Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2559c Rv2559c |
mtbc0_002727 |
hypothetical protein | Replication-associated recombination protein A. Pfam: RuvB_N (PF05496.19), Sigma54_activ_2 (PF14532.13), AAA (PF00004.36), AAA_5 (PF07728.21), AAA_assoc_2 (PF16193.12), MgsA_C (PF12002.14). | RuvB_N Sigma54_activ_2 AAA AAA_5 AAA_assoc_2 MgsA_C |
Resolved |
| Rv2560 Rv2560 |
mtbc0_002728 |
hypothetical protein | Membrane protein (33 kDa) localised to the mycobacterial membrane (immuno-EM); its high-activity binding peptides bind alveolar epithelial (A549) and monocyte (U937) cells and inhibit host-cell invasion, implicating it in adhesion/invasion of monocytes and epithelial cells. Molecular function unfixed. | Family assigned | |
| Rv2561 Rv2561 |
|
Conserved hypothetical protein | Pfam Adenylate and Guanylate cyclase catalytic domain | Family assigned | |
| Rv2562 Rv2562 |
|
Conserved hypothetical protein | Protein of unknown function (DUF2652) | Family assigned | |
| Rv2563 Rv2563 |
mtbc0_002730 |
glutamine ABC transporter permease | ABC transporter permease. Pfam: MacB_PCD (PF12704.15), FtsX (PF02687.28). | MacB_PCD FtsX |
Family assigned |
| glnQ Rv2564 |
mtbc0_002731 |
glutamine ABC transporter ATP-binding protein | ATP-binding cassette domain-containing protein. Pfam: ABC_tran (PF00005.34), cNMP_binding (PF00027.36). | ABC_tran cNMP_binding |
Family assigned |
| Rv2565 Rv2565 |
mtbc0_002732 |
NTE family protein | Patatin-like phospholipase family protein. Pfam: cNMP_binding (PF00027.36), Patatin (PF01734.28). | cNMP_binding Patatin |
Family assigned |
| Rv2566 Rv2566 |
- |
hypothetical protein | Contains Bact_transglu_N (PF08379.16), Transglut_core (PF01841.26), DUF2126 (PF09899.15) domain(s); putative function inferred from the domain architecture. | Bact_transglu_N Transglut_core DUF2126 |
Family assigned |
| Rv2567 Rv2567 |
mtbc0_002734 |
hypothetical protein | Circularly permuted type 2 ATP-grasp protein. Pfam: CP_ATPgrasp_1 (PF04174.19), CP_ATPgrasp_2 (PF14403.12), Alpha-E (PF04168.18). | CP_ATPgrasp_1 CP_ATPgrasp_2 Alpha-E |
Resolved |
| Rv2568c Rv2568c |
mtbc0_002735 |
hypothetical protein | Putative zinc-binding metallopeptidase. Pfam: Zn_ribbon_DZR_6 (PF10005.15), Peptidase_Mx (PF15887.12). | Zn_ribbon_DZR_6 Peptidase_Mx |
Family assigned |
| Rv2569c Rv2569c |
mtbc0_002736 |
hypothetical protein | Transglutaminase family protein. Pfam: Bact_transglu_N (PF08379.16), Transglut_core (PF01841.26). | Bact_transglu_N Transglut_core |
Family assigned |
| Rv2570 Rv2570 |
mtbc0_002737 |
hypothetical protein | MmcQ/YjbR family DNA-binding protein. Pfam: YjbR (PF04237.19). | YjbR |
Family assigned |
| Rv2571c Rv2571c |
mtbc0_002738 |
transmembrane protein | Aromatic acid exporter family protein. Pfam: FUSC_2 (PF13515.13). | FUSC_2 |
Family assigned |
| aspS Rv2572c |
mtbc0_002739 |
aspartate--tRNA ligase | Aspartate--tRNA ligase. Pfam: tRNA_anti-codon (PF01336.32), tRNA-synt_2 (PF00152.26), GAD (PF02938.20). | tRNA_anti-codon tRNA-synt_2 GAD |
Resolved |
| Rv2573 Rv2573 |
- |
2-dehydropantoate 2-reductase | 2-dehydropantoate 2-reductase. Pfam: ApbA (PF02558.23), ApbA_C (PF08546.18). | ApbA ApbA_C |
Resolved |
| Rv2574 Rv2574 |
mtbc0_002741 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv2575 Rv2575 |
mtbc0_002742 |
membrane protein | Neutral zinc metallopeptidase. Pfam: Zn_peptidase (PF04228.20). | Zn_peptidase |
Resolved |
| Rv2576c Rv2576c |
mtbc0_002743 |
membrane protein | Contains Rv2576c_beta (PF27168.1) domain(s); putative function inferred from the domain architecture. | Rv2576c_beta |
Family assigned |
| Rv2577 Rv2577 |
mtbc0_002744 |
hypothetical protein | Metallophosphoesterase family protein. Pfam: Pur_ac_phosph_N (PF16656.12), Metallophos (PF00149.34). | Pur_ac_phosph_N Metallophos |
Family assigned |
| Rv2578c Rv2578c |
mtbc0_002745 |
hypothetical protein | Rv2578c family radical SAM protein. Pfam: Radical_SAM (PF04055.28). | Radical_SAM |
Family assigned |
| dhaA Rv2579 |
- |
haloalkane dehalogenase | Haloalkane dehalogenase. Pfam: Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14). | Abhydrolase_1 Abhydrolase_6 |
Resolved |
| hisS Rv2580c |
mtbc0_002747 |
histidine--tRNA ligase | Histidine--tRNA ligase. Pfam: tRNA-synt_His (PF13393.12), tRNA-synt_2b (PF00587.31), HGTP_anticodon (PF03129.26). | tRNA-synt_His tRNA-synt_2b HGTP_anticodon |
Resolved |
| Rv2581c Rv2581c |
mtbc0_002748 |
glyoxalase II | MBL fold metallo-hydrolase. Pfam: Lactamase_B (PF00753.34). | Lactamase_B |
Resolved |
| ppiB Rv2582 |
- |
peptidyl-prolyl cis-trans isomerase B | Peptidyl-prolyl cis-trans isomerase B. Pfam: Pro_isomerase (PF00160.27). | Pro_isomerase |
Resolved |
| relA Rv2583c |
mtbc0_002750 |
bifunctional (p)ppGpp synthase/hydrolase RelA | RelA/SpoT family protein. Pfam: HD_4 (PF13328.13), HD (PF01966.29), RelA_SpoT (PF04607.24), TGS (PF02824.28), RelA_AH (PF19296.6), RelA_RIS (PF28438.1), ACT_4 (PF13291.13), ACT (PF01842.32). | HD_4 HD RelA_SpoT TGS RelA_AH RelA_RIS ACT_4 ACT |
Family assigned |
| apt Rv2584c |
mtbc0_002751 |
adenine phosphoribosyltransferase | Adenine phosphoribosyltransferase. Pfam: Pribosyltran (PF00156.34). | Pribosyltran |
Resolved |
| Rv2585c Rv2585c |
mtbc0_002752 |
lipoprotein | ABC transporter substrate-binding protein. Pfam: SBP_bac_5 (PF00496.28). | SBP_bac_5 |
Family assigned |
| secF Rv2586c |
mtbc0_002753 |
protein translocase subunit SecF | Protein translocase subunit SecF. Pfam: Sec_GG (PF07549.20), SecD_SecF_C (PF02355.23). | Sec_GG SecD_SecF_C |
Family assigned |
| secD Rv2587c |
mtbc0_002754 |
protein translocase subunit SecD | Protein translocase subunit SecD. Pfam: Sec_GG (PF07549.20), SecDF_P1_head (PF22599.3), SecD_SecF_C (PF02355.23). | Sec_GG SecDF_P1_head SecD_SecF_C |
Family assigned |
| yajC Rv2588c |
mtbc0_002755 |
membrane protein secretion factor YajC | Preprotein translocase subunit YajC. Pfam: YajC (PF02699.21). | YajC |
Family assigned |
| gabT Rv2589 |
mtbc0_002756 |
4-aminobutyrate aminotransferase | 4-aminobutyrate--2-oxoglutarate transaminase. Pfam: Aminotran_3 (PF00202.28). | Aminotran_3 |
Resolved |
| fadD9 Rv2590 |
mtbc0_002757 |
fatty-acid--CoA ligase FadD9 | Carboxylic acid reductase. Pfam: AMP-binding (PF00501.35), PP-binding (PF00550.32), Epimerase (PF01370.28), NAD_binding_4 (PF07993.19). | AMP-binding PP-binding Epimerase NAD_binding_4 |
Resolved |
| PE_PGRS44 Rv2591 |
- |
PE-PGRS family protein PE_PGRS44 | PE-PGRS family protein PE_PGRS44. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| ruvB Rv2592c |
mtbc0_002759 |
Holliday junction ATP-dependent DNA helicase RuvB | Holliday junction branch migration DNA helicase RuvB. Pfam: RuvB_N (PF05496.19), TIP49 (PF06068.20), AAA (PF00004.36), AAA_lid_4 (PF17864.8), WHD_RuvB (PF05491.20). | RuvB_N TIP49 AAA AAA_lid_4 WHD_RuvB |
Resolved |
| ruvA Rv2593c |
mtbc0_002760 |
Holliday junction ATP-dependent DNA helicase RuvA | Holliday junction branch migration protein RuvA. Pfam: RuvA_N (PF01330.28), HHH_5 (PF14520.13), RuvA_C (PF07499.20). | RuvA_N HHH_5 RuvA_C |
Resolved |
| ruvC Rv2594c |
mtbc0_002761 |
crossover junction endodeoxyribonuclease RuvC | Crossover junction endodeoxyribonuclease RuvC. Pfam: RuvC (PF02075.24). | RuvC |
Resolved |
| vapB40 Rv2595 |
mtbc0_002762 |
antitoxin VapB40 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein. Pfam: MazE_antitoxin (PF04014.24). | MazE_antitoxin |
Family assigned |
| vapC40 Rv2596 |
mtbc0_002763 |
ribonuclease VapC40 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv2597 Rv2597 |
mtbc0_002764 |
membrane protein | Conserved hypothetical protein; DUF domain(s) DUF4178. Function unknown. | DUF4178 |
Still unknown |
| Rv2598 Rv2598 |
mtbc0_002765 |
hypothetical protein | DUF2617 family protein. | DUF2617 |
Family assigned |
| Rv2599 Rv2599 |
mtbc0_002766 |
membrane protein | Membrane protein identified as a novel adhesin of M. tuberculosis: it binds the host extracellular-matrix proteins fibronectin, laminin and collagen (Kumar 2013). Also explored as a vaccine antigen. Molecular function = ECM-binding adhesin; further detail unfixed. | DUF4247 |
Family assigned |
| Rv2600 Rv2600 |
- |
integral membrane protein | Integral membrane protein. | DUF350 |
Family assigned |
| speE Rv2601 |
- |
spermidine synthase | Spermidine synthase. Pfam: Spermine_synth (PF01564.24). | Spermine_synth |
Resolved |
| vapB41 Rv2601A |
- |
antitoxin VapB41 | Antitoxin VapB41. | Resolved | |
| vapC41 Rv2602 |
mtbc0_002770 |
ribonuclease VapC41 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv2603c Rv2603c |
mtbc0_002771 |
transcriptional regulator | YebC/PmpR family DNA-binding transcriptional regulator. Pfam: TACO1_YebC_N (PF20772.3), Transcrip_reg (PF01709.27). | TACO1_YebC_N Transcrip_reg |
Family assigned |
| snoP Rv2604c |
mtbc0_002772 |
glutamine amidotransferase SnoP | Pyridoxal 5'-phosphate synthase glutaminase subunit PdxT. Pfam: SNO (PF01174.26), GATase_3 (PF07685.21). | SNO GATase_3 |
Family assigned |
| tesB2 Rv2605c |
mtbc0_002773 |
acyl-CoA thioesterase II | Acyl-CoA thioesterase II. Pfam: 4HBT_3 (PF13622.13), Acyl_CoA_thio (PF02551.22), 4HBT_3C (PF20789.4). | 4HBT_3 Acyl_CoA_thio 4HBT_3C |
Resolved |
| snzP Rv2606c |
mtbc0_002774 |
pyridoxine biosynthesis protein | Pyridoxal 5'-phosphate synthase lyase subunit PdxS. Pfam: SOR_SNZ (PF01680.24). | SOR_SNZ |
Family assigned |
| pdxH Rv2607 |
mtbc0_002775 |
pyridoxine/pyridoxamine 5'-phosphate oxidase | Pyridoxamine 5'-phosphate oxidase. Pfam: PNPOx_N (PF01243.28), PNP_phzG_C (PF10590.15). | PNPOx_N PNP_phzG_C |
Resolved |