Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1829 Rv1829 |
- |
hypothetical protein | Contains BFN_dom (PF02577.20) domain(s); putative function inferred from the domain architecture. | BFN_dom |
Family assigned |
| Rv1830 Rv1830 |
- |
HTH-type transcriptional regulator | HTH-type transcriptional regulator. Pfam: MerR_1 (PF13411.13). | MerR_1 |
Family assigned |
| Rv1831 Rv1831 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| gcvB Rv1832 |
mtbc0_001945 |
glycine dehydrogenase | Aminomethyl-transferring glycine dehydrogenase. Pfam: GDC-P (PF02347.23), GcvP2_C (PF21478.4). | GDC-P GcvP2_C |
Resolved |
| Rv1833c Rv1833c |
mtbc0_001946 |
haloalkane dehalogenase | Haloalkane dehalogenase. Pfam: Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14), Hydrolase_4 (PF12146.16). | Abhydrolase_1 Abhydrolase_6 Hydrolase_4 |
Resolved |
| lipZ Rv1834 |
mtbc0_001947 |
hydrolase | Alpha/beta hydrolase. Pfam: Abhydrolase_1 (PF00561.27), Hydrolase_4 (PF12146.16), Abhydrolase_6 (PF12697.14). | Abhydrolase_1 Hydrolase_4 Abhydrolase_6 |
Family assigned |
| Rv1835c Rv1835c |
mtbc0_001948 |
serine esterase | CocE/NonD family hydrolase. Pfam: Peptidase_S15 (PF02129.25), PepX_C (PF08530.17). | Peptidase_S15 PepX_C |
Family assigned |
| Rv1836c Rv1836c |
mtbc0_001949 |
hypothetical protein | Substrate-binding domain-containing protein. Pfam: SBP_bac_11 (PF13531.12). | SBP_bac_11 |
Family assigned |
| glcB Rv1837c |
mtbc0_001950 |
malate synthase | Malate synthase G. Pfam: MS_N (PF20656.3), MSG_insertion (PF20658.3), MS_TIM-barrel (PF01274.29), MS_C (PF20659.3). | MS_N MSG_insertion MS_TIM-barrel MS_C |
Resolved |
| vapC13 Rv1838c |
mtbc0_001951 |
ribonuclease VapC13 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| vapB13 Rv1839c |
mtbc0_001952 |
antitoxin VapB13 | Antitoxin. | Resolved | |
| PE_PGRS34 Rv1840c |
- |
PE-PGRS family protein PE_PGRS34 | PE-PGRS family protein PE_PGRS34. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| Rv1841c Rv1841c |
mtbc0_001954 |
hypothetical protein | Hemolysin family protein. Pfam: CNNM (PF01595.26), CBS (PF00571.34). | CNNM CBS |
Family assigned |
| Rv1842c Rv1842c |
mtbc0_001955 |
hypothetical protein | Hemolysin family protein. Pfam: CNNM (PF01595.26), CBS (PF00571.34), CorC_HlyC (PF03471.23). | CNNM CBS CorC_HlyC |
Family assigned |
| guaB1 Rv1843c |
mtbc0_001956 |
inosine-5'-monophosphate dehydrogenase | GuaB1 family IMP dehydrogenase-related protein. Pfam: IMPDH (PF00478.32), CBS (PF00571.34). | IMPDH CBS |
Family assigned |
| gnd1 Rv1844c |
- |
6-phosphogluconate dehydrogenase | 6-phosphogluconate dehydrogenase. Pfam: NAD_binding_2 (PF03446.22), 6PGD (PF00393.25). | NAD_binding_2 6PGD |
Resolved |
| blaR Rv1845c |
mtbc0_001958 |
sensor-transducer protein BlaR | M56 family metallopeptidase. Pfam: Peptidase_M48 (PF01435.25). | Peptidase_M48 |
Family assigned |
| blaI Rv1846c |
mtbc0_001959 |
transcriptional repressor BlaI | Transcriptional repressor BlaI. Pfam: Penicillinase_R (PF03965.23). | Penicillinase_R |
Resolved |
| Rv1847 Rv1847 |
mtbc0_001960 |
esterase | PaaI family thioesterase. Pfam: DUF4442 (PF14539.13), 4HBT (PF03061.29). | DUF4442 4HBT |
Family assigned |
| ureA Rv1848 |
mtbc0_001961 |
urease subunit gamma | Urease subunit gamma. Pfam: Urease_gamma (PF00547.24). | Urease_gamma |
Family assigned |
| ureB Rv1849 |
mtbc0_001962 |
urease subunit beta | Urease subunit beta. Pfam: Urease_beta (PF00699.26). | Urease_beta |
Family assigned |
| ureC Rv1850 |
mtbc0_001963 |
urease subunit alpha | Urease subunit alpha. Pfam: Urease_alpha (PF00449.27), Amidohydro_1 (PF01979.27). | Urease_alpha Amidohydro_1 |
Family assigned |
| ureF Rv1851 |
mtbc0_001964 |
urease accessory protein UreF | Urease accessory protein UreF. Pfam: UreF (PF01730.22). | UreF |
Resolved |
| ureG Rv1852 |
mtbc0_001965 |
urease accessory protein UreG | Urease accessory protein UreG. Pfam: cobW (PF02492.26). | cobW |
Resolved |
| ureD Rv1853 |
- |
urease accessory protein UreD | Urease accessory protein UreD. Pfam: UreD (PF01774.23). | UreD |
Resolved |
| ndh Rv1854c |
mtbc0_001967 |
NADH dehydrogenase | NAD(P)/FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox (PF00070.34). | Pyr_redox_2 Pyr_redox |
Resolved |
| Rv1855c Rv1855c |
mtbc0_001968 |
oxidoreductase | LLM class F420-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv1856c Rv1856c |
mtbc0_001969 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| modA Rv1857 |
mtbc0_001970 |
molybdate ABC transporter substrate-binding lipoprotein ModA | Molybdate ABC transporter substrate-binding protein. Pfam: SBP_bac_11 (PF13531.12), SBP_bac_1 (PF01547.31). | SBP_bac_11 SBP_bac_1 |
Family assigned |
| modB Rv1858 |
mtbc0_001971 |
molybdenum ABC transporter permease ModB | ABC transporter permease. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| modC Rv1859 |
mtbc0_001972 |
molybdenum ABC transporter ATP-binding protein ModC | Sulfate/molybdate ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34), TOBE (PF03459.24). | ABC_tran TOBE |
Family assigned |
| apa Rv1860 |
- |
hypothetical protein | Contains FAP (PF07174.18) domain(s); putative function inferred from the domain architecture. | FAP |
Family assigned |
| Rv1861 Rv1861 |
mtbc0_001974 |
transmembrane protein | GlsB/YeaQ/YmgE family stress response membrane protein. Pfam: Transgly_assoc (PF04226.19). | Transgly_assoc |
Family assigned |
| adhA Rv1862 |
mtbc0_001975 |
alcohol dehydrogenase A | Zinc-binding alcohol dehydrogenase family protein. Pfam: ADH_N (PF08240.18). | ADH_N |
Family assigned |
| Rv1863c Rv1863c |
- |
integral membrane protein | Integral membrane protein. Pfam: Rce1-like (PF02517.22). | Rce1-like |
Family assigned |
| Rv1864c Rv1864c |
- |
hypothetical protein | Contains MOSC (PF03473.24) domain(s); putative function inferred from the domain architecture. | MOSC |
Family assigned |
| Rv1865c Rv1865c |
mtbc0_001978 |
short-chain type dehydrogenase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| Rv1866 Rv1866 |
- |
hypothetical protein | Contains CoA_transf_3 (PF02515.23) domain(s); putative function inferred from the domain architecture. | CoA_transf_3 |
Family assigned |
| Rv1867 Rv1867 |
mtbc0_001980 |
hypothetical protein | Acetyl-CoA acetyltransferase. Pfam: TLP1_add_C (PF18313.8). | TLP1_add_C |
Resolved |
| Rv1868 Rv1868 |
mtbc0_001981 |
hypothetical protein | NAD(P)H-binding protein. Pfam: Rph_4th (PF27448.1). | Rph_4th |
Family assigned |
| Rv1869c Rv1869c |
mtbc0_001982 |
reductase | FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox_3 (PF13738.13), Pyr_redox (PF00070.34), Reductase_C (PF14759.13). | Pyr_redox_2 Pyr_redox_3 Pyr_redox Reductase_C |
Resolved |
| Rv1870c Rv1870c |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 4uob-assembly1_A Crystal structure of Deinococcus radiodurans Endonuclease III-3 (prob 1.00, TM 0.56). Structure-based, putative. | Family assigned | |
| Rv1871c Rv1871c |
mtbc0_001984 |
hypothetical protein | Nitroreductase family deazaflavin-dependent oxidoreductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Family assigned |
| lldD2 Rv1872c |
mtbc0_001985 |
L-lactate dehydrogenase | Quinone-dependent L-lactate dehydrogenase. Pfam: FMN_dh (PF01070.25). | FMN_dh |
Resolved |
| Rv1873 Rv1873 |
mtbc0_001986 |
hypothetical protein | Conserved hypothetical protein with an X-ray crystal structure at 1.38 A: a 16.2 kDa monomer adopting a primarily alpha-helical fold with limited similarity to known structures (COG5579). Not a novel fold but a model for sequence-related orthologues. Function unknown. (The UniProt auto-name 'Calpastatin' is a database artefact and is not adopted.) | DUF1810 |
Family assigned |
| Rv1874 Rv1874 |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2ftr-assembly1_B Crystal structure of an ethyl tert-butyl ether d (ethd) family (prob 1.00, TM 0.62). Structure-based, putative. | Family assigned | |
| Rv1875 Rv1875 |
mtbc0_001988 |
hypothetical protein | PPOX class F420-dependent oxidoreductase. Pfam: PNPOx_N (PF01243.28). | PNPOx_N |
Resolved |
| bfrA Rv1876 |
- |
bacterioferritin BfrA | Bacterioferritin BfrA. Pfam: Ferritin (PF00210.31). | Ferritin |
Resolved |
| Rv1877 Rv1877 |
mtbc0_001991 |
MFS-type transporter | MDR family MFS transporter. Pfam: MFS_1 (PF07690.22), TRI12 (PF06609.19), Sugar_tr (PF00083.31). | MFS_1 TRI12 Sugar_tr |
Family assigned |
| glnA3 Rv1878 |
mtbc0_001992 |
glutamine synthetase GlnA | Glutamine synthetase family protein. Pfam: Gln-synt_C (PF00120.30). | Gln-synt_C |
Family assigned |