Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| PE_PGRS37 Rv2126c |
- |
PE-PGRS family protein PE_PGRS37 | PE-PGRS family protein PE_PGRS37. | Family assigned | |
| ansP1 Rv2127 |
- |
L-asparagine permease | L-asparagine permease. Pfam: AA_permease (PF00324.28), AA_permease_2 (PF13520.13). | AA_permease AA_permease_2 |
Resolved |
| Rv2128 Rv2128 |
mtbc0_002261 |
transmembrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2129c Rv2129c |
mtbc0_002262 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| mshC Rv2130c |
mtbc0_002263 |
cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase | Cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase. Pfam: tRNA-synt_1e (PF01406.26). | tRNA-synt_1e |
Resolved |
| cysQ Rv2131c |
mtbc0_002264 |
3'(2'),5'-bisphosphate nucleotidase CysQ | 3'(2')%2C5'-bisphosphate nucleotidase CysQ. Pfam: Inositol_P (PF00459.31). | Inositol_P |
Resolved |
| Rv2132 Rv2132 |
mtbc0_002265 |
hypothetical protein | Ribbon-helix-helix protein%2C CopG family. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Family assigned |
| Rv2133c Rv2133c |
mtbc0_002266 |
hypothetical protein | SCO1664 family protein. | Family assigned | |
| Rv2134c Rv2134c |
- |
hypothetical protein | Conserved hypothetical; function unknown. Structure-based hint rejected: weak fold hit (DUF3090); function unknown. | DUF3090 |
Still unknown |
| Rv2135c Rv2135c |
mtbc0_002268 |
hypothetical protein | Histidine phosphatase family protein. Pfam: His_Phos_1 (PF00300.28). | His_Phos_1 |
Family assigned |
| Rv2136c Rv2136c |
mtbc0_002269 |
undecaprenyl-diphosphatase | Undecaprenyl-diphosphate phosphatase. Pfam: BacA (PF02673.25). | BacA |
Resolved |
| Rv2137c Rv2137c |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6hhm-assembly1_A Crystal structure of the family S1_7 ulvan-specific s (prob 0.63, TM 0.66). | Still unknown | |
| lppL Rv2138 |
mtbc0_002271 |
lipoprotein LppL | PkwA-like protein (WD40-repeat / Ser-Thr-kinase-associated fold). RefSeq leaves it 'hypothetical protein'. | Family assigned | |
| pyrD Rv2139 |
mtbc0_002273 |
dihydroorotate dehydrogenase | Quinone-dependent dihydroorotate dehydrogenase. Pfam: DHO_dh (PF01180.28). | DHO_dh |
Resolved |
| TB18.6 Rv2140c |
mtbc0_002274 |
hypothetical protein | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |
| Rv2141c Rv2141c |
- |
hypothetical protein | Contains Peptidase_M28 (PF04389.23), Peptidase_M20 (PF01546.34), M20_dimer (PF07687.20) domain(s); putative function inferred from the domain architecture. | Peptidase_M28 Peptidase_M20 M20_dimer |
Family assigned |
| parD2 Rv2142A |
- |
antitoxin ParD2 | Antitoxin ParD2. | Resolved | |
| parE2 Rv2142c |
mtbc0_002277 |
toxin ParE2 | Type II toxin-antitoxin system RelE/ParE family toxin. Pfam: ParE_toxin (PF05016.22). | ParE_toxin |
Family assigned |
| Rv2143 Rv2143 |
mtbc0_002279 |
hypothetical protein | Phosphoribosyltransferase family protein. Pfam: Pribosyltran (PF00156.34). | Pribosyltran |
Family assigned |
| Rv2144c Rv2144c |
mtbc0_002280 |
transmembrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| wag31 Rv2145c |
mtbc0_002281 |
cell wall synthesis protein Wag31 | Cell wall synthesis protein Wag31. Pfam: DivIVA (PF05103.19). | DivIVA |
Resolved |
| Rv2146c Rv2146c |
mtbc0_002282 |
transmembrane protein | YggT family protein. Pfam: CCB3_YggT (PF02325.24). | CCB3_YggT |
Family assigned |
| Rv2147c Rv2147c |
- |
cell division protein SepF | Cell division protein SepF. Pfam: SepF (PF04472.18). | SepF |
Resolved |
| Rv2148c Rv2148c |
mtbc0_002284 |
hypothetical protein | YggS family pyridoxal phosphate-dependent enzyme. Pfam: Ala_racemase_N (PF01168.27). | Ala_racemase_N |
Family assigned |
| yfiH Rv2149c |
- |
laccase domain-containing protein | Laccase domain-containing protein. Pfam: Cu-oxidase_4 (PF02578.21). | Cu-oxidase_4 |
Family assigned |
| ftsZ Rv2150c |
mtbc0_002286 |
cell division protein FtsZ | Cell division protein FtsZ. Pfam: Tubulin (PF00091.32), FtsZ_C (PF12327.14). | Tubulin FtsZ_C |
Resolved |
| ftsQ Rv2151c |
mtbc0_002287 |
cell division protein FtsQ | Cell division protein FtsQ. Pfam: POTRA_1 (PF08478.16), FtsQ_DivIB_C (PF03799.21). | POTRA_1 FtsQ_DivIB_C |
Resolved |
| murC Rv2152c |
mtbc0_002288 |
UDP-N-acetylmuramate--alanine ligase | UDP-N-acetylmuramate--L-alanine ligase. Pfam: Mur_ligase (PF01225.31), Mur_ligase_M (PF08245.19), Mur_ligase_C (PF02875.27). | Mur_ligase Mur_ligase_M Mur_ligase_C |
Resolved |
| murG Rv2153c |
mtbc0_002289 |
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. Pfam: Glyco_transf_28 (PF03033.27), Glyco_tran_28_C (PF04101.23). | Glyco_transf_28 Glyco_tran_28_C |
Resolved |
| ftsW Rv2154c |
mtbc0_002290 |
lipid II flippase FtsW | Putative lipid II flippase FtsW. Pfam: FTSW_RODA_SPOVE (PF01098.25). | FTSW_RODA_SPOVE |
Family assigned |
| murD Rv2155c |
mtbc0_002291 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase. Pfam: Mur_ligase_M (PF08245.19), Mur_ligase_C (PF02875.27). | Mur_ligase_M Mur_ligase_C |
Resolved |
| murX Rv2156c |
mtbc0_002292 |
phospho-N-acetylmuramoyl-pentappeptidetransferase | Phospho-N-acetylmuramoyl-pentapeptide-transferase. Pfam: MraY_sig1 (PF10555.15), Glycos_transf_4 (PF00953.27). | MraY_sig1 Glycos_transf_4 |
Resolved |
| murF Rv2157c |
mtbc0_002293 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase. Pfam: Mur_ligase (PF01225.31), Mur_ligase_M (PF08245.19), Mur_ligase_C (PF02875.27). | Mur_ligase Mur_ligase_M Mur_ligase_C |
Resolved |
| murE Rv2158c |
mtbc0_002294 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase. Pfam: Mur_ligase (PF01225.31), Mur_ligase_M (PF08245.19), Mur_ligase_C (PF02875.27). | Mur_ligase Mur_ligase_M Mur_ligase_C |
Resolved |
| Rv2159c Rv2159c |
mtbc0_002295 |
hypothetical protein | Carboxymuconolactone decarboxylase family protein. Pfam: CMD (PF02627.26). | CMD |
Family assigned |
| Rv2160A Rv2160A |
|
Conserved hypothetical protein | PFAM regulatory protein TetR | TetR_N |
Family assigned |
| Rv2160c Rv2160c |
|
Conserved hypothetical protein | transcriptional regulator | TetR_C_13 |
Family assigned |
| Rv2161c Rv2161c |
mtbc0_002297 |
hypothetical protein | TIGR03619 family F420-dependent LLM class oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Family assigned |
| PE_PGRS38 Rv2162c |
- |
PE-PGRS family protein PE_PGRS38 | PE-PGRS family protein PE_PGRS38. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| pbpB Rv2163c |
mtbc0_002299 |
penicillin-binding membrane protein PbpB | D%2CD-transpeptidase PbpB. Pfam: PBP_dimer (PF03717.21), Transpeptidase (PF00905.28). | PBP_dimer Transpeptidase |
Resolved |
| Rv2164c Rv2164c |
mtbc0_002300 |
hypothetical protein | Cell-division / septum-associated membrane protein (eggNOG COG2919, 'essential cell division protein FtsB-like'; COG category D). RefSeq leaves it 'hypothetical protein'. Division-machinery role at orthology level. | Family assigned | |
| rsmH Rv2165c |
mtbc0_002301 |
rRNA small subunit methyltransferase H | 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH. Pfam: Methyltransf_5 (PF01795.26). | Methyltransf_5 |
Resolved |
| mraZ Rv2166c |
mtbc0_002302 |
transcriptional regulator MraZ | Division/cell wall cluster transcriptional repressor MraZ. Pfam: MraZ (PF02381.24). | MraZ |
Resolved |
| Rv2169c Rv2169c |
mtbc0_002303 |
transmembrane protein | Conserved hypothetical protein; DUF domain(s) DUF3040. Function unknown. | DUF3040 |
Still unknown |
| Rv2170 Rv2170 |
mtbc0_002304 |
GCN5-like N-acetyltransferase | N-acetyltransferase. Pfam: FR47 (PF08445.17), Acetyltransf_1 (PF00583.32), Acetyltransf_7 (PF13508.14). | FR47 Acetyltransf_1 Acetyltransf_7 |
Resolved |
| lppM Rv2171 |
mtbc0_002305 |
lipoprotein LppM | Lipoprotein LppM. Pfam: LppM (PF21946.2). | LppM |
Resolved |
| Rv2172c Rv2172c |
mtbc0_002306 |
hypothetical protein | Mycobacterial-type methylenetetrahydrofolate reductase. Pfam: MTHFR_2 (PF19345.6). | MTHFR_2 |
Resolved |
| idsA2 Rv2173 |
mtbc0_002307 |
geranylgeranyl pyrophosphate synthetase IdsA | Bifunctional (2E%2C6E)-farnesyl/geranyl diphosphate synthase. Pfam: polyprenyl_synt (PF00348.23). | polyprenyl_synt |
Resolved |
| mptA Rv2174 |
mtbc0_002308 |
alpha(1->6)-mannopyranosyltransferase A | Alpha-(1->6)-mannopyranosyltransferase A. Pfam: MptA_B_family (PF26314.1), MptA_C (PF27552.1). | MptA_B_family MptA_C |
Resolved |
| Rv2175c Rv2175c |
- |
DNA-binding protein | DNA-binding protein. Pfam: Rv2175c_wHTH (PF21531.4), Rv2175c_C (PF18367.7). | Rv2175c_wHTH Rv2175c_C |
Family assigned |