MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

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+ strand − strand sdaA (Rv0069c) — requalified: L-serine ammonia-lyase glyA2 (Rv0070c) — requalified: serine hydroxymethyltransferase Rv0071 (Rv0071) — family_assigned: reverse transcriptase domain-containing protein Rv0072 (Rv0072) — family_assigned: FtsX-like permease family protein Rv0073 (Rv0073) — family_assigned: ATP-binding cassette domain-containing protein Rv0074 (Rv0074) — family_assigned: amidohydrolase family protein Rv0075 (Rv0075) — family_assigned: MalY/PatB family protein Rv0077c (Rv0077c) — family_assigned: alpha/beta hydrolase Rv0078 (Rv0078) — family_assigned: TetR/AcrR family transcriptional regulator Rv0079 (Rv0079) — requalified: dormancy-associated translation inhibitor Rv0080 (Rv0080) — family_assigned: pyridoxamine 5'-phosphate oxidase family protein Rv0081 (Rv0081) — family_assigned: lsr2/espR transcriptional regulator Rv0082 (Rv0082) — family_assigned: NADH-quinone oxidoreductase subunit B family protein Rv0083 (Rv0083) — requalified: oxidoreductase hycD (Rv0084) — family_assigned: respiratory chain complex I subunit 1 family protein hycP (Rv0085) — family_assigned: hypothetical protein hycQ (Rv0086) — requalified: hydrogenase HycQ hycE (Rv0087) — family_assigned: NADH-quinone oxidoreductase subunit C Rv0090 (Rv0090) — dark: DUF2127 domain-containing protein mtn (Rv0091) — requalified: 5'-methylthioadenosine/adenosylhomocysteine nucleosidase ctpA (Rv0092) — requalified: heavy metal translocating P-type ATPase Rv0097 (Rv0097) — family_assigned: TauD/TfdA family dioxygenase fcoT (Rv0098) — requalified: fatty acyl CoA thioesterase FcoT Rv0100 (Rv0100) — requalified: acyl carrier protein nrp (Rv0101) — requalified: non-ribosomal peptide synthetase Nrp nrp Rv0102 (Rv0102) — requalified: cytochrome c oxidase assembly protein ctpB (Rv0103c) — requalified: cation-translocating P-type ATPase Rv0104 (Rv0104) — family_assigned: cyclic nucleotide-binding domain-containing protein Rv0106 (Rv0106) — family_assigned: GTP-binding protein Rv0111 (Rv0111) — family_assigned: acyltransferase family protein gca (Rv0112) — requalified: GDP-mannose 4%2C6-dehydratase gmhA (Rv0113) — requalified: D-sedoheptulose 7-phosphate isomerase gmhB (Rv0114) — requalified: D-glycero-alpha-D-manno-heptose-1%2C7-bisphosphate 7-phospha hddA (Rv0115) — requalified: D-alpha-D-heptose-7-phosphate kinase HddA ldtA (Rv0116c) — requalified: L%2CD-transpeptidase LdtMt1 oxyS (Rv0117) — family_assigned: LysR family transcriptional regulator OxyS oxcA (Rv0118c) — requalified: oxalyl-CoA decarboxylase fadD7 (Rv0119) — family_assigned: FadD7 family fatty acid--CoA ligase fusA2 (Rv0120c) — family_assigned: elongation factor G-like protein EF-G2 Rv0121c (Rv0121c) — family_assigned: TIGR03668 family PPOX class F420-dependent oxidoreductase Rv0122 (Rv0122) — family_assigned: hypothetical protein Rv0123 (Rv0123) — family_assigned: DNA-binding protein pepA (Rv0125) — family_assigned: S1C family serine protease treS (Rv0126) — requalified: maltose alpha-D-glucosyltransferase mak (Rv0127) — requalified: maltokinase Rv0128 (Rv0128) — family_assigned: YoaK family protein htdZ (Rv0130) — requalified: 3-hydroxyacyl-thioester dehydratase HtdZ fgd2 (Rv0132c) — requalified: F420-dependent hydroxymycolic acid dehydrogenase Rv0133 (Rv0133) — family_assigned: GNAT family N-acetyltransferase ephF (Rv0134) — family_assigned: alpha/beta hydrolase Rv0135c (Rv0135c) — family_assigned: helix-turn-helix domain-containing protein cyp138 (Rv0136) — requalified: cytochrome P450 msrA (Rv0137c) — requalified: peptide-methionine (S)-S-oxide reductase MsrA Rv0138 (Rv0138) — family_assigned: nuclear transport factor 2 family protein Rv0139 (Rv0139) — family_assigned: NAD-dependent epimerase/dehydratase family protein Rv0140 (Rv0140) — family_assigned: DUF427 domain-containing protein Rv0141c (Rv0141c) — family_assigned: nuclear transport factor 2 family protein Rv0142 (Rv0142) — requalified: DNA-3-methyladenine glycosylase Rv0143c (Rv0143c) — requalified: chloride channel protein Rv0145 (Rv0145) — requalified: class I SAM-dependent methyltransferase Rv0146 (Rv0146) — requalified: class I SAM-dependent methyltransferase Rv0148 (Rv0148) — family_assigned: SDR family oxidoreductase Rv0149 (Rv0149) — family_assigned: NADPH:quinone oxidoreductase family protein Rv0150c (Rv0150c) — dark: hypothetical protein ptbB (Rv0153c) — requalified: tyrosine-protein phosphatase PtbB fadE2 (Rv0154c) — requalified: acyl-CoA dehydrogenase pntAa (Rv0155) — family_assigned: Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha pntAb (Rv0156) — family_assigned: NAD(P) transhydrogenase subunit alpha pntB (Rv0157) — family_assigned: NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta Rv0158 (Rv0158) — family_assigned: TetR/AcrR family transcriptional regulator Rv0161 (Rv0161) — requalified: FAD-binding oxidoreductase Rv0163 (Rv0163) — family_assigned: thioesterase family protein fadD5 (Rv0166) — requalified: fatty-acid--CoA ligase FadD5 yrbE1A (Rv0167) — family_assigned: ABC transporter permease yrbE1B (Rv0168) — family_assigned: ABC transporter permease mce1B (Rv0170) — family_assigned: virulence factor Mce family protein mce1C (Rv0171) — family_assigned: MCE family protein mce1D (Rv0172) — family_assigned: virulence factor Mce family protein lprK (Rv0173) — family_assigned: virulence factor Mce family protein mce1F (Rv0174) — family_assigned: MCE family protein Rv0175 (Rv0175) — family_assigned: hypothetical protein Rv0176 (Rv0176) — family_assigned: RDD family protein Rv0178 (Rv0178) — requalified: Mce associated membrane protein lprO (Rv0179c) — family_assigned: phosphodiester glycosidase family protein Rv0180c (Rv0180c) — family_assigned: YhgE/Pip domain-containing protein Rv0181c (Rv0181c) — family_assigned: pirin family protein sigG (Rv0182c) — family_assigned: sigma-70 family RNA polymerase sigma factor SigG Rv0183 (Rv0183) — requalified: monoacylglycerol lipase Rv0184 (Rv0184) — dark: DUF2786 domain-containing protein Rv0185 (Rv0185) — family_assigned: TIGR04338 family metallohydrolase Rv0187 (Rv0187) — requalified: O-methyltransferase Rv0188 (Rv0188) — requalified: SPW repeat protein ilvD (Rv0189c) — requalified: dihydroxy-acid dehydratase Rv0190 (Rv0190) — family_assigned: metal-sensitive transcriptional regulator Rv0191 (Rv0191) — family_assigned: Rv0191 family MFS efflux transporter Rv0193c (Rv0193c) — family_assigned: hypothetical protein Rv0194 (Rv0194) — family_assigned: ABC transporter ATP-binding protein Rv0195 (Rv0195) — requalified: response regulator transcription factor Rv0196 (Rv0196) — family_assigned: TetR/AcrR family transcriptional regulator zmp1 (Rv0198c) — requalified: zinc metalloprotease Zmp1 80 kb 106 kb 132 kb 159 kb 186 kb 212 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.