Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| modC Rv1859 |
mtbc0_001972 |
molybdenum ABC transporter ATP-binding protein ModC | Sulfate/molybdate ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34), TOBE (PF03459.24). | ABC_tran TOBE |
Family assigned |
| apa Rv1860 |
- |
hypothetical protein | Contains FAP (PF07174.18) domain(s); putative function inferred from the domain architecture. | FAP |
Family assigned |
| Rv1861 Rv1861 |
mtbc0_001974 |
transmembrane protein | GlsB/YeaQ/YmgE family stress response membrane protein. Pfam: Transgly_assoc (PF04226.19). | Transgly_assoc |
Family assigned |
| adhA Rv1862 |
mtbc0_001975 |
alcohol dehydrogenase A | Zinc-binding alcohol dehydrogenase family protein. Pfam: ADH_N (PF08240.18). | ADH_N |
Family assigned |
| Rv1863c Rv1863c |
- |
integral membrane protein | Integral membrane protein. Pfam: Rce1-like (PF02517.22). | Rce1-like |
Family assigned |
| Rv1864c Rv1864c |
- |
hypothetical protein | Contains MOSC (PF03473.24) domain(s); putative function inferred from the domain architecture. | MOSC |
Family assigned |
| Rv1865c Rv1865c |
mtbc0_001978 |
short-chain type dehydrogenase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| Rv1866 Rv1866 |
- |
hypothetical protein | Contains CoA_transf_3 (PF02515.23) domain(s); putative function inferred from the domain architecture. | CoA_transf_3 |
Family assigned |
| Rv1867 Rv1867 |
mtbc0_001980 |
hypothetical protein | Acetyl-CoA acetyltransferase. Pfam: TLP1_add_C (PF18313.8). | TLP1_add_C |
Resolved |
| Rv1868 Rv1868 |
mtbc0_001981 |
hypothetical protein | NAD(P)H-binding protein. Pfam: Rph_4th (PF27448.1). | Rph_4th |
Family assigned |
| Rv1869c Rv1869c |
mtbc0_001982 |
reductase | FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox_3 (PF13738.13), Pyr_redox (PF00070.34), Reductase_C (PF14759.13). | Pyr_redox_2 Pyr_redox_3 Pyr_redox Reductase_C |
Resolved |
| Rv1870c Rv1870c |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 4uob-assembly1_A Crystal structure of Deinococcus radiodurans Endonuclease III-3 (prob 1.00, TM 0.56). Structure-based, putative. | Family assigned | |
| Rv1871c Rv1871c |
mtbc0_001984 |
hypothetical protein | Nitroreductase family deazaflavin-dependent oxidoreductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Family assigned |
| lldD2 Rv1872c |
mtbc0_001985 |
L-lactate dehydrogenase | Quinone-dependent L-lactate dehydrogenase. Pfam: FMN_dh (PF01070.25). | FMN_dh |
Resolved |
| Rv1873 Rv1873 |
mtbc0_001986 |
hypothetical protein | Conserved hypothetical protein with an X-ray crystal structure at 1.38 A: a 16.2 kDa monomer adopting a primarily alpha-helical fold with limited similarity to known structures (COG5579). Not a novel fold but a model for sequence-related orthologues. Function unknown. (The UniProt auto-name 'Calpastatin' is a database artefact and is not adopted.) | DUF1810 |
Family assigned |
| Rv1874 Rv1874 |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2ftr-assembly1_B Crystal structure of an ethyl tert-butyl ether d (ethd) family (prob 1.00, TM 0.62). Structure-based, putative. | Family assigned | |
| Rv1875 Rv1875 |
mtbc0_001988 |
hypothetical protein | PPOX class F420-dependent oxidoreductase. Pfam: PNPOx_N (PF01243.28). | PNPOx_N |
Resolved |
| bfrA Rv1876 |
- |
bacterioferritin BfrA | Bacterioferritin BfrA. Pfam: Ferritin (PF00210.31). | Ferritin |
Resolved |
| Rv1877 Rv1877 |
mtbc0_001991 |
MFS-type transporter | MDR family MFS transporter. Pfam: MFS_1 (PF07690.22), TRI12 (PF06609.19), Sugar_tr (PF00083.31). | MFS_1 TRI12 Sugar_tr |
Family assigned |
| glnA3 Rv1878 |
mtbc0_001992 |
glutamine synthetase GlnA | Glutamine synthetase family protein. Pfam: Gln-synt_C (PF00120.30). | Gln-synt_C |
Family assigned |
| Rv1879 Rv1879 |
mtbc0_001993 |
hypothetical protein | Amidohydrolase family protein. Pfam: Amidohydro_2 (PF04909.21). | Amidohydro_2 |
Family assigned |
| cyp140 Rv1880c |
mtbc0_001994 |
cytochrome P450 Cyp140 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| lppE Rv1881c |
mtbc0_001995 |
lipoprotein LppE | Lipoprotein LpqH. Pfam: Myco_19_kDa (PF05481.18). | Myco_19_kDa |
Resolved |
| Rv1882c Rv1882c |
mtbc0_001996 |
short-chain type dehydrogenase/reductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| Rv1883c Rv1883c |
mtbc0_001997 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16), Polyketide_cyc (PF03364.26). | Polyketide_cyc2 Polyketide_cyc |
Family assigned |
| rpfC Rv1884c |
mtbc0_001998 |
resuscitation-promoting factor RpfC | Resuscitation-promoting factor RpfC. Pfam: Transglycosylas (PF06737.20). | Transglycosylas |
Resolved |
| Rv1885c Rv1885c |
mtbc0_001999 |
chorismate mutase | Chorismate mutase. Pfam: CM_2 (PF01817.27). | CM_2 |
Resolved |
| fbpB Rv1886c |
mtbc0_002000 |
diacylglycerol acyltransferase/mycolyltransferase Ag85B | Diacylglycerol acyltransferase/mycolyltransferase Ag85B. Pfam: Esterase (PF00756.27). | Esterase |
Resolved |
| Rv1887 Rv1887 |
mtbc0_002001 |
hypothetical protein | Exopolyphosphatase-like fold (PDB 3HI0); putative phosphatase/hydrolase. | DUF7159 |
Family assigned |
| Rv1890c Rv1890c |
- |
hypothetical protein | Contains YceI (PF04264.19) domain(s); putative function inferred from the domain architecture. | YceI |
Family assigned |
| Rv1891 Rv1891 |
mtbc0_002005 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6xl5-assembly1_D Cryo-EM structure of EcmrR-RNAP-promoter open complex (prob 0.04, TM 0.37). | Still unknown | |
| Rv1892 Rv1892 |
mtbc0_002006 |
membrane protein | Small integral membrane protein under strong purifying selection (pN/pS 0). Its fold WEAKLY resembles actinobacterial respiratory-supercomplex accessory subunits (HHpred 7E1V/7Q21, E~1-2, near the TM-helix promiscuity floor). Function undetermined; the supercomplex association is a weak structural hint only, uncorroborated. | Family assigned | |
| Rv1893 Rv1893 |
mtbc0_002007 |
hypothetical protein | Contains Rv1893 (PF23706.3) domain(s); putative function inferred from the domain architecture. | Rv1893 |
Family assigned |
| Rv1894c Rv1894c |
mtbc0_002008 |
hypothetical protein | Nitronate monooxygenase family protein. Pfam: NMO (PF03060.22). | NMO |
Family assigned |
| Rv1895 Rv1895 |
- |
zinc-binding alcohol dehydrogenase | Zinc-binding alcohol dehydrogenase. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | ADH_N ADH_zinc_N ADH_zinc_N_2 |
Resolved |
| Rv1896c Rv1896c |
mtbc0_002010 |
S-adenosyl-L-methionine-dependent methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| dtd Rv1897c |
mtbc0_002011 |
D-tyrosyl-tRNA(Tyr) deacylase | D-aminoacyl-tRNA deacylase. Pfam: Tyr_Deacylase (PF02580.22). | Tyr_Deacylase |
Resolved |
| Rv1898 Rv1898 |
mtbc0_002012 |
hypothetical protein | MTH1187 family thiamine-binding protein. Pfam: Thiamine_BP (PF01910.23). | Thiamine_BP |
Family assigned |
| lppD Rv1899c |
- |
lipoprotein LppD | Lipoprotein LppD. Pfam: Macro (PF01661.28). | Macro |
Resolved |
| lipJ Rv1900c |
mtbc0_002015 |
lignin peroxidase LipJ | Adenylate/guanylate cyclase domain-containing protein. Pfam: Abhydrolase_1 (PF00561.27), Guanylate_cyc (PF00211.26). | Abhydrolase_1 Guanylate_cyc |
Family assigned |
| cinA Rv1901 |
mtbc0_002016 |
competence damage-inducible protein CinA | Competence/damage-inducible protein A. Pfam: MoCF_biosynth (PF00994.30), CinA (PF02464.24). | MoCF_biosynth CinA |
Resolved |
| nanT Rv1902c |
mtbc0_002017 |
sialic acid-transport integral membrane protein NanT | Sialate:H+ symport family MFS transporter. Pfam: Sugar_tr (PF00083.31), MFS_1 (PF07690.22). | Sugar_tr MFS_1 |
Family assigned |
| Rv1903 Rv1903 |
mtbc0_002018 |
membrane protein | Phage holin family protein. Pfam: Phage_holin_4_2 (PF04020.19). | Phage_holin_4_2 |
Family assigned |
| Rv1904 Rv1904 |
mtbc0_002019 |
hypothetical protein | Anti-sigma factor antagonist. Pfam: STAS (PF01740.27), STAS_2 (PF13466.13). | STAS STAS_2 |
Resolved |
| aao Rv1905c |
mtbc0_002020 |
D-amino acid oxidase | FAD-dependent oxidoreductase. Pfam: DAO (PF01266.31), FAD_binding_2 (PF00890.31). | DAO FAD_binding_2 |
Resolved |
| Rv1906c Rv1906c |
mtbc0_002021 |
hypothetical protein | Contains Rv1352 (PF27111.1) domain(s); putative function inferred from the domain architecture. | Rv1352 |
Family assigned |
| Rv1907c Rv1907c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF4262. Function unknown. Foldseek best (non-significant) hit: 4q3o-assembly4_H Crystal structure of MGS-MT1, an alpha/beta hydrolase (prob 0.04, TM 0.35). | DUF4262 |
Still unknown |
| katG Rv1908c |
mtbc0_002023 |
catalase-peroxidase | Catalase/peroxidase HPI. Pfam: peroxidase (PF00141.29). | peroxidase |
Resolved |
| furA Rv1909c |
mtbc0_002024 |
ferric uptake regulation protein FurA | Fur family transcriptional regulator. Pfam: FUR (PF01475.26). | FUR |
Family assigned |
| Rv1910c Rv1910c |
mtbc0_002025 |
hypothetical protein | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |