Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2762c Rv2762c |
mtbc0_002939 |
hypothetical protein | Winged helix-turn-helix domain-containing protein. | Family assigned | |
| dfrA Rv2763c |
mtbc0_002941 |
dihydrofolate reductase | Dihydrofolate reductase. Pfam: DHFR_1 (PF00186.25). | DHFR_1 |
Resolved |
| thyA Rv2764c |
- |
thymidylate synthase ThyA | Thymidylate synthase ThyA. Pfam: Thymidylat_synt (PF00303.25). | Thymidylat_synt |
Resolved |
| Rv2765 Rv2765 |
mtbc0_002943 |
hydrolase | Dienelactone hydrolase family protein. Pfam: DLH (PF01738.25). | DLH |
Family assigned |
| Rv2766c Rv2766c |
- |
short-chain type dehydrogenase/reductase | Short-chain type dehydrogenase/reductase. Pfam: SDR (PF23441.1), adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | SDR adh_short KR adh_short_C2 |
Resolved |
| Rv2767c Rv2767c |
mtbc0_002945 |
membrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| PPE43 Rv2768c |
- |
PPE family protein PPE43 | PPE family protein PPE43. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| PE27 Rv2769c |
- |
PE family protein PE27 | PE family protein PE27. Pfam: PE (PF00934.26), PPE-SVP (PF12484.14). | PE PPE-SVP |
Family assigned |
| PPE44 Rv2770c |
- |
PPE family protein PPE44 | PPE family protein PPE44. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| Rv2771c Rv2771c |
mtbc0_002950 |
hypothetical protein | Flavodoxin family protein. | Family assigned | |
| Rv2772c Rv2772c |
mtbc0_002951 |
transmembrane protein | TPR-repeat (tetratricopeptide) protein-protein-interaction module (eggNOG COG5010/COG0457; COG category U). A scaffolding/interaction repeat protein; partners undetermined. | Family assigned | |
| dapB Rv2773c |
mtbc0_002952 |
4-hydroxy-tetrahydrodipicolinate reductase | 4-hydroxy-tetrahydrodipicolinate reductase. Pfam: DapB_N (PF01113.27), DapB_C (PF05173.20). | DapB_N DapB_C |
Resolved |
| Rv2774c Rv2774c |
mtbc0_002953 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8rrr-assembly1_E Alpha-synuclein amyloid fibril (prob 0.00, TM 0.13). | Still unknown | |
| Rv2775 Rv2775 |
- |
GCN5-like N-acetyltransferase | GCN5-like N-acetyltransferase. Pfam: Acetyltransf_10 (PF13673.14), Acetyltransf_1 (PF00583.32), Acetyltransf_7 (PF13508.14). | Acetyltransf_10 Acetyltransf_1 Acetyltransf_7 |
Resolved |
| Rv2776c Rv2776c |
- |
oxidoreductase | Oxidoreductase. Pfam: NAD_binding_1 (PF00175.27), Fer2 (PF00111.33). | NAD_binding_1 Fer2 |
Resolved |
| Rv2777c Rv2777c |
mtbc0_002956 |
hypothetical protein | Metal-dependent hydrolase. Pfam: Metal_hydrol (PF10118.15). | Metal_hydrol |
Resolved |
| Rv2778c Rv2778c |
mtbc0_002957 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv2779c Rv2779c |
- |
Lrp/AsnC family transcriptional regulator | Lrp/AsnC family transcriptional regulator. Pfam: HTH_24 (PF13412.13), HTH_AsnC-type (PF13404.13), AsnC_trans_reg (PF01037.29). | HTH_24 HTH_AsnC-type AsnC_trans_reg |
Family assigned |
| ald Rv2780 |
mtbc0_002959 |
L-alanine dehydrogenase | Alanine dehydrogenase. Pfam: AlaDh_PNT_N (PF05222.22), AlaDh_PNT_C (PF01262.28), Shikimate_DH (PF01488.27), 2-Hacid_dh_C (PF02826.26), GIDA (PF01134.29), NAD_binding_2 (PF03446.22), Pyr_redox (PF00070.34). | AlaDh_PNT_N AlaDh_PNT_C Shikimate_DH 2-Hacid_dh_C GIDA NAD_binding_2 Pyr_redox |
Resolved |
| Rv2781c Rv2781c |
mtbc0_002960 |
oxidoreductase | Nitronate monooxygenase. Pfam: NMO (PF03060.22). | NMO |
Resolved |
| pepR Rv2782c |
mtbc0_002961 |
zinc protease | Pitrilysin family protein. Pfam: Peptidase_M16 (PF00675.26), Peptidase_M16_C (PF05193.27). | Peptidase_M16 Peptidase_M16_C |
Family assigned |
| gpsI Rv2783c |
mtbc0_002962 |
bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase | Polyribonucleotide nucleotidyltransferase. Pfam: PNPase (PF03726.20), RNase_PH (PF01138.28), KH_1 (PF00013.36), S1 (PF00575.30). | PNPase RNase_PH KH_1 S1 |
Resolved |
| lppU Rv2784c |
mtbc0_002963 |
lipoprotein LppU | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| rpsO Rv2785c |
- |
30S ribosomal protein S15 | 30S ribosomal protein S15. Pfam: Ribosomal_S15 (PF00312.28). | Ribosomal_S15 |
Resolved |
| ribF Rv2786c |
- |
bifunctional riboflavin kinase /FMN adenylyltransferase | Bifunctional riboflavin kinase /FMN adenylyltransferase. Pfam: FAD_syn (PF06574.19), CTP_transf_like (PF01467.33), Flavokinase (PF01687.24). | FAD_syn CTP_transf_like Flavokinase |
Resolved |
| Rv2787 Rv2787 |
mtbc0_002966 |
hypothetical protein | AAA family ATPase. Pfam: T7SS_EccA1_N (PF21545.4), CbiA (PF01656.30). | T7SS_EccA1_N CbiA |
Family assigned |
| sirR Rv2788 |
mtbc0_002967 |
transcriptional repressor SirR | Manganese-binding transcriptional regulator MntR. Pfam: Fe_dep_repress (PF01325.26), Fe_dep_repr_C (PF02742.22), FeoA (PF04023.21). | Fe_dep_repress Fe_dep_repr_C FeoA |
Family assigned |
| fadE21 Rv2789c |
mtbc0_002968 |
acyl-CoA dehydrogenase FadE21 | Acyl-CoA dehydrogenase family protein. Pfam: Acyl-CoA_dh_M (PF02770.25), Acyl-CoA_dh_1 (PF00441.30), Acyl-CoA_dh_2 (PF08028.17). | Acyl-CoA_dh_M Acyl-CoA_dh_1 Acyl-CoA_dh_2 |
Family assigned |
| ltp1 Rv2790c |
mtbc0_002969 |
lipid-transfer protein | Lipid-transfer protein. Pfam: Thiolase_N (PF00108.30), Thiolase_C_1 (PF22691.3), Thiolase_C (PF02803.25). | Thiolase_N Thiolase_C_1 Thiolase_C |
Resolved |
| tnpB Rv2791c |
mtbc0_002970 |
transposase | IS607 family element RNA-guided endonuclease TnpB. Pfam: HTH_OrfB_IS605 (PF12323.15), OrfB_IS605 (PF01385.26). | HTH_OrfB_IS605 OrfB_IS605 |
Family assigned |
| Rv2792c Rv2792c |
mtbc0_002971 |
resolvase | IS607-like element IS1537 family transposase. Pfam: Resolvase (PF00239.27). | Resolvase |
Family assigned |
| truB Rv2793c |
mtbc0_002972 |
tRNA pseudouridine synthase B | TRNA pseudouridine(55) synthase TruB. Pfam: TruB_N (PF01509.24), TruB_C_2 (PF16198.11), TruB_C (PF09142.18). | TruB_N TruB_C_2 TruB_C |
Resolved |
| pptT Rv2794c |
mtbc0_002973 |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase. Pfam: 4PPT_N (PF17837.7), ACPS (PF01648.26). | 4PPT_N ACPS |
Resolved |
| Rv2795c Rv2795c |
mtbc0_002974 |
hypothetical protein | Metallophosphoesterase. Pfam: Metallophos (PF00149.34). | Metallophos |
Resolved |
| lppV Rv2796c |
mtbc0_002975 |
lipoprotein LppV | LppA family lipoprotein. Pfam: LppA (PF16708.11). | LppA |
Family assigned |
| Rv2797c Rv2797c |
mtbc0_002976 |
hypothetical protein | Alpha/beta hydrolase family protein. Pfam: Abhydrolase_8 (PF06259.19). | Abhydrolase_8 |
Family assigned |
| Rv2798c Rv2798c |
mtbc0_002977 |
hypothetical protein | ESAT-6-like (WXG100) / ESX-secretion family protein (EsxF-like, four-helical bundle). RefSeq leaves it 'hypothetical protein'. | Family assigned | |
| Rv2799 Rv2799 |
- |
membrane protein | Membrane protein. | Family assigned | |
| Rv2800 Rv2800 |
mtbc0_002979 |
hydrolase | CocE/NonD family hydrolase. Pfam: Peptidase_S15 (PF02129.25), PepX_C (PF08530.17). | Peptidase_S15 PepX_C |
Family assigned |
| mazE9 Rv2801A |
- |
antitoxin MazE9 | Antitoxin MazE9. | Resolved | |
| mazF9 Rv2801c |
mtbc0_002980 |
mRNA interferase MazF9 | Type II toxin-antitoxin system toxin endoribonuclease MazF9. Pfam: PemK_toxin (PF02452.24). | PemK_toxin |
Resolved |
| Rv2802c Rv2802c |
mtbc0_002982 |
arginine/hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2293. Function unknown. | DUF2293 |
Still unknown |
| Rv2803 Rv2803 |
- |
hypothetical protein | Contains TacA1 (PF08681.19) domain(s); putative function inferred from the domain architecture. | TacA1 |
Family assigned |
| Rv2804c Rv2804c |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2805 Rv2805 |
mtbc0_002985 |
hypothetical protein | Transposase. | Resolved | |
| Rv2806 Rv2806 |
mtbc0_002986 |
membrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2807 Rv2807 |
- |
hypothetical protein | Contains rve (PF00665.33) domain(s); putative function inferred from the domain architecture. | rve |
Family assigned |
| Rv2808 Rv2808 |
mtbc0_002988 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6fnd-assembly1_B Crystal structure of Toxoplasma gondii AKMT (prob 0.16, TM 0.54). | Still unknown | |
| Rv2809 Rv2809 |
mtbc0_002989 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3rrr-assembly1_B Structure of the RSV F protein in the post-fusion con (prob 0.04, TM 0.47). | Still unknown | |
| Rv2811 Rv2811 |
mtbc0_002991 |
hypothetical protein | Transposase (eggNOG COG3677, IS-family transposase; COG category L) in an RD (RDsurDR) mobile context. A mobile-element function. | Family assigned |