified: precorrin-4 C(11)-methyltransferase cobL (Rv2072c) — requalified: bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cob Rv2073c (Rv2073c) — family_assigned: SDR family NAD(P)-dependent oxidoreductase Rv2074 (Rv2074) — requalified: F420-dependent biliverdin reductase Rv2075c (Rv2075c) — family_assigned: hypothetical protein Rv2077c (Rv2077c) — dark: hypothetical protein Rv2078 (Rv2078) — family_assigned: DUF2563 family protein Rv2079 (Rv2079) — family_assigned: alpha/beta hydrolase lppJ (Rv2080) — family_assigned: hypothetical protein Rv2081c (Rv2081c) — dark: hypothetical protein Rv2082 (Rv2082) — dark: DUF5631 domain-containing protein Rv2083 (Rv2083) — dark: hypothetical protein Rv2084 (Rv2084) — dark: hypothetical protein pknJ (Rv2088) — requalified: serine/threonine protein kinase PknJ pepE (Rv2089c) — family_assigned: Xaa-Pro peptidase family protein Rv2091c (Rv2091c) — family_assigned: DUF4333 domain-containing protein helY (Rv2092c) — requalified: RNA helicase tatC (Rv2093c) — family_assigned: twin-arginine translocase subunit TatC tatA (Rv2094c) — family_assigned: Sec-independent protein translocase subunit TatA pafC (Rv2095c) — family_assigned: YafY family protein pafB (Rv2096c) — family_assigned: YafY family protein pafA (Rv2097c) — requalified: Pup--protein ligase helZ (Rv2101) — requalified: DEAD/DEAH box helicase vapC37 (Rv2103c) — family_assigned: type II toxin-antitoxin system VapC family toxin vapB37 (Rv2104c) — requalified: antitoxin prcA (Rv2109c) — family_assigned: proteasome subunit alpha prcB (Rv2110c) — family_assigned: proteasome subunit beta Rv2113 (Rv2113) — family_assigned: integral membrane protein 2 252 kb 2 279 kb 2 306 kb 2 332 kb 2 358 kb 2 385 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.