MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 2 513 413–2 673 413 bp (160 000 bp)
+ strand − strand glnA1 (Rv2220) — requalified: type I glutamate--ammonia ligase glnE (Rv2221c) — requalified: bifunctional [glutamine synthetase] adenylyltransferase/[glu glnA2 (Rv2222c) — family_assigned: glutamine synthetase family protein caeB (Rv2223c) — requalified: carboxylesterase CaeB caeA (Rv2224c) — requalified: carboxylesterase CaeA panB (Rv2225) — requalified: 3-methyl-2-oxobutanoate hydroxymethyltransferase Rv2226 (Rv2226) — family_assigned: CYTH and CHAD domain-containing protein Rv2229c (Rv2229c) — family_assigned: zinc ribbon domain-containing protein Rv2230c (Rv2230c) — requalified: Nif3-like dinuclear metal center hexameric protein ptpA (Rv2234) — requalified: protein-tyrosine-phosphatase Rv2235 (Rv2235) — family_assigned: SURF1 family protein cobD (Rv2236c) — requalified: cobalamin biosynthesis protein ahpE (Rv2238c) — requalified: peroxiredoxin AhpE Rv2240c (Rv2240c) — family_assigned: hypothetical protein Rv2242 (Rv2242) — family_assigned: PucR family transcriptional regulator fabD (Rv2243) — requalified: malonyl CoA-acyl carrier protein transacylase acpM (Rv2244) — requalified: meromycolate extension acyl carrier protein AcpM kasA (Rv2245) — requalified: 3-oxoacyl-ACP synthase KasA accD6 (Rv2247) — family_assigned: acyl-CoA carboxylase subunit beta glpD1 (Rv2249c) — requalified: glycerol-3-phosphate dehydrogenase/oxidase Rv2250c (Rv2250c) — family_assigned: TetR/AcrR family transcriptional regulator Rv2252 (Rv2252) — requalified: diacylglycerol kinase Rv2253 (Rv2253) — family_assigned: hypothetical protein Rv2254c (Rv2254c) — family_assigned: LysE family transporter Rv2257c (Rv2257c) — family_assigned: serine hydrolase domain-containing protein Rv2258c (Rv2258c) — requalified: class I SAM-dependent methyltransferase mscR (Rv2259) — requalified: S-(hydroxymethyl)mycothiol dehydrogenase Rv2260 (Rv2260) — requalified: MBL fold metallo-hydrolase Rv2263 (Rv2263) — family_assigned: SDR family oxidoreductase Rv2264c (Rv2264c) — family_assigned: Hsp70 family protein Rv2265 (Rv2265) — requalified: MFS transporter cyp124 (Rv2266) — requalified: methyl-branched lipid omega-hydroxylase Cyp124 Rv2267c (Rv2267c) — requalified: sulfotransferase cyp128 (Rv2268c) — requalified: cytochrome P450 Rv2269c (Rv2269c) — family_assigned: hypothetical protein lppN (Rv2270) — family_assigned: hypothetical protein Rv2271 (Rv2271) — dark: DUF2695 domain-containing protein Rv2272 (Rv2272) — family_assigned: YidH family protein Rv2273 (Rv2273) — dark: DUF202 domain-containing protein mazF8 (Rv2274c) — requalified: toxin cyp121 (Rv2276) — requalified: mycocyclosin synthase Cyp121 pitB (Rv2281) — requalified: anion permease Rv2282c (Rv2282c) — family_assigned: LysR family transcriptional regulator Rv2283 (Rv2283) — dark: hypothetical protein lipM (Rv2284) — family_assigned: alpha/beta hydrolase Rv2285 (Rv2285) — family_assigned: wax ester/triacylglycerol synthase family O-acyltransferase Rv2286c (Rv2286c) — family_assigned: DsbA family protein Rv2288 (Rv2288) — dark: hypothetical protein cdh (Rv2289) — requalified: CDP-diacylglycerol diphosphatase lppO (Rv2290) — requalified: lipoprotein LpqH sseB (Rv2291) — requalified: sulfurtransferase Rv2294 (Rv2294) — family_assigned: MalY/PatB family protein Rv2295 (Rv2295) — family_assigned: CbrC family protein Rv2296 (Rv2296) — requalified: haloalkane dehalogenase Rv2297 (Rv2297) — dark: hypothetical protein Rv2298 (Rv2298) — requalified: aldo/keto reductase htpG (Rv2299c) — requalified: molecular chaperone HtpG cut2 (Rv2301) — family_assigned: cutinase family protein Rv2302 (Rv2302) — family_assigned: DUF1918 domain-containing protein Rv2303c (Rv2303c) — family_assigned: amidohydrolase family protein Rv2304c (Rv2304c) — dark: hypothetical protein Rv2305 (Rv2305) — family_assigned: hypothetical protein Rv2307c (Rv2307c) — family_assigned: alpha/beta hydrolase Rv2308 (Rv2308) — family_assigned: DUF433 domain-containing protein Rv2312 (Rv2312) — dark: hypothetical protein Rv2313c (Rv2313c) — family_assigned: carboxymuconolactone decarboxylase family protein Rv2314c (Rv2314c) — family_assigned: TldD/PmbA family protein Rv2315c (Rv2315c) — family_assigned: TldD/PmbA family protein uspA (Rv2316) — family_assigned: sugar ABC transporter permease uspC (Rv2318) — family_assigned: sugar ABC transporter substrate-binding protein Rv2319c (Rv2319c) — requalified: universal stress protein rocE (Rv2320c) — requalified: amino acid permease Rv2324 (Rv2324) — family_assigned: Lrp/AsnC family transcriptional regulator Rv2325c (Rv2325c) — family_assigned: CbiQ family ECF transporter T component Rv2327 (Rv2327) — family_assigned: MarR family winged helix-turn-helix transcriptional regulato narK1 (Rv2329c) — requalified: nitrate/nitrite transporter lppP (Rv2330c) — family_assigned: LppP/LprE family lipoprotein Rv2331 (Rv2331) — family_assigned: hypothetical protein mez (Rv2332) — requalified: NAD-dependent malic enzyme stp (Rv2333c) — requalified: multidrug resistance protein Stp tyzA (Rv2336) — requalified: hypothetical protein tyzC (Rv2337c) — requalified: hypothetical protein moeW (Rv2338c) — family_assigned: ThiF family adenylyltransferase mmpL9 (Rv2339) — requalified: RND transporter MmpL9 cysE (Rv2335) — requalified: serine O-acetyltransferase lppQ (Rv2341) — dark: hypothetical protein Rv2342 (Rv2342) — family_assigned: hypothetical protein dnaG (Rv2343c) — requalified: DNA primase dgt (Rv2344c) — requalified: deoxyguanosinetriphosphate triphosphohydrolase Rv2345 (Rv2345) — family_assigned: TPM domain-containing protein esxO (Rv2346c) — requalified: type VII secretion system effector EsxO esxP (Rv2347c) — requalified: type VII secretion system ESX-5 protein EsxJ Rv2348c (Rv2348c) — family_assigned: hypothetical protein plcC (Rv2349c) — requalified: phospholipase C glyS (Rv2357c) — requalified: glycine--tRNA ligase smtB (Rv2358) — family_assigned: metalloregulator ArsR/SmtB family transcription factor zur (Rv2359) — requalified: zinc uptake transcriptional repressor Zur Rv2360c (Rv2360c) — family_assigned: hypothetical protein Rv2361c (Rv2361c) — requalified: decaprenyl diphosphate synthase recO (Rv2362c) — requalified: DNA repair protein RecO amiA2 (Rv2363) — requalified: amidase Rv2365c (Rv2365c) — requalified: cytidine deaminase Rv2366c (Rv2366c) — family_assigned: hemolysin family protein 2 518 kb 2 544 kb 2 570 kb 2 597 kb 2 624 kb 2 650 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.