MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 460 658–3 620 658 bp (160 000 bp)
+ strand − strand Rv3076 (Rv3076) — family_assigned: SRPBCC family protein hab (Rv3078) — requalified: hydrogenase Rv3079c (Rv3079c) — requalified: LLM class F420-dependent oxidoreductase pknK (Rv3080c) — requalified: serine/threonine protein kinase PknK Rv3081 (Rv3081) — requalified: nucleotidyltransferase virS (Rv3082c) — family_assigned: AraC family transcriptional regulator Rv3083 (Rv3083) — requalified: NAD(P)/FAD-dependent oxidoreductase lipR (Rv3084) — family_assigned: alpha/beta hydrolase Rv3085 (Rv3085) — family_assigned: SDR family NAD(P)-dependent oxidoreductase adhD (Rv3086) — requalified: NDMA-dependent alcohol dehydrogenase Rv3087 (Rv3087) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase tgs4 (Rv3088) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase fadD13 (Rv3089) — requalified: long-chain-fatty-acid--CoA ligase FadD13 Rv3090 (Rv3090) — family_assigned: SPFH domain-containing protein Rv3091 (Rv3091) — family_assigned: patatin-like phospholipase family protein Rv3092c (Rv3092c) — family_assigned: DUF808 domain-containing protein Rv3093c (Rv3093c) — requalified: LLM class F420-dependent oxidoreductase Rv3094c (Rv3094c) — family_assigned: acyl-CoA dehydrogenase family protein Rv3095 (Rv3095) — family_assigned: helix-turn-helix domain-containing protein Rv3096 (Rv3096) — requalified: 1%2C4-beta-xylanase Rv3098c (Rv3098c) — dark: hypothetical protein Rv3099c (Rv3099c) — family_assigned: maleylpyruvate isomerase family mycothiol-dependent enzyme smpB (Rv3100c) — family_assigned: SsrA-binding protein SmpB ftsX (Rv3101c) — requalified: permease-like cell division protein FtsX ftsE (Rv3102c) — family_assigned: cell division ATP-binding protein FtsE Rv3103c (Rv3103c) — dark: hypothetical protein Rv3104c (Rv3104c) — family_assigned: mechanosensitive ion channel family protein fprA (Rv3106) — requalified: ferredoxin--NADP(+) reductase FprA agpS (Rv3107c) — requalified: FAD-binding oxidoreductase Rv3113 (Rv3113) — family_assigned: HAD family hydrolase Rv3114 (Rv3114) — requalified: nucleoside deaminase Rv1199c (Rv1199c) — family_assigned: IS256-like element IS1081 family transposase cysA2 (Rv0815c) — requalified: sulfurtransferase Rv0814c (Rv0814c) — family_assigned: DUF1416 domain-containing protein Rv3120 (Rv3120) — requalified: class I SAM-dependent methyltransferase cyp141 (Rv3121) — requalified: cytochrome P450 Cyp141 Rv3123 (Rv3123) — family_assigned: hypothetical protein moaR1 (Rv3124) — family_assigned: transcriptional regulator MoaR1 Rv3127 (Rv3127) — requalified: NAD(P)H nitroreductase tgs1 (Rv3130c) — requalified: diacylglycerol O-acyltransferase Rv3131 (Rv3131) — requalified: NAD(P)H nitroreductase devS (Rv3132c) — requalified: two-component system sensor histidine kinase DevS devR (Rv3133c) — requalified: two-component system response regulator DevR Rv3134c (Rv3134c) — requalified: universal stress protein hisN (Rv3137) — requalified: histidinol-phosphatase pflA (Rv3138) — requalified: AmmeMemoRadiSam system radical SAM enzyme fadE24 (Rv3139) — family_assigned: acyl-CoA dehydrogenase family protein fadE23 (Rv3140) — family_assigned: acyl-CoA dehydrogenase family protein fadB4 (Rv3141) — family_assigned: NADPH:quinone oxidoreductase family protein Rv3142c (Rv3142c) — family_assigned: DUF6188 family protein Rv3143 (Rv3143) — requalified: response regulator nuoA (Rv3145) — family_assigned: NADH-quinone oxidoreductase subunit A nuoC (Rv3147) — family_assigned: NADH-quinone oxidoreductase subunit C nuoD (Rv3148) — family_assigned: NADH dehydrogenase (quinone) subunit D nuoE (Rv3149) — family_assigned: NADH-quinone oxidoreductase subunit NuoE nuoF (Rv3150) — family_assigned: NADH-quinone oxidoreductase subunit NuoF nuoG (Rv3151) — family_assigned: NADH-quinone oxidoreductase subunit G nuoH (Rv3152) — family_assigned: NADH-quinone oxidoreductase subunit NuoH nuoI (Rv3153) — family_assigned: NADH-quinone oxidoreductase subunit NuoI nuoJ (Rv3154) — family_assigned: NADH-quinone oxidoreductase subunit J nuoK (Rv3155) — family_assigned: NADH-quinone oxidoreductase subunit NuoK nuoL (Rv3156) — family_assigned: NADH-quinone oxidoreductase subunit L nuoM (Rv3157) — family_assigned: NADH-quinone oxidoreductase subunit M nuoN (Rv3158) — family_assigned: NADH-quinone oxidoreductase subunit NuoN Rv3160c (Rv3160c) — family_assigned: helix-turn-helix domain-containing protein Rv3161c (Rv3161c) — family_assigned: aromatic ring-hydroxylating dioxygenase subunit alpha Rv3162c (Rv3162c) — family_assigned: integral membrane protein Rv3163c (Rv3163c) — dark: DUF58 domain-containing protein moxR3 (Rv3164c) — family_assigned: MoxR family ATPase Rv3165c (Rv3165c) — dark: hypothetical protein Rv3166c (Rv3166c) — family_assigned: DUF4129 domain-containing protein Rv3167c (Rv3167c) — family_assigned: TetR/AcrR family transcriptional regulator Rv3168 (Rv3168) — family_assigned: phosphotransferase family protein Rv3169 (Rv3169) — family_assigned: hypothetical protein aofH (Rv3170) — family_assigned: flavin monoamine oxidase family protein Rv3173c (Rv3173c) — family_assigned: helix-turn-helix domain-containing protein Rv3174 (Rv3174) — family_assigned: SDR family oxidoreductase Rv3175 (Rv3175) — requalified: amidase Rv3177 (Rv3177) — family_assigned: alpha/beta hydrolase Rv3179 (Rv3179) — family_assigned: ATP-binding protein Rv3180c (Rv3180c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv3181c (Rv3181c) — family_assigned: type II toxin-antitoxin system Phd/YefM family antitoxin Rv3182 (Rv3182) — family_assigned: type II toxin-antitoxin system RelE/ParE family toxin Rv3183 (Rv3183) — family_assigned: XRE family transcriptional regulator Rv3188 (Rv3188) — family_assigned: antitoxin Xre/MbcA/ParS toxin-binding domain-containing prot Rv3189 (Rv3189) — family_assigned: RES family NAD+ phosphorylase Rv3190c (Rv3190c) — dark: hypothetical protein Rv3191c (Rv3191c) — family_assigned: IS30 family transposase Rv3193c (Rv3193c) — family_assigned: UPF0182 family protein Rv3194c (Rv3194c) — family_assigned: PDZ domain-containing protein Rv3195 (Rv3195) — requalified: zinc-dependent metalloprotease Rv3197 (Rv3197) — family_assigned: AarF/ABC1/UbiB kinase family protein uvrD2 (Rv3198c) — requalified: ATP-dependent DNA helicase UvrD2 nudC (Rv3199c) — requalified: NAD(+) diphosphatase Rv3200c (Rv3200c) — family_assigned: potassium channel family protein adnB (Rv3201c) — requalified: ATP-dependent DNA helicase AdnB adnA (Rv3202c) — requalified: ATP-dependent DNA helicase AdnA Rv3204 (Rv3204) — family_assigned: MGMT family protein Rv3208 (Rv3208) — family_assigned: TetR/AcrR family transcriptional regulator Rv3209 (Rv3209) — family_assigned: MmpS family transport accessory protein Rv3210c (Rv3210c) — family_assigned: ferritin-like fold-containing protein rhlE (Rv3211) — requalified: DEAD/DEAH box helicase Rv3212 (Rv3212) — family_assigned: hypothetical protein Rv3213c (Rv3213c) — family_assigned: AAA family ATPase entC (Rv3215) — requalified: isochorismate synthase Rv3217c (Rv3217c) — dark: hypothetical protein Rv3218 (Rv3218) — family_assigned: diacylglycerol kinase family lipid kinase Rv3220c (Rv3220c) — family_assigned: histidine kinase N-terminal domain-containing protein TB7.3 (Rv3221c) — requalified: biotin/lipoyl-binding carrier protein Rv3222c (Rv3222c) — family_assigned: hypothetical protein 3 472 kb 3 498 kb 3 524 kb 3 551 kb 3 578 kb 3 604 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.