Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| PPE33 Rv1809 |
- |
PPE family protein PPE33 | PPE family protein PPE33. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| Rv1810 Rv1810 |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF732. Function unknown. Foldseek best (non-significant) hit: 2jps-assembly1_A NAB2 N-terminal domain (prob 0.20, TM 0.52). | DUF732 |
Still unknown |
| mgtC Rv1811 |
mtbc0_001923 |
Mg2+ transport P-type ATPase MgtC | MgtC/SapB family protein. Pfam: MgtC (PF02308.22), MgtC_SapB_C (PF21770.4). | MgtC MgtC_SapB_C |
Family assigned |
| Rv1812c Rv1812c |
mtbc0_001924 |
dehydrogenase | NAD(P)/FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21). | Pyr_redox_2 |
Resolved |
| Rv1813c Rv1813c |
mtbc0_001925 |
hypothetical protein | DUF4189; structure solved (PDB 7NHZ, Rv1813c); secreted DUF4189-family protein. | DUF4189 |
Family assigned |
| erg3 Rv1814 |
- |
membrane-bound C-5 sterol desaturase | Membrane-bound C-5 sterol desaturase. Pfam: FA_hydroxylase (PF04116.20). | FA_hydroxylase |
Resolved |
| Rv1815 Rv1815 |
mtbc0_001927 |
hypothetical protein | Protease-like fold (L5 protease, PDB 5MRT); putative peptidase. | Family assigned | |
| Rv1816 Rv1816 |
- |
HTH-type transcriptional regulator | HTH-type transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_33 (PF13305.12). | TetR_N TetR_C_33 |
Family assigned |
| Rv1817 Rv1817 |
mtbc0_001931 |
flavoprotein | FAD-binding protein. Pfam: FAD_binding_2 (PF00890.31), DAO (PF01266.31), FAD_oxidored (PF12831.14). | FAD_binding_2 DAO FAD_oxidored |
Family assigned |
| PE_PGRS33 Rv1818c |
- |
PE-PGRS family protein PE_PGRS33 | PE-PGRS family protein PE_PGRS33. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| bacA Rv1819c |
mtbc0_001933 |
vitamin B12 transport ATP-binding protein BacA | Vitamin B12 ABC transporter ATP-binding protein BacA. Pfam: ABC_membrane_2 (PF06472.21), SbmA_BacA (PF05992.18), ABC_tran (PF00005.34). | ABC_membrane_2 SbmA_BacA ABC_tran |
Family assigned |
| ilvG Rv1820 |
mtbc0_001934 |
acetolactate synthase large subunit IlvG | Acetolactate synthase. Pfam: TPP_enzyme_N (PF02776.24), TPP_enzyme_M (PF00205.29), TPP_enzyme_C (PF02775.27). | TPP_enzyme_N TPP_enzyme_M TPP_enzyme_C |
Resolved |
| secA2 Rv1821 |
- |
accessory Sec system translocase SecA2 | Accessory Sec system translocase SecA2. Pfam: SecA_DEAD (PF07517.21), SecA_PP_bind (PF01043.27), P-loop_SecA (PF21090.4), SecA_SW (PF07516.19). | SecA_DEAD SecA_PP_bind P-loop_SecA SecA_SW |
Resolved |
| pgsA2 Rv1822 |
mtbc0_001936 |
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | CDP-alcohol phosphatidyltransferase family protein. Pfam: CDP-OH_P_transf (PF01066.27). | CDP-OH_P_transf |
Family assigned |
| Rv1823 Rv1823 |
mtbc0_001937 |
hypothetical protein | Small coiled-coil membrane protein, candidate divisome / cell-division-associated component (FtsB/FtsL-like); paralog of the uncharacterized Rv1825; coiled-coil fold limits confidence RefSeq leaves this locus uncharacterised. | DUF881 |
Family assigned |
| Rv1824 Rv1824 |
mtbc0_001938 |
hypothetical protein | Small basic family protein. | DUF1290 |
Family assigned |
| Rv1825 Rv1825 |
mtbc0_001939 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF881. Function unknown. Foldseek best (non-significant) hit: 3gmg-assembly1_B Crystal structure of an uncharacterized conserved pro (prob 1.00, TM 0.93). | DUF881 |
Still unknown |
| gcvH Rv1826 |
mtbc0_001940 |
glycine cleavage system protein H | Glycine cleavage system protein GcvH. Pfam: GCV_H (PF01597.26). | GCV_H |
Resolved |
| garA Rv1827 |
mtbc0_001941 |
glycogen accumulation regulator GarA | Glycogen accumulation regulator GarA. Pfam: Yop-YscD_cpl (PF16697.11), FHA (PF00498.32). | Yop-YscD_cpl FHA |
Resolved |
| Rv1828 Rv1828 |
mtbc0_001942 |
HTH-type transcriptional regulator | MerR family transcriptional regulator. Pfam: MerR (PF00376.30), MerR_1 (PF13411.13), HTH_Rv1828 (PF28507.1). | MerR MerR_1 HTH_Rv1828 |
Family assigned |
| Rv1829 Rv1829 |
- |
hypothetical protein | Contains BFN_dom (PF02577.20) domain(s); putative function inferred from the domain architecture. | BFN_dom |
Family assigned |
| Rv1830 Rv1830 |
- |
HTH-type transcriptional regulator | HTH-type transcriptional regulator. Pfam: MerR_1 (PF13411.13). | MerR_1 |
Family assigned |
| Rv1831 Rv1831 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| gcvB Rv1832 |
mtbc0_001945 |
glycine dehydrogenase | Aminomethyl-transferring glycine dehydrogenase. Pfam: GDC-P (PF02347.23), GcvP2_C (PF21478.4). | GDC-P GcvP2_C |
Resolved |
| Rv1833c Rv1833c |
mtbc0_001946 |
haloalkane dehalogenase | Haloalkane dehalogenase. Pfam: Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14), Hydrolase_4 (PF12146.16). | Abhydrolase_1 Abhydrolase_6 Hydrolase_4 |
Resolved |
| lipZ Rv1834 |
mtbc0_001947 |
hydrolase | Alpha/beta hydrolase. Pfam: Abhydrolase_1 (PF00561.27), Hydrolase_4 (PF12146.16), Abhydrolase_6 (PF12697.14). | Abhydrolase_1 Hydrolase_4 Abhydrolase_6 |
Family assigned |
| Rv1835c Rv1835c |
mtbc0_001948 |
serine esterase | CocE/NonD family hydrolase. Pfam: Peptidase_S15 (PF02129.25), PepX_C (PF08530.17). | Peptidase_S15 PepX_C |
Family assigned |
| Rv1836c Rv1836c |
mtbc0_001949 |
hypothetical protein | Substrate-binding domain-containing protein. Pfam: SBP_bac_11 (PF13531.12). | SBP_bac_11 |
Family assigned |
| glcB Rv1837c |
mtbc0_001950 |
malate synthase | Malate synthase G. Pfam: MS_N (PF20656.3), MSG_insertion (PF20658.3), MS_TIM-barrel (PF01274.29), MS_C (PF20659.3). | MS_N MSG_insertion MS_TIM-barrel MS_C |
Resolved |
| vapC13 Rv1838c |
mtbc0_001951 |
ribonuclease VapC13 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| vapB13 Rv1839c |
mtbc0_001952 |
antitoxin VapB13 | Antitoxin. | Resolved | |
| PE_PGRS34 Rv1840c |
- |
PE-PGRS family protein PE_PGRS34 | PE-PGRS family protein PE_PGRS34. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| Rv1841c Rv1841c |
mtbc0_001954 |
hypothetical protein | Hemolysin family protein. Pfam: CNNM (PF01595.26), CBS (PF00571.34). | CNNM CBS |
Family assigned |
| Rv1842c Rv1842c |
mtbc0_001955 |
hypothetical protein | Hemolysin family protein. Pfam: CNNM (PF01595.26), CBS (PF00571.34), CorC_HlyC (PF03471.23). | CNNM CBS CorC_HlyC |
Family assigned |
| guaB1 Rv1843c |
mtbc0_001956 |
inosine-5'-monophosphate dehydrogenase | GuaB1 family IMP dehydrogenase-related protein. Pfam: IMPDH (PF00478.32), CBS (PF00571.34). | IMPDH CBS |
Family assigned |
| gnd1 Rv1844c |
- |
6-phosphogluconate dehydrogenase | 6-phosphogluconate dehydrogenase. Pfam: NAD_binding_2 (PF03446.22), 6PGD (PF00393.25). | NAD_binding_2 6PGD |
Resolved |
| blaR Rv1845c |
mtbc0_001958 |
sensor-transducer protein BlaR | M56 family metallopeptidase. Pfam: Peptidase_M48 (PF01435.25). | Peptidase_M48 |
Family assigned |
| blaI Rv1846c |
mtbc0_001959 |
transcriptional repressor BlaI | Transcriptional repressor BlaI. Pfam: Penicillinase_R (PF03965.23). | Penicillinase_R |
Resolved |
| Rv1847 Rv1847 |
mtbc0_001960 |
esterase | PaaI family thioesterase. Pfam: DUF4442 (PF14539.13), 4HBT (PF03061.29). | DUF4442 4HBT |
Family assigned |
| ureA Rv1848 |
mtbc0_001961 |
urease subunit gamma | Urease subunit gamma. Pfam: Urease_gamma (PF00547.24). | Urease_gamma |
Family assigned |
| ureB Rv1849 |
mtbc0_001962 |
urease subunit beta | Urease subunit beta. Pfam: Urease_beta (PF00699.26). | Urease_beta |
Family assigned |
| ureC Rv1850 |
mtbc0_001963 |
urease subunit alpha | Urease subunit alpha. Pfam: Urease_alpha (PF00449.27), Amidohydro_1 (PF01979.27). | Urease_alpha Amidohydro_1 |
Family assigned |
| ureF Rv1851 |
mtbc0_001964 |
urease accessory protein UreF | Urease accessory protein UreF. Pfam: UreF (PF01730.22). | UreF |
Resolved |
| ureG Rv1852 |
mtbc0_001965 |
urease accessory protein UreG | Urease accessory protein UreG. Pfam: cobW (PF02492.26). | cobW |
Resolved |
| ureD Rv1853 |
- |
urease accessory protein UreD | Urease accessory protein UreD. Pfam: UreD (PF01774.23). | UreD |
Resolved |
| ndh Rv1854c |
mtbc0_001967 |
NADH dehydrogenase | NAD(P)/FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox (PF00070.34). | Pyr_redox_2 Pyr_redox |
Resolved |
| Rv1855c Rv1855c |
mtbc0_001968 |
oxidoreductase | LLM class F420-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv1856c Rv1856c |
mtbc0_001969 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| modA Rv1857 |
mtbc0_001970 |
molybdate ABC transporter substrate-binding lipoprotein ModA | Molybdate ABC transporter substrate-binding protein. Pfam: SBP_bac_11 (PF13531.12), SBP_bac_1 (PF01547.31). | SBP_bac_11 SBP_bac_1 |
Family assigned |
| modB Rv1858 |
mtbc0_001971 |
molybdenum ABC transporter permease ModB | ABC transporter permease. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |