Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv0493c Rv0493c |
- |
hypothetical protein | Contains Tocopherol_cycl (PF14249.13) domain(s); putative function inferred from the domain architecture. | Tocopherol_cycl |
Family assigned |
| Rv0494 Rv0494 |
- |
HTH-type transcriptional regulator | HTH-type transcriptional regulator. Pfam: GntR (PF00392.28), HTH_Crp_2 (PF13545.13), FCD (PF07729.18). | GntR HTH_Crp_2 FCD |
Family assigned |
| Rv0495c Rv0495c |
- |
hypothetical protein | Contains Rv0495c (PF11307.14) domain(s); putative function inferred from the domain architecture. | Rv0495c |
Family assigned |
| Rv0496 Rv0496 |
- |
hypothetical protein | Contains Ppx-GppA (PF02541.23) domain(s); putative function inferred from the domain architecture. | Ppx-GppA |
Family assigned |
| Rv0497 Rv0497 |
mtbc0_000523 |
transmembrane protein | Contains Rv0497_C (PF27548.1) domain(s); putative function inferred from the domain architecture. | Rv0497_C |
Family assigned |
| Rv0498 Rv0498 |
mtbc0_000524 |
hypothetical protein | Sugar phosphate isomerase/epimerase. Pfam: AP_endonuc_2 (PF01261.31). | AP_endonuc_2 |
Resolved |
| Rv0499 Rv0499 |
mtbc0_000525 |
hypothetical protein | Thioesterase family protein. Pfam: 4HBT_3 (PF13622.13), 4HBT_3C (PF20789.4). | 4HBT_3 4HBT_3C |
Family assigned |
| proC Rv0500 |
- |
pyrroline-5-carboxylate reductase | Pyrroline-5-carboxylate reductase. Pfam: F420_oxidored (PF03807.24), NAD_binding_2 (PF03446.22), P5CR_dimer (PF14748.12). | F420_oxidored NAD_binding_2 P5CR_dimer |
Resolved |
| Rv0500A Rv0500A |
- |
DNA-binding protein | DNA-binding protein. Pfam: HTH_17 (PF12728.14). | HTH_17 |
Family assigned |
| galE2 Rv0501 |
mtbc0_000529 |
UDP-glucose 4-epimerase GalE | SDR family oxidoreductase. Pfam: Epimerase (PF01370.28), GDP_Man_Dehyd (PF16363.12), 3Beta_HSD (PF01073.26). | Epimerase GDP_Man_Dehyd 3Beta_HSD |
Family assigned |
| Rv0502 Rv0502 |
mtbc0_000530 |
hypothetical protein | Lysophospholipid acyltransferase family protein. Pfam: Acyltransferase (PF01553.27). | Acyltransferase |
Family assigned |
| cmaA2 Rv0503c |
mtbc0_000531 |
cyclopropane mycolic acid synthase | Cyclopropane mycolic acid synthase CmaA2. Pfam: CMAS (PF02353.27), Methyltransf_23 (PF13489.13), Methyltransf_12 (PF08242.19), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19). | CMAS Methyltransf_23 Methyltransf_12 Methyltransf_25 Methyltransf_11 |
Resolved |
| Rv0504c Rv0504c |
mtbc0_000532 |
hypothetical protein | MaoC family dehydratase N-terminal domain-containing protein. Pfam: FAS1_DH_region (PF13452.12). | FAS1_DH_region |
Family assigned |
| serB1 Rv0505c |
- |
phosphoserine phosphatase SerB | Phosphoserine phosphatase SerB. Pfam: Hydrolase (PF00702.33), HAD (PF12710.14), Hydrolase_3 (PF08282.19). | Hydrolase HAD Hydrolase_3 |
Resolved |
| mmpS2 Rv0506 |
mtbc0_000534 |
membrane protein MmpS2 | MmpS family protein. Pfam: Mycobact_memb (PF05423.19). | Mycobact_memb |
Family assigned |
| mmpL2 Rv0507 |
mtbc0_000535 |
transmembrane transport protein MmpL2 | RND transporter MmpL2. Pfam: MMPL (PF03176.22). | MMPL |
Resolved |
| Rv0508 Rv0508 |
mtbc0_000536 |
hypothetical protein | Glutaredoxin family protein. Pfam: Glrx-like (PF05768.21). | Glrx-like |
Family assigned |
| hemA Rv0509 |
mtbc0_000537 |
glutamyl-tRNA reductase | Glutamyl-tRNA reductase. Pfam: GlutR_N (PF05201.21), Shikimate_DH (PF01488.27), GlutR_dimer (PF00745.26). | GlutR_N Shikimate_DH GlutR_dimer |
Resolved |
| hemC Rv0510 |
mtbc0_000538 |
porphobilinogen deaminase | Hydroxymethylbilane synthase. Pfam: Porphobil_deam (PF01379.26), Porphobil_deamC (PF03900.21). | Porphobil_deam Porphobil_deamC |
Resolved |
| hemD Rv0511 |
- |
uroporphyrin-III C-methyltransferase | Uroporphyrin-III C-methyltransferase. Pfam: TP_methylase (PF00590.26), HEM4 (PF02602.21). | TP_methylase HEM4 |
Resolved |
| hemB Rv0512 |
mtbc0_000540 |
delta-aminolevulinic acid dehydratase | Porphobilinogen synthase. Pfam: ALAD (PF00490.28). | ALAD |
Resolved |
| Rv0513 Rv0513 |
mtbc0_000541 |
transmembrane protein | DUF3093 domain-containing protein. Pfam: UCP026610 (PF27726.1). | UCP026610 |
Family assigned |
| Rv0514 Rv0514 |
mtbc0_000542 |
transmembrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0515 Rv0515 |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF222. Function unknown. | DUF222 |
Still unknown |
| oprA Rv0516c |
mtbc0_000544 |
anti-anti-sigma factor | Osmosensory protein OprA. Pfam: STAS (PF01740.27), STAS_2 (PF13466.13). | STAS STAS_2 |
Resolved |
| Rv0517 Rv0517 |
- |
acyltransferase | Acyltransferase. Pfam: Acyl_transf_3 (PF01757.29). | Acyl_transf_3 |
Resolved |
| Rv0518 Rv0518 |
mtbc0_000546 |
hypothetical protein | SGNH/GDSL hydrolase family protein. Pfam: Lipase_GDSL (PF00657.29), Lipase_GDSL_2 (PF13472.13). | Lipase_GDSL Lipase_GDSL_2 |
Family assigned |
| Rv0519c Rv0519c |
- |
membrane protein | Membrane protein. Pfam: Esterase (PF00756.27). | Esterase |
Family assigned |
| gabP Rv0522 |
- |
GABA permease GabP | GABA permease GabP. Pfam: AA_permease (PF00324.28), AA_permease_2 (PF13520.13), Spore_permease (PF03845.20). | AA_permease AA_permease_2 Spore_permease |
Resolved |
| Rv0523c Rv0523c |
mtbc0_000551 |
hypothetical protein | Nitroreductase family deazaflavin-dependent oxidoreductase. | Family assigned | |
| hemL Rv0524 |
mtbc0_000552 |
glutamate-1-semialdehyde 2,1-aminomutase | Glutamate-1-semialdehyde 2%2C1-aminomutase. Pfam: Aminotran_3 (PF00202.28). | Aminotran_3 |
Resolved |
| Rv0525 Rv0525 |
mtbc0_000553 |
hypothetical protein | Histidine phosphatase family protein. Pfam: His_Phos_1 (PF00300.28). | His_Phos_1 |
Family assigned |
| Rv0526 Rv0526 |
- |
thioredoxin | Thioredoxin. Pfam: Redoxin (PF08534.17), AhpC-TSA (PF00578.28), Thioredoxin (PF00085.27). | Redoxin AhpC-TSA Thioredoxin |
Resolved |
| ccdA Rv0527 |
- |
cytochrome C-type biogenesis protein CcdA | Cytochrome C-type biogenesis protein CcdA. | Resolved | |
| Rv0528 Rv0528 |
mtbc0_000556 |
transmembrane protein | Cytochrome c biogenesis protein ResB. Pfam: ResB (PF05140.20). | ResB |
Resolved |
| ccsA Rv0529 |
mtbc0_000557 |
cytochrome C-type biogenesis protein CcsA | C-type cytochrome biogenesis protein CcsB. Pfam: Cytochrom_C_asm (PF01578.26). | Cytochrom_C_asm |
Resolved |
| Rv0530 Rv0530 |
mtbc0_000558 |
hypothetical protein | MinD/ParA family protein. Pfam: CbiA (PF01656.30), AAA_31 (PF13614.13), CBP_BcsQ (PF06564.19). | CbiA AAA_31 CBP_BcsQ |
Family assigned |
| Rv0530A Rv0530A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0531 Rv0531 |
mtbc0_000560 |
membrane protein | Conserved hypothetical protein; DUF domain(s) DUF4229. Function unknown. | DUF4229 |
Still unknown |
| PE_PGRS6 Rv0532 |
- |
PE-PGRS family protein PE_PGRS6 | PE-PGRS family protein PE_PGRS6. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| fabH Rv0533c |
mtbc0_000562 |
3-oxoacyl-ACP synthase III | Beta-ketoacyl-ACP synthase III. Pfam: Thiolase_N (PF00108.30), ACP_syn_III (PF08545.17), ACP_syn_III_C (PF08541.17). | Thiolase_N ACP_syn_III ACP_syn_III_C |
Resolved |
| menA Rv0534c |
mtbc0_000563 |
1,4-dihydroxy-2-naphthoate octaprenyltransferase | 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase. Pfam: UbiA (PF01040.24). | UbiA |
Resolved |
| Rv0535 Rv0535 |
- |
5'-methylthioadenosine phosphorylase | 5'-methylthioadenosine phosphorylase. Pfam: PNP_UDP_1 (PF01048.27). | PNP_UDP_1 |
Resolved |
| galE3 Rv0536 |
- |
UDP-glucose 4-epimerase GalE | UDP-glucose 4-epimerase GalE. Pfam: GDP_Man_Dehyd (PF16363.12), Epimerase (PF01370.28). | GDP_Man_Dehyd Epimerase |
Resolved |
| Rv0537c Rv0537c |
mtbc0_000566 |
integral membrane protein | Conserved hypothetical protein; DUF domain(s) DUF7937. Function unknown. | DUF7937 |
Still unknown |
| ptrp Rv0538 |
mtbc0_000567 |
membrane protein | Proline-threonine repetitive protein (PTRP), an M. tuberculosis-complex-specific cell-wall protein with tandem amino-acid repeats; a serologically immunodominant antigen expressed in vivo during (pre)clinical TB. Molecular/enzymatic function unknown. RefSeq leaves it 'membrane protein'. | DUF7159 |
Family assigned |
| Rv0539 Rv0539 |
- |
dolichyl-phosphate sugar synthase | Dolichyl-phosphate sugar synthase. Pfam: Glycos_transf_2 (PF00535.33). | Glycos_transf_2 |
Resolved |
| Rv0540 Rv0540 |
mtbc0_000569 |
hypothetical protein | DUF2064; fold of a putative nucleotide-diphospho-sugar transferase (PDB 3CGX); putative sugar/nucleotidyl transferase. | DUF2064 |
Family assigned |
| Rv0541c Rv0541c |
mtbc0_000570 |
integral membrane protein | Integral membrane protein. | Family assigned | |
| menE Rv0542c |
mtbc0_000571 |
2-succinylbenzoic acid--CoA ligase | O-succinylbenzoate--CoA ligase. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13). | AMP-binding AMP-binding_C |
Resolved |