MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 055 125–1 215 125 bp (160 000 bp)
+ strand − strand Rv0941c (Rv0941c) — family_assigned: STAS domain-containing protein Rv0942 (Rv0942) — dark: hypothetical protein Rv0943c (Rv0943c) — dark: hypothetical protein pgi (Rv0946c) — requalified: glucose-6-phosphate isomerase Rv0948c (Rv0948c) — requalified: chorismate mutase Rv0950c (Rv0950c) — family_assigned: M23 family metallopeptidase sucC (Rv0951) — family_assigned: ADP-forming succinate--CoA ligase subunit beta Rv0953c (Rv0953c) — requalified: LLM class F420-dependent oxidoreductase Rv0954 (Rv0954) — requalified: DUF5336 domain-containing protein Rv0955 (Rv0955) — family_assigned: DUF6350 family protein purN (Rv0956) — requalified: phosphoribosylglycinamide formyltransferase purH (Rv0957) — requalified: bifunctional phosphoribosylaminoimidazolecarboxamide formylt Rv0958 (Rv0958) — family_assigned: ATP-binding protein Rv0959 (Rv0959) — family_assigned: VWA domain-containing protein vapC9 (Rv0960) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv0961 (Rv0961) — dark: hypothetical protein lprP (Rv0962c) — family_assigned: LppA family lipoprotein Rv0965c (Rv0965c) — family_assigned: hypothetical protein Rv0966c (Rv0966c) — dark: DUF1707 domain-containing protein csoR (Rv0967) — requalified: copper-sensing transcriptional repressor CsoR Rv0968 (Rv0968) — family_assigned: DUF1490 family protein ctpV (Rv0969) — requalified: copper-translocating P-type ATPase Rv0970 (Rv0970) — family_assigned: DUF5134 domain-containing protein echA7 (Rv0971c) — family_assigned: enoyl-CoA hydratase family protein fadE12 (Rv0972c) — requalified: acyl-CoA dehydrogenase accA2 (Rv0973c) — family_assigned: biotin carboxylase N-terminal domain-containing protein accD2 (Rv0974c) — family_assigned: acyl-CoA carboxylase subunit beta fadE13 (Rv0975c) — family_assigned: acyl-CoA dehydrogenase family protein Rv0976c (Rv0976c) — family_assigned: acyclic terpene utilization AtuA family protein Rv0979c (Rv0979c) — dark: hypothetical protein mprA (Rv0981) — requalified: two-component system response regulator MprA mprB (Rv0982) — requalified: two-component system sensor histidine kinase MprB pepD (Rv0983) — requalified: serine protease PepD moaB2 (Rv0984) — family_assigned: MogA/MoaB family molybdenum cofactor biosynthesis protein mscL (Rv0985c) — requalified: large-conductance mechanosensitive channel protein MscL Rv0986 (Rv0986) — family_assigned: ABC transporter ATP-binding protein Rv0987 (Rv0987) — family_assigned: FtsX-like permease family protein Rv0988 (Rv0988) — family_assigned: lipocalin-like domain-containing protein grcC2 (Rv0989c) — requalified: polyprenyl-diphosphate synthase GrcC Rv0990c (Rv0990c) — family_assigned: SAF domain-containing protein Rv0991c (Rv0991c) — family_assigned: FmdB family zinc ribbon protein Rv0992c (Rv0992c) — requalified: 5-formyltetrahydrofolate cyclo-ligase galU (Rv0993) — requalified: UTP--glucose-1-phosphate uridylyltransferase Rv0996 (Rv0996) — family_assigned: hypothetical protein Rv0998 (Rv0998) — family_assigned: GNAT family N-acetyltransferase arcA (Rv1001) — requalified: arginine deiminase Rv1002c (Rv1002c) — requalified: dolichyl-phosphate-mannose--protein mannosyltransferase rsmI (Rv1003) — requalified: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Rv1004c (Rv1004c) — family_assigned: hypothetical protein Rv1006 (Rv1006) — family_assigned: hypothetical protein metS (Rv1007c) — requalified: methionine--tRNA ligase ksgA (Rv1010) — requalified: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltra Rv1012 (Rv1012) — dark: hypothetical protein pks16 (Rv1013) — requalified: fatty acyl-AMP ligase pth (Rv1014c) — requalified: aminoacyl-tRNA hydrolase rplY (Rv1015c) — requalified: 50S ribosomal protein L25/general stress protein Ctc prsA (Rv1017c) — requalified: ribose-phosphate diphosphokinase glmU (Rv1018c) — requalified: bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosa Rv1019 (Rv1019) — family_assigned: TetR/AcrR family transcriptional regulator mfd (Rv1020) — requalified: transcription-repair coupling factor Rv1021 (Rv1021) — requalified: nucleoside triphosphate pyrophosphohydrolase lpqU (Rv1022) — requalified: lytic murein transglycosylase eno (Rv1023) — requalified: phosphopyruvate hydratase Rv1024 (Rv1024) — family_assigned: septum formation initiator family protein ppx2 (Rv1026) — requalified: exopolyphosphatase Ppx2 kdpE (Rv1027c) — requalified: two-component system response regulator KdpE kdpD (Rv1028c) — requalified: sensor histidine kinase KdpD kdpA (Rv1029) — family_assigned: potassium-transporting ATPase subunit KdpA kdpB (Rv1030) — family_assigned: potassium-transporting ATPase subunit KdpB kdpC (Rv1031) — family_assigned: K(+)-transporting ATPase subunit C trcS (Rv1032c) — family_assigned: HAMP domain-containing sensor histidine kinase trcR (Rv1033c) — requalified: two-component system response regulator TrcR Rv1043c (Rv1043c) — requalified: serine protease Rv1044 (Rv1044) — family_assigned: type IV toxin-antitoxin system AbiEi family antitoxin domain Rv1045 (Rv1045) — family_assigned: nucleotidyl transferase AbiEii/AbiGii toxin family protein Rv1048c (Rv1048c) — dark: hypothetical protein Rv1049 (Rv1049) — requalified: oxidation-sensing regulator MosR Rv1050 (Rv1050) — family_assigned: SDR family oxidoreductase Rv1056 (Rv1056) — family_assigned: DUF427 domain-containing protein Rv1057 (Rv1057) — family_assigned: YncE family protein fadD14 (Rv1058) — requalified: long-chain fatty acid--CoA ligase Rv1059 (Rv1059) — requalified: dihydrodipicolinate reductase Rv1060 (Rv1060) — family_assigned: SRPBCC family protein Rv1061 (Rv1061) — requalified: class II glutamine amidotransferase Rv1062 (Rv1062) — family_assigned: patatin-like phospholipase family protein Rv1063c (Rv1063c) — family_assigned: patatin family protein lpqV (Rv1064c) — requalified: lipoprotein LpqV Rv1065 (Rv1065) — family_assigned: cysteine dioxygenase family protein Rv1066 (Rv1066) — family_assigned: rhodanese-like domain-containing protein Rv1069c (Rv1069c) — family_assigned: alpha/beta-hydrolase family protein echA8 (Rv1070c) — requalified: enoyl-CoA hydratase echA9 (Rv1071c) — family_assigned: enoyl-CoA hydratase/isomerase family protein Rv1072 (Rv1072) — family_assigned: Bax inhibitor-1/YccA family protein Rv1073 (Rv1073) — family_assigned: hypothetical protein fadA3 (Rv1074c) — requalified: acetyl-CoA C-acetyltransferase Rv1075c (Rv1075c) — family_assigned: SGNH/GDSL hydrolase family protein pra (Rv1078) — family_assigned: RDD family protein metB (Rv1079) — requalified: cystathionine gamma-synthase Rv1081c (Rv1081c) — dark: DUF4307 domain-containing protein mca (Rv1082) — requalified: mycothiol conjugate amidase Mca 1 060 kb 1 086 kb 1 113 kb 1 140 kb 1 166 kb 1 192 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.