MTBC Gene Atlas

Genome browser

Linear view of the M. tuberculosis complex genome (MTBC0 ancestral coordinates, H37Rv locus tags). Each arrow is a gene, pointing in its coding direction and coloured by annotation verdict. Click a gene to open its page.

◀ Pan left Pan right ▶ + Zoom in − Zoom out window 1 152 087–1 312 087 bp (160 000 bp)
+ strand − strand eno (Rv1023) — requalified: phosphopyruvate hydratase Rv1024 (Rv1024) — family_assigned: septum formation initiator family protein ppx2 (Rv1026) — requalified: exopolyphosphatase Ppx2 kdpE (Rv1027c) — requalified: two-component system response regulator KdpE kdpD (Rv1028c) — requalified: sensor histidine kinase KdpD kdpA (Rv1029) — family_assigned: potassium-transporting ATPase subunit KdpA kdpB (Rv1030) — family_assigned: potassium-transporting ATPase subunit KdpB kdpC (Rv1031) — family_assigned: K(+)-transporting ATPase subunit C trcS (Rv1032c) — family_assigned: HAMP domain-containing sensor histidine kinase trcR (Rv1033c) — requalified: two-component system response regulator TrcR Rv1043c (Rv1043c) — requalified: serine protease Rv1044 (Rv1044) — family_assigned: type IV toxin-antitoxin system AbiEi family antitoxin domain Rv1045 (Rv1045) — family_assigned: nucleotidyl transferase AbiEii/AbiGii toxin family protein Rv1048c (Rv1048c) — dark: hypothetical protein Rv1049 (Rv1049) — requalified: oxidation-sensing regulator MosR Rv1050 (Rv1050) — family_assigned: SDR family oxidoreductase Rv1056 (Rv1056) — family_assigned: DUF427 domain-containing protein Rv1057 (Rv1057) — family_assigned: YncE family protein fadD14 (Rv1058) — requalified: long-chain fatty acid--CoA ligase Rv1059 (Rv1059) — requalified: dihydrodipicolinate reductase Rv1060 (Rv1060) — family_assigned: SRPBCC family protein Rv1061 (Rv1061) — requalified: class II glutamine amidotransferase Rv1062 (Rv1062) — family_assigned: patatin-like phospholipase family protein Rv1063c (Rv1063c) — family_assigned: patatin family protein lpqV (Rv1064c) — requalified: lipoprotein LpqV Rv1065 (Rv1065) — family_assigned: cysteine dioxygenase family protein Rv1066 (Rv1066) — family_assigned: rhodanese-like domain-containing protein Rv1069c (Rv1069c) — family_assigned: alpha/beta-hydrolase family protein echA8 (Rv1070c) — requalified: enoyl-CoA hydratase echA9 (Rv1071c) — family_assigned: enoyl-CoA hydratase/isomerase family protein Rv1072 (Rv1072) — family_assigned: Bax inhibitor-1/YccA family protein Rv1073 (Rv1073) — family_assigned: hypothetical protein fadA3 (Rv1074c) — requalified: acetyl-CoA C-acetyltransferase Rv1075c (Rv1075c) — family_assigned: SGNH/GDSL hydrolase family protein pra (Rv1078) — family_assigned: RDD family protein metB (Rv1079) — requalified: cystathionine gamma-synthase Rv1081c (Rv1081c) — dark: DUF4307 domain-containing protein mca (Rv1082) — requalified: mycothiol conjugate amidase Mca Rv1083 (Rv1083) — dark: hypothetical protein Rv1084 (Rv1084) — family_assigned: thioredoxin domain-containing protein Rv1085c (Rv1085c) — family_assigned: hemolysin III family protein Rv1086 (Rv1086) — family_assigned: undecaprenyl diphosphate synthase family protein desA2 (Rv1094) — requalified: acyl-ACP desaturase phoH2 (Rv1095) — family_assigned: PhoH family protein Rv1096 (Rv1096) — family_assigned: polysaccharide deacetylase family protein Rv1097c (Rv1097c) — family_assigned: hypothetical protein fum (Rv1098c) — requalified: class II fumarate hydratase glpX (Rv1099c) — requalified: class II fructose-bisphosphatase Rv1101c (Rv1101c) — family_assigned: AI-2E family transporter mazF3 (Rv1102c) — requalified: type II toxin-antitoxin system toxin endoribonuclease MazF3 Rv1106c (Rv1106c) — requalified: 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase xseB (Rv1107c) — family_assigned: exodeoxyribonuclease VII small subunit xseA (Rv1108c) — family_assigned: exodeoxyribonuclease VII large subunit Rv1109c (Rv1109c) — requalified: lipid droplet-associated protein Rv1111c (Rv1111c) — family_assigned: DUF6542 domain-containing protein ychF (Rv1112) — requalified: redox-regulated ATPase YchF vapB32 (Rv1113) — family_assigned: type II toxin-antitoxin system VapB family antitoxin vapC32 (Rv1114) — family_assigned: type II toxin-antitoxin system VapC family toxin Rv1115 (Rv1115) — family_assigned: hypothetical protein Rv1116 (Rv1116) — dark: hypothetical protein Rv1117 (Rv1117) — family_assigned: putative quinol monooxygenase gnd2 (Rv1122) — requalified: decarboxylating 6-phosphogluconate dehydrogenase Rv1125 (Rv1125) — family_assigned: WS/DGAT domain-containing protein Rv1126c (Rv1126c) — family_assigned: MarR family transcriptional regulator ppdK (Rv1127c) — requalified: pyruvate%2C phosphate dikinase Rv1129c (Rv1129c) — family_assigned: short-chain fatty acyl-CoA regulator family protein prpC (Rv1131) — requalified: 2-methylcitrate synthase Rv1132 (Rv1132) — family_assigned: DUF3556 domain-containing protein metE (Rv1133c) — requalified: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl Rv1134 (Rv1134) — family_assigned: hypothetical protein Rv1138c (Rv1138c) — requalified: NAD(P)/FAD-dependent oxidoreductase Rv1139c (Rv1139c) — family_assigned: isoprenylcysteine carboxyl methyltransferase family protein echA11 (Rv1141c) — requalified: enoyl-CoA hydratase echA10 (Rv1142c) — requalified: enoyl-CoA hydratase mcr (Rv1143) — requalified: alpha-methylacyl-CoA racemase Rv1144 (Rv1144) — requalified: 3-hydroxyacyl-CoA dehydrogenase Rv1147 (Rv1147) — family_assigned: methyltransferase domain-containing protein cobB (Rv1151c) — requalified: NAD-dependent protein deacylase Rv1152 (Rv1152) — family_assigned: GntR family transcriptional regulator omt (Rv1153c) — requalified: class I SAM-dependent methyltransferase Rv1155 (Rv1155) — requalified: PPOX class F420-dependent oxidoreductase Rv1156 (Rv1156) — requalified: HhH-GPD-type base excision DNA repair protein Rv1157c (Rv1157c) — dark: hypothetical protein Rv1158c (Rv1158c) — dark: hypothetical protein pimE (Rv1159) — requalified: mannosyltransferase mutT2 (Rv1160) — requalified: 8-oxo-dGTP diphosphatase MutT narG (Rv1161) — family_assigned: nitrate reductase subunit alpha narI (Rv1164) — family_assigned: respiratory nitrate reductase subunit gamma typA (Rv1165) — requalified: translational GTPase TypA lpqW (Rv1166) — requalified: lipoarabinomannan biosynthesis protein LpqW Rv1167c (Rv1167c) — family_assigned: TetR/AcrR family transcriptional regulator mshB (Rv1170) — requalified: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyran Rv1171 (Rv1171) — family_assigned: hypothetical protein fbiC (Rv1173) — requalified: bifunctional FO biosynthesis protein CofGH 1 166 kb 1 192 kb 1 219 kb 1 246 kb 1 272 kb 1 298 kb

■ resolved (requalified)   ■ family assigned   ■ still unknown (dark)  ·  the centred gene is outlined in black.