Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv0295c Rv0295c |
mtbc0_000314 |
hypothetical protein | Stf0 family sulfotransferase. Pfam: Sulphotransf (PF09037.17). | Sulphotransf |
Family assigned |
| Rv0296c Rv0296c |
- |
sulfatase | Sulfatase. Pfam: Sulfatase (PF00884.29), Phosphodiest (PF01663.28), SGSH_C (PF16347.11). | Sulfatase Phosphodiest SGSH_C |
Resolved |
| PE_PGRS5 Rv0297 |
- |
PE-PGRS family protein PE_PGRS5 | PE-PGRS family protein PE_PGRS5. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| Rv0298 Rv0298 |
mtbc0_000317 |
antitoxin | Ribbon-helix-helix protein%2C CopG family. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Family assigned |
| Rv0299 Rv0299 |
mtbc0_000318 |
toxin | Toxin-antitoxin system toxin. Pfam: Rv0299_toxin (PF27466.1). | Rv0299_toxin |
Resolved |
| vapB2 Rv0300 |
mtbc0_000319 |
antitoxin VapB2 | Type II toxin-antitoxin system antitoxin VapB2. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Resolved |
| vapC2 Rv0301 |
mtbc0_000320 |
ribonuclease VapC2 | PIN domain nuclease. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv0302 Rv0302 |
mtbc0_000321 |
transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_6 (PF13977.12). | TetR_N TetR_C_6 |
Family assigned |
| Rv0303 Rv0303 |
mtbc0_000322 |
dehydrogenase/reductase | Protochlorophyllide reductase. Pfam: KR (PF08659.17), adh_short (PF00106.32), adh_short_C2 (PF13561.13). | KR adh_short adh_short_C2 |
Resolved |
| PPE5 Rv0304c |
- |
PPE family protein PPE5 | PPE family protein PPE5. Pfam: Pentapeptide_2 (PF01469.25). | Pentapeptide_2 |
Family assigned |
| PPE6 Rv0305c |
- |
PPE family protein PPE6 | PPE family protein PPE6. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| bluB Rv0306 |
mtbc0_000326 |
oxidoreductase | 5%2C6-dimethylbenzimidazole synthase. Pfam: Nitroreductase (PF00881.30). | Nitroreductase |
Resolved |
| Rv0307c Rv0307c |
mtbc0_000327 |
hypothetical protein | PH/GRAM-superfamily fold (pleckstrin-homology-like beta-sandwich, typically lipid/membrane-binding); specific function undetermined RefSeq leaves this locus uncharacterised. | Family assigned | |
| Rv0308 Rv0308 |
mtbc0_000328 |
integral membrane protein | Phosphatase PAP2 family protein. Pfam: PAP2 (PF01569.28). | PAP2 |
Family assigned |
| Rv0309 Rv0309 |
mtbc0_000329 |
hypothetical protein | L%2CD-transpeptidase. Pfam: YkuD (PF03734.20). | YkuD |
Resolved |
| Rv0310c Rv0310c |
mtbc0_000330 |
hypothetical protein | Nuclear transport factor 2 family protein. Pfam: SnoaL_4 (PF13577.13). | SnoaL_4 |
Family assigned |
| Rv0311 Rv0311 |
mtbc0_000331 |
hypothetical protein | Longin-like / alpha-beta-plait sensor (ligand-binding) domain; structural homology to DmpR/MopR aromatic-sensing transcriptional regulators, H-NOX gas sensors, and TRAPPC3; specific ligand undetermined RefSeq leaves this locus uncharacterised. | Family assigned | |
| Rv0312 Rv0312 |
mtbc0_000332 |
hypothetical protein | Hsp70 family protein. Pfam: HSP70 (PF00012.27). | HSP70 |
Family assigned |
| Rv0313 Rv0313 |
mtbc0_000333 |
hypothetical protein | Contains Rv0313_N (PF27179.1) domain(s); putative function inferred from the domain architecture. | Rv0313_N |
Family assigned |
| Rv0314c Rv0314c |
- |
membrane protein | Membrane protein. | DUF3060 |
Family assigned |
| Rv0315 Rv0315 |
mtbc0_000335 |
beta-1,3-glucanase | Family 16 glycosylhydrolase. Pfam: Glyco_hydro_16 (PF00722.29). | Glyco_hydro_16 |
Resolved |
| Rv0316 Rv0316 |
mtbc0_000336 |
muconolactone isomerase | Muconolactone Delta-isomerase family protein. Pfam: MIase (PF02426.23). | MIase |
Family assigned |
| glpQ2 Rv0317c |
mtbc0_000337 |
glycerophosphoryl diester phosphodiesterase GlpQ | Glycerophosphodiester phosphodiesterase. Pfam: GDPD (PF03009.24). | GDPD |
Resolved |
| Rv0318c Rv0318c |
- |
integral membrane protein | Integral membrane protein. Pfam: Zip (PF02535.29). | Zip |
Family assigned |
| pcp Rv0319 |
mtbc0_000340 |
pyrrolidone-carboxylate peptidase | Pyroglutamyl-peptidase I. Pfam: Peptidase_C15 (PF01470.23). | Peptidase_C15 |
Resolved |
| Rv0320 Rv0320 |
mtbc0_000341 |
hypothetical protein | Contains VldE (PF26571.1) domain(s); putative function inferred from the domain architecture. | VldE |
Family assigned |
| dcd Rv0321 |
mtbc0_000342 |
deoxycytidine triphosphate deaminase | DCTP deaminase. Pfam: DCD (PF22769.2), DCD_N (PF06559.17), DCD_C (PF22569.2), dUTPase (PF00692.25). | DCD DCD_N DCD_C dUTPase |
Resolved |
| udgA Rv0322 |
mtbc0_000343 |
UDP-glucose 6-dehydrogenase UdgA | UDP-glucose/GDP-mannose dehydrogenase family protein. Pfam: UDPG_MGDP_dh_N (PF03721.21), UDPG_MGDP_dh (PF00984.25), UDPG_MGDP_dh_C (PF03720.23). | UDPG_MGDP_dh_N UDPG_MGDP_dh UDPG_MGDP_dh_C |
Family assigned |
| Rv0323c Rv0323c |
mtbc0_000344 |
hypothetical protein | PIG-L deacetylase family protein. Pfam: PIG-L (PF02585.23). | PIG-L |
Family assigned |
| Rv0324 Rv0324 |
mtbc0_000345 |
transcriptional regulator | Metalloregulator ArsR/SmtB family transcription factor. Pfam: HTH_5 (PF01022.27), HTH_IclR (PF09339.17), Rhodanese (PF00581.26). | HTH_5 HTH_IclR Rhodanese |
Family assigned |
| Rv0325 Rv0325 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 5u0p-assembly1_V Cryo-EM structure of the transcriptional Mediator (prob 0.02, TM 0.31). | Still unknown | |
| Rv0326 Rv0326 |
- |
hypothetical protein | Contains Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19) domain(s); putative function inferred from the domain architecture. | Methyltransf_25 Methyltransf_11 |
Family assigned |
| cyp135A1 Rv0327c |
mtbc0_000347 |
cytochrome P450 Cyp135A1 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv0328 Rv0328 |
mtbc0_000348 |
transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_6 (PF13977.12), TetR_C_31 (PF17940.7). | TetR_N TetR_C_6 TetR_C_31 |
Family assigned |
| Rv0329c Rv0329c |
mtbc0_000349 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: Methyltransf_23 (PF13489.13), Methyltransf_31 (PF13847.13), Ubie_methyltran (PF01209.25), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Methyltransf_23 Methyltransf_31 Ubie_methyltran Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Resolved |
| Rv0330c Rv0330c |
mtbc0_000350 |
hypothetical protein | Helix-turn-helix domain-containing protein. Pfam: TetR_N (PF00440.30). | TetR_N |
Family assigned |
| Rv0331 Rv0331 |
mtbc0_000351 |
dehydrogenase/reductase | FAD/NAD(P)-binding oxidoreductase. Pfam: Pyr_redox_2 (PF07992.21). | Pyr_redox_2 |
Resolved |
| Rv0332 Rv0332 |
- |
hypothetical protein | Contains MDMPI_N (PF11716.14), MDMPI_C (PF07398.17) domain(s); putative function inferred from the domain architecture. | MDMPI_N MDMPI_C |
Family assigned |
| Rv0333 Rv0333 |
mtbc0_000353 |
hypothetical protein | Nuclear transport factor 2 family protein. Pfam: SnoaL_2 (PF12680.14). | SnoaL_2 |
Family assigned |
| rmlA Rv0334 |
mtbc0_000354 |
glucose-1-phosphate thymidylyltransferase | Glucose-1-phosphate thymidylyltransferase RfbA. Pfam: NTP_transferase (PF00483.30), NTP_transf_3 (PF12804.14). | NTP_transferase NTP_transf_3 |
Resolved |
| PE6 Rv0335c |
- |
PE family protein PE6 | PE family protein PE6. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv0336 Rv0336 |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF222. Function unknown. | DUF222 |
Still unknown |
| aspC Rv0337c |
mtbc0_000357 |
aspartate aminotransferase | Pyridoxal phosphate-dependent aminotransferase. Pfam: Aminotran_1_2 (PF00155.28), DegT_DnrJ_EryC1 (PF01041.24). | Aminotran_1_2 DegT_DnrJ_EryC1 |
Resolved |
| Rv0338c Rv0338c |
mtbc0_000358 |
iron-sulfur-binding reductase | Heterodisulfide reductase-related iron-sulfur binding cluster. Pfam: Fer4_10 (PF13237.12), Fer4_9 (PF13187.12), CCG (PF02754.22). | Fer4_10 Fer4_9 CCG |
Resolved |
| iniR Rv0339c |
mtbc0_000359 |
transcriptional regulator | Isoniazid response ATPase/transcriptional regulator IniR. Pfam: GerE (PF00196.26). | GerE |
Family assigned |
| Rv0340 Rv0340 |
mtbc0_000360 |
hypothetical protein | Rv0340 family IniB-related protein. Pfam: IniB (PF27122.1). | IniB |
Family assigned |
| iniB Rv0341 |
mtbc0_000361 |
isoniazid inducible protein IniB | Isoniazid-induced protein IniB. Pfam: IniB (PF27122.1). | IniB |
Resolved |
| iniA Rv0342 |
- |
isoniazid inductible protein IniA | Isoniazid inductible protein IniA. Pfam: Dynamin_N (PF00350.30). | Dynamin_N |
Resolved |
| iniC Rv0343 |
mtbc0_000363 |
iIsoniazid inductible protein IniC | Isoniazid-induced dynamin-like GTPase IniC. Pfam: MMR_HSR1 (PF01926.30), Dynamin_N (PF00350.30). | MMR_HSR1 Dynamin_N |
Resolved |
| lpqJ Rv0344c |
mtbc0_000364 |
lipoprotein LpqJ | Lipoprotein LpqJ with an LpqN/LpqE-like lipid-binding fold; possible association with the respiratory supercomplex RefSeq leaves this locus uncharacterised. | Family assigned |