Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv0898c Rv0898c |
mtbc0_000952 |
hypothetical protein | DUF2630 family protein. | DUF2630 |
Family assigned |
| arfA Rv0899 |
mtbc0_000953 |
peptidoglycan-binding protein ArfA | Peptidoglycan-binding protein ArfA. Pfam: BON_like (PF21923.2), BON (PF04972.23), OmpA (PF00691.26). | BON_like BON OmpA |
Family assigned |
| arfB Rv0900 |
mtbc0_000954 |
membrane protein | Small membrane protein that post-transcriptionally regulates expression of the major outer-membrane porin OmpATb. RefSeq leaves it 'membrane protein'. Rv0900 lies in an operon with ompATb (Rv0899) and Rv0901; mutations in Rv0900/Rv0901 strongly alter OmpATb expression, demonstrating a regulatory role (Veyron-Churlet 2011). | Family assigned | |
| arfC Rv0901 |
mtbc0_000955 |
membrane protein | Contains ArfC (PF27542.1) domain(s); putative function inferred from the domain architecture. | ArfC |
Family assigned |
| prrB Rv0902c |
mtbc0_000956 |
two component sensor histidine kinase PrrB | Two-component system sensor histidine kinase PrrB. Pfam: HAMP (PF00672.31), HisKA (PF00512.32), HATPase_c (PF02518.32). | HAMP HisKA HATPase_c |
Resolved |
| prrA Rv0903c |
mtbc0_000957 |
two component transcriptional regulator PrrA | Two-component system response regulator PrrA. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| accD3 Rv0904c |
mtbc0_000958 |
acetyl-CoAcarboxylase carboxyl transferase subunit beta | Carboxyl transferase domain-containing protein. Pfam: Carboxyl_trans (PF01039.28), ACCA (PF03255.20). | Carboxyl_trans ACCA |
Family assigned |
| echA6 Rv0905 |
mtbc0_000959 |
enoyl-CoA hydratase EchA6 | Enoyl-CoA hydratase. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Resolved |
| Rv0906 Rv0906 |
mtbc0_000960 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B_3 (PF13483.13), Lactamase_B_2 (PF12706.14). | Lactamase_B_3 Lactamase_B_2 |
Resolved |
| Rv0907 Rv0907 |
- |
hypothetical protein | Contains Beta-lactamase (PF00144.30), DUF3471 (PF11954.14) domain(s); putative function inferred from the domain architecture. | Beta-lactamase DUF3471 |
Family assigned |
| ctpE Rv0908 |
mtbc0_000962 |
metal cation transporter ATPase E | Cation-translocating P-type ATPase. Pfam: E1-E2_ATPase (PF00122.26), Hydrolase (PF00702.33), Hydrolase_3 (PF08282.19). | E1-E2_ATPase Hydrolase Hydrolase_3 |
Resolved |
| Rv0909 Rv0909 |
mtbc0_000964 |
antitoxin | Antitoxin. Pfam: MT0933_antitox (PF14013.12). | MT0933_antitox |
Resolved |
| Rv0910 Rv0910 |
mtbc0_000965 |
toxin | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv0911 Rv0911 |
mtbc0_000966 |
hypothetical protein | VOC family protein. Pfam: Ble-like_N (PF22677.3), Glyoxalase (PF00903.32), Glyoxalase_6 (PF18029.8). | Ble-like_N Glyoxalase Glyoxalase_6 |
Family assigned |
| Rv0912 Rv0912 |
mtbc0_000967 |
transmembrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0913c Rv0913c |
mtbc0_000969 |
dioxygenase | Carotenoid oxygenase family protein. Pfam: RPE65 (PF03055.22). | RPE65 |
Family assigned |
| Rv0914c Rv0914c |
mtbc0_000970 |
lipid carrier protein or keto acyl-CoA thiolase | Acetyl-CoA acetyltransferase. Pfam: Thiolase_N (PF00108.30), Thiolase_C_1 (PF22691.3), Thiolase_C (PF02803.25). | Thiolase_N Thiolase_C_1 Thiolase_C |
Resolved |
| PPE14 Rv0915c |
- |
PPE family protein PPE14 | PPE family protein PPE14. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| PE7 Rv0916c |
- |
PE family protein PE7 | PE family protein PE7. Pfam: PE (PF00934.26). | PE |
Family assigned |
| betP Rv0917 |
mtbc0_000973 |
glycine betaine transport integral membrane protein BetP | BCCT family transporter. Pfam: BCCT (PF02028.25). | BCCT |
Family assigned |
| Rv0918 Rv0918 |
mtbc0_000975 |
hypothetical protein | DUF1778 domain-containing protein. Pfam: TacA1 (PF08681.19). | TacA1 |
Family assigned |
| Rv0919 Rv0919 |
mtbc0_000976 |
GCN5-like N-acetyltransferase | GNAT family N-acetyltransferase. Pfam: Acetyltransf_10 (PF13673.14), Acetyltransf_1 (PF00583.32), Acetyltransf_7 (PF13508.14). | Acetyltransf_10 Acetyltransf_1 Acetyltransf_7 |
Family assigned |
| Rv0920c Rv0920c |
mtbc0_000978 |
transposase | IS256-like element IS1554 family transposase. Pfam: Transposase_mut (PF00872.25). | Transposase_mut |
Family assigned |
| Rv0921 Rv0921 |
mtbc0_000979 |
resolvase | IS607-like element IS1535 family transposase. Pfam: Resolvase (PF00239.27). | Resolvase |
Family assigned |
| tnpB Rv0922 |
mtbc0_000980 |
transposase | IS607 family element RNA-guided endonuclease TnpB. Pfam: OrfB_IS605 (PF01385.26), Cas12f1-like_TNB (PF07282.19). | OrfB_IS605 Cas12f1-like_TNB |
Family assigned |
| Rv0923c Rv0923c |
mtbc0_000981 |
hypothetical protein | Poly-gamma-glutamate hydrolase family protein. Pfam: GGACT (PF06094.18), AIG2_2 (PF13772.12), Gamma_PGA_hydro (PF05908.17). | GGACT AIG2_2 Gamma_PGA_hydro |
Family assigned |
| mntH Rv0924c |
- |
divalent metal cation transporter MntH | Divalent metal cation transporter MntH. Pfam: Nramp (PF01566.26). | Nramp |
Resolved |
| Rv0925c Rv0925c |
mtbc0_000983 |
hypothetical protein | Flavodoxin family protein. Pfam: FMN_red (PF03358.21). | FMN_red |
Family assigned |
| Rv0926c Rv0926c |
mtbc0_000984 |
hypothetical protein | Diacylglycerol kinase. Pfam: DAP_DH_C (PF19328.5). | DAP_DH_C |
Resolved |
| Rv0927c Rv0927c |
mtbc0_000985 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| pstS3 Rv0928 |
- |
phosphate ABC transporter substrate-binding lipoprotein PstS | Phosphate ABC transporter substrate-binding lipoprotein PstS. Pfam: PBP_like_2 (PF12849.13), SBP_bac_1 (PF01547.31). | PBP_like_2 SBP_bac_1 |
Family assigned |
| pstC2 Rv0929 |
mtbc0_000987 |
phosphate ABC transporter permease PstC | Phosphate ABC transporter permease subunit PstC. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| pstA1 Rv0930 |
- |
phosphate ABC transporter permease PstA | Phosphate ABC transporter permease PstA. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| pknD Rv0931c |
mtbc0_000989 |
serine/threonine-protein kinase PknD | Serine/threonine protein kinase PknD. Pfam: Pkinase (PF00069.32), PK_Tyr_Ser-Thr (PF07714.24), NHL (PF01436.28). | Pkinase PK_Tyr_Ser-Thr NHL |
Resolved |
| pstS2 Rv0932c |
- |
phosphate ABC transporter substrate-binding lipoprotein PstS | Phosphate ABC transporter substrate-binding lipoprotein PstS. Pfam: PBP_like_2 (PF12849.13), SBP_bac_1 (PF01547.31). | PBP_like_2 SBP_bac_1 |
Family assigned |
| pstB Rv0933 |
mtbc0_000991 |
phosphate ABC transporter ATP-binding protein PstB | Phosphate ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34), AAA_21 (PF13304.13). | ABC_tran AAA_21 |
Family assigned |
| pstS1 Rv0934 |
- |
phosphate ABC transporter substrate-binding lipoprotein PstS | Phosphate ABC transporter substrate-binding lipoprotein PstS. Pfam: PBP_like_2 (PF12849.13), SBP_bac_1 (PF01547.31). | PBP_like_2 SBP_bac_1 |
Family assigned |
| pstC1 Rv0935 |
- |
phosphate ABC transporter permease PstC | Phosphate ABC transporter permease PstC. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| pstA2 Rv0936 |
mtbc0_000994 |
phosphate ABC transporter permease PstA | Phosphate ABC transporter permease PstA. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| mku Rv0937c |
mtbc0_000995 |
non-homologous end joining protein Ku | Ku protein. Pfam: Ku (PF02735.23). | Ku |
Resolved |
| ligD Rv0938 |
mtbc0_000996 |
multifunctional non-homologous end joining DNA repair protein/ATP dependent DNA ligase LigD | ATP-dependent DNA ligase. Pfam: LigD_Prim-Pol (PF21686.4), DNA_primase_S (PF01896.26), LigD_N (PF13298.13), DNA_ligase_A_M (PF01068.27), DNA_ligase_A_C (PF04679.22). | LigD_Prim-Pol DNA_primase_S LigD_N DNA_ligase_A_M DNA_ligase_A_C |
Resolved |
| Rv0939 Rv0939 |
mtbc0_000997 |
bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase | Fumarylacetoacetate hydrolase family protein. Pfam: FAA_hydrolase (PF01557.24), Lactamase_B (PF00753.34). | FAA_hydrolase Lactamase_B |
Family assigned |
| Rv0940c Rv0940c |
mtbc0_000998 |
oxidoreductase | TIGR03619 family F420-dependent LLM class oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Family assigned |
| Rv0941c Rv0941c |
mtbc0_000999 |
hypothetical protein | STAS domain-containing protein. Pfam: STAS (PF01740.27). | STAS |
Family assigned |
| Rv0942 Rv0942 |
mtbc0_001000 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF8092. Function unknown. Foldseek best (non-significant) hit: 7va4-assembly1_D Telomeric tetranucleosome in open state (prob 0.06, TM 0.28). | DUF8092 |
Still unknown |
| Rv0943c Rv0943c |
mtbc0_001002 |
monooxygenase | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0944 Rv0944 |
- |
formamidopyrimidine-DNA glycosylase | Formamidopyrimidine-DNA glycosylase. Pfam: H2TH (PF06831.20), zf-FPG_IleRS (PF06827.21). | H2TH zf-FPG_IleRS |
Resolved |
| Rv0945 Rv0945 |
- |
oxidoreductase | Oxidoreductase. Pfam: SDR (PF23441.1), adh_short (PF00106.32), KR (PF08659.17), Epimerase (PF01370.28), adh_short_C2 (PF13561.13). | SDR adh_short KR Epimerase adh_short_C2 |
Resolved |
| pgi Rv0946c |
mtbc0_001009 |
glucose-6-phosphate isomerase | Glucose-6-phosphate isomerase. Pfam: PGI (PF00342.25). | PGI |
Resolved |
| Rv0948c Rv0948c |
mtbc0_001012 |
chorismate mutase | Chorismate mutase. Pfam: CM_2 (PF01817.27). | CM_2 |
Resolved |