Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| ptrBa Rv0781 |
|
Probable protease II PtrBa [first part] (oligopeptidase B) | Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [catalytic activity: hydrolysis of ARG-|-XAA and LYS-|-XAA bonds in oligopeptides, even when P1' residue is proline]. | Peptidase_S9_N |
Family assigned |
| ptrBb Rv0782 |
|
Probable protease II PtrBb [second part] (oligopeptidase B) | Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [catalytic activity: hydrolysis of ARG-|-XAA and LYS-|-XAA bonds in oligopeptides, even when P1' residue is proline]. | Peptidase_S9 Peptidase_S9_N |
Family assigned |
| emrB Rv0783c |
mtbc0_000833 |
multidrug resistance protein EmrB | MFS transporter. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| Rv0784 Rv0784 |
- |
hypothetical protein | Carbohydrate-esterase-family-4 (CE4) / polysaccharide deacetylase (NodB-homology domain): a metal-dependent (beta/alpha)8 TIM-barrel deacetylase. The specific substrate within this functionally diverse family (peptidoglycan GlcNAc deacetylase, chitin deacetylase, or acetylxylan esterase) is undetermined. RefSeq leaves this locus uncharacterised. | DUF2334 |
Family assigned |
| Rv0785 Rv0785 |
mtbc0_000835 |
KsdD-like steroid dehydrogenase | FAD-binding dehydrogenase. Pfam: FAD_binding_3 (PF01494.26), FAD_binding_2 (PF00890.31), NAD_binding_8 (PF13450.13). | FAD_binding_3 FAD_binding_2 NAD_binding_8 |
Resolved |
| Rv0786c Rv0786c |
mtbc0_000836 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B_3 (PF13483.13), Lactamase_B (PF00753.34), Lactamase_B_2 (PF12706.14). | Lactamase_B_3 Lactamase_B Lactamase_B_2 |
Resolved |
| Rv0787 Rv0787 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 4tmd-assembly1_A X-ray structure of Putative uncharacterized protein ( (prob 0.66, TM 0.36). | Still unknown | |
| Rv0787A Rv0787A |
- |
hypothetical protein | Contains PurS (PF02700.20) domain(s); putative function inferred from the domain architecture. | PurS |
Family assigned |
| purQ Rv0788 |
mtbc0_000839 |
phosphoribosylformylglycinamidine synthase | Phosphoribosylformylglycinamidine synthase subunit PurQ. Pfam: GATase_5 (PF13507.13), GATase (PF00117.35), GATase_3 (PF07685.21), DJ-1_PfpI (PF01965.31). | GATase_5 GATase GATase_3 DJ-1_PfpI |
Family assigned |
| Rv0789c Rv0789c |
- |
hypothetical protein | YbjN-like fold (putative sensor / regulatory protein). RefSeq leaves it 'hypothetical protein'. The AlphaFold model superposes on YbjN, a putative transcription regulator (PDB 6vu7; Foldseek prob 1.0, E 1e-5, TM 0.80). Fold-level assignment; the regulatory role and partners are not established. | Family assigned | |
| Rv0790c Rv0790c |
mtbc0_000841 |
hypothetical protein | Transglutaminase-like domain-containing protein. Pfam: Transglut_core (PF01841.26). | Transglut_core |
Family assigned |
| Rv0791c Rv0791c |
mtbc0_000842 |
hypothetical protein | LLM class flavin-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv0792c Rv0792c |
mtbc0_000843 |
transcriptional regulator | GntR family transcriptional regulator. Pfam: GntR (PF00392.28), UTRA (PF07702.19). | GntR UTRA |
Family assigned |
| Rv0793 Rv0793 |
mtbc0_000844 |
monooxygenase | Putative quinol monooxygenase. Pfam: ABM (PF03992.23). | ABM |
Family assigned |
| Rv0794c Rv0794c |
- |
oxidoreductase | Oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox (PF00070.34), Pyr_redox_dim (PF02852.29). | Pyr_redox_2 Pyr_redox Pyr_redox_dim |
Resolved |
| Rv0797 Rv0797 |
- |
insertion sequence element IS1547 transposase | Insertion sequence element IS1547 transposase. Pfam: DEDD_Tnp_IS110 (PF01548.24), Transposase_20 (PF02371.23). | DEDD_Tnp_IS110 Transposase_20 |
Resolved |
| cfp29 Rv0798c |
mtbc0_000847 |
hypothetical protein | Family 1 encapsulin nanocompartment shell protein. Pfam: Linocin_M18 (PF04454.19). | Linocin_M18 |
Resolved |
| Rv0799c Rv0799c |
mtbc0_000848 |
hypothetical protein | Dyp-type peroxidase. Pfam: Dyp_perox_N (PF04261.19), Dyp_perox_C (PF20628.4). | Dyp_perox_N Dyp_perox_C |
Resolved |
| pepC Rv0800 |
mtbc0_000849 |
M18 family aminopeptidase | M18 family aminopeptidase. Pfam: Peptidase_M18 (PF02127.21). | Peptidase_M18 |
Family assigned |
| Rv0801 Rv0801 |
mtbc0_000850 |
hypothetical protein | VOC family protein. Pfam: Glyoxalase_6 (PF18029.8), Glyoxalase (PF00903.32). | Glyoxalase_6 Glyoxalase |
Family assigned |
| Rv0802c Rv0802c |
mtbc0_000851 |
succinyl-CoA transferase | GNAT family protein. Pfam: Acetyltransf_3 (PF13302.14). | Acetyltransf_3 |
Family assigned |
| purL Rv0803 |
mtbc0_000852 |
phosphoribosylformylglycinamidine synthase 2 | Phosphoribosylformylglycinamidine synthase subunit PurL. Pfam: FGAR-AT_linker (PF18072.7), AIRS (PF00586.30), AIRS_C (PF02769.28). | FGAR-AT_linker AIRS AIRS_C |
Family assigned |
| Rv0804 Rv0804 |
mtbc0_000853 |
hypothetical protein | CPBP family intramembrane glutamic endopeptidase. Pfam: Rce1-like (PF02517.22). | Rce1-like |
Family assigned |
| cpdA Rv0805 |
mtbc0_000854 |
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA | 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA. Pfam: Metallophos (PF00149.34). | Metallophos |
Resolved |
| cpsY Rv0806c |
mtbc0_000855 |
exopolysaccharide phosphotransferase CpsY | Stealth family protein. Pfam: Stealth_CR1 (PF17101.11), Stealth_CR2 (PF11380.14), Stealth_CR3 (PF17102.11), Stealth_CR4 (PF17103.11). | Stealth_CR1 Stealth_CR2 Stealth_CR3 Stealth_CR4 |
Family assigned |
| Rv0807 Rv0807 |
mtbc0_000856 |
hypothetical protein | Sterol carrier family protein. Pfam: SCP_3 (PF17844.7). | SCP_3 |
Family assigned |
| purF Rv0808 |
- |
amidophosphoribosyltransferase | Amidophosphoribosyltransferase. Pfam: GATase_6 (PF13522.12), GATase_7 (PF13537.12), Pribosyltran (PF00156.34). | GATase_6 GATase_7 Pribosyltran |
Resolved |
| purM Rv0809 |
mtbc0_000858 |
phosphoribosylformylglycinamidine cyclo-ligase PurM | Phosphoribosylformylglycinamidine cyclo-ligase. Pfam: AIRS (PF00586.30), AIRS_C (PF02769.28). | AIRS AIRS_C |
Resolved |
| Rv0810c Rv0810c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF3073. Function unknown. | DUF3073 |
Still unknown |
| Rv0811c Rv0811c |
mtbc0_000860 |
hypothetical protein | Folate-binding protein YgfZ. | Family assigned | |
| Rv0812 Rv0812 |
- |
4-amino-4-deoxychorismate lyase | 4-amino-4-deoxychorismate lyase. Pfam: Aminotran_4 (PF01063.25). | Aminotran_4 |
Resolved |
| Rv0813c Rv0813c |
mtbc0_000862 |
hypothetical protein | FABP family protein. Pfam: THAP4_heme-bd (PF08768.18). | THAP4_heme-bd |
Family assigned |
| Rv0814c Rv0814c |
mtbc0_000863 |
hypothetical protein | DUF1416 domain-containing protein. Pfam: DUF1416 (PF07210.19), CarboxypepD_reg (PF13620.13). | DUF1416 CarboxypepD_reg |
Family assigned |
| cysA2 Rv0815c |
mtbc0_000864 |
thiosulfate sulfurtransferase CysA | Sulfurtransferase. Pfam: Rhodanese (PF00581.26). | Rhodanese |
Resolved |
| thiX Rv0816c |
mtbc0_000865 |
thioredoxin ThiX | Thioredoxin family protein. Pfam: Thioredoxin (PF00085.27). | Thioredoxin |
Family assigned |
| lmeA Rv0817c |
mtbc0_000866 |
hypothetical protein | Mannan chain length control protein LmeA. Pfam: LmeA (PF11209.14). | LmeA |
Resolved |
| Rv0818 Rv0818 |
mtbc0_000867 |
transcriptional regulator | Response regulator transcription factor. Pfam: GlnR_1st (PF21695.4), Trans_reg_C (PF00486.35). | GlnR_1st Trans_reg_C |
Resolved |
| mshD Rv0819 |
mtbc0_000868 |
mycothiol acetyltransferase | Mycothiol synthase. Pfam: Acetyltransf_1 (PF00583.32), Acetyltransf_7 (PF13508.14). | Acetyltransf_1 Acetyltransf_7 |
Resolved |
| phoT Rv0820 |
mtbc0_000869 |
phosphate ABC transporter ATP-binding protein PhoT | Phosphate ABC transporter ATP-binding protein PstB. Pfam: ABC_tran (PF00005.34). | ABC_tran |
Family assigned |
| phoY2 Rv0821c |
mtbc0_000870 |
phosphate-transport system transcriptional regulator PhoY2 | Phosphate signaling complex protein PhoU. Pfam: PhoU (PF01895.25). | PhoU |
Resolved |
| Rv0822c Rv0822c |
mtbc0_000871 |
hypothetical protein | LCP family protein. Pfam: LytR_cpsA_psr (PF03816.20), LytR_C (PF13399.12). | LytR_cpsA_psr LytR_C |
Family assigned |
| dusB Rv0823c |
mtbc0_000872 |
tRNA-dihydrouridine synthase | TRNA dihydrouridine synthase DusB. Pfam: Dus (PF01207.24). | Dus |
Resolved |
| desA1 Rv0824c |
- |
acyl-ACP desaturase DesA | Acyl-ACP desaturase DesA. Pfam: FA_desaturase_2 (PF03405.21). | FA_desaturase_2 |
Resolved |
| Rv0825c Rv0825c |
mtbc0_000874 |
hypothetical protein | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30). | TetR_N |
Family assigned |
| Rv0826 Rv0826 |
mtbc0_000875 |
hypothetical protein | Oxygenase MpaB family protein. Pfam: MPAB_Lcp_cat (PF09995.16). | MPAB_Lcp_cat |
Family assigned |
| kmtR Rv0827c |
mtbc0_000876 |
HTH-type transcriptional regulator KmtR | Ni(II)/Co(II)-sensing metalloregulatory transcriptional repressor KmtR. Pfam: HTH_20 (PF12840.14), HTH_5 (PF01022.27), MarR_2 (PF12802.14), HTH_IclR (PF09339.17). | HTH_20 HTH_5 MarR_2 HTH_IclR |
Resolved |
| Rv0828c Rv0828c |
- |
deaminase | Deaminase. Pfam: dCMP_cyt_deam_1 (PF00383.30), MafB19-deam (PF14437.13). | dCMP_cyt_deam_1 MafB19-deam |
Resolved |
| Rv0830 Rv0830 |
mtbc0_000879 |
S-adenosylmethionine-dependent methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| Rv0831c Rv0831c |
mtbc0_000880 |
hypothetical protein | TIGR04255 family protein. | Family assigned | |
| PE_PGRS12 Rv0832 |
- |
PE-PGRS family protein PE_PGRS12 | PE-PGRS family protein PE_PGRS12. Pfam: PE (PF00934.26). | PE |
Family assigned |