Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| kdpC Rv1031 |
mtbc0_001110 |
potassium-transporting ATPase subunit C | K(+)-transporting ATPase subunit C. Pfam: KdpC (PF02669.21). | KdpC |
Family assigned |
| trcS Rv1032c |
mtbc0_001111 |
two component sensor histidine kinase TrcS | HAMP domain-containing sensor histidine kinase. Pfam: HisKA (PF00512.32), HATPase_c (PF02518.32). | HisKA HATPase_c |
Family assigned |
| trcR Rv1033c |
mtbc0_001112 |
two component transcriptional regulator TrcR | Two-component system response regulator TrcR. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| esxI Rv1037c |
mtbc0_001114 |
ESAT-6 like protein EsxI | Type VII secretion system ESX-5 protein EsxL. Pfam: WXG100 (PF06013.19). | WXG100 |
Resolved |
| esxJ Rv1038c |
mtbc0_001115 |
ESAT-6 like protein EsxJ | Type VII secretion system ESX-5 protein EsxJ. Pfam: WXG100 (PF06013.19). | WXG100 |
Resolved |
| PPE15 Rv1039c |
- |
PPE family protein PPE15 | PPE family protein PPE15. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| PE8 Rv1040c |
- |
PE family protein PE8 | PE family protein PE8. Pfam: PE (PF00934.26), PPE-SVP (PF12484.14). | PE PPE-SVP |
Family assigned |
| Rv1041c Rv1041c |
- |
IS2-like transposase | IS2-like transposase. Pfam: DDE_Tnp_1 (PF01609.28). | DDE_Tnp_1 |
Resolved |
| Rv1042c Rv1042c |
- |
IS2-like transposase | IS2-like transposase. | DUF4096 |
Resolved |
| Rv1043c Rv1043c |
mtbc0_001120 |
hypothetical protein | Serine protease. Pfam: Trypsin (PF00089.33), Trypsin_2 (PF13365.13). | Trypsin Trypsin_2 |
Resolved |
| Rv1044 Rv1044 |
mtbc0_001121 |
hypothetical protein | MenA3 / TakA, a kinase antitoxin of the MenAT3 module that neutralises its cognate toxin by phosphorylation. RefSeq names only 'AbiEi family antitoxin domain protein'; the kinase mechanism was shown by Yu 2020. | AbiEi_4 |
Resolved |
| Rv1045 Rv1045 |
mtbc0_001122 |
hypothetical protein | MenT3 (TglT), a DUF1814 nucleotidyltransferase toxin of the MenAT3 module that blocks translation by tRNA inactivation. RefSeq names only the generic 'AbiEii/AbiGii toxin family'; the MenT3 toxin identity is established (Cai 2020). | AbiEii |
Resolved |
| Rv1046c Rv1046c |
|
Hypothetical protein | — | Still unknown | |
| Rv1047 Rv1047 |
mtbc0_001123 |
transposase | IS256-like element IS1081 family transposase. Pfam: Transposase_mut (PF00872.25). | Transposase_mut |
Family assigned |
| Rv1048c Rv1048c |
mtbc0_001124 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 4rgu-assembly1_A-2 Crystal Structure of Putative MarR Family Transcrip (prob 0.95, TM 0.60). | Still unknown | |
| Rv1049 Rv1049 |
mtbc0_001126 |
transcriptional repressor | Oxidation-sensing regulator MosR. Pfam: MarR_2 (PF12802.14), HTH_Crp_2 (PF13545.13). | MarR_2 HTH_Crp_2 |
Resolved |
| Rv1050 Rv1050 |
mtbc0_001127 |
oxidoreductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv1051c Rv1051c |
- |
hypothetical protein | Contains AbiEii (PF08843.18), HTH_17 (PF12728.14) domain(s); putative function inferred from the domain architecture. | AbiEii HTH_17 |
Family assigned |
| Rv1052 Rv1052 |
- |
hypothetical protein | Nucleotidyltransferase (eggNOG COG2184, COG category D): a polymerase-beta-like nucleotidyltransferase, often associated with DNA repair / cell-division functions. RefSeq leaves it 'hypothetical protein'. The acceptor/substrate is undetermined. | Family assigned | |
| Rv1053c Rv1053c |
|
Hypothetical protein | — | Still unknown | |
| Rv1056 Rv1056 |
mtbc0_001135 |
hypothetical protein | DUF427 domain-containing protein. Pfam: NTP_transf_9 (PF04248.20). | NTP_transf_9 |
Family assigned |
| Rv1057 Rv1057 |
mtbc0_001137 |
hypothetical protein | YncE family protein. | Family assigned | |
| fadD14 Rv1058 |
mtbc0_001138 |
fatty-acid--CoA ligase FadD14 | Long-chain fatty acid--CoA ligase. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13). | AMP-binding AMP-binding_C |
Resolved |
| Rv1059 Rv1059 |
mtbc0_001139 |
hypothetical protein | Dihydrodipicolinate reductase. Pfam: DapB_N (PF01113.27), DAP_DH_C (PF19328.5). | DapB_N DAP_DH_C |
Resolved |
| Rv1060 Rv1060 |
mtbc0_001140 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1061 Rv1061 |
mtbc0_001141 |
hypothetical protein | Class II glutamine amidotransferase. Pfam: GATase_4 (PF13230.12), GATase_6 (PF13522.12). | GATase_4 GATase_6 |
Resolved |
| Rv1062 Rv1062 |
mtbc0_001142 |
hypothetical protein | Patatin-like phospholipase family protein. Pfam: Patatin (PF01734.28). | Patatin |
Family assigned |
| Rv1063c Rv1063c |
mtbc0_001143 |
NTE family protein | Patatin family protein. Pfam: Patatin (PF01734.28). | Patatin |
Family assigned |
| lpqV Rv1064c |
mtbc0_001144 |
lipoprotein LpqV | Lipoprotein LpqV. Pfam: LpqV (PF17301.8). | LpqV |
Resolved |
| Rv1065 Rv1065 |
mtbc0_001145 |
hypothetical protein | Cysteine dioxygenase family protein. Pfam: CDO_I (PF05995.19). | CDO_I |
Family assigned |
| Rv1066 Rv1066 |
mtbc0_001146 |
hypothetical protein | Rhodanese-like domain-containing protein. Pfam: Rhodanese (PF00581.26). | Rhodanese |
Family assigned |
| PE_PGRS19 Rv1067c |
- |
PE-PGRS family protein PE_PGRS19 | PE-PGRS family protein PE_PGRS19. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| PE_PGRS20 Rv1068c |
- |
PE-PGRS family protein PE_PGRS20 | PE-PGRS family protein PE_PGRS20. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| Rv1069c Rv1069c |
mtbc0_001149 |
hypothetical protein | Alpha/beta-hydrolase family protein. Pfam: Abhydrolase_9_N (PF15420.12), Abhydrolase_9 (PF10081.16). | Abhydrolase_9_N Abhydrolase_9 |
Family assigned |
| echA8 Rv1070c |
mtbc0_001150 |
enoyl-CoA hydratase EchA8 | Enoyl-CoA hydratase. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Resolved |
| echA9 Rv1071c |
mtbc0_001151 |
enoyl-CoA hydratase EchA9 | Enoyl-CoA hydratase/isomerase family protein. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Family assigned |
| Rv1072 Rv1072 |
mtbc0_001152 |
transmembrane protein | Bax inhibitor-1/YccA family protein. Pfam: BaxI_1 (PF12811.13), Bax1-I (PF01027.27). | BaxI_1 Bax1-I |
Family assigned |
| Rv1073 Rv1073 |
mtbc0_001153 |
hypothetical protein | Nicking-endonuclease-like fold (type-II nicking enzyme V.NaeI-like). RefSeq leaves it 'hypothetical protein'. | Family assigned | |
| fadA3 Rv1074c |
mtbc0_001154 |
beta-ketoacyl CoA thiolase FadA | Acetyl-CoA C-acetyltransferase. Pfam: Thiolase_N (PF00108.30), Thiolase_C (PF02803.25). | Thiolase_N Thiolase_C |
Resolved |
| Rv1075c Rv1075c |
mtbc0_001155 |
hypothetical protein | SGNH/GDSL hydrolase family protein. Pfam: Lipase_GDSL (PF00657.29), Lipase_GDSL_2 (PF13472.13). | Lipase_GDSL Lipase_GDSL_2 |
Family assigned |
| lipU Rv1076 |
- |
lipase LipU | Lipase LipU. Pfam: BD-FAE (PF20434.6), Say1_Mug180 (PF10340.16), Abhydrolase_3 (PF07859.20). | BD-FAE Say1_Mug180 Abhydrolase_3 |
Resolved |
| cbs Rv1077 |
- |
cystathionine beta-synthase | Cystathionine beta-synthase. Pfam: PALP (PF00291.32), CBS (PF00571.34). | PALP CBS |
Resolved |
| pra Rv1078 |
mtbc0_001158 |
hypothetical protein | RDD family protein. Pfam: RDD (PF06271.19). | RDD |
Family assigned |
| metB Rv1079 |
mtbc0_001159 |
cystathionine gamma-synthase | Cystathionine gamma-synthase. Pfam: Cys_Met_Meta_PP (PF01053.27), Met_gamma_lyase (PF06838.18), DegT_DnrJ_EryC1 (PF01041.24), Aminotran_1_2 (PF00155.28). | Cys_Met_Meta_PP Met_gamma_lyase DegT_DnrJ_EryC1 Aminotran_1_2 |
Resolved |
| greA Rv1080c |
- |
transcription elongation factor GreA | Transcription elongation factor GreA. Pfam: GreA_GreB_N (PF03449.21), GreA_GreB (PF01272.26). | GreA_GreB_N GreA_GreB |
Resolved |
| Rv1081c Rv1081c |
mtbc0_001161 |
membrane protein | Conserved hypothetical protein; DUF domain(s) DUF4307. Function unknown. | DUF4307 |
Still unknown |
| mca Rv1082 |
mtbc0_001162 |
mycothiol S-conjugate amidase | Mycothiol conjugate amidase Mca. Pfam: PIG-L (PF02585.23). | PIG-L |
Resolved |
| Rv1083 Rv1083 |
mtbc0_001163 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1084 Rv1084 |
mtbc0_001164 |
hypothetical protein | Thioredoxin domain-containing protein. Pfam: Thioredox_DsbH (PF03190.22), Thioredoxin_7 (PF13899.13). | Thioredox_DsbH Thioredoxin_7 |
Family assigned |
| Rv1085c Rv1085c |
mtbc0_001165 |
hemolysin-like protein | Hemolysin III family protein. Pfam: HlyIII (PF03006.27). | HlyIII |
Family assigned |