Genes
1051 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1518 Rv1518 |
mtbc0_001625 |
hypothetical protein | Glycosyltransferase. Pfam: Glyco_tranf_2_3 (PF13641.13), Glycos_transf_2 (PF00535.33). | Glyco_tranf_2_3 Glycos_transf_2 |
Resolved |
| Rv1519 Rv1519 |
- |
hypothetical protein | Contains DegT_DnrJ_EryC1 (PF01041.24) domain(s); putative function inferred from the domain architecture. | DegT_DnrJ_EryC1 |
Family assigned |
| Rv1531 Rv1531 |
mtbc0_001638 |
hypothetical protein | Carboxymuconolactone decarboxylase family protein. Pfam: CMD (PF02627.26). | CMD |
Family assigned |
| Rv1532c Rv1532c |
mtbc0_001639 |
hypothetical protein | PaaI family thioesterase. Pfam: DUF4442 (PF14539.13), 4HBT (PF03061.29). | DUF4442 4HBT |
Family assigned |
| Rv1535 Rv1535 |
mtbc0_001642 |
hypothetical protein | Rv1535 family protein. | Family assigned | |
| Rv1545 Rv1545 |
mtbc0_001652 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3cht-assembly1_B Crystal Structure of Di-iron AurF with partially boun (prob 0.03, TM 0.23). | Still unknown | |
| Rv1546 Rv1546 |
mtbc0_001653 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1558 Rv1558 |
mtbc0_001666 |
hypothetical protein | F420H(2)-dependent quinone reductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Resolved |
| ripD Rv1566c |
mtbc0_001674 |
hypothetical protein | NlpC/P60 family peptidoglycan-binding protein RipD. Pfam: NLPC_P60 (PF00877.26). | NLPC_P60 |
Family assigned |
| Rv1571 Rv1571 |
mtbc0_001679 |
hypothetical protein | 2'-5' RNA ligase family protein. Pfam: 2_5_RNA_ligase2 (PF13563.13). | 2_5_RNA_ligase2 |
Family assigned |
| Rv1587c Rv1587c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF222. Function unknown. Foldseek best (non-significant) hit: 4h9d-assembly1_B Crystal Structure of Mn-dependent Gme HNH nicking end (prob 0.23, TM 0.72). | DUF222 |
Still unknown |
| Rv1588c Rv1588c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF222. Function unknown. Foldseek best (non-significant) hit: 2qww-assembly3_F Crystal structure of multiple antibiotic-resistance r (prob 0.18, TM 0.26). | DUF222 |
Still unknown |
| Rv1590 Rv1590 |
mtbc0_001696 |
hypothetical protein | Contains BsaP (PF26519.1) domain(s); putative function inferred from the domain architecture. | BsaP |
Family assigned |
| Rv1592c Rv1592c |
mtbc0_001698 |
hypothetical protein | Lipase family protein. Pfam: LIP (PF03583.21). | LIP |
Family assigned |
| Rv1593c Rv1593c |
mtbc0_001699 |
hypothetical protein | NUDIX domain-containing protein. Pfam: NUDIX (PF00293.35), WHD_AraR (PF19368.6), WHD_NrtR (PF21906.3). | NUDIX WHD_AraR WHD_NrtR |
Family assigned |
| Rv1597 Rv1597 |
mtbc0_001703 |
hypothetical protein | Methyltransferase domain-containing protein. Pfam: Methyltransf_11 (PF08241.19). | Methyltransf_11 |
Family assigned |
| Rv1598c Rv1598c |
mtbc0_001704 |
hypothetical protein | Nitroreductase family deazaflavin-dependent oxidoreductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Family assigned |
| Rv1616 Rv1616 |
mtbc0_001723 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | DUF2752 |
Family assigned |
| Rv1619 Rv1619 |
mtbc0_001726 |
hypothetical protein | Bifunctional lysylphosphatidylglycerol flippase/synthetase MprF. Pfam: LPG_synthase_C (PF09924.16). | LPG_synthase_C |
Resolved |
| Rv1628c Rv1628c |
mtbc0_001736 |
hypothetical protein | Zn-ribbon domain-containing OB-fold protein. Pfam: zf-ChsH2 (PF12172.15), OB_ChsH2_C (PF01796.24). | zf-ChsH2 OB_ChsH2_C |
Family assigned |
| Rv1632c Rv1632c |
mtbc0_001740 |
hypothetical protein | DUF402; structure of the DUF402 family (PDB 2P12, TM 0.96); putative nucleotide-binding/phosphatase fold. | DUF402 |
Family assigned |
| Rv1637c Rv1637c |
- |
hypothetical protein | Contains Lactamase_B (PF00753.34) domain(s); putative function inferred from the domain architecture. | Lactamase_B |
Family assigned |
| Rv1638A Rv1638A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1639c Rv1639c |
mtbc0_001748 |
hypothetical protein | Alpha/beta hydrolase family protein. Pfam: Esterase (PF00756.27). | Esterase |
Family assigned |
| Rv1645c Rv1645c |
mtbc0_001754 |
hypothetical protein | Oxygenase MpaB family protein. Pfam: MPAB_Lcp_cat (PF09995.16). | MPAB_Lcp_cat |
Family assigned |
| Rv1669 Rv1669 |
mtbc0_001776 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3jsy-assembly2_B N-terminal fragment of ribosomal protein L10 from Met (prob 0.10, TM 0.55). | Still unknown | |
| Rv1670 Rv1670 |
mtbc0_001777 |
hypothetical protein | DUF427 domain-containing protein. Pfam: NTP_transf_9 (PF04248.20). | NTP_transf_9 |
Family assigned |
| Rv1673c Rv1673c |
mtbc0_001780 |
hypothetical protein | Transglutaminase family protein. Pfam: Transglut_core (PF01841.26). | Transglut_core |
Family assigned |
| Rv1676 Rv1676 |
mtbc0_001784 |
hypothetical protein | Peroxiredoxin-like family protein. Pfam: AhpC-TSA (PF00578.28), AhpC-TSA_2 (PF13911.13). | AhpC-TSA AhpC-TSA_2 |
Family assigned |
| Rv1680 Rv1680 |
mtbc0_001788 |
hypothetical protein | Phosphate/phosphite/phosphonate ABC transporter substrate-binding protein. Pfam: Phosphonate-bd (PF12974.13). | Phosphonate-bd |
Family assigned |
| Rv1682 Rv1682 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8sf7-assembly1_1O 48-nm doublet microtubule from Tetrahymena thermophi (prob 0.02, TM 0.26). | Still unknown | |
| Rv1684 Rv1684 |
mtbc0_001792 |
hypothetical protein | Trm112 family protein. Pfam: Trm112p (PF03966.23). | Trm112p |
Family assigned |
| Rv1685c Rv1685c |
mtbc0_001793 |
hypothetical protein | TetR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_16 (PF17920.7). | TetR_N TetR_C_16 |
Family assigned |
| Rv1691 Rv1691 |
mtbc0_001799 |
hypothetical protein | TPR-repeat fold (PDB 2PL2); putative protein-protein-interaction scaffold. | Family assigned | |
| Rv1693 Rv1693 |
mtbc0_001801 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3dxr-assembly1_B Crystal structure of the yeast inter-membrane space c (prob 0.44, TM 0.55). | Still unknown | |
| steA Rv1697 |
mtbc0_001805 |
hypothetical protein | Putative cytokinetic ring protein SteA. Pfam: SteA-like_C (PF12555.14). | SteA-like_C |
Family assigned |
| Rv1702c Rv1702c |
mtbc0_001810 |
hypothetical protein | HNH endonuclease signature motif containing protein. | DUF222 |
Resolved |
| Rv1706A Rv1706A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3q1p-assembly1_B Crystal structure of CDP-Chase (prob 0.41, TM 0.85). | Still unknown | |
| Rv1716 Rv1716 |
- |
hypothetical protein | Contains Cyclase (PF04199.20) domain(s); putative function inferred from the domain architecture. | Cyclase |
Family assigned |
| Rv1717 Rv1717 |
mtbc0_001827 |
hypothetical protein | Cupin domain-containing protein. Pfam: Cupin_2 (PF07883.18). | Cupin_2 |
Family assigned |
| Rv1718 Rv1718 |
mtbc0_001828 |
hypothetical protein | 3-keto-5-aminohexanoate cleavage protein. Pfam: BKACE (PF05853.19). | BKACE |
Resolved |
| Rv1724c Rv1724c |
mtbc0_001836 |
hypothetical protein | Conserved hypothetical; Foldseek hits non-conclusive (moderate TM). Function unknown. | Still unknown | |
| Rv1725c Rv1725c |
mtbc0_001837 |
hypothetical protein | Winged helix-turn-helix transcriptional regulator. Pfam: HxlR (PF01638.24). | HxlR |
Family assigned |
| Rv1727 Rv1727 |
mtbc0_001839 |
hypothetical protein | TIGR03086 family metal-binding protein. Pfam: MDMPI_N (PF11716.14). | MDMPI_N |
Family assigned |
| Rv1728c Rv1728c |
mtbc0_001840 |
hypothetical protein | Glycoside hydrolase. Pfam: VldE (PF26571.1). | VldE |
Resolved |
| Rv1732c Rv1732c |
mtbc0_001844 |
hypothetical protein | Thioredoxin family protein. Pfam: AhpC-TSA (PF00578.28), Redoxin (PF08534.17). | AhpC-TSA Redoxin |
Family assigned |
| Rv1734c Rv1734c |
- |
hypothetical protein | Contains 2-oxoacid_dh (PF00198.29) domain(s); putative function inferred from the domain architecture. | 2-oxoacid_dh |
Family assigned |
| Rv1735a Rv1735a |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1738 Rv1738 |
mtbc0_001851 |
hypothetical protein | DUF1876 domain-containing protein. Pfam: Rv2632c-like (PF08962.17). | Rv2632c-like |
Family assigned |
| Rv1742 Rv1742 |
mtbc0_001855 |
hypothetical protein | LolA-superfamily fold (lipoprotein / lipid carrier-like beta-barrel). RefSeq leaves it 'hypothetical protein'. The AlphaFold model superposes on a LolA-superfamily protein (PDB 3buu; Foldseek prob 1.0, E 3e-8, TM 0.57). STRING context: the toxin vapC34 (Rv1741). A carrier/periplasmic-binding fold; the cargo is undemonstrated. | Family assigned |