Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1254 Rv1254 |
mtbc0_001343 |
acyltransferase | Acyltransferase. Pfam: Acyl_transf_3 (PF01757.29). | Acyl_transf_3 |
Resolved |
| Rv1255c Rv1255c |
mtbc0_001344 |
HTH-type transcriptional regulator | Helix-turn-helix domain-containing protein. Pfam: TetR_N (PF00440.30). | TetR_N |
Family assigned |
| cyp130 Rv1256c |
mtbc0_001345 |
cytochrome P450 Cyp130 | Cytochrome P450 Cyp130. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv1257c Rv1257c |
mtbc0_001346 |
oxidoreductase | FAD-linked oxidase C-terminal domain-containing protein. Pfam: FAD_binding_4 (PF01565.29), FAD-oxidase_C (PF02913.25). | FAD_binding_4 FAD-oxidase_C |
Family assigned |
| Rv1258c Rv1258c |
mtbc0_001347 |
multidrug-efflux transporter | MFS transporter. Pfam: MFS_1 (PF07690.22), MFS_3 (PF05977.20). | MFS_1 MFS_3 |
Resolved |
| udgB Rv1259 |
- |
uracil DNA glycosylase | Uracil DNA glycosylase. Pfam: UDG (PF03167.26). | UDG |
Resolved |
| Rv1260 Rv1260 |
mtbc0_001349 |
oxidoreductase | FAD-binding protein. Pfam: FAD_binding_3 (PF01494.26). | FAD_binding_3 |
Family assigned |
| Rv1261c Rv1261c |
mtbc0_001350 |
hypothetical protein | F420H(2)-dependent quinone reductase. Pfam: F420H2_quin_red (PF04075.21). | F420H2_quin_red |
Resolved |
| Rv1262c Rv1262c |
mtbc0_001351 |
hypothetical protein | HIT family protein. Pfam: DcpS_C (PF11969.14), HIT (PF01230.30). | DcpS_C HIT |
Family assigned |
| amiB2 Rv1263 |
mtbc0_001352 |
amidase AmiB | Amidase. Pfam: Amidase (PF01425.27). | Amidase |
Resolved |
| Rv1264 Rv1264 |
mtbc0_001353 |
adenylyl cyclase | Adenylate cyclase. Pfam: Ad_Cy_reg (PF16701.11), Guanylate_cyc (PF00211.26). | Ad_Cy_reg Guanylate_cyc |
Resolved |
| Rv1265 Rv1265 |
- |
hypothetical protein | Contains Rv1265_N (PF27105.1), Mb1296_C (PF27540.1) domain(s); putative function inferred from the domain architecture. | Rv1265_N Mb1296_C |
Family assigned |
| pknH Rv1266c |
mtbc0_001355 |
serine/threonine-protein kinase PknH | Serine/threonine protein kinase PknH. Pfam: Pkinase (PF00069.32), PK_Tyr_Ser-Thr (PF07714.24), PknH_C (PF14032.13). | Pkinase PK_Tyr_Ser-Thr PknH_C |
Resolved |
| embR Rv1267c |
mtbc0_001357 |
transcriptional regulator EmbR | Response regulator transcription factor EmbR. Pfam: Trans_reg_C (PF00486.35), BTAD (PF03704.24), Yop-YscD_cpl (PF16697.11), FHA (PF00498.32). | Trans_reg_C BTAD Yop-YscD_cpl FHA |
Resolved |
| Rv1268c Rv1268c |
mtbc0_001358 |
hypothetical protein | C39 family peptidase. Pfam: Peptidase_C39_2 (PF13529.14). | Peptidase_C39_2 |
Family assigned |
| Rv1269c Rv1269c |
mtbc0_001359 |
hypothetical protein | DUF4189; same fold as Rv1813c (PDB 7NHZ); secreted DUF4189-family protein. | DUF4189 |
Family assigned |
| lprA Rv1270c |
mtbc0_001360 |
lipoprotein LprA | TLR2 agonist LprA. Pfam: LppX_LprAFG (PF07161.20). | LppX_LprAFG |
Resolved |
| Rv1271c Rv1271c |
mtbc0_001361 |
hypothetical protein | Secreted protein recognised as an antigen (antibody responses during active TB). Pfam DUF732 (a mycobacterial domain of unknown function). Molecular function unfixed. | DUF732 |
Family assigned |
| Rv1272c Rv1272c |
mtbc0_001362 |
drug ABC transporter ATP-binding protein | Fatty acid ABC transporter ATP-binding protein/permease. Pfam: ABC_membrane (PF00664.29), ABC_tran (PF00005.34). | ABC_membrane ABC_tran |
Family assigned |
| Rv1273c Rv1273c |
mtbc0_001363 |
drug ABC transporter ATP-binding protein | ABC transporter ATP-binding protein. Pfam: ABC_membrane (PF00664.29), ABC_tran (PF00005.34). | ABC_membrane ABC_tran |
Family assigned |
| lprB Rv1274 |
mtbc0_001364 |
lipoprotein LprB | Ribosome-associated heat-shock protein of the Hsp15/RimP-like family (eggNOG COG1188, translation COG category J), containing an S4 RNA-binding domain implicated in 50S-subunit recycling. Ribosome-associated function at family level. | DUF3558 |
Family assigned |
| lprC Rv1275 |
mtbc0_001365 |
lipoprotein LprC | Lipoprotein of the Lpr (LprB/LprC) family. RefSeq product 'lipoprotein LprC'. | DUF3558 |
Family assigned |
| Rv1276c Rv1276c |
- |
hypothetical protein | Contains His_Phos_1 (PF00300.28) domain(s); putative function inferred from the domain architecture. | His_Phos_1 |
Family assigned |
| Rv1277 Rv1277 |
- |
hypothetical protein | Contains Metallophos (PF00149.34) domain(s); putative function inferred from the domain architecture. | Metallophos |
Family assigned |
| Rv1278 Rv1278 |
mtbc0_001368 |
hypothetical protein | AAA family ATPase. Pfam: AAA_15 (PF13175.13), AAA_27 (PF13514.13), AAA_23 (PF13476.13). | AAA_15 AAA_27 AAA_23 |
Family assigned |
| Rv1279 Rv1279 |
mtbc0_001369 |
GMC-type oxidoreductase | GMC family oxidoreductase N-terminal domain-containing protein. Pfam: GMC_oxred_N (PF00732.26), GMC_oxred_C (PF05199.20). | GMC_oxred_N GMC_oxred_C |
Family assigned |
| oppA Rv1280c |
mtbc0_001370 |
oligopeptide ABC transporter substrate-binding lipoprotein OppA | Oligopeptide ABC transporter substrate-binding protein OppA. Pfam: SBP_bac_5 (PF00496.28). | SBP_bac_5 |
Family assigned |
| oppD Rv1281c |
mtbc0_001371 |
oligopeptide ABC transporter ATP-binding protein OppD | ABC transporter ATP-binding protein. Pfam: oligo_HPY (PF08352.18), ABC_tran (PF00005.34). | oligo_HPY ABC_tran |
Family assigned |
| oppC Rv1282c |
mtbc0_001372 |
oligopeptide ABC transporter permease OppC | ABC transporter permease. Pfam: OppC_N (PF12911.13), BPD_transp_1 (PF00528.28). | OppC_N BPD_transp_1 |
Family assigned |
| oppB Rv1283c |
mtbc0_001373 |
oligopeptide ABC transporter permease OppB | ABC transporter permease. Pfam: BPD_transp_1_N (PF19300.5), BPD_transp_1 (PF00528.28). | BPD_transp_1_N BPD_transp_1 |
Family assigned |
| canA Rv1284 |
mtbc0_001374 |
beta-carbonic anhydrase | Beta-carbonic anhydrase CanA. Pfam: Pro_CA (PF00484.25). | Pro_CA |
Resolved |
| cysD Rv1285 |
mtbc0_001375 |
sulfate adenylyltransferase subunit 2 | Sulfate adenylyltransferase subunit CysD. Pfam: PAPS_reduct (PF01507.26). | PAPS_reduct |
Family assigned |
| cysC Rv1286 |
mtbc0_001376 |
adenylyl-sulfate kinase | Adenylyl-sulfate kinase. Pfam: GTP_EFTU (PF00009.34), GTP-eEF1A_C (PF22594.3), APS_kinase (PF01583.27), AAA_33 (PF13671.13). | GTP_EFTU GTP-eEF1A_C APS_kinase AAA_33 |
Resolved |
| Rv1287 Rv1287 |
mtbc0_001377 |
HTH-type transcriptional regulator | RrF2 family transcriptional regulator. Pfam: Rrf2 (PF02082.27). | Rrf2 |
Family assigned |
| Rv1288 Rv1288 |
mtbc0_001378 |
hypothetical protein | Esterase. Pfam: Phage_tail_X (PF05489.19), LysM (PF01476.27), Esterase (PF00756.27). | Phage_tail_X LysM Esterase |
Resolved |
| Rv1289 Rv1289 |
mtbc0_001379 |
hypothetical protein | Contains Rv1289 (PF27329.1) domain(s); putative function inferred from the domain architecture. | Rv1289 |
Family assigned |
| Rv1290A Rv1290A |
- |
hypothetical protein | Leucine carboxyl methyltransferase-family enzyme (eggNOG COG3315, secondary-metabolism COG category Q): a SAM-dependent protein-carboxyl methyltransferase. RefSeq leaves it 'hypothetical protein'. The methyl-acceptor substrate is undetermined. | Family assigned | |
| Rv1290c Rv1290c |
mtbc0_001380 |
hypothetical protein | Polytopic integral membrane protein with 4 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | DUF2254 |
Family assigned |
| Rv1291c Rv1291c |
mtbc0_001382 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF732. Function unknown. Foldseek best (non-significant) hit: 3j9x-assembly1_A A Virus that Infects a Hyperthermophile Encapsidates (prob 0.47, TM 0.55). | DUF732 |
Still unknown |
| argS Rv1292 |
mtbc0_001384 |
arginine--tRNA ligase | Arginine--tRNA ligase. Pfam: Arg_tRNA_synt_N (PF03485.22), tRNA-synt_1d (PF00750.26), tRNA-synt_1 (PF00133.29), DALR_1 (PF05746.22). | Arg_tRNA_synt_N tRNA-synt_1d tRNA-synt_1 DALR_1 |
Resolved |
| lysA Rv1293 |
mtbc0_001385 |
diaminopimelate decarboxylase | Diaminopimelate decarboxylase. Pfam: Orn_Arg_deC_N (PF02784.23), Orn_DAP_Arg_deC (PF00278.29). | Orn_Arg_deC_N Orn_DAP_Arg_deC |
Resolved |
| thrA Rv1294 |
mtbc0_001386 |
homoserine dehydrogenase | Homoserine dehydrogenase. Pfam: NAD_binding_3 (PF03447.23), Homoserine_dh (PF00742.25), ACT (PF01842.32). | NAD_binding_3 Homoserine_dh ACT |
Resolved |
| thrC Rv1295 |
mtbc0_001387 |
threonine synthase | Threonine synthase. Pfam: PALP (PF00291.32). | PALP |
Resolved |
| thrB Rv1296 |
mtbc0_001388 |
homoserine kinase | Homoserine kinase. Pfam: GHMP_kinases_N (PF00288.33), GHMP_kinases_C (PF08544.19). | GHMP_kinases_N GHMP_kinases_C |
Resolved |
| rho Rv1297 |
mtbc0_001389 |
transcription termination factor Rho | Transcription termination factor Rho. Pfam: Rho_N (PF07498.19), Rho_RNA_bind (PF07497.19), ATP-synt_ab (PF00006.32). | Rho_N Rho_RNA_bind ATP-synt_ab |
Resolved |
| rpmE Rv1298 |
mtbc0_001390 |
50S ribosomal protein L31 | 50S ribosomal protein L31. Pfam: Ribosomal_L31 (PF01197.24). | Ribosomal_L31 |
Resolved |
| prfA Rv1299 |
mtbc0_001391 |
peptide chain release factor PrfA | Peptide chain release factor 1. Pfam: PCRF (PF03462.24), RF-1 (PF00472.27). | PCRF RF-1 |
Resolved |
| hemK Rv1300 |
mtbc0_001392 |
release factor glutamine methyltransferase | Peptide chain release factor N(5)-glutamine methyltransferase. Pfam: PrmC_N (PF17827.7), MTS (PF05175.21), Methyltransf_25 (PF13649.13), Methyltransf_31 (PF13847.13), Methyltransf_11 (PF08241.19). | PrmC_N MTS Methyltransf_25 Methyltransf_31 Methyltransf_11 |
Resolved |
| Rv1301 Rv1301 |
mtbc0_001393 |
threonylcarbamoyl-AMP synthase | L-threonylcarbamoyladenylate synthase. Pfam: Sua5_yciO_yrdC (PF01300.25). | Sua5_yciO_yrdC |
Resolved |
| rfe Rv1302 |
mtbc0_001394 |
decaprenyl-phosphate N-acetylglucosaminephosphotransferase | UDP-N-acetylglucosamine--decaprenyl-phosphate N-acetylglucosaminephosphotransferase. Pfam: Glycos_transf_4 (PF00953.27). | Glycos_transf_4 |
Resolved |