MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 620 161–2 820 161 bp (200 000 bp)
+ strand − strand Rv2324 (Rv2324) — family_assigned: Lrp/AsnC family transcriptional regulator Rv2325c (Rv2325c) — family_assigned: CbiQ family ECF transporter T component Rv2327 (Rv2327) — family_assigned: MarR family winged helix-turn-helix transcriptional regulato narK1 (Rv2329c) — requalified: nitrate/nitrite transporter lppP (Rv2330c) — family_assigned: LppP/LprE family lipoprotein Rv2331 (Rv2331) — family_assigned: hypothetical protein mez (Rv2332) — requalified: NAD-dependent malic enzyme stp (Rv2333c) — requalified: multidrug resistance protein Stp tyzA (Rv2336) — requalified: hypothetical protein tyzC (Rv2337c) — requalified: hypothetical protein moeW (Rv2338c) — family_assigned: ThiF family adenylyltransferase mmpL9 (Rv2339) — requalified: RND transporter MmpL9 cysE (Rv2335) — requalified: serine O-acetyltransferase lppQ (Rv2341) — dark: hypothetical protein Rv2342 (Rv2342) — family_assigned: hypothetical protein dnaG (Rv2343c) — requalified: DNA primase dgt (Rv2344c) — requalified: deoxyguanosinetriphosphate triphosphohydrolase Rv2345 (Rv2345) — family_assigned: TPM domain-containing protein esxO (Rv2346c) — requalified: type VII secretion system effector EsxO esxP (Rv2347c) — requalified: type VII secretion system ESX-5 protein EsxJ Rv2348c (Rv2348c) — family_assigned: hypothetical protein plcC (Rv2349c) — requalified: phospholipase C glyS (Rv2357c) — requalified: glycine--tRNA ligase smtB (Rv2358) — family_assigned: metalloregulator ArsR/SmtB family transcription factor zur (Rv2359) — requalified: zinc uptake transcriptional repressor Zur Rv2360c (Rv2360c) — family_assigned: hypothetical protein Rv2361c (Rv2361c) — requalified: decaprenyl diphosphate synthase recO (Rv2362c) — requalified: DNA repair protein RecO amiA2 (Rv2363) — requalified: amidase Rv2365c (Rv2365c) — requalified: cytidine deaminase Rv2366c (Rv2366c) — family_assigned: hemolysin family protein Rv2369c (Rv2369c) — dark: hypothetical protein Rv2370c (Rv2370c) — family_assigned: PucR family transcriptional regulator Rv2372c (Rv2372c) — requalified: 16S rRNA (uracil(1498)-N(3))-methyltransferase dnaJ2 (Rv2373c) — requalified: molecular chaperone DnaJ hrcA (Rv2374c) — requalified: heat-inducible transcriptional repressor HrcA Rv2375 (Rv2375) — family_assigned: type II toxin-antitoxin system VapB family antitoxin cfp2 (Rv2376c) — requalified: Low molecular weight antigen MTB12 mbtH (Rv2377c) — requalified: mycobactin NRPS accessory protein MbtH mbtG (Rv2378c) — requalified: NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtD (Rv2381c) — requalified: mycobactin polyketide synthase MbtD mbtC (Rv2382c) — requalified: polyketide synthetase MbtC mbtB (Rv2383c) — requalified: phenyloxazoline synthase MbtB mbtA (Rv2384) — requalified: bifunctional salicyl-AMP ligase/salicyl-S-ArCP synthetase Mb Rv2387 (Rv2387) — family_assigned: sodium-dependent bicarbonate transport family permease rpfD (Rv2389c) — requalified: resuscitation-promoting factor protein RpfD Rv2390c (Rv2390c) — family_assigned: hypothetical protein cysH (Rv2392) — requalified: phosphoadenylyl-sulfate reductase ggtB (Rv2394) — family_assigned: gamma-glutamyltransferase family protein Rv2395 (Rv2395) — family_assigned: oligopeptide transporter%2C OPT family cysW (Rv2398c) — family_assigned: sulfate ABC transporter permease subunit CysW cysT (Rv2399c) — family_assigned: sulfate ABC transporter permease subunit CysT subI (Rv2400c) — family_assigned: sulfate ABC transporter substrate-binding protein Rv2401 (Rv2401) — dark: hypothetical protein lppR (Rv2403c) — family_assigned: sensor domain-containing protein lepA (Rv2404c) — requalified: translation elongation factor 4 Rv2406c (Rv2406c) — family_assigned: CBS domain-containing protein Rv2407 (Rv2407) — family_assigned: Rv2407 family type 3 sulfatase Rv2409c (Rv2409c) — family_assigned: transglutaminase family protein Rv2410c (Rv2410c) — family_assigned: alpha-E domain-containing protein Rv2411c (Rv2411c) — requalified: circularly permuted type 2 ATP-grasp protein rpsT (Rv2412) — requalified: 30S ribosomal protein S20 Rv2413c (Rv2413c) — family_assigned: DNA polymerase III subunit delta Rv2414c (Rv2414c) — family_assigned: ComEC/Rec2 family competence protein Rv2415c (Rv2415c) — family_assigned: ComEA family DNA-binding protein Rv2417c (Rv2417c) — family_assigned: DegV family protein octT (Rv2418c) — requalified: diglucosylglycerate octanoyltransferase gpgP (Rv2419c) — requalified: glucosyl-3-phosphoglycerate phosphatase rsfS (Rv2420c) — requalified: ribosome silencing factor Rv2422 (Rv2422) — family_assigned: hypothetical protein Rv2423 (Rv2423) — requalified: class I SAM-dependent methyltransferase Rv2425c (Rv2425c) — family_assigned: VWA domain-containing protein Rv2426c (Rv2426c) — family_assigned: MoxR family ATPase proA (Rv2427c) — requalified: glutamate-5-semialdehyde dehydrogenase ahpC (Rv2428) — requalified: peroxiredoxin AhpC ahpD (Rv2429) — requalified: alkyl hydroperoxide reductase Rv2432c (Rv2432c) — dark: hypothetical protein nrtS (Rv2433c) — requalified: nitrate/nitrite transporter NrtS Rv2434c (Rv2434c) — requalified: mechanosensitive ion channel Rv2435c (Rv2435c) — family_assigned: adenylate/guanylate cyclase domain-containing protein rbsK (Rv2436) — requalified: ribokinase RbsK Rv2437 (Rv2437) — family_assigned: isoprenylcysteine carboxylmethyltransferase family protein nadE (Rv2438c) — requalified: NAD(+) synthase proB (Rv2439c) — requalified: glutamate 5-kinase obg (Rv2440c) — requalified: GTPase ObgE rpmA (Rv2441c) — requalified: 50S ribosomal protein L27 rplU (Rv2442c) — requalified: 50S ribosomal protein L21 dctA (Rv2443) — family_assigned: cation:dicarboxylase symporter family transporter rne (Rv2444c) — family_assigned: Rne/Rng family ribonuclease ndkA (Rv2445c) — requalified: nucleoside-diphosphate kinase Rv2446c (Rv2446c) — dark: DUF4233 domain-containing protein folC (Rv2447c) — requalified: bifunctional tetrahydrofolate synthase/dihydrofolate synthas Rv2449c (Rv2449c) — family_assigned: trans-acting enoyl reductase family protein rpfE (Rv2450c) — requalified: resuscitation-promoting factor protein RpfE Rv2451 (Rv2451) — dark: hypothetical protein Rv2452c (Rv2452c) — dark: hypothetical protein mobA (Rv2453c) — requalified: molybdenum cofactor guanylyltransferase Rv2454c (Rv2454c) — family_assigned: 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2455c (Rv2455c) — family_assigned: 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2456c (Rv2456c) — requalified: MFS transporter clpX (Rv2457c) — family_assigned: ATP-dependent Clp protease ATP-binding subunit ClpX mmuM (Rv2458) — requalified: homocysteine S-methyltransferase jefA (Rv2459) — requalified: multidrug efflux pump JefA clpP2 (Rv2460c) — family_assigned: ATP-dependent CLP protease proteolytic subunit ClpP2 tig (Rv2462c) — requalified: trigger factor lipP (Rv2463) — family_assigned: serine hydrolase domain-containing protein Rv2464c (Rv2464c) — family_assigned: Fpg/Nei family DNA glycosylase Rv2466c (Rv2466c) — family_assigned: Rv2466c family mycothiol-dependent reductase Rv2469c (Rv2469c) — requalified: HNH endonuclease glbO (Rv2470) — requalified: group 2 truncated hemoglobin GlbO aglA (Rv2471) — family_assigned: glycoside hydrolase family 13 protein Rv2472 (Rv2472) — dark: hypothetical protein Rv2473 (Rv2473) — dark: hypothetical protein Rv2474c (Rv2474c) — family_assigned: hypothetical protein Rv2475c (Rv2475c) — family_assigned: thioesterase family protein gdh (Rv2476c) — requalified: NAD-glutamate dehydrogenase ettA (Rv2477c) — requalified: energy-dependent translational throttle protein EttA Rv2481c (Rv2481c) — family_assigned: hypothetical protein plsB2 (Rv2482c) — requalified: glycerol-3-phosphate 1-O-acyltransferase plsC (Rv2483c) — family_assigned: HAD-IB family hydrolase Rv2484c (Rv2484c) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase lipQ (Rv2485c) — family_assigned: alpha/beta hydrolase echA14 (Rv2486) — requalified: enoyl-CoA hydratase 2 646 kb 2 680 kb 2 714 kb 2 747 kb 2 780 kb 2 814 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.