Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| wbbL2 Rv1525 |
mtbc0_001632 |
rhamnosyl transferase WbbL | Glycosyltransferase family 2 protein. | Family assigned | |
| Rv1526c Rv1526c |
mtbc0_001633 |
glycosyltransferase | Glycosyltransferase. Pfam: Glyco_transf_28 (PF03033.27), EryCIII-like_C (PF06722.19). | Glyco_transf_28 EryCIII-like_C |
Resolved |
| pks5 Rv1527c |
mtbc0_001634 |
polyketide synthase | Sulfolipid-1 biosynthesis phthioceranic/hydroxyphthioceranic acid synthase. Pfam: ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), RhiE-like_linker (PF22336.3), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), PP-binding (PF00550.32). | ketoacyl-synt Thiolase_N Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C RhiE-like_linker Acyl_transf_1 PKS_DH_N PS-DH ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short PP-binding |
Resolved |
| papA4 Rv1528c |
mtbc0_001635 |
polyketide synthase associated protein PapA | PapA4, polyketide-synthase-ASSOCIATED protein (UniProt: 'probable conserved polyketide synthase associated protein PapA4') — an acyltransferase-type accessory protein of a PKS system, NOT a polyketide synthase. Its M. marinum ortholog MMAR_2343 acylates the fatty acyl chains of lipooligosaccharides (Sarkar et al. 2011); the M. tuberculosis protein itself is not characterised, and our structural layer returns no significant match (best prob 0.05). | Resolved | |
| fadD24 Rv1529 |
mtbc0_001636 |
fatty-acid--CoA ligase FadD24 | Fatty-acid--AMP ligase FAAL24/FadD24. Pfam: AMP-binding (PF00501.35), AMP-dom_DIP2-like (PF23024.2). | AMP-binding AMP-dom_DIP2-like |
Resolved |
| adh Rv1530 |
mtbc0_001637 |
alcohol dehydrogenase | Zinc-binding dehydrogenase. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33). | ADH_N ADH_zinc_N |
Resolved |
| Rv1531 Rv1531 |
mtbc0_001638 |
hypothetical protein | Carboxymuconolactone decarboxylase family protein. Pfam: CMD (PF02627.26). | CMD |
Family assigned |
| Rv1532c Rv1532c |
mtbc0_001639 |
hypothetical protein | PaaI family thioesterase. Pfam: DUF4442 (PF14539.13), 4HBT (PF03061.29). | DUF4442 4HBT |
Family assigned |
| Rv1533 Rv1533 |
mtbc0_001640 |
monooxygenase | Nitronate monooxygenase family protein. Pfam: NMO (PF03060.22), FMN_dh (PF01070.25). | NMO FMN_dh |
Family assigned |
| Rv1534 Rv1534 |
mtbc0_001641 |
transcriptional regulator | TetR family transcriptional regulator. Pfam: TetR_N (PF00440.30). | TetR_N |
Family assigned |
| Rv1535 Rv1535 |
mtbc0_001642 |
hypothetical protein | Rv1535 family protein. | Family assigned | |
| ileS Rv1536 |
mtbc0_001643 |
isoleucine--tRNA ligase | Isoleucine--tRNA ligase. Pfam: tRNA-synt_1 (PF00133.29), tRNA-synt_1g (PF09334.18), Anticodon_1 (PF08264.20), DUF5915 (PF19302.5). | tRNA-synt_1 tRNA-synt_1g Anticodon_1 DUF5915 |
Resolved |
| dinX Rv1537 |
mtbc0_001644 |
DNA polymerase IV | DNA polymerase IV. Pfam: IMS (PF00817.26), IMS_HHH (PF11798.15), IMS_HHH_1 (PF21999.3), IMS_C (PF11799.14). | IMS IMS_HHH IMS_HHH_1 IMS_C |
Resolved |
| ansA Rv1538c |
mtbc0_001645 |
L-aparaginase | Asparaginase. Pfam: Asparaginase (PF00710.26), Asparaginase_C (PF17763.7). | Asparaginase Asparaginase_C |
Resolved |
| lspA Rv1539 |
mtbc0_001646 |
lipoprotein signal peptidase | Signal peptidase II. Pfam: Peptidase_A8 (PF01252.24). | Peptidase_A8 |
Resolved |
| Rv1540 Rv1540 |
mtbc0_001647 |
RNA pseudouridine synthase | RNA pseudouridine synthase. Pfam: PseudoU_synth_2 (PF00849.28). | PseudoU_synth_2 |
Resolved |
| lprI Rv1541c |
mtbc0_001648 |
lipoprotein LprI | MliC family protein. Pfam: LprI (PF07007.18), MliC (PF09864.16). | LprI MliC |
Family assigned |
| glbN Rv1542c |
mtbc0_001649 |
hemoglobin GlbN | Group 1 truncated hemoglobin GlbN. Pfam: Bac_globin (PF01152.28). | Bac_globin |
Resolved |
| Rv1543 Rv1543 |
mtbc0_001650 |
oxidoreductase | SDR family NAD(P)-dependent oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv1544 Rv1544 |
mtbc0_001651 |
ketoacyl reductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv1545 Rv1545 |
mtbc0_001652 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3cht-assembly1_B Crystal Structure of Di-iron AurF with partially boun (prob 0.03, TM 0.23). | Still unknown | |
| Rv1546 Rv1546 |
mtbc0_001653 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| dnaE1 Rv1547 |
mtbc0_001654 |
DNA polymerase III subunit alpha | DNA polymerase III subunit alpha. Pfam: PHP (PF02811.27), DNA_pol3_alpha (PF07733.19), DNA_pol3_finger (PF17657.7), HHH_6 (PF14579.13), tRNA_anti-codon (PF01336.32). | PHP DNA_pol3_alpha DNA_pol3_finger HHH_6 tRNA_anti-codon |
Family assigned |
| PPE21 Rv1548c |
- |
PPE family protein PPE21 | PPE family protein PPE21. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| fadD11.1 Rv1549 |
|
Possible fatty-acid-CoA ligase FadD11.1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | Possible fatty-acid-CoA ligase FadD11.1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | AMP-binding |
Family assigned |
| fadD11 Rv1550 |
- |
fatty-acid--CoA ligase FadD11 | Fatty-acid--CoA ligase FadD11. Pfam: AMP-binding (PF00501.35), AMP-binding_C_3 (PF23562.3). | AMP-binding AMP-binding_C_3 |
Resolved |
| plsB1 Rv1551 |
mtbc0_001657 |
acyltransferase PlsB | Lysophospholipid acyltransferase. Pfam: Acyltransferase (PF01553.27), GPAT_C (PF19277.5). | Acyltransferase GPAT_C |
Resolved |
| frdA Rv1552 |
mtbc0_001659 |
fumarate reductase flavoprotein subunit | Fumarate reductase (quinol) flavoprotein subunit. Pfam: FAD_binding_2 (PF00890.31), Succ_DH_flav_C (PF02910.26). | FAD_binding_2 Succ_DH_flav_C |
Family assigned |
| frdB Rv1553 |
mtbc0_001660 |
fumarate reductase iron-sulfur subunit | Succinate dehydrogenase iron-sulfur subunit. Pfam: Fer2_3 (PF13085.12), Fer4_8 (PF13183.12), Fer4_10 (PF13237.12), Fer4 (PF00037.33), Fer4_7 (PF12838.13), Fer4_17 (PF13534.12). | Fer2_3 Fer4_8 Fer4_10 Fer4 Fer4_7 Fer4_17 |
Family assigned |
| frdC Rv1554 |
mtbc0_001661 |
fumarate reductase membrane anchor subunit | Fumarate reductase subunit C. Pfam: Fumarate_red_C (PF02300.23). | Fumarate_red_C |
Family assigned |
| frdD Rv1555 |
mtbc0_001662 |
fumarate reductase membrane anchor subunit | Fumarate reductase subunit FrdD. Pfam: Fumarate_red_D (PF02313.23). | Fumarate_red_D |
Family assigned |
| Rv1556 Rv1556 |
mtbc0_001663 |
HTH-type transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_11 (PF16859.11). | TetR_N TetR_C_11 |
Family assigned |
| mmpL6 Rv1557 |
- |
transmembrane transport protein MmpL6 | Transmembrane transport protein MmpL6. Pfam: MMPL (PF03176.22). | MMPL |
Resolved |
| Rv1558 Rv1558 |
mtbc0_001666 |
hypothetical protein | F420H(2)-dependent quinone reductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Resolved |
| ilvA Rv1559 |
mtbc0_001667 |
threonine dehydratase IlvA | Threonine ammonia-lyase. Pfam: PALP (PF00291.32), Thr_dehydrat_C (PF00585.25). | PALP Thr_dehydrat_C |
Resolved |
| vapB11 Rv1560 |
- |
antitoxin VapB11 | Antitoxin VapB11. Pfam: VapB_antitoxin (PF09957.16). | VapB_antitoxin |
Resolved |
| vapC11 Rv1561 |
mtbc0_001669 |
ribonuclease VapC11 | Type II toxin-antitoxin system toxin ribonuclease VapC11. Pfam: PIN (PF01850.28). | PIN |
Resolved |
| treZ Rv1562c |
- |
malto-oligosyltrehalose trehalohydrolase | Malto-oligosyltrehalose trehalohydrolase. Pfam: Alpha-amylase (PF00128.32), DUF3459 (PF11941.15). | Alpha-amylase DUF3459 |
Resolved |
| treY Rv1563c |
- |
maltooligosyl trehalose synthase | Maltooligosyl trehalose synthase. Pfam: Alpha-amylase (PF00128.32). | Alpha-amylase |
Resolved |
| treX Rv1564c |
- |
maltooligosyl trehalose synthase | Maltooligosyl trehalose synthase. Pfam: CBM_48 (PF02922.25), Alpha-amylase (PF00128.32), Isoamylase_C (PF21331.5). | CBM_48 Alpha-amylase Isoamylase_C |
Resolved |
| Rv1565c Rv1565c |
mtbc0_001673 |
acyltransferase | Acyltransferase family protein. Pfam: Acyl_transf_3 (PF01757.29), SGNH (PF19040.7). | Acyl_transf_3 SGNH |
Family assigned |
| ripD Rv1566c |
mtbc0_001674 |
hypothetical protein | NlpC/P60 family peptidoglycan-binding protein RipD. Pfam: NLPC_P60 (PF00877.26). | NLPC_P60 |
Family assigned |
| Rv1567c Rv1567c |
- |
membrane protein | Membrane protein. | Family assigned | |
| bioA Rv1568 |
mtbc0_001676 |
adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA | Adenosylmethionine--8-amino-7-oxononanoate transaminase. Pfam: Aminotran_3 (PF00202.28). | Aminotran_3 |
Resolved |
| bioF1 Rv1569 |
- |
8-amino-7-oxononanoate synthase | 8-amino-7-oxononanoate synthase. Pfam: Aminotran_1_2 (PF00155.28), Aminotran_5 (PF00266.26), DegT_DnrJ_EryC1 (PF01041.24). | Aminotran_1_2 Aminotran_5 DegT_DnrJ_EryC1 |
Resolved |
| bioD Rv1570 |
mtbc0_001678 |
ATP-dependent dethiobiotin synthetase BioD | Dethiobiotin synthase. Pfam: AAA_26 (PF13500.13), CbiA (PF01656.30). | AAA_26 CbiA |
Resolved |
| Rv1571 Rv1571 |
mtbc0_001679 |
hypothetical protein | 2'-5' RNA ligase family protein. Pfam: 2_5_RNA_ligase2 (PF13563.13). | 2_5_RNA_ligase2 |
Family assigned |
| Rv1572c Rv1572c |
|
Conserved hypothetical protein | — | Still unknown | |
| Rv1573 Rv1573 |
mtbc0_001680 |
phage protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1574 Rv1574 |
- |
phage protein | Phage protein. | Resolved |