Genes
1051 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2707 Rv2707 |
mtbc0_002881 |
hypothetical protein | YihY/virulence factor BrkB family protein. Pfam: Virul_fac_BrkB (PF03631.21). | Virul_fac_BrkB |
Family assigned |
| Rv2708c Rv2708c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF3039. Function unknown. Foldseek best (non-significant) hit: 1v6t-assembly1_A Crystal Structure of Lactam Utilization Protein from (prob 0.07, TM 0.34). | DUF3039 |
Still unknown |
| Rv2712c Rv2712c |
mtbc0_002886 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF4192. Function unknown. Foldseek best (non-significant) hit: 7ya9-assembly1_A-2 Fis1 (Mitochondrial fission 1 protein) (prob 0.99, TM 0.57). | DUF4192 |
Still unknown |
| Rv2714 Rv2714 |
mtbc0_002888 |
hypothetical protein | PAC2 family protein. Pfam: PAC2 (PF09754.16). | PAC2 |
Family assigned |
| Rv2716 Rv2716 |
mtbc0_002890 |
hypothetical protein | PhzF family phenazine biosynthesis protein. Pfam: PhzC-PhzF (PF02567.22). | PhzC-PhzF |
Family assigned |
| Rv2717c Rv2717c |
mtbc0_002891 |
hypothetical protein | FABP family protein. Pfam: THAP4_heme-bd (PF08768.18). | THAP4_heme-bd |
Family assigned |
| Rv2721c Rv2721c |
mtbc0_002895 |
hypothetical protein | LGFP repeat-containing protein. Pfam: LGFP (PF08310.18), ArfC (PF27542.1). | LGFP ArfC |
Family assigned |
| Rv2722 Rv2722 |
mtbc0_002896 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2728c Rv2728c |
mtbc0_002902 |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 5hee-assembly1_B Crystal structure of the TK2203 protein (prob 1.00, TM 0.73). Structure-based, putative. | Family assigned | |
| Rv2730 Rv2730 |
mtbc0_002904 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 5ejw-assembly1_A Crystal structure of chromobox homolog 7 (CBX7) chrom (prob 0.01, TM 0.29). | Still unknown | |
| Rv2731 Rv2731 |
mtbc0_002905 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF349. Function unknown. | DUF349 |
Still unknown |
| Rv2734 Rv2734 |
mtbc0_002908 |
hypothetical protein | DUF5131 family protein. | DUF5131 |
Family assigned |
| Rv2735c Rv2735c |
mtbc0_002909 |
hypothetical protein | Three-Cys-motif partner protein TcmP. | Resolved | |
| Rv2738c Rv2738c |
mtbc0_002913 |
hypothetical protein | Psp-like envelope-stress system protein (paralogue of the Rv2742c Psp module). RefSeq leaves it 'hypothetical protein'. | DUF3046 |
Family assigned |
| Rv2742c Rv2742c |
- |
hypothetical protein | Component of the mycobacterial Psp-like (phage-shock-protein) envelope-stress system. RefSeq leaves it 'hypothetical'. Rv2742c belongs to a four-gene module (clgR-pspA[Rv2744c]-rv2743c-rv2742c) regulated by ClgR and required for envelope integrity, surface-stress tolerance, MprAB-sigmaE stress signalling and intramacrophage growth; the module is restricted to tuberculous mycobacteria (Datta 2015). | DUF3046 |
Resolved |
| Rv2743c Rv2743c |
mtbc0_002920 |
hypothetical protein | Contains Rv2743c (PF25587.2) domain(s); putative function inferred from the domain architecture. | Rv2743c |
Family assigned |
| 35kd_ag Rv2744c |
- |
hypothetical protein | Contains PspA_IM30 (PF04012.18) domain(s); putative function inferred from the domain architecture. | PspA_IM30 |
Family assigned |
| Rv2749 Rv2749 |
mtbc0_002926 |
hypothetical protein | Putative quinol monooxygenase. Pfam: ABM (PF03992.23). | ABM |
Family assigned |
| Rv2751 Rv2751 |
mtbc0_002928 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| Rv2762c Rv2762c |
mtbc0_002939 |
hypothetical protein | Winged helix-turn-helix domain-containing protein. | Family assigned | |
| Rv2771c Rv2771c |
mtbc0_002950 |
hypothetical protein | Flavodoxin family protein. | Family assigned | |
| Rv2774c Rv2774c |
mtbc0_002953 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8rrr-assembly1_E Alpha-synuclein amyloid fibril (prob 0.00, TM 0.13). | Still unknown | |
| Rv2777c Rv2777c |
mtbc0_002956 |
hypothetical protein | Metal-dependent hydrolase. Pfam: Metal_hydrol (PF10118.15). | Metal_hydrol |
Resolved |
| Rv2778c Rv2778c |
mtbc0_002957 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv2787 Rv2787 |
mtbc0_002966 |
hypothetical protein | AAA family ATPase. Pfam: T7SS_EccA1_N (PF21545.4), CbiA (PF01656.30). | T7SS_EccA1_N CbiA |
Family assigned |
| Rv2795c Rv2795c |
mtbc0_002974 |
hypothetical protein | Metallophosphoesterase. Pfam: Metallophos (PF00149.34). | Metallophos |
Resolved |
| Rv2797c Rv2797c |
mtbc0_002976 |
hypothetical protein | Alpha/beta hydrolase family protein. Pfam: Abhydrolase_8 (PF06259.19). | Abhydrolase_8 |
Family assigned |
| Rv2798c Rv2798c |
mtbc0_002977 |
hypothetical protein | ESAT-6-like (WXG100) / ESX-secretion family protein (EsxF-like, four-helical bundle). RefSeq leaves it 'hypothetical protein'. | Family assigned | |
| Rv2803 Rv2803 |
- |
hypothetical protein | Contains TacA1 (PF08681.19) domain(s); putative function inferred from the domain architecture. | TacA1 |
Family assigned |
| Rv2804c Rv2804c |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2805 Rv2805 |
mtbc0_002985 |
hypothetical protein | Transposase. | Resolved | |
| Rv2807 Rv2807 |
- |
hypothetical protein | Contains rve (PF00665.33) domain(s); putative function inferred from the domain architecture. | rve |
Family assigned |
| Rv2808 Rv2808 |
mtbc0_002988 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6fnd-assembly1_B Crystal structure of Toxoplasma gondii AKMT (prob 0.16, TM 0.54). | Still unknown | |
| Rv2809 Rv2809 |
mtbc0_002989 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3rrr-assembly1_B Structure of the RSV F protein in the post-fusion con (prob 0.04, TM 0.47). | Still unknown | |
| Rv2811 Rv2811 |
mtbc0_002991 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 7av6-assembly1_A-2 FAST in a domain-swapped dimer form (prob 0.15, TM 0.36). | Still unknown | |
| Rv2813 Rv2813 |
mtbc0_002993 |
hypothetical protein | ExeA family protein. Pfam: AAA_22 (PF13401.13). | AAA_22 |
Family assigned |
| Rv2825c Rv2825c |
- |
hypothetical protein | Conserved hypothetical; function unknown. Structure-based hint rejected: structural ASCH hit contradicts the DUF1802 Pfam assignment; function unknown. | DUF1802 |
Still unknown |
| Rv2826c Rv2826c |
mtbc0_003004 |
hypothetical protein | Nucleotidyl transferase AbiEii/AbiGii toxin family protein. Pfam: AbiEii (PF08843.18). | AbiEii |
Family assigned |
| Rv2827c Rv2827c |
mtbc0_003005 |
hypothetical protein | Type IV toxin-antitoxin system AbiEi family antitoxin. Pfam: AbiEi_1 (PF09407.17). | AbiEi_1 |
Family assigned |
| Rv2828A Rv2828A |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2277. Function unknown. Foldseek best (non-significant) hit: 5wi4-assembly1_C CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH A (prob 0.20, TM 0.63). | DUF2277 |
Still unknown |
| Rv2828c Rv2828c |
mtbc0_003003 |
hypothetical protein | DUF1802 family protein. | DUF1802 |
Family assigned |
| Rv2840c Rv2840c |
- |
hypothetical protein | Contains YlxR (PF04296.19) domain(s); putative function inferred from the domain architecture. | YlxR |
Family assigned |
| Rv2843 Rv2843 |
mtbc0_003022 |
hypothetical protein | Small transmembrane protein, candidate subunit of the mycobacterial respiratory supercomplex (weak HHpred) RefSeq leaves this locus uncharacterised. | Family assigned | |
| Rv2844 Rv2844 |
mtbc0_003023 |
hypothetical protein | Ferritin-like domain-containing protein. | DUF4439 |
Family assigned |
| Rv2854 Rv2854 |
mtbc0_003033 |
hypothetical protein | Alpha/beta hydrolase. Pfam: Hydrolase_4 (PF12146.16), Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14). | Hydrolase_4 Abhydrolase_1 Abhydrolase_6 |
Family assigned |
| Rv2862c Rv2862c |
mtbc0_003043 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF1707. Function unknown. Foldseek best (non-significant) hit: 7yh8-assembly2_C Crystal structure of a heterochiral protein complex (prob 0.69, TM 0.74). | DUF1707 |
Still unknown |
| Rv2891 Rv2891 |
- |
hypothetical protein | Contains Peptidase_M23 (PF01551.30) domain(s); putative function inferred from the domain architecture. | Peptidase_M23 |
Family assigned |
| dprA Rv2896c |
mtbc0_003078 |
hypothetical protein | DNA-processing protein DprA. Pfam: DNA_processg_A (PF02481.22), WHD_DprA (PF17782.8). | DNA_processg_A WHD_DprA |
Resolved |
| Rv2897c Rv2897c |
mtbc0_003079 |
hypothetical protein | YifB family Mg chelatase-like AAA ATPase. Pfam: Lon_C (PF05362.20), ChlI (PF13541.13), Mg_chelatase (PF01078.28), Mg_chelatase_C (PF13335.13). | Lon_C ChlI Mg_chelatase Mg_chelatase_C |
Family assigned |
| Rv2898c Rv2898c |
mtbc0_003080 |
hypothetical protein | YraN family protein. | UPF0102 |
Family assigned |