MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 3 784 815–3 944 815 bp (160 000 bp)
+ strand − strand Rv3353c (Rv3353c) — requalified: oxidoreductase Rv3354 (Rv3354) — requalified: DUF732 domain-containing protein Rv3355c (Rv3355c) — dark: DUF3017 domain-containing protein relJ (Rv3357) — requalified: type II toxin-antitoxin system antitoxin RelJ relK (Rv3358) — family_assigned: Txe/YoeB family addiction module toxin Rv3359 (Rv3359) — requalified: NADH:flavin oxidoreductase Rv3360 (Rv3360) — family_assigned: FHA domain-containing protein mfpA (Rv3361c) — requalified: pentapeptide repeat protein MfpA Rv3362c (Rv3362c) — family_assigned: ATP/GTP-binding protein Rv3363c (Rv3363c) — family_assigned: DUF742 domain-containing protein Rv3364c (Rv3364c) — requalified: serine protease inhibitor Rv3365c (Rv3365c) — requalified: sensor histidine kinase spoU (Rv3366) — requalified: tRNA (cytidine(34)-2'-O)-methyltransferase Rv3368c (Rv3368c) — family_assigned: nitroreductase family protein Rv3371 (Rv3371) — requalified: diacylglycerol O-acyltransferase otsB2 (Rv3372) — requalified: trehalose-phosphatase amiD (Rv3375) — requalified: amidase Rv3376 (Rv3376) — family_assigned: HAD family phosphatase Rv3377c (Rv3377c) — requalified: type B diterpene cyclase Rv3378c (Rv3378c) — requalified: diterpene synthase idsB (Rv3383c) — family_assigned: polyprenyl synthetase family protein vapC46 (Rv3384c) — family_assigned: type II toxin-antitoxin system VapC family toxin htdY (Rv3389c) — requalified: 3-hydroxyacyl-thioester dehydratase HtdY lpqD (Rv3390) — family_assigned: histidine phosphatase family protein acrA1 (Rv3391) — family_assigned: SDR family oxidoreductase cmaA1 (Rv3392c) — requalified: cyclopropane mycolic acid synthase CmaA1 iunH (Rv3393) — requalified: nucleoside hydrolase IunH Rv3394c (Rv3394c) — family_assigned: DNA polymerase Y family protein Rv3395c (Rv3395c) — family_assigned: hypothetical protein guaA (Rv3396c) — requalified: glutamine-hydrolyzing GMP synthase phyA (Rv3397c) — requalified: presqualene diphosphate synthase HpnD Rv3400 (Rv3400) — family_assigned: beta-phosphoglucomutase family hydrolase Rv3401 (Rv3401) — family_assigned: glycoside hydrolase family 65 protein Rv3402c (Rv3402c) — family_assigned: DegT/DnrJ/EryC1/StrS family aminotransferase Rv3403c (Rv3403c) — family_assigned: FAD/NAD(P)-binding protein Rv3404c (Rv3404c) — requalified: dTDP-4-amino-4%2C6-dideoxyglucose formyltransferase Rv3405c (Rv3405c) — family_assigned: helix-turn-helix domain-containing protein Rv3406 (Rv3406) — requalified: alpha-ketoglutarate-dependent sulfate ester dioxygenase vapC47 (Rv3408) — family_assigned: type II toxin-antitoxin system VapC family toxin choD (Rv3409c) — requalified: cholesterol oxidase guaB3 (Rv3410c) — family_assigned: GuaB3 family IMP dehydrogenase-related protein guaB2 (Rv3411c) — requalified: IMP dehydrogenase Rv3412 (Rv3412) — dark: DUF5319 domain-containing protein rsdA (Rv3413c) — requalified: anti-sigma D factor RsdA Rv3415c (Rv3415c) — family_assigned: hypothetical protein whiB3 (Rv3416) — family_assigned: redox-responsive transcriptional regulator WhiB3 groEL1 (Rv3417c) — requalified: chaperonin GroEL gcp (Rv3419c) — family_assigned: tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex rimI (Rv3420c) — requalified: ribosomal protein S18-alanine N-acetyltransferase tsaB (Rv3421c) — family_assigned: tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex tsaE (Rv3422c) — family_assigned: tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex istB (Rv3427c) — family_assigned: IS21-like element ISMt2 family helper ATPase IstB Rv3424c (Rv3424c) — dark: hypothetical protein gadB (Rv3432c) — requalified: glutamate decarboxylase Rv3433c (Rv3433c) — requalified: NAD(P)H-hydrate dehydratase Rv3434c (Rv3434c) — family_assigned: rhomboid-like protein Rv3435c (Rv3435c) — family_assigned: DUF4436 domain-containing protein glmS (Rv3436c) — requalified: glutamine--fructose-6-phosphate transaminase (isomerizing) Rv3437 (Rv3437) — dark: DUF2510 domain-containing protein Rv3438 (Rv3438) — family_assigned: alpha/beta hydrolase Rv3439c (Rv3439c) — family_assigned: hypothetical protein Rv3440c (Rv3440c) — family_assigned: hypothetical protein mrsA (Rv3441c) — requalified: phosphoglucosamine mutase rpsI (Rv3442c) — requalified: 30S ribosomal protein S9 rplM (Rv3443c) — requalified: 50S ribosomal protein L13 esxT (Rv3444c) — family_assigned: WXG100 family type VII secretion target esxU (Rv3445c) — requalified: type VII secretion system ESX-4 protein EsxU Rv3446c (Rv3446c) — family_assigned: type VII secretion-associated protein eccC4 (Rv3447c) — family_assigned: type VII secretion system ESX-4 FtsK/SpoIIIE family ATPase E eccD4 (Rv3448) — family_assigned: type VII secretion system ESX-4 subunit EccD4 mycP4 (Rv3449) — requalified: type VII secretion system ESX-4 serine protease mycosin MycP eccB4 (Rv3450c) — family_assigned: type VII secretion system ESX-4 subunit EccB4 cut3 (Rv3451) — family_assigned: cutinase family protein cut4 (Rv3452) — requalified: cutinase Cut4 rplQ (Rv3456c) — requalified: 50S ribosomal protein L17 rpoA (Rv3457c) — family_assigned: DNA-directed RNA polymerase subunit alpha rpsD (Rv3458c) — requalified: 30S ribosomal protein S4 rpsK (Rv3459c) — requalified: 30S ribosomal protein S11 rpsM (Rv3460c) — requalified: 30S ribosomal protein S13 rpmJ (Rv3461c) — requalified: 50S ribosomal protein L36 Rv3463 (Rv3463) — requalified: LLM class F420-dependent oxidoreductase rmlB (Rv3464) — requalified: dTDP-glucose 4%2C6-dehydratase rmlC (Rv3465) — requalified: dTDP-4-dehydrorhamnose 3%2C5-epimerase mhpE (Rv3469c) — requalified: 4-hydroxy-2-oxovalerate aldolase ilvB2 (Rv3470c) — family_assigned: thiamine pyrophosphate-binding protein Rv3472 (Rv3472) — family_assigned: nuclear transport factor 2 family protein Rv3480c (Rv3480c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase Rv3481c (Rv3481c) — family_assigned: GAP family protein Rv3482c (Rv3482c) — dark: DUF2510 domain-containing protein Rv3483c (Rv3483c) — family_assigned: LppP/LprE family lipoprotein cpsA (Rv3484) — family_assigned: LCP family protein Rv3486 (Rv3486) — family_assigned: DoxX family protein Rv3488 (Rv3488) — family_assigned: PadR family transcriptional regulator Rv3489 (Rv3489) — family_assigned: hypothetical protein otsA (Rv3490) — requalified: trehalose-6-phosphate synthase Rv3491 (Rv3491) — family_assigned: hypothetical protein Rv3492c (Rv3492c) — requalified: Mce associated protein Rv3493c (Rv3493c) — requalified: mammalian cell entry protein mce4F (Rv3494c) — family_assigned: virulence factor Mce family protein lprN (Rv3495c) — family_assigned: Mce family lipoprotein LprN mce4D (Rv3496c) — family_assigned: virulence factor Mce family protein mce4C (Rv3497c) — family_assigned: virulence factor Mce family protein mce4B (Rv3498c) — family_assigned: virulence factor Mce family protein yrbE4B (Rv3500c) — family_assigned: ABC transporter permease yrbE4A (Rv3501c) — family_assigned: ABC transporter permease 3 790 kb 3 816 kb 3 842 kb 3 869 kb 3 896 kb 3 922 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.