Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv0744c Rv0744c |
mtbc0_000789 |
transcriptional regulator | Helix-turn-helix domain-containing protein. Pfam: HTH_17 (PF12728.14). | HTH_17 |
Family assigned |
| Rv0745 Rv0745 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| PE_PGRS9 Rv0746 |
- |
PE-PGRS family protein PE_PGRS9 | PE-PGRS family protein PE_PGRS9. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| PE_PGRS10 Rv0747 |
- |
PE-PGRS family protein PE_PGRS10 | PE-PGRS family protein PE_PGRS10. Pfam: PE (PF00934.26). | PE |
Family assigned |
| vapB31 Rv0748 |
mtbc0_000295 |
antitoxin VapB31 | Ribbon-helix-helix protein%2C CopG family. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Family assigned |
| vapC31 Rv0749 |
mtbc0_000795 |
ribonuclease VapC31 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv0749A Rv0749A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0750 Rv0750 |
mtbc0_000797 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF7956. Function unknown. | DUF7956 |
Still unknown |
| mmsB Rv0751c |
mtbc0_000798 |
3-hydroxyisobutyrate dehydrogenase | 3-hydroxyisobutyrate dehydrogenase. Pfam: NAD_binding_2 (PF03446.22), F420_oxidored (PF03807.24), 2-Hacid_dh_C (PF02826.26), NAD_binding_11 (PF14833.12). | NAD_binding_2 F420_oxidored 2-Hacid_dh_C NAD_binding_11 |
Resolved |
| fadE9 Rv0752c |
mtbc0_000799 |
acyl-CoA dehydrogenase FadE9 | Acyl-CoA dehydrogenase family protein. Pfam: Acyl-CoA_dh_N (PF02771.22), Acyl-CoA_dh_M (PF02770.25), Acyl-CoA_dh_1 (PF00441.30), Acyl-CoA_dh_2 (PF08028.17), ACOX_C_alpha1 (PF22924.2). | Acyl-CoA_dh_N Acyl-CoA_dh_M Acyl-CoA_dh_1 Acyl-CoA_dh_2 ACOX_C_alpha1 |
Family assigned |
| mmsA Rv0753c |
mtbc0_000800 |
methylmalonate-semialdehyde dehydrogenase | CoA-acylating methylmalonate-semialdehyde dehydrogenase. Pfam: Aldedh (PF00171.28), LuxC (PF05893.20). | Aldedh LuxC |
Resolved |
| PE_PGRS11 Rv0754 |
- |
PE-PGRS family protein PE_PGRS11 | PE-PGRS family protein PE_PGRS11. Pfam: PE (PF00934.26), PGRS (PF21526.3), His_Phos_1 (PF00300.28). | PE PGRS His_Phos_1 |
Family assigned |
| PPE12 Rv0755c |
- |
PPE family protein PPE12 | PPE family protein PPE12. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| Rv0756c Rv0756c |
mtbc0_000805 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| phoP Rv0757 |
mtbc0_000806 |
two component system response transcriptional positive regulator PhoP | Two-component system response regulator PhoP. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| phoR Rv0758 |
mtbc0_000807 |
two component system response sensor kinase PhoR | Sensory box histidine kinase PhoR. Pfam: HAMP (PF00672.31), HisKA (PF00512.32), HATPase_c (PF02518.32). | HAMP HisKA HATPase_c |
Resolved |
| Rv0759c Rv0759c |
- |
hypothetical protein | Contains HIT (PF01230.30) domain(s); putative function inferred from the domain architecture. | HIT |
Family assigned |
| Rv0760c Rv0760c |
mtbc0_000809 |
hypothetical protein | Ketosteroid isomerase family protein. Pfam: NTF2 (PF02136.27), SnoaL_2 (PF12680.14). | NTF2 SnoaL_2 |
Family assigned |
| adhB Rv0761c |
- |
alcohol dehydrogenase B | Alcohol dehydrogenase B. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33). | ADH_N ADH_zinc_N |
Resolved |
| Rv0762c Rv0762c |
mtbc0_000811 |
hypothetical protein | Nuclear transport factor 2 family protein. | Family assigned | |
| Rv0763c Rv0763c |
mtbc0_000812 |
ferredoxin | Ferredoxin. Pfam: Fer4_19 (PF06902.17), Fer4_15 (PF13459.12), Fer4_13 (PF13370.12). | Fer4_19 Fer4_15 Fer4_13 |
Resolved |
| cyp51 Rv0764c |
mtbc0_000813 |
lanosterol 14-alpha demethylase | Lanosterol 14-alpha demethylase. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv0765c Rv0765c |
mtbc0_000814 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| cyp123 Rv0766c |
mtbc0_000815 |
cytochrome P450 Cyp123 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv0767c Rv0767c |
mtbc0_000816 |
HTH-type transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30). | TetR_N |
Family assigned |
| aldA Rv0768 |
mtbc0_000817 |
aldehyde dehydrogenase AldA | Aldehyde dehydrogenase. Pfam: Aldedh (PF00171.28). | Aldedh |
Resolved |
| Rv0769 Rv0769 |
mtbc0_000818 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv0770 Rv0770 |
mtbc0_000819 |
oxidoreductase | NAD(P)-dependent oxidoreductase. Pfam: NAD_binding_2 (PF03446.22), NAD_binding_11 (PF14833.12). | NAD_binding_2 NAD_binding_11 |
Resolved |
| Rv0771 Rv0771 |
mtbc0_000820 |
4-carboxymuconolactone decarboxylase | Carboxymuconolactone decarboxylase family protein. Pfam: CMD (PF02627.26). | CMD |
Family assigned |
| purD Rv0772 |
mtbc0_000821 |
phosphoribosylamine--glycine ligase | Phosphoribosylamine--glycine ligase. Pfam: GARS_N (PF02844.22), GARS_A (PF01071.25), GARS_C (PF02843.23). | GARS_N GARS_A GARS_C |
Resolved |
| ggtA Rv0773c |
- |
bifunctional cephalosporin acylase/gamma-glutamyltranspeptidase | Bifunctional cephalosporin acylase/gamma-glutamyltranspeptidase. Pfam: G_glu_transpept (PF01019.28). | G_glu_transpept |
Resolved |
| Rv0774c Rv0774c |
mtbc0_000823 |
hypothetical protein | Iron-stress inducible esterase. Pfam: Esterase (PF00756.27). | Esterase |
Resolved |
| Rv0775 Rv0775 |
mtbc0_000824 |
hypothetical protein | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_31 (PF17940.7). | TetR_N TetR_C_31 |
Family assigned |
| Rv0776c Rv0776c |
mtbc0_000825 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF429. Function unknown. Foldseek best (non-significant) hit: 4pht-assembly1_X ATPase GspE in complex with the cytoplasmic domain of (prob 0.60, TM 0.40). | DUF429 |
Still unknown |
| purB Rv0777 |
mtbc0_000826 |
adenylosuccinate lyase PurB | Adenylosuccinate lyase. Pfam: Lyase_1 (PF00206.26), ADSL_C (PF10397.15). | Lyase_1 ADSL_C |
Resolved |
| cyp126 Rv0778 |
mtbc0_000827 |
cytochrome P450 Cyp126 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv0779c Rv0779c |
mtbc0_000828 |
transmembrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| purC Rv0780 |
mtbc0_000829 |
phosphoribosylaminoimidazole-succinocarboxamide synthase | Phosphoribosylaminoimidazolesuccinocarboxamide synthase. Pfam: SAICAR_synt (PF01259.25). | SAICAR_synt |
Resolved |
| emrB Rv0783c |
mtbc0_000833 |
multidrug resistance protein EmrB | MFS transporter. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| Rv0784 Rv0784 |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2334. Function unknown. Foldseek best (non-significant) hit: 3cqh-assembly1_A Crystal Structure of L-xylulose-5-phosphate 3-epimera (prob 0.21, TM 0.37). | DUF2334 |
Still unknown |
| Rv0785 Rv0785 |
mtbc0_000835 |
KsdD-like steroid dehydrogenase | FAD-binding dehydrogenase. Pfam: FAD_binding_3 (PF01494.26), FAD_binding_2 (PF00890.31), NAD_binding_8 (PF13450.13). | FAD_binding_3 FAD_binding_2 NAD_binding_8 |
Resolved |
| Rv0786c Rv0786c |
mtbc0_000836 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B_3 (PF13483.13), Lactamase_B (PF00753.34), Lactamase_B_2 (PF12706.14). | Lactamase_B_3 Lactamase_B Lactamase_B_2 |
Resolved |
| Rv0787 Rv0787 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 4tmd-assembly1_A X-ray structure of Putative uncharacterized protein ( (prob 0.66, TM 0.36). | Still unknown | |
| Rv0787A Rv0787A |
- |
hypothetical protein | Contains PurS (PF02700.20) domain(s); putative function inferred from the domain architecture. | PurS |
Family assigned |
| purQ Rv0788 |
mtbc0_000839 |
phosphoribosylformylglycinamidine synthase | Phosphoribosylformylglycinamidine synthase subunit PurQ. Pfam: GATase_5 (PF13507.13), GATase (PF00117.35), GATase_3 (PF07685.21), DJ-1_PfpI (PF01965.31). | GATase_5 GATase GATase_3 DJ-1_PfpI |
Family assigned |
| Rv0789c Rv0789c |
- |
hypothetical protein | YbjN-like fold (putative sensor / regulatory protein). RefSeq leaves it 'hypothetical protein'. The AlphaFold model superposes on YbjN, a putative transcription regulator (PDB 6vu7; Foldseek prob 1.0, E 1e-5, TM 0.80). Fold-level assignment; the regulatory role and partners are not established. | Family assigned | |
| Rv0790c Rv0790c |
mtbc0_000841 |
hypothetical protein | Transglutaminase-like domain-containing protein. Pfam: Transglut_core (PF01841.26). | Transglut_core |
Family assigned |
| Rv0791c Rv0791c |
mtbc0_000842 |
hypothetical protein | LLM class flavin-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv0792c Rv0792c |
mtbc0_000843 |
transcriptional regulator | GntR family transcriptional regulator. Pfam: GntR (PF00392.28), UTRA (PF07702.19). | GntR UTRA |
Family assigned |
| Rv0793 Rv0793 |
mtbc0_000844 |
monooxygenase | Putative quinol monooxygenase. Pfam: ABM (PF03992.23). | ABM |
Family assigned |