Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| hisH Rv1602 |
mtbc0_001708 |
imidazole glycerol phosphate synthase subunit HisH | Imidazole glycerol phosphate synthase subunit HisH. Pfam: GATase (PF00117.35). | GATase |
Family assigned |
| hisA Rv1603 |
mtbc0_001709 |
1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase | Bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase/phosphoribosylanthranilate isomerase PriA. Pfam: His_biosynth (PF00977.28). | His_biosynth |
Resolved |
| impA Rv1604 |
mtbc0_001710 |
inositol-monophosphatase ImpA | Inositol monophosphatase family protein. Pfam: Inositol_P (PF00459.31). | Inositol_P |
Family assigned |
| hisF Rv1605 |
mtbc0_001711 |
imidazole glycerol phosphate synthase subunit HisF | Imidazole glycerol phosphate synthase subunit HisF. Pfam: His_biosynth (PF00977.28). | His_biosynth |
Family assigned |
| hisI Rv1606 |
mtbc0_001712 |
phosphoribosyl-AMP cyclohydrolase | Phosphoribosyl-AMP cyclohydrolase. Pfam: PRA-CH (PF01502.24). | PRA-CH |
Resolved |
| chaA Rv1607 |
mtbc0_001713 |
ionic transporter integral membrane protein ChaA | Calcium:proton antiporter. Pfam: Na_Ca_ex (PF01699.30). | Na_Ca_ex |
Resolved |
| bcpB Rv1608c |
mtbc0_001714 |
peroxiredoxin | Peroxiredoxin BcpB. Pfam: Redoxin (PF08534.17), AhpC-TSA (PF00578.28). | Redoxin AhpC-TSA |
Resolved |
| trpE Rv1609 |
mtbc0_001715 |
anthranilate synthase component I | Anthranilate synthase component I. Pfam: Anth_synt_I_N (PF04715.20), Chorismate_bind (PF00425.25). | Anth_synt_I_N Chorismate_bind |
Resolved |
| Rv1610 Rv1610 |
mtbc0_001716 |
membrane protein | TIGR02234 family membrane protein. Pfam: Trp_oprn_chp (PF09534.16). | Trp_oprn_chp |
Family assigned |
| trpC Rv1611 |
mtbc0_001717 |
indole-3-glycerol phosphate synthase | Indole-3-glycerol phosphate synthase TrpC. Pfam: IGPS (PF00218.28). | IGPS |
Resolved |
| trpB Rv1612 |
- |
tryptophan synthase subunit beta | Tryptophan synthase subunit beta. Pfam: PALP (PF00291.32). | PALP |
Family assigned |
| trpA Rv1613 |
mtbc0_001719 |
tryptophan synthase subunit alpha | Tryptophan synthase subunit alpha. Pfam: Trp_syntA (PF00290.27). | Trp_syntA |
Family assigned |
| lgt Rv1614 |
mtbc0_001720 |
prolipoprotein diacylglyceryl transferase | Prolipoprotein diacylglyceryl transferase. Pfam: LGT (PF01790.24). | LGT |
Resolved |
| Rv1615 Rv1615 |
mtbc0_001722 |
membrane protein | TM2 domain-containing protein. Pfam: TM2 (PF05154.22). | TM2 |
Family assigned |
| Rv1616 Rv1616 |
mtbc0_001723 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | DUF2752 |
Family assigned |
| pykA Rv1617 |
mtbc0_001724 |
pyruvate kinase | Pyruvate kinase. Pfam: PK (PF00224.28), PK_C (PF02887.22). | PK PK_C |
Resolved |
| tesB1 Rv1618 |
mtbc0_001725 |
acyl-CoA thioesterase II | Acyl-CoA thioesterase II. Pfam: 4HBT_3 (PF13622.13), Acyl_CoA_thio (PF02551.22), 4HBT_3C (PF20789.4). | 4HBT_3 Acyl_CoA_thio 4HBT_3C |
Resolved |
| Rv1619 Rv1619 |
mtbc0_001726 |
hypothetical protein | Bifunctional lysylphosphatidylglycerol flippase/synthetase MprF. Pfam: LPG_synthase_C (PF09924.16). | LPG_synthase_C |
Resolved |
| cydC Rv1620c |
mtbc0_001727 |
cytochrome biosyntheisis ABC transporter ATP-binding protein/permease CydC | Thiol reductant ABC exporter subunit CydC. Pfam: ABC_tran (PF00005.34). | ABC_tran |
Family assigned |
| cydD Rv1621c |
- |
cytochrome biosyntheisis ABC transporter ATP-binding protein/permease CydD | Cytochrome biosyntheisis ABC transporter ATP-binding protein/permease CydD. Pfam: ABC_membrane (PF00664.29), ABC_tran (PF00005.34). | ABC_membrane ABC_tran |
Family assigned |
| cydB Rv1622c |
mtbc0_001729 |
cytochrome D ubiquinol oxidase subunit II CydB | Cytochrome d ubiquinol oxidase subunit II. Pfam: Cyt_bd_oxida_II (PF02322.21). | Cyt_bd_oxida_II |
Family assigned |
| cydA Rv1623c |
- |
cytochrome D ubiquinol oxidase subunit I CydA | Cytochrome D ubiquinol oxidase subunit I CydA. Pfam: Cyt_bd_oxida_I (PF01654.23). | Cyt_bd_oxida_I |
Family assigned |
| Rv1624c Rv1624c |
mtbc0_001731 |
membrane protein | HdeD family acid-resistance protein. | DUF308 |
Family assigned |
| cya Rv1625c |
mtbc0_001732 |
adenylate cyclase | Adenylate cyclase. Pfam: MASE7 (PF20967.3), Guanylate_cyc (PF00211.26). | MASE7 Guanylate_cyc |
Resolved |
| Rv1626 Rv1626 |
mtbc0_001734 |
two-component system transcriptional regulator | ANTAR domain-containing response regulator. Pfam: Response_reg (PF00072.31), ANTAR (PF03861.20). | Response_reg ANTAR |
Family assigned |
| Rv1627c Rv1627c |
mtbc0_001735 |
nonspecific lipid-transfer protein | Lipid-transfer protein. Pfam: Thiolase_N (PF00108.30), ketoacyl-synt (PF00109.33), Thiolase_C_1 (PF22691.3). | Thiolase_N ketoacyl-synt Thiolase_C_1 |
Resolved |
| Rv1628c Rv1628c |
mtbc0_001736 |
hypothetical protein | Zn-ribbon domain-containing OB-fold protein. Pfam: zf-ChsH2 (PF12172.15), OB_ChsH2_C (PF01796.24). | zf-ChsH2 OB_ChsH2_C |
Family assigned |
| polA Rv1629 |
mtbc0_001737 |
DNA polymerase I | DNA polymerase I. Pfam: 5_3_exonuc_N (PF02739.23), 5_3_exonuc (PF01367.26), DNA_polI_exo1 (PF22619.3), DNA_pol_A (PF00476.27). | 5_3_exonuc_N 5_3_exonuc DNA_polI_exo1 DNA_pol_A |
Resolved |
| rpsA Rv1630 |
mtbc0_001738 |
30S ribosomal protein S1 | 30S ribosomal protein S1. Pfam: S1 (PF00575.30), S1_RRP5 (PF23459.2). | S1 S1_RRP5 |
Resolved |
| coaE Rv1631 |
mtbc0_001739 |
dephospho-CoA kinase CoaE | Dephospho-CoA kinase. Pfam: CoaE (PF01121.27), GrpB (PF04229.21). | CoaE GrpB |
Resolved |
| Rv1632c Rv1632c |
mtbc0_001740 |
hypothetical protein | DUF402; structure of the DUF402 family (PDB 2P12, TM 0.96); putative nucleotide-binding/phosphatase fold. | DUF402 |
Family assigned |
| uvrB Rv1633 |
- |
excinuclease ABC subunit UvrB | Excinuclease ABC subunit UvrB. Pfam: ResIII (PF04851.22), DEAD (PF00270.36), UvrB_inter (PF17757.7), UvrB_3rd (PF27431.1), Helicase_C (PF00271.38), UvrB (PF12344.15), UVR (PF02151.26). | ResIII DEAD UvrB_inter UvrB_3rd Helicase_C UvrB UVR |
Family assigned |
| Rv1634 Rv1634 |
mtbc0_001742 |
multidrug-efflux transporter | MFS transporter. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| Rv1635c Rv1635c |
mtbc0_001743 |
mannosyltransferase | Glycosyltransferase family 39 protein. | Family assigned | |
| TB15.3 Rv1636 |
mtbc0_001744 |
iron-regulated universal stress protein | Universal stress protein. Pfam: Usp (PF00582.33). | Usp |
Resolved |
| Rv1637c Rv1637c |
- |
hypothetical protein | Contains Lactamase_B (PF00753.34) domain(s); putative function inferred from the domain architecture. | Lactamase_B |
Family assigned |
| uvrA Rv1638 |
mtbc0_001746 |
excinuclease ABC subunit UvrA | Excinuclease ABC subunit UvrA. Pfam: UvrA_inter (PF17760.7), UvrA_DNA-bind (PF17755.7). | UvrA_inter UvrA_DNA-bind |
Family assigned |
| Rv1638A Rv1638A |
- |
hypothetical protein | PspA / IM30-family membrane-stress protein (eggNOG COG1842, Phage-shock-protein-A homolog that suppresses sigma54-dependent transcription), in an RD (DS6) context. Membrane-integrity stress response at family level. | Family assigned | |
| Rv1639c Rv1639c |
mtbc0_001748 |
hypothetical protein | Alpha/beta hydrolase family protein. Pfam: Esterase (PF00756.27). | Esterase |
Family assigned |
| lysX Rv1640c |
- |
bifunctional lysine--tRNA ligase/phosphatidylglycerol lysyltransferase | Bifunctional lysine--tRNA ligase/phosphatidylglycerol lysyltransferase. Pfam: tRNA-synt_2_TM (PF16995.11), LPG_synthase_C (PF09924.16), tRNA_anti-codon (PF01336.32), tRNA-synt_2 (PF00152.26). | tRNA-synt_2_TM LPG_synthase_C tRNA_anti-codon tRNA-synt_2 |
Resolved |
| infC Rv1641 |
mtbc0_001750 |
initiation factor IF-3 | Translation initiation factor IF-3. Pfam: IF3_N (PF05198.22), IF3_C (PF00707.28). | IF3_N IF3_C |
Resolved |
| rpmI Rv1642 |
- |
50S ribosomal protein L35 | 50S ribosomal protein L35. Pfam: Ribosomal_L35p (PF01632.25). | Ribosomal_L35p |
Resolved |
| rplT Rv1643 |
mtbc0_001752 |
50S ribosomal protein L20 | 50S ribosomal protein L20. Pfam: Ribosomal_L20 (PF00453.24). | Ribosomal_L20 |
Resolved |
| tsnR Rv1644 |
mtbc0_001753 |
23S rRNA methyltransferase TsnR | RNA methyltransferase. Pfam: MRM3-like_sub_bind (PF22435.2), SpoU_sub_bind (PF08032.18), SpoU_methylase (PF00588.25). | MRM3-like_sub_bind SpoU_sub_bind SpoU_methylase |
Resolved |
| Rv1645c Rv1645c |
mtbc0_001754 |
hypothetical protein | Oxygenase MpaB family protein. Pfam: MPAB_Lcp_cat (PF09995.16). | MPAB_Lcp_cat |
Family assigned |
| PE17 Rv1646 |
- |
PE family protein PE17 | PE family protein PE17. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv1647 Rv1647 |
- |
adenylate cyclase | Adenylate cyclase. Pfam: Guanylate_cyc (PF00211.26). | Guanylate_cyc |
Resolved |
| Rv1648 Rv1648 |
mtbc0_001757 |
transmembrane protein | Rhomboid-like protein. Pfam: Rhomboid_2 (PF20401.4). | Rhomboid_2 |
Family assigned |
| pheS Rv1649 |
- |
phenylalanine--tRNA ligase subunit alpha | Phenylalanine--tRNA ligase subunit alpha. Pfam: Phe_tRNA-synt_N (PF02912.24), tRNA-synt_2d (PF01409.26). | Phe_tRNA-synt_N tRNA-synt_2d |
Family assigned |
| pheT Rv1650 |
mtbc0_001759 |
phenylalanine--tRNA ligase subunit beta | Phenylalanine--tRNA ligase subunit beta. Pfam: tRNA_bind (PF01588.27), B3_4 (PF03483.23), B5 (PF03484.22), tRNA_synthFbeta (PF17759.7), FDX-ACB (PF03147.20). | tRNA_bind B3_4 B5 tRNA_synthFbeta FDX-ACB |
Family assigned |