MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 263 045–423 045 bp (160 000 bp)
+ strand − strand Rv0219 (Rv0219) — dark: hypothetical protein lipC (Rv0220) — requalified: esterase LipC Rv0221 (Rv0221) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase echA1 (Rv0222) — family_assigned: crotonase/enoyl-CoA hydratase family protein Rv0223c (Rv0223c) — requalified: aldehyde dehydrogenase Rv0224c (Rv0224c) — requalified: class I SAM-dependent methyltransferase Rv0225 (Rv0225) — family_assigned: glycosyltransferase family 4 protein mmpA (Rv0226c) — requalified: hypothetical protein Rv0228 (Rv0228) — requalified: acyltransferase Rv0229c (Rv0229c) — family_assigned: PIN domain nuclease php (Rv0230c) — requalified: phosphotriesterase-related protein fadE4 (Rv0231) — family_assigned: acyl-CoA dehydrogenase family protein Rv0232 (Rv0232) — family_assigned: TetR/AcrR family transcriptional regulator nrdB (Rv0233) — requalified: R2-like ligand-binding oxidase Rv0235c (Rv0235c) — family_assigned: lipase maturation factor family protein aftD (Rv0236c) — family_assigned: DUF3367 domain-containing protein aftD Rv0238 (Rv0238) — family_assigned: TetR/AcrR family transcriptional regulator vapB24 (Rv0239) — requalified: antitoxin vapC24 (Rv0240) — family_assigned: type II toxin-antitoxin system VapC family toxin htdX (Rv0241c) — requalified: 3-hydroxyacyl-thioester dehydratase HtdX fabG4 (Rv0242c) — requalified: 3-oxoacyl-ACP reductase fadA2 (Rv0243) — requalified: acetyl-CoA C-acetyltransferase fadE5 (Rv0244c) — requalified: acyl-CoA dehydrogenase Rv0245 (Rv0245) — family_assigned: flavin reductase family protein Rv0246 (Rv0246) — family_assigned: integral membrane protein Rv0247c (Rv0247c) — family_assigned: succinate dehydrogenase/fumarate reductase iron-sulfur subun Rv0248c (Rv0248c) — family_assigned: fumarate reductase/succinate dehydrogenase flavoprotein subu Rv0249c (Rv0249c) — family_assigned: succinate dehydrogenase membrane anchor subunit Rv0250c (Rv0250c) — family_assigned: hypothetical protein hsp (Rv0251c) — requalified: stress-responsive chaperone Acr2 nirB (Rv0252) — family_assigned: nitrite reductase large subunit NirB nirD (Rv0253) — family_assigned: nitrite reductase small subunit NirD cobU (Rv0254c) — requalified: bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph Rv0258c (Rv0258c) — requalified: hypothetical protein Rv0259c (Rv0259c) — family_assigned: sirohydrochlorin chelatase Rv0260c (Rv0260c) — requalified: uroporphyrinogen-III synthase narK3 (Rv0261c) — requalified: nitrate/nitrite transporter Rv0263c (Rv0263c) — family_assigned: 5-oxoprolinase/urea amidolyase family protein Rv0264c (Rv0264c) — family_assigned: allophanate hydrolase subunit 1 oplA (Rv0266c) — family_assigned: hydantoinase B/oxoprolinase family protein narU (Rv0267) — family_assigned: NarK family nitrate/nitrite MFS transporter Rv0269c (Rv0269c) — requalified: DNA polymerase domain-containing protein fadD2 (Rv0270) — requalified: long-chain-fatty-acid--CoA ligase FadD2 fadE6 (Rv0271c) — family_assigned: acyl-CoA dehydrogenase family protein Rv0272c (Rv0272c) — family_assigned: alpha/beta hydrolase Rv0273c (Rv0273c) — family_assigned: TetR/AcrR family transcriptional regulator Rv0274 (Rv0274) — family_assigned: VOC family protein Rv0276 (Rv0276) — family_assigned: oxygenase MpaB family protein vapC25 (Rv0277c) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv0281 (Rv0281) — requalified: class I SAM-dependent methyltransferase eccB3 (Rv0283) — family_assigned: type VII secretion system ESX-3 subunit EccB3 eccC3 (Rv0284) — family_assigned: type VII secretion system ESX-3 FtsK/SpoIIIE family ATPase E esxG (Rv0287) — requalified: type VII secretion system protein EsxG esxH (Rv0288) — requalified: type VII secretion system effector EsxH espG3 (Rv0289) — requalified: type VII secretion system ESX-3 associated protein EspG3 eccD3 (Rv0290) — family_assigned: type VII secretion system ESX-3 subunit EccD3 mycP3 (Rv0291) — requalified: type VII secretion system ESX-3 serine protease mycosin MycP eccE3 (Rv0292) — family_assigned: type VII secretion system ESX-3 subunit EccE3 Rv0293c (Rv0293c) — requalified: alpha/beta fold hydrolase tam (Rv0294) — requalified: trans-aconitate 2-methyltransferase Rv0295c (Rv0295c) — family_assigned: Stf0 family sulfotransferase Rv0298 (Rv0298) — family_assigned: ribbon-helix-helix protein%2C CopG family Rv0299 (Rv0299) — requalified: toxin-antitoxin system toxin vapB2 (Rv0300) — requalified: type II toxin-antitoxin system antitoxin VapB2 vapC2 (Rv0301) — family_assigned: PIN domain nuclease Rv0302 (Rv0302) — family_assigned: TetR/AcrR family transcriptional regulator Rv0303 (Rv0303) — requalified: protochlorophyllide reductase bluB (Rv0306) — requalified: 5%2C6-dimethylbenzimidazole synthase Rv0307c (Rv0307c) — family_assigned: hypothetical protein Rv0308 (Rv0308) — family_assigned: phosphatase PAP2 family protein Rv0309 (Rv0309) — requalified: L%2CD-transpeptidase Rv0310c (Rv0310c) — family_assigned: nuclear transport factor 2 family protein Rv0311 (Rv0311) — family_assigned: hypothetical protein Rv0312 (Rv0312) — family_assigned: Hsp70 family protein Rv0313 (Rv0313) — family_assigned: hypothetical protein Rv0315 (Rv0315) — requalified: family 16 glycosylhydrolase Rv0316 (Rv0316) — family_assigned: muconolactone Delta-isomerase family protein glpQ2 (Rv0317c) — requalified: glycerophosphodiester phosphodiesterase pcp (Rv0319) — requalified: pyroglutamyl-peptidase I Rv0320 (Rv0320) — family_assigned: hypothetical protein dcd (Rv0321) — requalified: dCTP deaminase udgA (Rv0322) — family_assigned: UDP-glucose/GDP-mannose dehydrogenase family protein Rv0323c (Rv0323c) — family_assigned: PIG-L deacetylase family protein Rv0324 (Rv0324) — family_assigned: metalloregulator ArsR/SmtB family transcription factor cyp135A1 (Rv0327c) — requalified: cytochrome P450 Rv0328 (Rv0328) — family_assigned: TetR/AcrR family transcriptional regulator Rv0329c (Rv0329c) — requalified: class I SAM-dependent methyltransferase Rv0330c (Rv0330c) — family_assigned: helix-turn-helix domain-containing protein Rv0331 (Rv0331) — requalified: FAD/NAD(P)-binding oxidoreductase Rv0333 (Rv0333) — family_assigned: nuclear transport factor 2 family protein rmlA (Rv0334) — requalified: glucose-1-phosphate thymidylyltransferase RfbA aspC (Rv0337c) — requalified: pyridoxal phosphate-dependent aminotransferase Rv0338c (Rv0338c) — requalified: heterodisulfide reductase-related iron-sulfur binding cluste iniR (Rv0339c) — family_assigned: isoniazid response ATPase/transcriptional regulator IniR Rv0340 (Rv0340) — family_assigned: Rv0340 family IniB-related protein iniB (Rv0341) — requalified: isoniazid-induced protein IniB iniC (Rv0343) — requalified: isoniazid-induced dynamin-like GTPase IniC lpqJ (Rv0344c) — family_assigned: hypothetical protein mosR (Rv0348) — family_assigned: hypoxia/intracellular survival transcriptional regulator Mos 265 kb 292 kb 318 kb 344 kb 371 kb 398 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.