MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 876 846–4 036 846 bp (160 000 bp)
+ strand − strand gadB (Rv3432c) — requalified: glutamate decarboxylase Rv3433c (Rv3433c) — requalified: NAD(P)H-hydrate dehydratase Rv3434c (Rv3434c) — family_assigned: rhomboid-like protein Rv3435c (Rv3435c) — family_assigned: DUF4436 domain-containing protein glmS (Rv3436c) — requalified: glutamine--fructose-6-phosphate transaminase (isomerizing) Rv3437 (Rv3437) — dark: DUF2510 domain-containing protein Rv3438 (Rv3438) — family_assigned: alpha/beta hydrolase Rv3439c (Rv3439c) — family_assigned: hypothetical protein Rv3440c (Rv3440c) — family_assigned: hypothetical protein mrsA (Rv3441c) — requalified: phosphoglucosamine mutase rpsI (Rv3442c) — requalified: 30S ribosomal protein S9 rplM (Rv3443c) — requalified: 50S ribosomal protein L13 esxT (Rv3444c) — family_assigned: WXG100 family type VII secretion target esxU (Rv3445c) — requalified: type VII secretion system ESX-4 protein EsxU Rv3446c (Rv3446c) — family_assigned: type VII secretion-associated protein eccC4 (Rv3447c) — family_assigned: type VII secretion system ESX-4 FtsK/SpoIIIE family ATPase E eccD4 (Rv3448) — family_assigned: type VII secretion system ESX-4 subunit EccD4 mycP4 (Rv3449) — requalified: type VII secretion system ESX-4 serine protease mycosin MycP eccB4 (Rv3450c) — family_assigned: type VII secretion system ESX-4 subunit EccB4 cut3 (Rv3451) — family_assigned: cutinase family protein cut4 (Rv3452) — requalified: cutinase Cut4 rplQ (Rv3456c) — requalified: 50S ribosomal protein L17 rpoA (Rv3457c) — family_assigned: DNA-directed RNA polymerase subunit alpha rpsD (Rv3458c) — requalified: 30S ribosomal protein S4 rpsK (Rv3459c) — requalified: 30S ribosomal protein S11 rpsM (Rv3460c) — requalified: 30S ribosomal protein S13 rpmJ (Rv3461c) — requalified: 50S ribosomal protein L36 Rv3463 (Rv3463) — requalified: LLM class F420-dependent oxidoreductase rmlB (Rv3464) — requalified: dTDP-glucose 4%2C6-dehydratase rmlC (Rv3465) — requalified: dTDP-4-dehydrorhamnose 3%2C5-epimerase mhpE (Rv3469c) — requalified: 4-hydroxy-2-oxovalerate aldolase ilvB2 (Rv3470c) — family_assigned: thiamine pyrophosphate-binding protein Rv3472 (Rv3472) — family_assigned: nuclear transport factor 2 family protein Rv3480c (Rv3480c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase Rv3481c (Rv3481c) — family_assigned: GAP family protein Rv3482c (Rv3482c) — dark: DUF2510 domain-containing protein Rv3483c (Rv3483c) — family_assigned: LppP/LprE family lipoprotein cpsA (Rv3484) — family_assigned: LCP family protein Rv3486 (Rv3486) — family_assigned: DoxX family protein Rv3488 (Rv3488) — family_assigned: PadR family transcriptional regulator Rv3489 (Rv3489) — family_assigned: hypothetical protein otsA (Rv3490) — requalified: trehalose-6-phosphate synthase Rv3491 (Rv3491) — family_assigned: hypothetical protein Rv3492c (Rv3492c) — requalified: Mce associated protein Rv3493c (Rv3493c) — requalified: mammalian cell entry protein mce4F (Rv3494c) — family_assigned: virulence factor Mce family protein lprN (Rv3495c) — family_assigned: Mce family lipoprotein LprN mce4D (Rv3496c) — family_assigned: virulence factor Mce family protein mce4C (Rv3497c) — family_assigned: virulence factor Mce family protein mce4B (Rv3498c) — family_assigned: virulence factor Mce family protein yrbE4B (Rv3500c) — family_assigned: ABC transporter permease yrbE4A (Rv3501c) — family_assigned: ABC transporter permease Rv3502c (Rv3502c) — requalified: 3-oxoacyl-ACP reductase fdxD (Rv3503c) — requalified: ferredoxin fadE26 (Rv3504) — requalified: acyl-CoA dehydrogenase fadE27 (Rv3505) — family_assigned: acyl-CoA dehydrogenase family protein fadD17 (Rv3506) — requalified: long-chain-fatty-acid--CoA ligase FadD17 ilvX (Rv3509c) — family_assigned: acetolactate synthase large subunit Rv3510c (Rv3510c) — family_assigned: amidohydrolase family protein echA19 (Rv3516) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv3517 (Rv3517) — family_assigned: hypothetical protein cyp142 (Rv3518c) — requalified: steroid C26-monooxygenase Cyp142 Rv3519 (Rv3519) — family_assigned: acetoacetate decarboxylase family protein ltp4 (Rv3522) — family_assigned: thiolase domain-containing protein ltp3 (Rv3523) — family_assigned: thiolase domain-containing protein Rv3524 (Rv3524) — family_assigned: NHL repeat-containing protein Rv3525c (Rv3525c) — family_assigned: gamma carbonic anhydrase family protein kshA (Rv3526) — family_assigned: 3-ketosteroid-9-alpha-hydroxylase subunit KshA Rv3527 (Rv3527) — family_assigned: hypothetical protein Rv3528c (Rv3528c) — family_assigned: hypothetical protein Rv3529c (Rv3529c) — requalified: TLR2-mediated response inhibitor Rv3530c (Rv3530c) — family_assigned: SDR family oxidoreductase Rv3531c (Rv3531c) — family_assigned: hypothetical protein hsaF (Rv3534c) — requalified: 4-hydroxy-2-oxovalerate aldolase hsaG (Rv3535c) — requalified: acetaldehyde dehydrogenase (acetylating) hsaE (Rv3536c) — requalified: 2-keto-4-pentenoate hydratase kstD (Rv3537) — requalified: 3-oxosteroid 1-dehydrogenase ltp2 (Rv3540c) — requalified: lipid-transfer protein chsH1 (Rv3541c) — family_assigned: 3-oxo-23%2C24-bisnorchol-4%2C17(20)-dien-22-oyl-CoA hydratas chsH2 (Rv3542c) — family_assigned: 3-oxo-23%2C24-bisnorchol-4%2C17(20)-dien-22-oyl-CoA hydratas fadE29 (Rv3543c) — requalified: acyl-CoA dehydrogenase FadE29 fadE28 (Rv3544c) — requalified: acyl-CoA dehydrogenase FadE28 fadA5 (Rv3546) — requalified: steroid 3-ketoacyl-CoA thiolase ddn (Rv3547) — requalified: deazaflavin-dependent nitroreductase Ddn Rv3548c (Rv3548c) — family_assigned: SDR family oxidoreductase Rv3549c (Rv3549c) — family_assigned: SDR family oxidoreductase echA20 (Rv3550) — family_assigned: enoyl-CoA hydratase family protein Rv3551 (Rv3551) — family_assigned: CoA transferase subunit A Rv3552 (Rv3552) — family_assigned: CoA-transferase subunit beta Rv3553 (Rv3553) — requalified: nitronate monooxygenase fdxB (Rv3554) — requalified: fatty acid desaturase Rv3555c (Rv3555c) — family_assigned: DUF559 domain-containing protein fadA6 (Rv3556c) — requalified: acetyl-CoA C-acetyltransferase kstR2 (Rv3557c) — family_assigned: TetR family transcriptional regulator KstR2 Rv3559c (Rv3559c) — family_assigned: SDR family oxidoreductase fadE30 (Rv3560c) — family_assigned: acyl-CoA dehydrogenase family protein fadD3 (Rv3561) — requalified: 3-((3aS%2C4S%2C7aS)-7a-methyl-1%2C5-dioxo-octahydro-1H-inden fadE31 (Rv3562) — family_assigned: acyl-CoA dehydrogenase family protein fadE32 (Rv3563) — family_assigned: acyl-CoA dehydrogenase family protein fadE33 (Rv3564) — family_assigned: acyl-CoA dehydrogenase family protein aspB (Rv3565) — requalified: pyridoxal phosphate-dependent aminotransferase hsaB (Rv3567c) — family_assigned: flavin-dependent monooxygenase reductase subunit HsaB hsaC (Rv3568c) — requalified: iron-dependent extradiol dioxygenase HsaC hsaD (Rv3569c) — requalified: alpha/beta fold hydrolase hsaA (Rv3570c) — family_assigned: flavin-dependent monooxygenase oxygenase subunit HsaA kshB (Rv3571) — family_assigned: 3-ketosteroid-9-alpha-hydroxylase reductase subunit 3 896 kb 3 922 kb 3 948 kb 3 975 kb 4 002 kb 4 028 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.