Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| pyrB Rv1380 |
mtbc0_001481 |
aspartate carbamoyltransferase | Aspartate carbamoyltransferase catalytic subunit. Pfam: OTCace_N (PF02729.27), OTCace (PF00185.31). | OTCace_N OTCace |
Family assigned |
| pyrC Rv1381 |
mtbc0_001482 |
dihydroorotase | Dihydroorotase. Pfam: DHOase (PF12890.14), Amidohydro_1 (PF01979.27). | DHOase Amidohydro_1 |
Resolved |
| Rv1382 Rv1382 |
mtbc0_001483 |
hypothetical protein | Transporter. Pfam: bPH_11 (PF25362.2). | bPH_11 |
Resolved |
| carA Rv1383 |
mtbc0_001484 |
carbamoyl-phosphate synthase small subunit | Glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit. Pfam: CPSase_sm_chain (PF00988.29), GATase (PF00117.35), Peptidase_C26 (PF07722.20). | CPSase_sm_chain GATase Peptidase_C26 |
Family assigned |
| carB Rv1384 |
- |
carbamoyl-phosphate synthase large subunit | Carbamoyl-phosphate synthase large subunit. Pfam: CPSase_L_D2 (PF02786.23), CPSase_L_D3 (PF02787.26), CPSase_L_D1 (PF25596.2), Dala_Dala_lig_C (PF07478.19), ATP-grasp (PF02222.28), MGS (PF02142.28). | CPSase_L_D2 CPSase_L_D3 CPSase_L_D1 Dala_Dala_lig_C ATP-grasp MGS |
Family assigned |
| pyrF Rv1385 |
mtbc0_001486 |
orotidine 5'-phosphate decarboxylase | Orotidine-5'-phosphate decarboxylase. Pfam: OMPdecase (PF00215.31). | OMPdecase |
Resolved |
| PE15 Rv1386 |
- |
PE family protein PE15 | PE family protein PE15. Pfam: PE (PF00934.26). | PE |
Family assigned |
| PPE20 Rv1387 |
- |
PPE family protein PPE20 | PPE family protein PPE20. Pfam: PPE (PF00823.26), PPE-PPW (PF18878.6). | PPE PPE-PPW |
Family assigned |
| mihF Rv1388 |
- |
integration host factor MihF | Integration host factor MihF. Pfam: H2TH_5 (PF22525.2). | H2TH_5 |
Resolved |
| gmk Rv1389 |
mtbc0_001490 |
guanylate kinase | Guanylate kinase. Pfam: Guanylate_kin (PF00625.28). | Guanylate_kin |
Resolved |
| rpoZ Rv1390 |
mtbc0_001491 |
DNA-directed RNA polymerase subunit omega | DNA-directed RNA polymerase subunit omega. Pfam: RNA_pol_Rpb6 (PF01192.28). | RNA_pol_Rpb6 |
Family assigned |
| dfp Rv1391 |
mtbc0_001492 |
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC. Pfam: Flavoprotein (PF02441.25), DFP (PF04127.23). | Flavoprotein DFP |
Resolved |
| metK Rv1392 |
- |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase. Pfam: S-AdoMet_synt_N (PF00438.26), S-AdoMet_synt_M (PF02772.22), S-AdoMet_synt_C (PF02773.22). | S-AdoMet_synt_N S-AdoMet_synt_M S-AdoMet_synt_C |
Resolved |
| Rv1393c Rv1393c |
mtbc0_001494 |
monoxygenase | NAD(P)/FAD-dependent oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox_3 (PF13738.13), NAD_binding_8 (PF13450.13), FMO-like (PF00743.26). | Pyr_redox_2 Pyr_redox_3 NAD_binding_8 FMO-like |
Resolved |
| cyp132 Rv1394c |
- |
cytochrome P450 Cyp132 | Cytochrome P450 Cyp132. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv1395 Rv1395 |
- |
HTH-type transcriptional regulator | HTH-type transcriptional regulator. Pfam: Arabinose_bd (PF12625.13), HTH_18 (PF12833.14). | Arabinose_bd HTH_18 |
Family assigned |
| PE_PGRS25 Rv1396c |
- |
PE-PGRS family protein PE_PGRS25 | PE-PGRS family protein PE_PGRS25. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| vapC10 Rv1397c |
mtbc0_001498 |
ribonuclease VapC10 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| vapB10 Rv1398c |
mtbc0_001499 |
antitoxin VapB10 | CopG family transcriptional regulator. Pfam: RHH_5 (PF07878.18), RHH_1 (PF01402.28). | RHH_5 RHH_1 |
Family assigned |
| nlhH Rv1399c |
mtbc0_001500 |
carboxylesterase NlhH | Alpha/beta hydrolase. Pfam: BD-FAE (PF20434.6), COesterase (PF00135.35), Abhydrolase_3 (PF07859.20). | BD-FAE COesterase Abhydrolase_3 |
Family assigned |
| lipI Rv1400c |
mtbc0_001501 |
lipase | Alpha/beta hydrolase. Pfam: BD-FAE (PF20434.6), COesterase (PF00135.35), Abhydrolase_3 (PF07859.20). | BD-FAE COesterase Abhydrolase_3 |
Family assigned |
| Rv1401 Rv1401 |
- |
membrane protein | Membrane protein. Pfam: YhhN (PF07947.20). | YhhN |
Family assigned |
| priA Rv1402 |
- |
primosomal protein N' | Primosomal protein N'. Pfam: PriA_3primeBD (PF17764.7), PriA_C_2 (PF27106.1). | PriA_3primeBD PriA_C_2 |
Family assigned |
| Rv1403c Rv1403c |
mtbc0_001504 |
methyltransferase | Class I SAM-dependent methyltransferase. Pfam: Ubie_methyltran (PF01209.25), Methyltransf_31 (PF13847.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Ubie_methyltran Methyltransf_31 Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Resolved |
| Rv1404 Rv1404 |
mtbc0_001505 |
transcriptional regulator | MarR family transcriptional regulator. Pfam: MarR_2 (PF12802.14), MarR (PF01047.29). | MarR_2 MarR |
Family assigned |
| Rv1405c Rv1405c |
mtbc0_001506 |
methyltransferase | Virulence-associated methyltransferase. Pfam: Ubie_methyltran (PF01209.25), Methyltransf_31 (PF13847.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Ubie_methyltran Methyltransf_31 Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Resolved |
| fmt Rv1406 |
mtbc0_001507 |
methionyl-tRNA formyltransferase | Methionyl-tRNA formyltransferase. Pfam: Formyl_trans_N (PF00551.25), Formyl_trans_C (PF02911.24). | Formyl_trans_N Formyl_trans_C |
Resolved |
| fmu Rv1407 |
mtbc0_001508 |
16S rRNA m5C967 methyltransferase | 16S rRNA m5C967 methyltransferase. Pfam: NusB (PF01029.24), Methyltr_RsmB-F (PF01189.24). | NusB Methyltr_RsmB-F |
Resolved |
| rpe Rv1408 |
mtbc0_001509 |
ribulose-phosphate 3-epimerase | Ribulose-phosphate 3-epimerase. Pfam: Ribul_P_3_epim (PF00834.26). | Ribul_P_3_epim |
Resolved |
| ribG Rv1409 |
mtbc0_001510 |
bifunctional riboflavin biosynthesis diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase | Bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD. Pfam: dCMP_cyt_deam_1 (PF00383.30), MafB19-deam (PF14437.13), RibD_C (PF01872.23). | dCMP_cyt_deam_1 MafB19-deam RibD_C |
Resolved |
| Rv1410c Rv1410c |
mtbc0_001511 |
aminoglycosides/tetracycline-transport integral membrane protein | Aminoglycoside/tetracycline transporter. Pfam: MFS_1 (PF07690.22), TRI12 (PF06609.19), Sugar_tr (PF00083.31). | MFS_1 TRI12 Sugar_tr |
Resolved |
| lprG Rv1411c |
mtbc0_001512 |
lipoprotein LprG | Lipoarabinomannan carrier protein LprG. Pfam: LppX_LprAFG (PF07161.20). | LppX_LprAFG |
Resolved |
| ribC Rv1412 |
mtbc0_001513 |
riboflavin synthase | Riboflavin synthase. Pfam: Lum_binding (PF00677.24). | Lum_binding |
Resolved |
| Rv1413 Rv1413 |
- |
hypothetical protein | Contains Ala_racemase_N (PF01168.27) domain(s); putative function inferred from the domain architecture. | Ala_racemase_N |
Family assigned |
| Rv1414 Rv1414 |
- |
hypothetical protein | Contains D-ser_dehydrat (PF14031.14) domain(s); putative function inferred from the domain architecture. | D-ser_dehydrat |
Family assigned |
| ribA2 Rv1415 |
mtbc0_001515 |
bifunctional riboflavin biosynthesis GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase | Bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II. Pfam: DHBP_synthase (PF00926.25), GTP_cyclohydro2 (PF00925.26). | DHBP_synthase GTP_cyclohydro2 |
Resolved |
| ribH Rv1416 |
mtbc0_001516 |
6,7-dimethyl-8-ribityllumazine synthase | 6%2C7-dimethyl-8-ribityllumazine synthase. Pfam: DMRL_synthase (PF00885.25). | DMRL_synthase |
Resolved |
| Rv1417 Rv1417 |
mtbc0_001517 |
membrane protein | PH domain-containing protein. Pfam: bPH_6 (PF10756.16). | bPH_6 |
Family assigned |
| lprH Rv1418 |
mtbc0_001518 |
lipoprotein LprH | Lipoprotein LprH; a TLR2-stimulating lipoprotein of the M. tuberculosis complex (its over-expression enhances TLR2-dependent HIV infectivity of CD4+ T cells). Cell-envelope lipoprotein; precise molecular function unfixed. | Family assigned | |
| Rv1419 Rv1419 |
mtbc0_001519 |
hypothetical protein | Lectin. Pfam: Ricin_B_lectin (PF00652.29). | Ricin_B_lectin |
Resolved |
| uvrC Rv1420 |
mtbc0_001520 |
excinuclease ABC subunit UvrC | Excinuclease ABC subunit UvrC. Pfam: GIY-YIG (PF01541.31), UvrC_M (PF27096.1), UVR (PF02151.26), UvrC_RNaseH (PF22920.3), UvrC_RNaseH_dom (PF08459.18), HHH_5 (PF14520.13), HHH_2 (PF12826.14), HHH (PF00633.30). | GIY-YIG UvrC_M UVR UvrC_RNaseH UvrC_RNaseH_dom HHH_5 HHH_2 HHH |
Family assigned |
| rapZ Rv1421 |
mtbc0_001521 |
hypothetical protein | RNase adapter RapZ. Pfam: RapZ-like_N (PF03668.22), PapZ_C (PF22740.2). | RapZ-like_N PapZ_C |
Resolved |
| cuvA Rv1422 |
mtbc0_001522 |
hypothetical protein | Carbon utilization/virulence protein CuvA. Pfam: CofD (PF01933.24). | CofD |
Resolved |
| whiA Rv1423 |
mtbc0_001523 |
transcriptional regulator WhiA | DNA-binding protein WhiA. Pfam: WhiA_N (PF10298.15), LAGLIDADG_WhiA (PF14527.12), HTH_WhiA (PF02650.21). | WhiA_N LAGLIDADG_WhiA HTH_WhiA |
Family assigned |
| Rv1424c Rv1424c |
mtbc0_001524 |
membrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1425 Rv1425 |
mtbc0_001525 |
diacyglycerol O-acyltransferase | Wax ester/triacylglycerol synthase family O-acyltransferase. Pfam: WS_DGAT_cat (PF03007.22), WS_DGAT_C (PF06974.19). | WS_DGAT_cat WS_DGAT_C |
Family assigned |
| lipO Rv1426c |
mtbc0_001526 |
esterase LipO | Alpha/beta hydrolase. Pfam: COesterase (PF00135.35), BD-FAE (PF20434.6), Abhydrolase_3 (PF07859.20), Peptidase_S9 (PF00326.28). | COesterase BD-FAE Abhydrolase_3 Peptidase_S9 |
Family assigned |
| fadD12 Rv1427c |
mtbc0_001527 |
acyl-CoA synthetase | Acyl-CoA ligase FadD12. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13). | AMP-binding AMP-binding_C |
Resolved |
| Rv1428c Rv1428c |
mtbc0_001528 |
hypothetical protein | Lysophospholipid acyltransferase family protein. Pfam: Acyltransferase (PF01553.27), DAGAT (PF03982.19). | Acyltransferase DAGAT |
Family assigned |
| Rv1429 Rv1429 |
mtbc0_001529 |
hypothetical protein | PucR family transcriptional regulator. Pfam: RsbRD_N (PF14361.13), GGDEF_2 (PF17853.7), HTH_30 (PF13556.13). | RsbRD_N GGDEF_2 HTH_30 |
Family assigned |